{"id":825,"date":"2025-05-29T08:22:59","date_gmt":"2025-05-29T08:22:59","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-chiet-xuat-hoa-cuc-van-tho-marigold-extract-10-lutein\/"},"modified":"2026-09-29T18:57:21","modified_gmt":"2026-09-29T11:57:21","slug":"nguyen-lieu-chiet-xuat-hoa-cuc-van-tho-marigold-extract-10-lutein","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-chiet-xuat-hoa-cuc-van-tho-marigold-extract-10-lutein\/","title":{"rendered":"Lutein v\u00e0 zeaxanthin (chi\u1ebft xu\u1ea5t hoa c\u00fac v\u1ea1n th\u1ecd): c\u1ea5u t\u1ea1o, s\u1ea3n xu\u1ea5t, quy \u0111\u1ecbnh"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Lutein v\u00e0 zeaxanthin (chi\u1ebft xu\u1ea5t hoa c\u00fac v\u1ea1n th\u1ecd): c\u1ea5u t\u1ea1o, s\u1ea3n xu\u1ea5t, quy \u0111\u1ecbnh<\/h1>\n<p><strong>Lutein<\/strong> v\u00e0 <strong>zeaxanthin<\/strong> l\u00e0 hai <strong>carotenoid<\/strong> nh\u00f3m xanthophyll m\u00e0u v\u00e0ng cam. Ch\u00fang l\u00e0 \u0111\u1ed3ng ph\u00e2n c\u1ee7a nhau (c\u00f9ng c\u00f4ng th\u1ee9c C<sub>40<\/sub>H<sub>56<\/sub>O<sub>2<\/sub>), ch\u1ec9 kh\u00e1c v\u1ecb tr\u00ed m\u1ed9t li\u00ean k\u1ebft \u0111\u00f4i trong v\u00f2ng cu\u1ed1i. Hai ch\u1ea5t c\u00f3 trong rau l\u00e1 xanh \u0111\u1eadm, l\u00f2ng \u0111\u1ecf tr\u1ee9ng, ng\u00f4, v\u00e0 t\u1eadp trung \u1edf \u0111i\u1ec3m v\u00e0ng c\u1ee7a v\u00f5ng m\u1ea1c m\u1eaft ng\u01b0\u1eddi. Ngu\u1ed3n c\u00f4ng nghi\u1ec7p ch\u00ednh l\u00e0 <strong>hoa c\u00fac v\u1ea1n th\u1ecd<\/strong> (<em>Tagetes erecta<\/em>).<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Lutein (E161b); zeaxanthin (E161h)<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c, kh\u1ed1i l\u01b0\u1ee3ng mol<\/td>\n<td>C<sub>40<\/sub>H<sub>56<\/sub>O<sub>2<\/sub> \u2013 568,89 g\/mol (c\u1ea3 hai)<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>127-40-2 (lutein); 144-68-3 (zeaxanthin)<\/td>\n<\/tr>\n<tr>\n<td>Ngu\u1ed3n<\/td>\n<td>C\u00e1nh hoa c\u00fac v\u1ea1n th\u1ecd, <em>Tagetes erecta<\/em> L., h\u1ecd C\u00fac (Asteraceae)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>T\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>Chu\u1ed7i polyen li\u00ean h\u1ee3p d\u00e0i t\u1ea1o m\u00e0u v\u00e0ng cam v\u00e0 kh\u1ea3 n\u0103ng h\u1ea5p th\u1ee5 \u00e1nh s\u00e1ng xanh.<\/li>\n<li>Kh\u00f4ng tan trong n\u01b0\u1edbc, tan trong d\u1ea7u (\u00edt). R\u1ea5t nh\u1ea1y v\u1edbi \u00e1nh s\u00e1ng, oxy, nhi\u1ec7t v\u00e0 acid.<\/li>\n<li>Trong hoa c\u00fac v\u1ea1n th\u1ecd, lutein t\u1ed3n t\u1ea1i ch\u1ee7 y\u1ebfu \u1edf d\u1ea1ng <strong>ester<\/strong> v\u1edbi acid b\u00e9o (lutein ester). Hoa ch\u1ee9a nhi\u1ec1u lutein h\u01a1n h\u1eb3n zeaxanthin.