{"id":885,"date":"2025-05-29T08:52:57","date_gmt":"2025-05-29T08:52:57","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-piroctone-olamine\/"},"modified":"2026-09-29T11:49:35","modified_gmt":"2026-09-29T04:49:35","slug":"nguyen-lieu-piroctone-olamine","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-piroctone-olamine\/","title":{"rendered":"Piroctone olamine: ho\u1ea1t ch\u1ea5t ch\u1ed1ng g\u00e0u \u2013 c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, gi\u1edbi h\u1ea1n"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Piroctone olamine: ho\u1ea1t ch\u1ea5t ch\u1ed1ng g\u00e0u \u2013 c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, gi\u1edbi h\u1ea1n<\/h1>\n<p><strong>Piroctone olamine<\/strong> l\u00e0 ho\u1ea1t ch\u1ea5t ch\u1ed1ng g\u00e0u v\u00e0 ch\u1ea5t b\u1ea3o qu\u1ea3n d\u00f9ng trong m\u1ef9 ph\u1ea9m ch\u0103m s\u00f3c t\u00f3c. \u0110\u00e2y l\u00e0 <strong>mu\u1ed1i ethanolamin<\/strong> (olamin) c\u1ee7a piroctone, m\u1ed9t d\u1eabn ch\u1ea5t <strong>hydroxypyridon<\/strong>. Ch\u1ea5t \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n t\u1ea1i \u0110\u1ee9c v\u00e0o th\u1eadp ni\u00ean 1970 v\u00e0 th\u01b0\u1eddng \u0111\u01b0\u1ee3c bi\u1ebft qua t\u00ean th\u01b0\u01a1ng m\u1ea1i \u0111\u1ea7u ti\u00ean l\u00e0 Octopirox.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Piroctone olamine, piroctone ethanolamin<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c, kh\u1ed1i l\u01b0\u1ee3ng mol<\/td>\n<td>C<sub>16<\/sub>H<sub>30<\/sub>N<sub>2<\/sub>O<sub>3<\/sub> \u2013 298,43 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>68890-66-4<\/td>\n<\/tr>\n<tr>\n<td>T\u00ean INCI<\/td>\n<td>Piroctone Olamine<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u1ea5u t\u1ea1o v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>Ph\u1ea7n ho\u1ea1t t\u00ednh l\u00e0 v\u00f2ng 1-hydroxy-2-pyridon, c\u00f3 kh\u1ea3 n\u0103ng <strong>t\u1ea1o ph\u1ee9c v\u1edbi ion s\u1eaft (Fe<sup>3+<\/sup>)<\/strong>. C\u01a1 ch\u1ebf kh\u00e1ng n\u1ea5m \u0111\u01b0\u1ee3c cho l\u00e0 li\u00ean quan \u0111\u1ebfn vi\u1ec7c l\u1ea5y \u0111i s\u1eaft c\u1ea7n cho chuy\u1ec3n h\u00f3a n\u0103ng l\u01b0\u1ee3ng c\u1ee7a t\u1ebf b\u00e0o n\u1ea5m <em>Malassezia<\/em>.<\/li>\n<li>B\u1ed9t k\u1ebft tinh m\u00e0u tr\u1eafng \u0111\u1ebfn h\u01a1i v\u00e0ng. \u00cdt tan trong n\u01b0\u1edbc, tan trong dung d\u1ecbch ch\u1ea5t di\u1ec7n ho\u1ea1t, ethanol.<\/li>\n<li>V\u00ec t\u1ea1o ph\u1ee9c v\u1edbi kim lo\u1ea1i, dung d\u1ecbch c\u00f3 th\u1ec3 \u0111\u1ed5i m\u00e0u khi g\u1eb7p ion s\u1eaft, \u0111\u1ed3ng. N\u00ean d\u00f9ng ch\u1ea5t t\u1ea1o ph\u1ee9c (nh\u01b0 EDTA) v\u00e0 tr\u00e1nh d\u1ee5ng c\u1ee5, nguy\u00ean li\u1ec7u nhi\u1ec5m kim lo\u1ea1i.<\/li>\n<\/ul>\n<h2>Gi\u1edbi h\u1ea1n s\u1eed d\u1ee5ng t\u1ea1i EU<\/h2>\n<p>Piroctone olamine c\u00f3 trong Ph\u1ee5 l\u1ee5c V (ch\u1ea5t b\u1ea3o qu\u1ea3n) c\u1ee7a Quy \u0111\u1ecbnh (EC) 1223\/2009: t\u1ed1i \u0111a <strong>1,0%<\/strong> trong s\u1ea3n ph\u1ea9m x\u1ea3 s\u1ea1ch v\u00e0 <strong>0,5%<\/strong> trong c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c. L\u00e0 alkanolamin, ch\u1ea5t c\u0169ng ph\u1ea3i tu\u00e2n th\u1ee7 gi\u1edbi h\u1ea1n nitrosamin theo Ph\u1ee5 l\u1ee5c III.<\/p>\n<h2>Applications<\/h2>\n<ul>\n<li>D\u1ea7u g\u1ed9i, d\u1ea7u x\u1ea3, tinh ch\u1ea5t da \u0111\u1ea7u ch\u1ed1ng g\u00e0u; th\u01b0\u1eddng thay th\u1ebf ho\u1eb7c ph\u1ed1i h\u1ee3p v\u1edbi k\u1ebdm pyrithion, <a href=\"https:\/\/cpc1.vn\/en\/nguyen-lieu-climbazole\/\">climbazole<\/a>.<\/li>\n<li>Ch\u1ea5t b\u1ea3o qu\u1ea3n trong m\u1ed9t s\u1ed1 m\u1ef9 ph\u1ea9m; s\u1eefa t\u1eafm kh\u1eed m\u00f9i.