{"id":997,"date":"2025-05-29T09:49:57","date_gmt":"2025-05-29T09:49:57","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-chiet-xuat-ha-thu-o-do-gerbex-polygonum\/"},"modified":"2026-09-28T20:45:08","modified_gmt":"2026-09-28T13:45:08","slug":"nguyen-lieu-chiet-xuat-ha-thu-o-do-gerbex-polygonum","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-chiet-xuat-ha-thu-o-do-gerbex-polygonum\/","title":{"rendered":"Chi\u1ebft xu\u1ea5t h\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf (Polygonum multiflorum): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Chi\u1ebft xu\u1ea5t h\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf (Polygonum multiflorum): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng<\/h1>\n<p><strong>Chi\u1ebft xu\u1ea5t h\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf<\/strong> l\u00e0 cao chi\u1ebft t\u1eeb r\u1ec5 c\u1ee7 c\u00e2y h\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf (<em>Reynoutria multiflora<\/em>, t\u00ean c\u0169 <em>Polygonum multiflorum<\/em>). \u0110\u00e2y l\u00e0 d\u01b0\u1ee3c li\u1ec7u c\u1ea7n \u0111\u1eb7c bi\u1ec7t l\u01b0u \u00fd v\u1ec1 <strong>an to\u00e0n v\u1edbi gan<\/strong>, v\u00e0 c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t l\u1edbn gi\u1eefa d\u1ea1ng <strong>s\u1ed1ng<\/strong> v\u00e0 d\u1ea1ng <strong>\u0111\u00e3 ch\u1ebf bi\u1ebfn<\/strong> (ch\u1ebf v\u1edbi \u0111\u1eadu \u0111en).<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>H\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf, d\u1ea1 giao \u0111\u1eb1ng (d\u00e2y), He shou wu, fo-ti; Polygoni multiflori radix<\/td>\n<\/tr>\n<tr>\n<td>Lo\u00e0i<\/td>\n<td><em>Reynoutria multiflora (Thunb.) Moldenke (Polygonum multiflorum Thunb., Fallopia multiflora)<\/em>, h\u1ecd Rau r\u0103m (Polygonaceae)<\/td>\n<\/tr>\n<tr>\n<td>B\u1ed9 ph\u1eadn d\u00f9ng<\/td>\n<td>R\u1ec5 c\u1ee7<\/td>\n<\/tr>\n<tr>\n<td>Chuy\u00ean lu\u1eadn<\/td>\n<td>D\u01b0\u1ee3c \u0111i\u1ec3n Vi\u1ec7t Nam V: H\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf (r\u1ec5 c\u1ee7); H\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf \u0111\u00e3 ch\u1ebf bi\u1ebfn<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ho\u1ea1t ch\u1ea5t ch\u00ednh<\/td>\n<td>Stilben glycosid (2,3,5,4&#8242;-tetrahydroxystilben-2-O-glucosid \u2013 THSG), anthraquinon (emodin, physcion)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u00e2y v\u00e0 d\u01b0\u1ee3c li\u1ec7u<\/h2>\n<p>H\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf l\u00e0 d\u00e2y leo s\u1ed1ng l\u00e2u n\u0103m, l\u00e1 h\u00ecnh tim, r\u1ec5 ph\u00ecnh th\u00e0nh c\u1ee7 m\u00e0u n\u00e2u \u0111\u1ecf, ru\u1ed9t c\u00f3 v\u00e2n. Theo \u0110\u00f4ng y, c\u1ee7 d\u00f9ng l\u00e0m thu\u1ed1c ph\u1ea3i \u0111\u01b0\u1ee3c <strong>ch\u1ebf bi\u1ebfn<\/strong>: ng\u00e2m n\u01b0\u1edbc vo g\u1ea1o, \u0111\u1ed3 v\u1edbi n\u01b0\u1edbc \u0111\u1eadu \u0111en nhi\u1ec1u l\u1ea7n. D\u01b0\u1ee3c \u0111i\u1ec3n Vi\u1ec7t Nam c\u00f3 chuy\u00ean lu\u1eadn ri\u00eang cho d\u1ea1ng \u0111\u00e3 ch\u1ebf bi\u1ebfn. C\u1ea7n ph\u00e2n bi\u1ec7t v\u1edbi h\u00e0 th\u1ee7 \u00f4 tr\u1eafng (<em>Streptocaulon juventas<\/em>), m\u1ed9t c\u00e2y kh\u00e1c.