{"id":976,"date":"2025-05-29T09:38:10","date_gmt":"2025-05-29T09:38:10","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-chiet-xuat-cay-trinh-nu-chaste-tree-berries-dry-ex\/"},"modified":"2026-09-30T15:27:39","modified_gmt":"2026-09-30T08:27:39","slug":"nguyen-lieu-chiet-xuat-cay-trinh-nu-chaste-tree-berries-dry-ex","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-chiet-xuat-cay-trinh-nu-chaste-tree-berries-dry-ex\/","title":{"rendered":"Chi\u1ebft xu\u1ea5t qu\u1ea3 trinh n\u1eef (Vitex agnus-castus): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Chi\u1ebft xu\u1ea5t qu\u1ea3 trinh n\u1eef (Vitex agnus-castus): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng<\/h1>\n<p><strong>Chi\u1ebft xu\u1ea5t qu\u1ea3 trinh n\u1eef<\/strong> (chasteberry) l\u00e0 cao chi\u1ebft t\u1eeb qu\u1ea3 ch\u00edn c\u1ee7a c\u00e2y <em>Vitex agnus-castus<\/em>, c\u00e2y b\u1ee5i v\u00f9ng \u0110\u1ecba Trung H\u1ea3i. C\u1ea7n ph\u00e2n bi\u1ec7t v\u1edbi c\u00e2y &#8220;trinh n\u1eef&#8221; (x\u1ea5u h\u1ed5, <em>Mimosa pudica<\/em>) v\u00e0 <a href=\"https:\/\/cpc1.vn\/en\/nguyen-lieu-chiet-xuat-trinh-nu-hoang-cung-crinum-latifolium-extract\/\">trinh n\u1eef ho\u00e0ng cung<\/a> (<em>Crinum latifolium<\/em>) \u1edf Vi\u1ec7t Nam: \u0111\u00e2y l\u00e0 ba lo\u00e0i ho\u00e0n to\u00e0n kh\u00e1c nhau.<\/p>\n<figure class=\"wp-block-image size-large cpc1-anh-cay\"><img decoding=\"async\" src=\"https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitex-agnus-castus-cay-nguyen-lieu.jpg\" alt=\"C\u00e2y trinh n\u1eef \u2013 Vitex agnus-castus, ngu\u1ed3n nguy\u00ean li\u1ec7u chi\u1ebft xu\u1ea5t\"\/><figcaption>Trinh n\u1eef (<em>Vitex agnus-castus<\/em>). \u1ea2nh: Almapayokels, <a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Vitex_Agnus_Castus.jpg\" rel=\"nofollow noopener\" target=\"_blank\">Wikimedia Commons<\/a>, gi\u1ea5y ph\u00e9p <a href=\"https:\/\/creativecommons.org\/publicdomain\/zero\/1.0\/\" rel=\"nofollow noopener\" target=\"_blank\">CC0<\/a>.<\/figcaption><\/figure>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Chasteberry, chaste tree, monk&#8217;s pepper, qu\u1ea3 trinh n\u1eef ch\u00e2u \u00c2u; Agni casti fructus<\/td>\n<\/tr>\n<tr>\n<td>Lo\u00e0i<\/td>\n<td><em>Vitex agnus-castus L.<\/em>, h\u1ecd Hoa m\u00f4i (Lamiaceae)<\/td>\n<\/tr>\n<tr>\n<td>B\u1ed9 ph\u1eadn d\u00f9ng<\/td>\n<td>Qu\u1ea3 ch\u00edn<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ho\u1ea1t ch\u1ea5t ch\u00ednh<\/td>\n<td>Diterpen (rotundifuran\u2026), flavonoid (casticin, vitexin), iridoid glycosid (agnusid, aucubin)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u00e2y v\u00e0 d\u01b0\u1ee3c li\u1ec7u<\/h2>\n<p><em>Vitex agnus-castus<\/em> l\u00e0 c\u00e2y b\u1ee5i cao 1\u20135 m, l\u00e1 k\u00e9p ch\u00e2n v\u1ecbt, hoa m\u00e0u t\u00edm nh\u1ea1t th\u00e0nh ch\u00f9m. Qu\u1ea3 nh\u1ecf nh\u01b0 h\u1ea1t ti\u00eau, c\u00f3 v\u1ecb cay, n\u00ean c\u00f2n \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 &#8220;ti\u00eau th\u1ea7y tu&#8221; (monk&#8217;s pepper).<\/p>\n<h2>Th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc<\/h2>\n<ul>\n<li><strong>Flavonoid<\/strong>: casticin (th\u01b0\u1eddng d\u00f9ng l\u00e0m ch\u1ea5t \u0111\u00e1nh d\u1ea5u), vitexin, orientin.<\/li>\n<li><strong>Iridoid glycosid<\/strong>: agnusid, aucubin.<\/li>\n<li>Diterpen labdan, tinh d\u1ea7u.<\/li>\n<\/ul>\n<h2>Chi\u1ebft xu\u1ea5t v\u00e0 ti\u00eau chu\u1ea9n h\u00f3a<\/h2>\n<p>Qu\u1ea3 kh\u00f4 \u0111\u01b0\u1ee3c chi\u1ebft b\u1eb1ng ethanol \u2013 n\u01b0\u1edbc (v\u00ed d\u1ee5 60\u201370%), c\u00f4 \u0111\u1eb7c v\u00e0 s\u1ea5y th\u00e0nh cao kh\u00f4. Nguy\u00ean li\u1ec7u th\u01b0\u1eddng ghi t\u1ef7 l\u1ec7 d\u01b0\u1ee3c li\u1ec7u\/cao (v\u00ed d\u1ee5 4:1, 10:1) v\u00e0\/ho\u1eb7c h\u00e0m l\u01b0\u1ee3ng <strong>casticin<\/strong>, agnusid.<\/p>\n<h2>Ch\u1ec9 ti\u00eau ch\u1ea5t l\u01b0\u1ee3ng n\u00ean xem<\/h2>\n<ul>\n<li>Casticin, agnusid (HPLC); t\u1ef7 l\u1ec7 d\u01b0\u1ee3c li\u1ec7u\/cao.<\/li>\n<li>Kim lo\u1ea1i n\u1eb7ng, vi sinh, \u0111\u1ed9c t\u1ed1 vi n\u1ea5m.<\/li>\n<\/ul>\n<h2>Applications<\/h2>\n<ul>\n<li>Thu\u1ed1c d\u01b0\u1ee3c li\u1ec7u (EU c\u00f3 chuy\u00ean lu\u1eadn Agni casti fructus).