{"id":990,"date":"2025-05-29T09:45:14","date_gmt":"2025-05-29T09:45:14","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-chiet-xuat-cu-tam-that-gerbex-notogingseng-dang-long\/"},"modified":"2026-09-29T19:20:06","modified_gmt":"2026-09-29T12:20:06","slug":"nguyen-lieu-chiet-xuat-cu-tam-that-gerbex-notogingseng-dang-long","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-chiet-xuat-cu-tam-that-gerbex-notogingseng-dang-long\/","title":{"rendered":"Chi\u1ebft xu\u1ea5t tam th\u1ea5t (Panax notoginseng): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Chi\u1ebft xu\u1ea5t tam th\u1ea5t (Panax notoginseng): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng<\/h1>\n<p><strong>Chi\u1ebft xu\u1ea5t tam th\u1ea5t<\/strong> l\u00e0 cao chi\u1ebft t\u1eeb r\u1ec5 c\u1ee7 c\u00e2y tam th\u1ea5t (<em>Panax notoginseng<\/em>), c\u00f9ng chi v\u1edbi <a href=\"https:\/\/cpc1.vn\/en\/nguyen-lieu-chiet-xuat-nhan-sam-ginseng-extract-5-jiahe\/\">nh\u00e2n s\u00e2m<\/a>. Ch\u1ea5t \u0111\u00e1nh d\u1ea5u l\u00e0 <strong>notoginsenosid R1<\/strong> (\u0111\u1eb7c tr\u01b0ng c\u1ee7a lo\u00e0i) c\u00f9ng ginsenosid Rg1 v\u00e0 Rb1. H\u1ed7n h\u1ee3p saponin tinh ch\u1ebf c\u1ee7a tam th\u1ea5t th\u01b0\u1eddng \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 PNS (<em>Panax notoginseng<\/em> saponins).<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Tam th\u1ea5t, s\u00e2m tam th\u1ea5t, kim b\u1ea5t ho\u00e1n, \u0111i\u1ec1n th\u1ea5t; Notoginseng radix<\/td>\n<\/tr>\n<tr>\n<td>Lo\u00e0i<\/td>\n<td><em>Panax notoginseng (Burkill) F.H.Chen<\/em>, h\u1ecd Nh\u00e2n s\u00e2m (Araliaceae)<\/td>\n<\/tr>\n<tr>\n<td>B\u1ed9 ph\u1eadn d\u00f9ng<\/td>\n<td>R\u1ec5 c\u1ee7<\/td>\n<\/tr>\n<tr>\n<td>Chuy\u00ean lu\u1eadn<\/td>\n<td>D\u01b0\u1ee3c \u0111i\u1ec3n Vi\u1ec7t Nam V: Tam th\u1ea5t (r\u1ec5 c\u1ee7)<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ho\u1ea1t ch\u1ea5t ch\u00ednh<\/td>\n<td>Saponin dammaran: notoginsenosid R1, ginsenosid Rg1, Rb1 (v\u00e0 Re, Rd)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u00e2y v\u00e0 d\u01b0\u1ee3c li\u1ec7u<\/h2>\n<p>Tam th\u1ea5t l\u00e0 c\u00e2y th\u1ea3o s\u1ed1ng l\u00e2u n\u0103m, tr\u1ed3ng d\u01b0\u1edbi gi\u00e0n che \u1edf v\u00f9ng n\u00fai cao (V\u00e2n Nam \u2013 Trung Qu\u1ed1c; H\u00e0 Giang, L\u00e0o Cai \u1edf Vi\u1ec7t Nam). R\u1ec5 c\u1ee7 \u0111\u01b0\u1ee3c thu ho\u1ea1ch sau 3 n\u0103m tr\u1edf l\u00ean. T\u00ean &#8220;tam th\u1ea5t&#8221; \u0111\u01b0\u1ee3c gi\u1ea3i th\u00edch l\u00e0 c\u00e2y c\u00f3 ba cu\u1ed1ng l\u00e1, m\u1ed7i cu\u1ed1ng b\u1ea3y l\u00e1 ch\u00e9t, ho\u1eb7c c\u1ea7n 3\u20137 n\u0103m m\u1edbi thu ho\u1ea1ch.<\/p>\n<h2>Th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc<\/h2>\n<ul>\n<li><strong>Saponin dammaran<\/strong>: notoginsenosid R1, ginsenosid Rg1, Rb1 l\u00e0 ba th\u00e0nh ph\u1ea7n ch\u00ednh; ngo\u00e0i ra Re, Rd v\u00e0 nhi\u1ec1u saponin kh\u00e1c.<\/li>\n<li>Dencichin (acid amin kh\u00f4ng c\u1ea5u t\u1ea1o protein), polysaccharid, flavonoid.<\/li>\n<\/ul>\n<h2>Chi\u1ebft xu\u1ea5t v\u00e0 ti\u00eau chu\u1ea9n h\u00f3a<\/h2>\n<p>R\u1ec5 c\u1ee7 \u0111\u01b0\u1ee3c chi\u1ebft b\u1eb1ng ethanol \u2013 n\u01b0\u1edbc, tinh ch\u1ebf qua nh\u1ef1a h\u1ea5p ph\u1ee5 v\u00e0 s\u1ea5y; nguy\u00ean li\u1ec7u ti\u00eau chu\u1ea9n h\u00f3a theo t\u1ed5ng saponin (v\u00ed d\u1ee5 80% PNS) ho\u1eb7c theo t\u1ed5ng R1 + Rg1 + Rb1 (HPLC). Chi\u1ebft xu\u1ea5t d\u1ea1ng l\u1ecfng trong glycol d\u00f9ng cho m\u1ef9 ph\u1ea9m.