{"id":860,"date":"2025-05-29T08:39:58","date_gmt":"2025-05-29T08:39:58","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-chiet-xuat-tu-la-trau-khong-piper-betle-extract\/"},"modified":"2026-09-30T15:24:50","modified_gmt":"2026-09-30T08:24:50","slug":"nguyen-lieu-chiet-xuat-tu-la-trau-khong-piper-betle-extract","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-chiet-xuat-tu-la-trau-khong-piper-betle-extract\/","title":{"rendered":"Chi\u1ebft xu\u1ea5t l\u00e1 tr\u1ea7u kh\u00f4ng (Piper betle): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Chi\u1ebft xu\u1ea5t l\u00e1 tr\u1ea7u kh\u00f4ng (Piper betle): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng<\/h1>\n<p><strong>Chi\u1ebft xu\u1ea5t l\u00e1 tr\u1ea7u kh\u00f4ng<\/strong> l\u00e0 cao chi\u1ebft ho\u1eb7c tinh d\u1ea7u t\u1eeb l\u00e1 c\u00e2y tr\u1ea7u kh\u00f4ng (<em>Piper betle<\/em>), lo\u1ea1i l\u00e1 quen thu\u1ed9c trong t\u1ee5c \u0103n tr\u1ea7u c\u1ee7a ng\u01b0\u1eddi Vi\u1ec7t. M\u00f9i th\u01a1m cay n\u1ed3ng c\u1ee7a l\u00e1 \u0111\u1ebfn t\u1eeb nh\u00f3m <strong>phenol<\/strong> trong tinh d\u1ea7u, \u0111\u1eb7c bi\u1ec7t l\u00e0 <strong>hydroxychavicol<\/strong> v\u00e0 <strong>eugenol<\/strong>.<\/p>\n<figure class=\"wp-block-image size-large cpc1-anh-cay\"><img decoding=\"async\" src=\"https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piper-betle-cay-nguyen-lieu.jpg\" alt=\"C\u00e2y tr\u1ea7u kh\u00f4ng \u2013 Piper betle, ngu\u1ed3n nguy\u00ean li\u1ec7u chi\u1ebft xu\u1ea5t\"\/><figcaption>Tr\u1ea7u kh\u00f4ng (<em>Piper betle<\/em>). \u1ea2nh: <a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Piper_betle_plant.jpg\" rel=\"nofollow noopener\" target=\"_blank\">Wikimedia Commons<\/a>, gi\u1ea5y ph\u00e9p <a href=\"https:\/\/creativecommons.org\/publicdomain\/mark\/1.0\/\" rel=\"nofollow noopener\" target=\"_blank\">Public domain<\/a>.<\/figcaption><\/figure>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Tr\u1ea7u kh\u00f4ng, tr\u1ea7u, betel leaf<\/td>\n<\/tr>\n<tr>\n<td>Lo\u00e0i<\/td>\n<td><em>Piper betle L.<\/em>, h\u1ecd H\u1ed3 ti\u00eau (Piperaceae)<\/td>\n<\/tr>\n<tr>\n<td>B\u1ed9 ph\u1eadn d\u00f9ng<\/td>\n<td>L\u00e1<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ho\u1ea1t ch\u1ea5t ch\u00ednh<\/td>\n<td>Phenol trong tinh d\u1ea7u (hydroxychavicol, eugenol, chavibetol, chavicol), acid phenolic<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u00e2y v\u00e0 d\u01b0\u1ee3c li\u1ec7u<\/h2>\n<p>Tr\u1ea7u kh\u00f4ng l\u00e0 d\u00e2y leo c\u00f9ng chi v\u1edbi h\u1ed3 ti\u00eau, l\u00e1 h\u00ecnh tim d\u00e0y, b\u00f3ng, m\u00f9i th\u01a1m h\u1eafc. C\u00e2y \u0111\u01b0\u1ee3c tr\u1ed3ng kh\u1eafp Nam \u00c1 v\u00e0 \u0110\u00f4ng Nam \u00c1.<\/p>\n<h2>Th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc<\/h2>\n<ul>\n<li><strong>Tinh d\u1ea7u<\/strong> (kho\u1ea3ng 1\u20132% l\u00e1 t\u01b0\u01a1i t\u00f9y gi\u1ed1ng): hydroxychavicol, eugenol, chavibetol, chavicol, allylpyrocatechol.<\/li>\n<li>Acid phenolic, flavonoid, tanin.<\/li>\n<\/ul>\n<h2>Chi\u1ebft xu\u1ea5t v\u00e0 ti\u00eau chu\u1ea9n h\u00f3a<\/h2>\n<p>L\u00e1 t\u01b0\u01a1i ho\u1eb7c kh\u00f4 \u0111\u01b0\u1ee3c ch\u01b0ng c\u1ea5t l\u1ea5y tinh d\u1ea7u, ho\u1eb7c chi\u1ebft b\u1eb1ng n\u01b0\u1edbc, ethanol \u2013 n\u01b0\u1edbc, glycol; nguy\u00ean li\u1ec7u th\u01b0\u1eddng ghi t\u1ef7 l\u1ec7 chi\u1ebft ho\u1eb7c h\u00e0m l\u01b0\u1ee3ng hydroxychavicol, phenol to\u00e0n ph\u1ea7n. D\u1ea1ng l\u1ecfng d\u00f9ng cho s\u1ea3n ph\u1ea9m v\u1ec7 sinh.<\/p>\n<h2>Ch\u1ec9 ti\u00eau ch\u1ea5t l\u01b0\u1ee3ng n\u00ean xem<\/h2>\n<ul>\n<li>Hydroxychavicol, eugenol (HPLC\/GC).<\/li>\n<li>Kim lo\u1ea1i n\u1eb7ng, vi sinh v\u1eadt, d\u01b0 l\u01b0\u1ee3ng thu\u1ed1c b\u1ea3o v\u1ec7 th\u1ef1c v\u1eadt; \u0111\u1ed9c t\u1ed1 vi n\u1ea5m v\u1edbi d\u01b0\u1ee3c li\u1ec7u d\u1ec5 m\u1ed1c.<\/li>\n<\/ul>\n<h2>Applications<\/h2>\n<ul>\n<li>S\u1ea3n ph\u1ea9m v\u1ec7 sinh c\u00e1 nh\u00e2n, dung d\u1ecbch v\u1ec7 sinh, n\u01b0\u1edbc s\u00fac mi\u1ec7ng, x\u00e0 ph\u00f2ng.