{"id":902,"date":"2025-05-29T09:01:12","date_gmt":"2025-05-29T09:01:12","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-chiet-xuat-co-ngot-stevia-extract-powder\/"},"modified":"2026-09-28T22:19:37","modified_gmt":"2026-09-28T15:19:37","slug":"nguyen-lieu-chiet-xuat-co-ngot-stevia-extract-powder","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-chiet-xuat-co-ngot-stevia-extract-powder\/","title":{"rendered":"Chi\u1ebft xu\u1ea5t c\u1ecf ng\u1ecdt (steviol glycosid, INS 960): th\u00e0nh ph\u1ea7n, ph\u00e2n lo\u1ea1i v\u00e0 quy \u0111\u1ecbnh"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Chi\u1ebft xu\u1ea5t c\u1ecf ng\u1ecdt (steviol glycosid, INS 960): th\u00e0nh ph\u1ea7n, ph\u00e2n lo\u1ea1i v\u00e0 quy \u0111\u1ecbnh<\/h1>\n<p><strong>Chi\u1ebft xu\u1ea5t c\u1ecf ng\u1ecdt<\/strong> l\u00e0 nguy\u00ean li\u1ec7u t\u1ea1o ng\u1ecdt t\u1eeb l\u00e1 c\u00e2y c\u1ecf ng\u1ecdt (<em>Stevia rebaudiana<\/em>), c\u00e2y g\u1ed1c Paraguay. Ho\u1ea1t ch\u1ea5t t\u1ea1o ng\u1ecdt l\u00e0 nh\u00f3m <strong>steviol glycosid<\/strong>, ng\u1ecdt h\u01a1n \u0111\u01b0\u1eddng sucrose kho\u1ea3ng 200\u2013300 l\u1ea7n. C\u00f3 hai lo\u1ea1i nguy\u00ean li\u1ec7u kh\u00e1c nhau: <strong>chi\u1ebft xu\u1ea5t l\u00e1 th\u00f4<\/strong> v\u00e0 <strong>steviol glycosid tinh ch\u1ebf<\/strong> (ph\u1ee5 gia t\u1ea1o ng\u1ecdt INS 960).<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>C\u1ecf ng\u1ecdt, c\u1ecf m\u1eadt, stevia; steviol glycosid (INS 960)<\/td>\n<\/tr>\n<tr>\n<td>Lo\u00e0i<\/td>\n<td><em>Stevia rebaudiana (Bertoni) Bertoni<\/em>, h\u1ecd C\u00fac (Asteraceae)<\/td>\n<\/tr>\n<tr>\n<td>B\u1ed9 ph\u1eadn d\u00f9ng<\/td>\n<td>L\u00e1<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ho\u1ea1t ch\u1ea5t ch\u00ednh<\/td>\n<td>Steviol glycosid: steviosid, rebaudiosid A (v\u00e0 D, M, C\u2026)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u00e2y v\u00e0 d\u01b0\u1ee3c li\u1ec7u<\/h2>\n<p>C\u1ecf ng\u1ecdt l\u00e0 c\u00e2y th\u1ea3o s\u1ed1ng l\u00e2u n\u0103m, l\u00e1 m\u1ecdc \u0111\u1ed1i c\u00f3 r\u0103ng c\u01b0a, nhai l\u00e1 th\u1ea5y v\u1ecb ng\u1ecdt \u0111\u1eadm. C\u00e2y \u0111\u01b0\u1ee3c tr\u1ed3ng nhi\u1ec1u \u1edf Trung Qu\u1ed1c, Paraguay v\u00e0 c\u1ea3 Vi\u1ec7t Nam (\u0110\u00e0 L\u1ea1t, H\u00e0 Giang&#8230;).<\/p>\n<h2>Th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc<\/h2>\n<ul>\n<li><strong>Steviol glycosid<\/strong>: stevioside v\u00e0 rebaudiosid A l\u00e0 hai ch\u1ea5t ch\u00ednh; rebaudiosid D, M \u00edt \u0111\u1eafng h\u1eadu v\u1ecb h\u01a1n nh\u01b0ng h\u00e0m l\u01b0\u1ee3ng t\u1ef1 nhi\u00ean th\u1ea5p.<\/li>\n<li>Flavonoid, acid phenolic, diterpen kh\u00e1c (\u1edf chi\u1ebft xu\u1ea5t th\u00f4).