<\/p>\n<h2>Ch\u1ec9 ti\u00eau ch\u1ea5t l\u01b0\u1ee3ng n\u00ean xem<\/h2>\n<ul>\n<li>Notoginsenosid R1, ginsenosid Rg1, Rb1 (HPLC); t\u1ef7 l\u1ec7 c\u00e1c ch\u1ea5t \u0111\u1ec3 x\u00e1c nh\u1eadn lo\u00e0i.<\/li>\n<li>Tam th\u1ea5t tr\u1ed3ng nhi\u1ec1u n\u0103m: \u0111\u1eb7c bi\u1ec7t ch\u00fa \u00fd d\u01b0 l\u01b0\u1ee3ng thu\u1ed1c b\u1ea3o v\u1ec7 th\u1ef1c v\u1eadt v\u00e0 kim lo\u1ea1i n\u1eb7ng (arsen, cadimi).<\/li>\n<li>Kim lo\u1ea1i n\u1eb7ng, vi sinh v\u1eadt, d\u01b0 l\u01b0\u1ee3ng thu\u1ed1c b\u1ea3o v\u1ec7 th\u1ef1c v\u1eadt; \u0111\u1ed9c t\u1ed1 vi n\u1ea5m v\u1edbi d\u01b0\u1ee3c li\u1ec7u d\u1ec5 m\u1ed1c.<\/li>\n<\/ul>\n<h2>Applications<\/h2>\n<ul>\n<li>Thu\u1ed1c d\u01b0\u1ee3c li\u1ec7u, th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe.<\/li>\n<li>M\u1ef9 ph\u1ea9m.<\/li>\n<li>C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n<h2>An to\u00e0n v\u00e0 l\u01b0u \u00fd<\/h2>\n<ul>\n<li>Theo \u0110\u00f4ng y, kh\u00f4ng d\u00f9ng cho ph\u1ee5 n\u1eef mang thai.<\/li>\n<li>C\u00f3 th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng, ch\u1ed1ng k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u.<\/li>\n<li>Ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u an to\u00e0n cho ph\u1ee5 n\u1eef mang thai, cho con b\u00fa v\u00e0 tr\u1ebb em; ng\u01b0\u1eddi \u0111ang d\u00f9ng thu\u1ed1c n\u00ean h\u1ecfi \u00fd ki\u1ebfn chuy\u00ean gia y t\u1ebf.<\/li>\n<\/ul>\n<p><!--my-pham--><\/p>\n<h2>In Cosmetics<\/h2>\n<p>Ngo\u00e0i d\u01b0\u1ee3c ph\u1ea9m v\u00e0 th\u1ef1c ph\u1ea9m, nguy\u00ean li\u1ec7u t\u1eeb lo\u00e0i n\u00e0y c\u00f2n \u0111\u01b0\u1ee3c d\u00f9ng trong m\u1ef9 ph\u1ea9m d\u01b0\u1edbi c\u00e1c t\u00ean INCI sau (ch\u1ee9c n\u0103ng theo c\u01a1 s\u1edf d\u1eef li\u1ec7u CosIng c\u1ee7a \u1ee6y ban ch\u00e2u \u00c2u):<\/p>\n<table>\n<thead>\n<tr>\n<th>T\u00ean INCI<\/th>\n<th>D\u1ea1ng nguy\u00ean li\u1ec7u<\/th>\n<th>Ch\u1ee9c n\u0103ng (CosIng)<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Panax Notoginseng Root Extract<\/td>\n<td>cao chi\u1ebft b\u1eb1ng dung m\u00f4i (th\u01b0\u1eddng l\u00e0 n\u01b0\u1edbc, glycol ho\u1eb7c ethanol), sau \u0111\u00f3 pha lo\u00e3ng trong dung m\u00f4i mang<\/td>\n<td>gi\u1eef \u1ea9m<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Theo CosIng, c\u00e1c t\u00ean INCI tr\u00ean kh\u00f4ng thu\u1ed9c ph\u1ee5 l\u1ee5c ch\u1ea5t c\u1ea5m (Annex II) hay h\u1ea1n ch\u1ebf (Annex III) c\u1ee7a EU t\u1ea1i th\u1eddi \u0111i\u1ec3m vi\u1ebft b\u00e0i; ph\u1ee5 l\u1ee5c c\u1ee7a Hi\u1ec7p \u0111\u1ecbnh m\u1ef9 ph\u1ea9m ASEAN \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadt theo danh m\u1ee5c n\u00e0y. T\u1ea1i Vi\u1ec7t Nam, m\u1ef9 ph\u1ea9m qu\u1ea3n l\u00fd theo Th\u00f4ng t\u01b0 06\/2011\/TT-BYT; t\u00ednh n\u0103ng c\u00f4ng b\u1ed1 ph\u1ea3i theo H\u01b0\u1edbng d\u1eabn c\u00f4ng b\u1ed1 t\u00ednh n\u0103ng m\u1ef9 ph\u1ea9m ASEAN, kh\u00f4ng \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 c\u00f4ng d\u1ee5ng nh\u01b0 thu\u1ed1c.<\/p>\n<p><!--\/my-pham--><\/p>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Chi\u1ebft xu\u1ea5t d\u01b0\u1ee3c li\u1ec7u \u0111\u01b0\u1ee3c d\u00f9ng c\u1ea3 trong thu\u1ed1c d\u01b0\u1ee3c li\u1ec7u v\u00e0 trong th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe; s\u1ea3n ph\u1ea9m thu\u1ed9c lo\u1ea1i n\u00e0o th\u00ec theo quy \u0111\u1ecbnh c\u1ee7a lo\u1ea1i \u0111\u00f3 (Lu\u1eadt D\u01b0\u1ee3c ho\u1eb7c Lu\u1eadt An to\u00e0n th\u1ef1c ph\u1ea9m, Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP). Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>B\u1ed9 Y t\u1ebf (2017). D\u01b0\u1ee3c \u0111i\u1ec3n Vi\u1ec7t Nam V, chuy\u00ean lu\u1eadn Tam th\u1ea5t (r\u1ec5 c\u1ee7)<\/li>\n<li>Wikipedia \u2013 Panax notoginseng \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Panax_notoginseng\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Panax_notoginseng<\/a><\/li>\n<li>Wikipedia \u2013 Ginsenoside \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Ginsenoside\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Ginsenoside<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Chi\u1ebft xu\u1ea5t tam th\u1ea5t (Panax notoginseng): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t tam th\u1ea5t l\u00e0 cao chi\u1ebft t\u1eeb r\u1ec5 c\u1ee7 c\u00e2y tam th\u1ea5t (Panax notoginseng), c\u00f9ng chi v\u1edbi nh\u00e2n s\u00e2m. Ch\u1ea5t \u0111\u00e1nh d\u1ea5u l\u00e0 notoginsenosid R1 (\u0111\u1eb7c tr\u01b0ng c\u1ee7a lo\u00e0i) c\u00f9ng ginsenosid Rg1 v\u00e0 Rb1. H\u1ed7n h\u1ee3p saponin tinh ch\u1ebf c\u1ee7a tam [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1987,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-990","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/panax-notoginseng-cay-nguyen-lieu.jpg",1200,900,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/panax-notoginseng-cay-nguyen-lieu-150x150.jpg",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/panax-notoginseng-cay-nguyen-lieu-300x225.jpg",300,225,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/panax-notoginseng-cay-nguyen-lieu-768x576.jpg",768,576,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/panax-notoginseng-cay-nguyen-lieu-1024x768.jpg",1024,768,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/panax-notoginseng-cay-nguyen-lieu.jpg",1200,900,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/panax-notoginseng-cay-nguyen-lieu.jpg",1200,900,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/panax-notoginseng-cay-nguyen-lieu-16x12.jpg",16,12,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":1,"uagb_excerpt":"Chi\u1ebft xu\u1ea5t tam th\u1ea5t (Panax notoginseng): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t tam th\u1ea5t l\u00e0 cao chi\u1ebft t\u1eeb r\u1ec5 c\u1ee7 c\u00e2y tam th\u1ea5t (Panax notoginseng), c\u00f9ng chi v\u1edbi nh\u00e2n s\u00e2m. Ch\u1ea5t \u0111\u00e1nh d\u1ea5u l\u00e0 notoginsenosid R1 (\u0111\u1eb7c tr\u01b0ng c\u1ee7a lo\u00e0i) c\u00f9ng ginsenosid Rg1 v\u00e0 Rb1. H\u1ed7n h\u1ee3p saponin tinh ch\u1ebf c\u1ee7a tam&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/990","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=990"}],"version-history":[{"count":3,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/990\/revisions"}],"predecessor-version":[{"id":4097,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/990\/revisions\/4097"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/1987"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=990"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=990"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=990"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}