<\/li>\n<li>Th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe.<\/li>\n<li>C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n<h2>An to\u00e0n v\u00e0 l\u01b0u \u00fd<\/h2>\n<ul>\n<li>C\u00f3 th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi thu\u1ed1c t\u00e1c \u0111\u1ed9ng l\u00ean h\u1ec7 dopamin v\u00e0 thu\u1ed1c tr\u00e1nh thai n\u1ed9i ti\u1ebft; kh\u00f4ng d\u00f9ng khi mang thai, cho con b\u00fa (theo chuy\u00ean lu\u1eadn EMA).<\/li>\n<li>Kh\u00f4ng khuy\u1ebfn c\u00e1o cho tr\u1ebb d\u01b0\u1edbi 18 tu\u1ed5i.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Chi\u1ebft xu\u1ea5t d\u01b0\u1ee3c li\u1ec7u \u0111\u01b0\u1ee3c d\u00f9ng c\u1ea3 trong thu\u1ed1c d\u01b0\u1ee3c li\u1ec7u v\u00e0 trong th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe; s\u1ea3n ph\u1ea9m thu\u1ed9c lo\u1ea1i n\u00e0o th\u00ec theo quy \u0111\u1ecbnh c\u1ee7a lo\u1ea1i \u0111\u00f3 (Lu\u1eadt D\u01b0\u1ee3c ho\u1eb7c Lu\u1eadt An to\u00e0n th\u1ef1c ph\u1ea9m, Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP). Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>EMA \u2013 Agni casti fructus (chuy\u00ean lu\u1eadn d\u01b0\u1ee3c li\u1ec7u EU) \u2014 <a href=\"https:\/\/www.ema.europa.eu\/en\/medicines\/herbal\/agni-casti-fructus\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.ema.europa.eu\/en\/medicines\/herbal\/agni-casti-fructus<\/a><\/li>\n<li>Wikipedia \u2013 Vitex agnus-castus \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Vitex_agnus-castus\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Vitex_agnus-castus<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Chi\u1ebft xu\u1ea5t qu\u1ea3 trinh n\u1eef (Vitex agnus-castus): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t qu\u1ea3 trinh n\u1eef (chasteberry) l\u00e0 cao chi\u1ebft t\u1eeb qu\u1ea3 ch\u00edn c\u1ee7a c\u00e2y Vitex agnus-castus, c\u00e2y b\u1ee5i v\u00f9ng \u0110\u1ecba Trung H\u1ea3i. C\u1ea7n ph\u00e2n bi\u1ec7t v\u1edbi c\u00e2y &#8220;trinh n\u1eef&#8221; (x\u1ea5u h\u1ed5, Mimosa pudica) v\u00e0 trinh n\u1eef ho\u00e0ng cung (Crinum latifolium) \u1edf [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1988,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-976","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitex-agnus-castus-cay-nguyen-lieu.jpg",1200,900,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitex-agnus-castus-cay-nguyen-lieu-150x150.jpg",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitex-agnus-castus-cay-nguyen-lieu-300x225.jpg",300,225,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitex-agnus-castus-cay-nguyen-lieu-768x576.jpg",768,576,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitex-agnus-castus-cay-nguyen-lieu-1024x768.jpg",1024,768,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitex-agnus-castus-cay-nguyen-lieu.jpg",1200,900,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitex-agnus-castus-cay-nguyen-lieu.jpg",1200,900,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitex-agnus-castus-cay-nguyen-lieu-16x12.jpg",16,12,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":1,"uagb_excerpt":"Chi\u1ebft xu\u1ea5t qu\u1ea3 trinh n\u1eef (Vitex agnus-castus): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t qu\u1ea3 trinh n\u1eef (chasteberry) l\u00e0 cao chi\u1ebft t\u1eeb qu\u1ea3 ch\u00edn c\u1ee7a c\u00e2y Vitex agnus-castus, c\u00e2y b\u1ee5i v\u00f9ng \u0110\u1ecba Trung H\u1ea3i. C\u1ea7n ph\u00e2n bi\u1ec7t v\u1edbi c\u00e2y &#8220;trinh n\u1eef&#8221; (x\u1ea5u h\u1ed5, Mimosa pudica) v\u00e0 trinh n\u1eef ho\u00e0ng cung (Crinum latifolium) \u1edf&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/976","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=976"}],"version-history":[{"count":4,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/976\/revisions"}],"predecessor-version":[{"id":5102,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/976\/revisions\/5102"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/1988"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=976"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=976"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=976"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}