{"id":865,"date":"2025-05-29T08:42:29","date_gmt":"2025-05-29T08:42:29","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-chiet-xuat-xuyen-boi-mau-fritillaria-cirrhosa-extract\/"},"modified":"2026-09-30T15:25:05","modified_gmt":"2026-09-30T08:25:05","slug":"nguyen-lieu-chiet-xuat-xuyen-boi-mau-fritillaria-cirrhosa-extract","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-chiet-xuat-xuyen-boi-mau-fritillaria-cirrhosa-extract\/","title":{"rendered":"Chi\u1ebft xu\u1ea5t xuy\u00ean b\u1ed1i m\u1eabu (Fritillaria cirrhosa): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Chi\u1ebft xu\u1ea5t xuy\u00ean b\u1ed1i m\u1eabu (Fritillaria cirrhosa): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng<\/h1>\n<p><strong>Chi\u1ebft xu\u1ea5t xuy\u00ean b\u1ed1i m\u1eabu<\/strong> l\u00e0 cao chi\u1ebft t\u1eeb th\u00e2n h\u00e0nh c\u00e2y <em>Fritillaria cirrhosa<\/em>, v\u1ecb thu\u1ed1c \u0110\u00f4ng y qu\u00fd hi\u1ebfm m\u1ecdc \u1edf v\u00f9ng n\u00fai cao T\u1ee9 Xuy\u00ean, T\u00e2y T\u1ea1ng. Nh\u00f3m ho\u1ea1t ch\u1ea5t \u0111\u1eb7c tr\u01b0ng l\u00e0 <strong>alkaloid steroid<\/strong>.<\/p>\n<figure class=\"wp-block-image size-large cpc1-anh-cay\"><img decoding=\"async\" src=\"https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/fritillaria-cirrhosa-cay-nguyen-lieu.jpg\" alt=\"C\u00e2y xuy\u00ean b\u1ed1i m\u1eabu \u2013 Fritillaria cirrhosa, ngu\u1ed3n nguy\u00ean li\u1ec7u chi\u1ebft xu\u1ea5t\"\/><figcaption>Xuy\u00ean b\u1ed1i m\u1eabu (<em>Fritillaria cirrhosa<\/em>). \u1ea2nh: Fumikas Sagisavas, <a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Fritillaria_cirrhosa_granules.jpg\" rel=\"nofollow noopener\" target=\"_blank\">Wikimedia Commons<\/a>, gi\u1ea5y ph\u00e9p <a href=\"https:\/\/creativecommons.org\/publicdomain\/zero\/1.0\/\" rel=\"nofollow noopener\" target=\"_blank\">CC0<\/a>.<\/figcaption><\/figure>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Xuy\u00ean b\u1ed1i m\u1eabu, b\u1ed1i m\u1eabu; Fritillariae cirrhosae bulbus<\/td>\n<\/tr>\n<tr>\n<td>Lo\u00e0i<\/td>\n<td><em>Fritillaria cirrhosa D.Don<\/em>, h\u1ecd Loa k\u00e8n (Liliaceae)<\/td>\n<\/tr>\n<tr>\n<td>B\u1ed9 ph\u1eadn d\u00f9ng<\/td>\n<td>Th\u00e2n h\u00e0nh (gi\u00f2)<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ho\u1ea1t ch\u1ea5t ch\u00ednh<\/td>\n<td>Alkaloid steroid isosteroidal (imperialin, peimin, peiminin, verticinon)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u00e2y v\u00e0 d\u01b0\u1ee3c li\u1ec7u<\/h2>\n<p>Xuy\u00ean b\u1ed1i m\u1eabu l\u00e0 c\u00e2y th\u1ea3o nh\u1ecf c\u00f3 th\u00e2n h\u00e0nh, hoa h\u00ecnh chu\u00f4ng r\u1ee7 xu\u1ed1ng c\u00f3 v\u00e2n \u00f4 vu\u00f4ng nh\u01b0 b\u00e0n c\u1edd, m\u1ecdc \u1edf \u0111\u1ed3ng c\u1ecf n\u00fai cao 3.000\u20134.500 m. Ngu\u1ed3n t\u1ef1 nhi\u00ean ng\u00e0y c\u00e0ng khan hi\u1ebfm n\u00ean gi\u00e1 r\u1ea5t cao; c\u00f3 nhi\u1ec1u lo\u00e0i <em>Fritillaria<\/em> kh\u00e1c (chi\u1ebft b\u1ed1i m\u1eabu, b\u00ecnh b\u1ed1i m\u1eabu, y b\u1ed1i m\u1eabu) r\u1ebb h\u01a1n, d\u1ec5 b\u1ecb d\u00f9ng thay.<\/p>\n<h2>Th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc<\/h2>\n<ul>\n<li><strong>Alkaloid isosteroidal<\/strong>: imperialin, peimin (verticin), peiminin, verticinon, chuanbeinon.<\/li>\n<li>Nucleosid, saponin steroid.<\/li>\n<\/ul>\n<h2>Chi\u1ebft xu\u1ea5t v\u00e0 ti\u00eau chu\u1ea9n h\u00f3a<\/h2>\n<p>Th\u00e2n h\u00e0nh kh\u00f4 \u0111\u01b0\u1ee3c chi\u1ebft b\u1eb1ng ethanol \u2013 n\u01b0\u1edbc c\u00f3 acid (\u0111\u1ec3 h\u00f2a tan alkaloid), c\u00f4 \u0111\u1eb7c v\u00e0 s\u1ea5y; nguy\u00ean li\u1ec7u th\u01b0\u1eddng ghi t\u1ef7 l\u1ec7 chi\u1ebft ho\u1eb7c h\u00e0m l\u01b0\u1ee3ng alkaloid to\u00e0n ph\u1ea7n, imperialin.<\/p>\n<h2>Ch\u1ec9 ti\u00eau ch\u1ea5t l\u01b0\u1ee3ng n\u00ean xem<\/h2>\n<ul>\n<li>Alkaloid to\u00e0n ph\u1ea7n, imperialin, peimin (HPLC-ELSD\/MS); <strong>x\u00e1c \u0111\u1ecbnh lo\u00e0i<\/strong> \u2013 nguy c\u01a1 thay th\u1ebf b\u1eb1ng lo\u00e0i <em>Fritillaria<\/em> r\u1ebb h\u01a1n r\u1ea5t cao.<\/li>\n<li>Kim lo\u1ea1i n\u1eb7ng, vi sinh v\u1eadt, d\u01b0 l\u01b0\u1ee3ng thu\u1ed1c b\u1ea3o v\u1ec7 th\u1ef1c v\u1eadt; \u0111\u1ed9c t\u1ed1 vi n\u1ea5m v\u1edbi d\u01b0\u1ee3c li\u1ec7u d\u1ec5 m\u1ed1c.