<\/p>\n<h2>Th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc<\/h2>\n<ul>\n<li><strong>Stilben glycosid<\/strong>: THSG (2,3,5,4&#8242;-tetrahydroxystilben-2-O-\u03b2-D-glucosid), ch\u1ea5t \u0111\u00e1nh d\u1ea5u ch\u00ednh.<\/li>\n<li><strong>Anthraquinon<\/strong>: emodin, physcion, chrysophanol v\u00e0 glycosid; h\u00e0m l\u01b0\u1ee3ng gi\u1ea3m sau ch\u1ebf bi\u1ebfn.<\/li>\n<li>Tanin, lecithin.<\/li>\n<\/ul>\n<h2>Chi\u1ebft xu\u1ea5t v\u00e0 ti\u00eau chu\u1ea9n h\u00f3a<\/h2>\n<p>R\u1ec5 c\u1ee7 (s\u1ed1ng ho\u1eb7c \u0111\u00e3 ch\u1ebf) \u0111\u01b0\u1ee3c chi\u1ebft b\u1eb1ng n\u01b0\u1edbc ho\u1eb7c ethanol \u2013 n\u01b0\u1edbc, c\u00f4 \u0111\u1eb7c th\u00e0nh cao l\u1ecfng, cao kh\u00f4 (d\u1ea1ng chi\u1ebft l\u1ecfng trong glycol d\u00f9ng cho m\u1ef9 ph\u1ea9m ch\u0103m s\u00f3c t\u00f3c). Nguy\u00ean li\u1ec7u n\u00ean ghi r\u00f5 <strong>d\u1ea1ng s\u1ed1ng hay \u0111\u00e3 ch\u1ebf bi\u1ebfn<\/strong>, h\u00e0m l\u01b0\u1ee3ng THSG v\u00e0 anthraquinon.<\/p>\n<h2>Ch\u1ec9 ti\u00eau ch\u1ea5t l\u01b0\u1ee3ng n\u00ean xem<\/h2>\n<ul>\n<li>THSG, emodin, t\u1ed5ng anthraquinon (HPLC); d\u1ea1ng s\u1ed1ng hay \u0111\u00e3 ch\u1ebf bi\u1ebfn.<\/li>\n<li>Kim lo\u1ea1i n\u1eb7ng, vi sinh v\u1eadt, d\u01b0 l\u01b0\u1ee3ng thu\u1ed1c b\u1ea3o v\u1ec7 th\u1ef1c v\u1eadt; \u0111\u1ed9c t\u1ed1 vi n\u1ea5m v\u1edbi d\u01b0\u1ee3c li\u1ec7u d\u1ec5 m\u1ed1c.<\/li>\n<\/ul>\n<h2>Applications<\/h2>\n<ul>\n<li>Thu\u1ed1c d\u01b0\u1ee3c li\u1ec7u, th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe (theo quy \u0111\u1ecbnh).<\/li>\n<li>M\u1ef9 ph\u1ea9m ch\u0103m s\u00f3c t\u00f3c (d\u1ea1ng chi\u1ebft l\u1ecfng d\u00f9ng ngo\u00e0i).<\/li>\n<li>C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n<h2>An to\u00e0n v\u00e0 l\u01b0u \u00fd<\/h2>\n<ul>\n<li>Nhi\u1ec1u qu\u1ed1c gia (Anh, \u00dac, Trung Qu\u1ed1c, Nh\u1eadt B\u1ea3n\u2026) \u0111\u00e3 ghi nh\u1eadn c\u00e1c ca <strong>t\u1ed5n th\u01b0\u01a1ng gan<\/strong> li\u00ean quan \u0111\u1ebfn ch\u1ebf ph\u1ea9m h\u00e0 th\u1ee7 \u00f4, c\u1ea3 d\u1ea1ng s\u1ed1ng v\u00e0 \u0111\u00e3 ch\u1ebf bi\u1ebfn; m\u1ed9t s\u1ed1 c\u01a1 quan qu\u1ea3n l\u00fd \u0111\u00e3 ph\u00e1t c\u1ea3nh b\u00e1o. Kh\u00f4ng d\u00f9ng k\u00e9o d\u00e0i, li\u1ec1u cao; ng\u01b0\u1eddi c\u00f3 b\u1ec7nh gan kh\u00f4ng n\u00ean d\u00f9ng.<\/li>\n<li>Anthraquinon c\u00f3 t\u00e1c d\u1ee5ng nhu\u1eadn tr\u00e0ng.<\/li>\n<li>Ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u an to\u00e0n cho ph\u1ee5 n\u1eef mang thai, cho con b\u00fa v\u00e0 tr\u1ebb em; ng\u01b0\u1eddi \u0111ang d\u00f9ng thu\u1ed1c n\u00ean h\u1ecfi \u00fd ki\u1ebfn chuy\u00ean gia y t\u1ebf.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Chi\u1ebft xu\u1ea5t d\u01b0\u1ee3c li\u1ec7u \u0111\u01b0\u1ee3c d\u00f9ng c\u1ea3 trong thu\u1ed1c d\u01b0\u1ee3c li\u1ec7u v\u00e0 trong th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe; s\u1ea3n ph\u1ea9m thu\u1ed9c lo\u1ea1i n\u00e0o th\u00ec theo quy \u0111\u1ecbnh c\u1ee7a lo\u1ea1i \u0111\u00f3 (Lu\u1eadt D\u01b0\u1ee3c ho\u1eb7c Lu\u1eadt An to\u00e0n th\u1ef1c ph\u1ea9m, Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP). Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>B\u1ed9 Y t\u1ebf (2017). D\u01b0\u1ee3c \u0111i\u1ec3n Vi\u1ec7t Nam V, chuy\u00ean lu\u1eadn H\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf (r\u1ec5 c\u1ee7); H\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf \u0111\u00e3 ch\u1ebf bi\u1ebfn<\/li>\n<li>Wikipedia \u2013 Reynoutria multiflora \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Reynoutria_multiflora\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Reynoutria_multiflora<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Chi\u1ebft xu\u1ea5t h\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf (Polygonum multiflorum): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t h\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf l\u00e0 cao chi\u1ebft t\u1eeb r\u1ec5 c\u1ee7 c\u00e2y h\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf (Reynoutria multiflora, t\u00ean c\u0169 Polygonum multiflorum). \u0110\u00e2y l\u00e0 d\u01b0\u1ee3c li\u1ec7u c\u1ea7n \u0111\u1eb7c bi\u1ec7t l\u01b0u \u00fd v\u1ec1 an to\u00e0n v\u1edbi gan, v\u00e0 c\u00f3 s\u1ef1 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2877,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-997","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-ha-thu-o-do.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-ha-thu-o-do-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-ha-thu-o-do-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-ha-thu-o-do-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-ha-thu-o-do-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-ha-thu-o-do.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-ha-thu-o-do.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-ha-thu-o-do-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Chi\u1ebft xu\u1ea5t h\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf (Polygonum multiflorum): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t h\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf l\u00e0 cao chi\u1ebft t\u1eeb r\u1ec5 c\u1ee7 c\u00e2y h\u00e0 th\u1ee7 \u00f4 \u0111\u1ecf (Reynoutria multiflora, t\u00ean c\u0169 Polygonum multiflorum). \u0110\u00e2y l\u00e0 d\u01b0\u1ee3c li\u1ec7u c\u1ea7n \u0111\u1eb7c bi\u1ec7t l\u01b0u \u00fd v\u1ec1 an to\u00e0n v\u1edbi gan, v\u00e0 c\u00f3 s\u1ef1&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/997","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=997"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/997\/revisions"}],"predecessor-version":[{"id":3009,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/997\/revisions\/3009"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2877"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=997"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=997"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=997"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}