<\/li>\n<li>M\u1ef9 ph\u1ea9m; th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe (theo quy \u0111\u1ecbnh).<\/li>\n<li>C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n<h2>An to\u00e0n v\u00e0 l\u01b0u \u00fd<\/h2>\n<ul>\n<li>IARC x\u1ebfp <strong>mi\u1ebfng tr\u1ea7u<\/strong> (tr\u1ea7u cau, c\u00f3 ho\u1eb7c kh\u00f4ng c\u00f3 thu\u1ed1c l\u00e1) v\u00e0o nh\u00f3m 1 \u2013 g\u00e2y ung th\u01b0 cho ng\u01b0\u1eddi; nguy c\u01a1 ch\u1ee7 y\u1ebfu li\u00ean quan \u0111\u1ebfn <strong>h\u1ea1t cau<\/strong> (areca) ch\u1ee9 kh\u00f4ng ph\u1ea3i ri\u00eang l\u00e1 tr\u1ea7u, nh\u01b0ng ng\u01b0\u1eddi ti\u00eau d\u00f9ng c\u1ea7n \u0111\u01b0\u1ee3c th\u00f4ng tin \u0111\u00fang.<\/li>\n<li>Tinh d\u1ea7u \u0111\u1eadm \u0111\u1eb7c c\u00f3 th\u1ec3 g\u00e2y k\u00edch \u1ee9ng da, ni\u00eam m\u1ea1c.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Khi d\u00f9ng trong m\u1ef9 ph\u1ea9m, s\u1ea3n ph\u1ea9m \u0111\u01b0\u1ee3c qu\u1ea3n l\u00fd theo Th\u00f4ng t\u01b0 06\/2011\/TT-BYT v\u00e0 Hi\u1ec7p \u0111\u1ecbnh h\u00f2a h\u1ee3p trong qu\u1ea3n l\u00fd m\u1ef9 ph\u1ea9m ASEAN; khi d\u00f9ng trong th\u1ef1c ph\u1ea9m, theo Lu\u1eadt An to\u00e0n th\u1ef1c ph\u1ea9m v\u00e0 Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Betel \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Betel\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Betel<\/a><\/li>\n<li>Wikipedia \u2013 Betel nut chewing \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Betel_nut_chewing\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Betel_nut_chewing<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Chi\u1ebft xu\u1ea5t l\u00e1 tr\u1ea7u kh\u00f4ng (Piper betle): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t l\u00e1 tr\u1ea7u kh\u00f4ng l\u00e0 cao chi\u1ebft ho\u1eb7c tinh d\u1ea7u t\u1eeb l\u00e1 c\u00e2y tr\u1ea7u kh\u00f4ng (Piper betle), lo\u1ea1i l\u00e1 quen thu\u1ed9c trong t\u1ee5c \u0103n tr\u1ea7u c\u1ee7a ng\u01b0\u1eddi Vi\u1ec7t. M\u00f9i th\u01a1m cay n\u1ed3ng c\u1ee7a l\u00e1 \u0111\u1ebfn t\u1eeb nh\u00f3m phenol trong tinh [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1985,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-860","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piper-betle-cay-nguyen-lieu.jpg",1200,900,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piper-betle-cay-nguyen-lieu-150x150.jpg",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piper-betle-cay-nguyen-lieu-300x225.jpg",300,225,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piper-betle-cay-nguyen-lieu-768x576.jpg",768,576,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piper-betle-cay-nguyen-lieu-1024x768.jpg",1024,768,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piper-betle-cay-nguyen-lieu.jpg",1200,900,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piper-betle-cay-nguyen-lieu.jpg",1200,900,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/piper-betle-cay-nguyen-lieu-16x12.jpg",16,12,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Chi\u1ebft xu\u1ea5t l\u00e1 tr\u1ea7u kh\u00f4ng (Piper betle): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t l\u00e1 tr\u1ea7u kh\u00f4ng l\u00e0 cao chi\u1ebft ho\u1eb7c tinh d\u1ea7u t\u1eeb l\u00e1 c\u00e2y tr\u1ea7u kh\u00f4ng (Piper betle), lo\u1ea1i l\u00e1 quen thu\u1ed9c trong t\u1ee5c \u0103n tr\u1ea7u c\u1ee7a ng\u01b0\u1eddi Vi\u1ec7t. M\u00f9i th\u01a1m cay n\u1ed3ng c\u1ee7a l\u00e1 \u0111\u1ebfn t\u1eeb nh\u00f3m phenol trong tinh&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/860","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=860"}],"version-history":[{"count":3,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/860\/revisions"}],"predecessor-version":[{"id":5068,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/860\/revisions\/5068"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/1985"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=860"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=860"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=860"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}