{"id":880,"date":"2025-05-29T08:50:23","date_gmt":"2025-05-29T08:50:23","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-l-glutathione-reduced-shandong\/"},"modified":"2026-09-28T22:32:58","modified_gmt":"2026-09-28T15:32:58","slug":"nguyen-lieu-l-glutathione-reduced-shandong","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-l-glutathione-reduced-shandong\/","title":{"rendered":"Glutathione (L-glutathion d\u1ea1ng kh\u1eed): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t v\u00e0 s\u1ea3n xu\u1ea5t"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Glutathione (L-glutathion d\u1ea1ng kh\u1eed): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t v\u00e0 s\u1ea3n xu\u1ea5t<\/h1>\n<p><strong>Glutathione<\/strong> (GSH) l\u00e0 m\u1ed9t <strong>tripeptid<\/strong> g\u1ed3m ba acid amin: acid glutamic, cystein v\u00e0 glycin. Glutathion c\u00f3 m\u1eb7t \u1edf n\u1ed3ng \u0111\u1ed9 cao trong g\u1ea7n nh\u01b0 m\u1ecdi t\u1ebf b\u00e0o \u0111\u1ed9ng v\u1eadt, th\u1ef1c v\u1eadt v\u00e0 nhi\u1ec1u vi sinh v\u1eadt, \u0111\u00f3ng vai tr\u00f2 l\u00e0 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a n\u1ed9i b\u00e0o ch\u1ee7 y\u1ebfu v\u00e0 tham gia kh\u1eed \u0111\u1ed9c. &#8220;L-glutathione reduced&#8221; tr\u00ean nh\u00e3n nguy\u00ean li\u1ec7u ngh\u0129a l\u00e0 glutathion <strong>d\u1ea1ng kh\u1eed<\/strong>.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Glutathione, L-glutathion (d\u1ea1ng kh\u1eed, GSH), \u03b3-L-glutamyl-L-cysteinylglycin<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c, kh\u1ed1i l\u01b0\u1ee3ng mol<\/td>\n<td>C<sub>10<\/sub>H<sub>17<\/sub>N<sub>3<\/sub>O<sub>6<\/sub>S \u2013 307,33 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>70-18-8<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u1ea5u t\u1ea1o v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>\u0110i\u1ec3m \u0111\u1eb7c bi\u1ec7t: acid glutamic n\u1ed1i v\u1edbi cystein qua nh\u00f3m carboxyl \u1edf <strong>m\u1ea1ch b\u00ean (\u03b3)<\/strong>, kh\u00f4ng qua nh\u00f3m \u03b1 nh\u01b0 peptid th\u00f4ng th\u01b0\u1eddng. Li\u00ean k\u1ebft \u03b3 n\u00e0y gi\u00fap glutathion kh\u00f4ng b\u1ecb ph\u1ea7n l\u1edbn enzym peptidase ph\u00e2n c\u1eaft.<\/li>\n<li>Nh\u00f3m <strong>thiol (\u2013SH)<\/strong> c\u1ee7a cystein l\u00e0 trung t\u00e2m ho\u1ea1t t\u00ednh. Hai ph\u00e2n t\u1eed GSH b\u1ecb oxy h\u00f3a s\u1ebd n\u1ed1i v\u1edbi nhau b\u1eb1ng c\u1ea7u disulfid, t\u1ea1o <strong>glutathion d\u1ea1ng oxy h\u00f3a<\/strong> (GSSG). T\u1ef7 l\u1ec7 GSH\/GSSG ph\u1ea3n \u00e1nh tr\u1ea1ng th\u00e1i oxy h\u00f3a \u2013 kh\u1eed c\u1ee7a t\u1ebf b\u00e0o.<\/li>\n<li>B\u1ed9t k\u1ebft tinh m\u00e0u tr\u1eafng, tan t\u1ed1t trong n\u01b0\u1edbc, <strong>m\u00f9i l\u01b0u hu\u1ef3nh<\/strong> nh\u1eb9 \u0111\u1eb7c tr\u01b0ng.<\/li>\n<li>\u1ede d\u1ea1ng b\u1ed9t kh\u00f4, t\u01b0\u01a1ng \u0111\u1ed1i b\u1ec1n. <strong>Trong dung d\u1ecbch<\/strong>, GSH d\u1ec5 b\u1ecb oxy h\u00f3a th\u00e0nh GSSG, nh\u1ea5t l\u00e0 \u1edf pH trung t\u00ednh \u2013 ki\u1ec1m v\u00e0 khi c\u00f3 ion kim lo\u1ea1i. H\u00e0m l\u01b0\u1ee3ng GSSG l\u00e0 ch\u1ec9 ti\u00eau ch\u1ea5t l\u01b0\u1ee3ng quan tr\u1ecdng.<\/li>\n<\/ul>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>Glutathion th\u01b0\u01a1ng m\u1ea1i ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1eb1ng <strong>l\u00ean men n\u1ea5m men<\/strong> (<em>Saccharomyces cerevisiae<\/em>, <em>Candida utilis<\/em>) c\u00f3 h\u00e0m l\u01b0\u1ee3ng glutathion cao, sau \u0111\u00f3 chi\u1ebft t\u1eeb t\u1ebf b\u00e0o, tinh ch\u1ebf v\u00e0 k\u1ebft tinh. Ph\u01b0\u01a1ng ph\u00e1p enzym c\u0169ng \u0111\u01b0\u1ee3c d\u00f9ng.