<\/li>\n<\/ul>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>C\u00e1nh hoa c\u00fac v\u1ea1n th\u1ecd \u0111\u01b0\u1ee3c \u1ee7, s\u1ea5y, chi\u1ebft b\u1eb1ng dung m\u00f4i th\u00e0nh <strong>oleoresin<\/strong> ch\u1ee9a lutein ester. Oleoresin \u0111\u01b0\u1ee3c <strong>x\u00e0 ph\u00f2ng h\u00f3a<\/strong> \u0111\u1ec3 gi\u1ea3i ph\u00f3ng lutein t\u1ef1 do, sau \u0111\u00f3 k\u1ebft tinh. M\u1ed9t ph\u1ea7n lutein c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c \u0111\u1ed3ng ph\u00e2n h\u00f3a th\u00e0nh zeaxanthin (meso-zeaxanthin) \u0111\u1ec3 t\u0103ng t\u1ef7 l\u1ec7 zeaxanthin. S\u1ea3n ph\u1ea9m cu\u1ed1i l\u00e0 tinh th\u1ec3 ho\u1eb7c \u0111\u01b0\u1ee3c pha th\u00e0nh d\u1ea1ng d\u1ea7u, d\u1ea1ng b\u1ed9t vi nang ti\u00eau chu\u1ea9n h\u00f3a, v\u00ed d\u1ee5 5%, 10%, 20% lutein ho\u1eb7c zeaxanthin.<\/p>\n<h2>Applications<\/h2>\n<ul>\n<li>Th\u1ef1c ph\u1ea9m b\u1ed5 sung (d\u1ea1ng vi\u00ean nang m\u1ec1m, b\u1ed9t); s\u1eefa c\u00f4ng th\u1ee9c.<\/li>\n<li>Ph\u1ea9m m\u00e0u v\u00e0ng cho th\u1ef1c ph\u1ea9m, \u0111\u1ed3 u\u1ed1ng.<\/li>\n<li>Th\u1ee9c \u0103n gia c\u1ea7m: t\u1ea1o m\u00e0u l\u00f2ng \u0111\u1ecf tr\u1ee9ng, da g\u00e0.<\/li>\n<\/ul>\n<h2>An to\u00e0n v\u00e0 ph\u00e1p l\u00fd<\/h2>\n<ul>\n<li><strong>JECFA<\/strong> \u0111\u1eb7t ADI nh\u00f3m cho lutein v\u00e0 zeaxanthin l\u00e0 0\u20132 mg\/kg th\u1ec3 tr\u1ecdng.<\/li>\n<li><strong>Vi\u1ec7t Nam<\/strong>: lutein t\u1eeb <em>Tagetes erecta<\/em> (INS 161b(i)), lutein ester t\u1eeb <em>Tagetes erecta<\/em> (161b(iii)) v\u00e0 zeaxanthin t\u1ed5ng h\u1ee3p (161h(i)) c\u00f3 trong danh m\u1ee5c ph\u1ee5 gia ph\u1ea9m m\u00e0u \u0111\u01b0\u1ee3c ph\u00e9p theo Th\u00f4ng t\u01b0 24\/2019\/TT-BYT.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Khi d\u00f9ng l\u00e0m th\u00e0nh ph\u1ea7n c\u1ee7a th\u1ef1c ph\u1ea9m ho\u1eb7c th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe, s\u1ea3n ph\u1ea9m tu\u00e2n theo Lu\u1eadt An to\u00e0n th\u1ef1c ph\u1ea9m, Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP v\u00e0 c\u00e1c v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n m\u1edbi nh\u1ea5t tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Lutein \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Lutein\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Lutein<\/a><\/li>\n<li>Wikipedia \u2013 Zeaxanthin \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Zeaxanthin\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Zeaxanthin<\/a><\/li>\n<li>Wikidata \u2013 \u0111\u1ecbnh danh h\u00f3a h\u1ecdc (CAS, c\u00f4ng th\u1ee9c, m\u00e3 E) \u2014 <a href=\"https:\/\/www.wikidata.org\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.wikidata.org\/<\/a><\/li>\n<li>JECFA (FAO\/WHO) \u2013 c\u01a1 s\u1edf d\u1eef li\u1ec7u \u0111\u00e1nh gi\u00e1 ph\u1ee5 gia th\u1ef1c ph\u1ea9m \u2014 <a href=\"https:\/\/apps.who.int\/food-additives-contaminants-jecfa-database\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/apps.who.int\/food-additives-contaminants-jecfa-database\/<\/a><\/li>\n<li>B\u1ed9 Y t\u1ebf \u2013 Th\u00f4ng t\u01b0 24\/2019\/TT-BYT v\u1ec1 qu\u1ea3n l\u00fd v\u00e0 s\u1eed d\u1ee5ng ph\u1ee5 