<\/li>\n<\/ul>\n<h2>Chi\u1ebft xu\u1ea5t v\u00e0 ti\u00eau chu\u1ea9n h\u00f3a<\/h2>\n<p><strong>Steviol glycosid tinh ch\u1ebf<\/strong>: l\u00e1 \u0111\u01b0\u1ee3c chi\u1ebft b\u1eb1ng n\u01b0\u1edbc n\u00f3ng, tinh ch\u1ebf qua nh\u1ef1a h\u1ea5p ph\u1ee5 v\u00e0 k\u1ebft tinh b\u1eb1ng ethanol, cho \u0111\u1ed9 tinh khi\u1ebft t\u1eeb 95% steviol glycosid tr\u1edf l\u00ean (v\u00ed d\u1ee5 Reb A 97%). <strong>Chi\u1ebft xu\u1ea5t l\u00e1 th\u00f4<\/strong> (cao n\u01b0\u1edbc, b\u1ed9t l\u00e1) c\u00f3 \u0111\u1ed9 tinh khi\u1ebft th\u1ea5p, v\u1ecb c\u1ecf r\u00f5 h\u01a1n. Rebaudiosid M, D c\u00f2n \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1eb1ng l\u00ean men ho\u1eb7c chuy\u1ec3n h\u00f3a enzym t\u1eeb c\u00e1c glycosid kh\u00e1c.<\/p>\n<h2>Ch\u1ec9 ti\u00eau ch\u1ea5t l\u01b0\u1ee3ng n\u00ean xem<\/h2>\n<ul>\n<li>T\u1ed5ng steviol glycosid v\u00e0 t\u1eebng glycosid (HPLC theo JECFA); dung m\u00f4i t\u1ed3n d\u01b0 (ethanol, methanol).<\/li>\n<li>Kim lo\u1ea1i n\u1eb7ng, vi sinh v\u1eadt, d\u01b0 l\u01b0\u1ee3ng thu\u1ed1c b\u1ea3o v\u1ec7 th\u1ef1c v\u1eadt; \u0111\u1ed9c t\u1ed1 vi n\u1ea5m v\u1edbi d\u01b0\u1ee3c li\u1ec7u d\u1ec5 m\u1ed1c.<\/li>\n<\/ul>\n<h2>Applications<\/h2>\n<ul>\n<li>Ch\u1ea5t t\u1ea1o ng\u1ecdt kh\u00f4ng n\u0103ng l\u01b0\u1ee3ng trong \u0111\u1ed3 u\u1ed1ng, th\u1ef1c ph\u1ea9m, th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe; th\u01b0\u1eddng ph\u1ed1i h\u1ee3p v\u1edbi <a href=\"\/en\/erythritol\/\">erythritol<\/a>.<\/li>\n<li>C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n<h2>An to\u00e0n v\u00e0 l\u01b0u \u00fd<\/h2>\n<ul>\n<li><strong>JECFA<\/strong> \u0111\u1eb7t ADI 0\u20134 mg\/kg th\u1ec3 tr\u1ecdng t\u00ednh theo steviol.<\/li>\n<li>T\u1ea1i nhi\u1ec1u th\u1ecb tr\u01b0\u1eddng, ch\u1ec9 <strong>steviol glycosid tinh ch\u1ebf<\/strong> \u0111\u1ea1t ti\u00eau chu\u1ea9n ph\u1ee5 gia m\u1edbi \u0111\u01b0\u1ee3c d\u00f9ng nh\u01b0 ch\u1ea5t t\u1ea1o ng\u1ecdt; l\u00e1 v\u00e0 chi\u1ebft xu\u1ea5t th\u00f4 c\u00f3 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd kh\u00e1c (v\u00ed d\u1ee5 \u1edf EU, M\u1ef9). Ng\u01b0\u1eddi d\u1ecb \u1ee9ng c\u00e2y h\u1ecd C\u00fac c\u00f3 th\u1ec3 d\u1ecb \u1ee9ng.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Steviol glycosid l\u00e0 ph\u1ee5 gia t\u1ea1o ng\u1ecdt theo danh m\u1ee5c c\u1ee7a B\u1ed9 Y t\u1ebf (Th\u00f4ng t\u01b0 24\/2019\/TT-BYT); vi\u1ec7c d\u00f9ng ph\u1ea3i theo \u0111\u00fang m\u00e3 ph\u1ee5 gia, nh\u00f3m th\u1ef1c ph\u1ea9m v\u00e0 m\u1ee9c t\u1ed1i \u0111a trong danh m\u1ee5c. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Stevia rebaudiana \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Stevia_rebaudiana\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Stevia_rebaudiana<\/a><\/li>\n<li>Wikipedia \u2013 Steviol glycoside \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Steviol_glycoside\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Steviol_glycoside<\/a><\/li>\n<li>JECFA (FAO\/WHO) \u2013 c\u01a1 s\u1edf d\u1eef li\u1ec7u \u0111\u00e1nh gi\u00e1 ph\u1ee5 gia th\u1ef1c ph\u1ea9m \u2014 <a href=\"https:\/\/apps.who.int\/food-additives-contaminants-jecfa-database\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/apps.who.int\/food-additives-contaminants-jecfa-database\/<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Chi\u1ebft xu\u1ea5t c\u1ecf ng\u1ecdt (steviol glycosid, INS 960): th\u00e0nh ph\u1ea7n, ph\u00e2n lo\u1ea1i v\u00e0 quy \u0111\u1ecbnh Chi\u1ebft xu\u1ea5t c\u1ecf ng\u1ecdt l\u00e0 nguy\u00ean li\u1ec7u t\u1ea1o ng\u1ecdt t\u1eeb l\u00e1 c\u00e2y c\u1ecf ng\u1ecdt (Stevia rebaudiana), c\u00e2y g\u1ed1c Paraguay. Ho\u1ea1t ch\u1ea5t t\u1ea1o ng\u1ecdt l\u00e0 nh\u00f3m steviol glycosid, ng\u1ecdt h\u01a1n \u0111\u01b0\u1eddng sucrose kho\u1ea3ng 200\u2013300 l\u1ea7n. C\u00f3 hai lo\u1ea1i nguy\u00ean li\u1ec7u kh\u00e1c [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3446,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-902","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-co-ngot.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-co-ngot-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-co-ngot-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-co-ngot-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-co-ngot-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-co-ngot.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-co-ngot.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-co-ngot-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Chi\u1ebft xu\u1ea5t c\u1ecf ng\u1ecdt (steviol glycosid, INS 960): th\u00e0nh ph\u1ea7n, ph\u00e2n lo\u1ea1i v\u00e0 quy \u0111\u1ecbnh Chi\u1ebft xu\u1ea5t c\u1ecf ng\u1ecdt l\u00e0 nguy\u00ean li\u1ec7u t\u1ea1o ng\u1ecdt t\u1eeb l\u00e1 c\u00e2y c\u1ecf ng\u1ecdt (Stevia rebaudiana), c\u00e2y g\u1ed1c Paraguay. Ho\u1ea1t ch\u1ea5t t\u1ea1o ng\u1ecdt l\u00e0 nh\u00f3m steviol glycosid, ng\u1ecdt h\u01a1n \u0111\u01b0\u1eddng sucrose kho\u1ea3ng 200\u2013300 l\u1ea7n. C\u00f3 hai lo\u1ea1i nguy\u00ean li\u1ec7u kh\u00e1c&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/902","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=902"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/902\/revisions"}],"predecessor-version":[{"id":1187,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/902\/revisions\/1187"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3446"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=902"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=902"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=902"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}