<\/li>\n<\/ul>\n<h2>Applications<\/h2>\n<ul>\n<li>Thu\u1ed1c d\u01b0\u1ee3c li\u1ec7u (siro, vi\u00ean ph\u1ed1i h\u1ee3p), th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe.<\/li>\n<li>C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n<h2>An to\u00e0n v\u00e0 l\u01b0u \u00fd<\/h2>\n<ul>\n<li>Alkaloid <em>Fritillaria<\/em> c\u00f3 \u0111\u1ed9c t\u00ednh \u1edf li\u1ec1u cao; kh\u00f4ng t\u1ef1 \u00fd d\u00f9ng l\u01b0\u1ee3ng l\u1edbn.<\/li>\n<li>Ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u an to\u00e0n cho ph\u1ee5 n\u1eef mang thai, cho con b\u00fa v\u00e0 tr\u1ebb em; ng\u01b0\u1eddi \u0111ang d\u00f9ng thu\u1ed1c n\u00ean h\u1ecfi \u00fd ki\u1ebfn chuy\u00ean gia y t\u1ebf.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Khi d\u00f9ng l\u00e0m th\u00e0nh ph\u1ea7n c\u1ee7a th\u1ef1c ph\u1ea9m ho\u1eb7c th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe, s\u1ea3n ph\u1ea9m tu\u00e2n theo Lu\u1eadt An to\u00e0n th\u1ef1c ph\u1ea9m, Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP v\u00e0 c\u00e1c v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n m\u1edbi nh\u1ea5t tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Fritillaria cirrhosa \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Fritillaria_cirrhosa\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Fritillaria_cirrhosa<\/a><\/li>\n<li>Wikipedia \u2013 Imperialine \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Imperialine\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Imperialine<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Chi\u1ebft xu\u1ea5t xuy\u00ean b\u1ed1i m\u1eabu (Fritillaria cirrhosa): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t xuy\u00ean b\u1ed1i m\u1eabu l\u00e0 cao chi\u1ebft t\u1eeb th\u00e2n h\u00e0nh c\u00e2y Fritillaria cirrhosa, v\u1ecb thu\u1ed1c \u0110\u00f4ng y qu\u00fd hi\u1ebfm m\u1ecdc \u1edf v\u00f9ng n\u00fai cao T\u1ee9 Xuy\u00ean, T\u00e2y T\u1ea1ng. Nh\u00f3m ho\u1ea1t ch\u1ea5t \u0111\u1eb7c tr\u01b0ng l\u00e0 alkaloid steroid. Xuy\u00ean b\u1ed1i m\u1eabu (Fritillaria [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2015,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-865","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/fritillaria-cirrhosa-cay-nguyen-lieu.jpg",1200,900,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/fritillaria-cirrhosa-cay-nguyen-lieu-150x150.jpg",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/fritillaria-cirrhosa-cay-nguyen-lieu-300x225.jpg",300,225,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/fritillaria-cirrhosa-cay-nguyen-lieu-768x576.jpg",768,576,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/fritillaria-cirrhosa-cay-nguyen-lieu-1024x768.jpg",1024,768,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/fritillaria-cirrhosa-cay-nguyen-lieu.jpg",1200,900,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/fritillaria-cirrhosa-cay-nguyen-lieu.jpg",1200,900,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/fritillaria-cirrhosa-cay-nguyen-lieu-16x12.jpg",16,12,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Chi\u1ebft xu\u1ea5t xuy\u00ean b\u1ed1i m\u1eabu (Fritillaria cirrhosa): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t xuy\u00ean b\u1ed1i m\u1eabu l\u00e0 cao chi\u1ebft t\u1eeb th\u00e2n h\u00e0nh c\u00e2y Fritillaria cirrhosa, v\u1ecb thu\u1ed1c \u0110\u00f4ng y qu\u00fd hi\u1ebfm m\u1ecdc \u1edf v\u00f9ng n\u00fai cao T\u1ee9 Xuy\u00ean, T\u00e2y T\u1ea1ng. Nh\u00f3m ho\u1ea1t ch\u1ea5t \u0111\u1eb7c tr\u01b0ng l\u00e0 alkaloid steroid. Xuy\u00ean b\u1ed1i m\u1eabu (Fritillaria&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/865","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=865"}],"version-history":[{"count":3,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/865\/revisions"}],"predecessor-version":[{"id":5071,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/865\/revisions\/5071"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2015"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=865"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=865"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=865"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}