gia th\u1ef1c ph\u1ea9m, Ph\u1ee5 l\u1ee5c 1 \u2014 <a href=\"https:\/\/vfa.gov.vn\/van-ban\/thong-tu-so-242019tt-byt-quy-dinh-ve-quan-ly-va-su-dung-phu-gia-thuc-pham.html\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/vfa.gov.vn\/van-ban\/thong-tu-so-242019tt-byt-quy-dinh-ve-quan-ly-va-su-dung-phu-gia-thuc-pham.html<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Lutein v\u00e0 zeaxanthin (chi\u1ebft xu\u1ea5t hoa c\u00fac v\u1ea1n th\u1ecd): c\u1ea5u t\u1ea1o, s\u1ea3n xu\u1ea5t, quy \u0111\u1ecbnh Lutein v\u00e0 zeaxanthin l\u00e0 hai carotenoid nh\u00f3m xanthophyll m\u00e0u v\u00e0ng cam. Ch\u00fang l\u00e0 \u0111\u1ed3ng ph\u00e2n c\u1ee7a nhau (c\u00f9ng c\u00f4ng th\u1ee9c C40H56O2), ch\u1ec9 kh\u00e1c v\u1ecb tr\u00ed m\u1ed9t li\u00ean k\u1ebft \u0111\u00f4i trong v\u00f2ng cu\u1ed1i. Hai ch\u1ea5t c\u00f3 trong rau l\u00e1 xanh \u0111\u1eadm, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2010,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-825","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tagetes-erecta-cay-nguyen-lieu.jpg",1200,900,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tagetes-erecta-cay-nguyen-lieu-150x150.jpg",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tagetes-erecta-cay-nguyen-lieu-300x225.jpg",300,225,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tagetes-erecta-cay-nguyen-lieu-768x576.jpg",768,576,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tagetes-erecta-cay-nguyen-lieu-1024x768.jpg",1024,768,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tagetes-erecta-cay-nguyen-lieu.jpg",1200,900,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tagetes-erecta-cay-nguyen-lieu.jpg",1200,900,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tagetes-erecta-cay-nguyen-lieu-16x12.jpg",16,12,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Lutein v\u00e0 zeaxanthin (chi\u1ebft xu\u1ea5t hoa c\u00fac v\u1ea1n th\u1ecd): c\u1ea5u t\u1ea1o, s\u1ea3n xu\u1ea5t, quy \u0111\u1ecbnh Lutein v\u00e0 zeaxanthin l\u00e0 hai carotenoid nh\u00f3m xanthophyll m\u00e0u v\u00e0ng cam. Ch\u00fang l\u00e0 \u0111\u1ed3ng ph\u00e2n c\u1ee7a nhau (c\u00f9ng c\u00f4ng th\u1ee9c C40H56O2), ch\u1ec9 kh\u00e1c v\u1ecb tr\u00ed m\u1ed9t li\u00ean k\u1ebft \u0111\u00f4i trong v\u00f2ng cu\u1ed1i. Hai ch\u1ea5t c\u00f3 trong rau l\u00e1 xanh \u0111\u1eadm,&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/825","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=825"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/825\/revisions"}],"predecessor-version":[{"id":3069,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/825\/revisions\/3069"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2010"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=825"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=825"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=825"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}