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>M\u1ef9 ph\u1ea9m t\u1ea1i Vi\u1ec7t Nam \u0111\u01b0\u1ee3c qu\u1ea3n l\u00fd theo Th\u00f4ng t\u01b0 06\/2011\/TT-BYT v\u00e0 Hi\u1ec7p \u0111\u1ecbnh h\u00f2a h\u1ee3p trong qu\u1ea3n l\u00fd m\u1ef9 ph\u1ea9m ASEAN. Danh m\u1ee5c ch\u1ea5t c\u1ea5m, ch\u1ea5t h\u1ea1n ch\u1ebf v\u00e0 ch\u1ea5t b\u1ea3o qu\u1ea3n c\u1ee7a ASEAN ph\u1ea7n l\u1edbn t\u01b0\u01a1ng \u0111\u1ed3ng v\u1edbi EU v\u00e0 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadt \u0111\u1ecbnh k\u1ef3. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu ph\u1ee5 l\u1ee5c ASEAN hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Piroctone olamine \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Piroctone_olamine\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Piroctone_olamine<\/a><\/li>\n<li>COSMILE Europe \u2013 Piroctone olamine \u2014 <a href=\"https:\/\/cosmileeurope.eu\/inci\/detail\/11818\/piroctone-olamine\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/cosmileeurope.eu\/inci\/detail\/11818\/piroctone-olamine\/<\/a><\/li>\n<li>SCCNFP \u2013 Opinion on piroctone olamine \u2014 <a href=\"https:\/\/ec.europa.eu\/health\/ph_risk\/committees\/sccp\/documents\/out162_en.pdf\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/ec.europa.eu\/health\/ph_risk\/committees\/sccp\/documents\/out162_en.pdf<\/a><\/li>\n<li>Wikidata \u2013 \u0111\u1ecbnh danh h\u00f3a h\u1ecdc (CAS, c\u00f4ng th\u1ee9c) \u2014 <a href=\"https:\/\/www.wikidata.org\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.wikidata.org\/<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Piroctone olamine: ho\u1ea1t ch\u1ea5t ch\u1ed1ng g\u00e0u \u2013 c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, gi\u1edbi h\u1ea1n Piroctone olamine l\u00e0 ho\u1ea1t ch\u1ea5t ch\u1ed1ng g\u00e0u v\u00e0 ch\u1ea5t b\u1ea3o qu\u1ea3n d\u00f9ng trong m\u1ef9 ph\u1ea9m ch\u0103m s\u00f3c t\u00f3c. \u0110\u00e2y l\u00e0 mu\u1ed1i ethanolamin (olamin) c\u1ee7a piroctone, m\u1ed9t d\u1eabn ch\u1ea5t hydroxypyridon. Ch\u1ea5t \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n t\u1ea1i \u0110\u1ee9c v\u00e0o th\u1eadp ni\u00ean 1970 v\u00e0 th\u01b0\u1eddng \u0111\u01b0\u1ee3c [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2947,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-885","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piroctone-olamine.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piroctone-olamine-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piroctone-olamine-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piroctone-olamine-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piroctone-olamine-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piroctone-olamine.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piroctone-olamine.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piroctone-olamine-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Piroctone olamine: ho\u1ea1t ch\u1ea5t ch\u1ed1ng g\u00e0u \u2013 c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, gi\u1edbi h\u1ea1n Piroctone olamine l\u00e0 ho\u1ea1t ch\u1ea5t ch\u1ed1ng g\u00e0u v\u00e0 ch\u1ea5t b\u1ea3o qu\u1ea3n d\u00f9ng trong m\u1ef9 ph\u1ea9m ch\u0103m s\u00f3c t\u00f3c. \u0110\u00e2y l\u00e0 mu\u1ed1i ethanolamin (olamin) c\u1ee7a piroctone, m\u1ed9t d\u1eabn ch\u1ea5t hydroxypyridon. Ch\u1ea5t \u0111\u01b0\u1ee3c ph\u00e1t tri\u1ec3n t\u1ea1i \u0110\u1ee9c v\u00e0o th\u1eadp ni\u00ean 1970 v\u00e0 th\u01b0\u1eddng \u0111\u01b0\u1ee3c&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/885","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=885"}],"version-history":[{"count":3,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/885\/revisions"}],"predecessor-version":[{"id":3702,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/885\/revisions\/3702"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2947"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=885"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=885"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=885"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}