<\/p>\n<h2>Applications<\/h2>\n<ul>\n<li>Th\u1ef1c ph\u1ea9m b\u1ed5 sung (theo quy \u0111\u1ecbnh t\u1eebng n\u01b0\u1edbc); t\u1ea1i Nh\u1eadt B\u1ea3n glutathion n\u1ea5m men \u0111\u01b0\u1ee3c d\u00f9ng trong th\u1ef1c ph\u1ea9m.<\/li>\n<li>M\u1ef9 ph\u1ea9m: ch\u1ea5t ch\u1ed1ng oxy h\u00f3a, l\u00e0m s\u00e1ng da.<\/li>\n<li>D\u01b0\u1ee3c ph\u1ea9m; c\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n<h2>Ch\u1ea5t li\u00ean quan<\/h2>\n<ul>\n<li><a href=\"https:\/\/cpc1.vn\/en\/nguyen-lieu-s-acetyl-l-glutathione\/\">S-Acetyl-L-glutathione<\/a>; <a href=\"https:\/\/cpc1.vn\/en\/nguyen-lieu-l-cystine\/\">L-cystine<\/a>; N-acetylcystein.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Khi d\u00f9ng l\u00e0m th\u00e0nh ph\u1ea7n c\u1ee7a th\u1ef1c ph\u1ea9m ho\u1eb7c th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe, s\u1ea3n ph\u1ea9m tu\u00e2n theo Lu\u1eadt An to\u00e0n th\u1ef1c ph\u1ea9m, Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP v\u00e0 c\u00e1c v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n m\u1edbi nh\u1ea5t tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Glutathione \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Glutathione\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Glutathione<\/a><\/li>\n<li>Wikidata \u2013 glutathione (CAS 70-18-8) \u2014 <a href=\"https:\/\/www.wikidata.org\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.wikidata.org\/<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Glutathione (L-glutathion d\u1ea1ng kh\u1eed): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t v\u00e0 s\u1ea3n xu\u1ea5t Glutathione (GSH) l\u00e0 m\u1ed9t tripeptid g\u1ed3m ba acid amin: acid glutamic, cystein v\u00e0 glycin. Glutathion c\u00f3 m\u1eb7t \u1edf n\u1ed3ng \u0111\u1ed9 cao trong g\u1ea7n nh\u01b0 m\u1ecdi t\u1ebf b\u00e0o \u0111\u1ed9ng v\u1eadt, th\u1ef1c v\u1eadt v\u00e0 nhi\u1ec1u vi sinh v\u1eadt, \u0111\u00f3ng vai tr\u00f2 l\u00e0 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2916,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-880","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glutathione.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glutathione-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glutathione-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glutathione-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glutathione-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glutathione.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glutathione.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glutathione-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":1,"uagb_excerpt":"Glutathione (L-glutathion d\u1ea1ng kh\u1eed): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t v\u00e0 s\u1ea3n xu\u1ea5t Glutathione (GSH) l\u00e0 m\u1ed9t tripeptid g\u1ed3m ba acid amin: acid glutamic, cystein v\u00e0 glycin. Glutathion c\u00f3 m\u1eb7t \u1edf n\u1ed3ng \u0111\u1ed9 cao trong g\u1ea7n nh\u01b0 m\u1ecdi t\u1ebf b\u00e0o \u0111\u1ed9ng v\u1eadt, th\u1ef1c v\u1eadt v\u00e0 nhi\u1ec1u vi sinh v\u1eadt, \u0111\u00f3ng vai tr\u00f2 l\u00e0 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/880","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=880"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/880\/revisions"}],"predecessor-version":[{"id":3049,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/880\/revisions\/3049"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2916"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=880"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=880"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=880"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}