{"id":794,"date":"2025-05-29T08:07:24","date_gmt":"2025-05-29T08:07:24","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-chiet-xuat-doc-hoat-angelica-pubescens-extract\/"},"modified":"2026-09-28T22:28:11","modified_gmt":"2026-09-28T15:28:11","slug":"nguyen-lieu-chiet-xuat-doc-hoat-angelica-pubescens-extract","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-chiet-xuat-doc-hoat-angelica-pubescens-extract\/","title":{"rendered":"Chi\u1ebft xu\u1ea5t \u0111\u1ed9c ho\u1ea1t (Angelica pubescens): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Chi\u1ebft xu\u1ea5t \u0111\u1ed9c ho\u1ea1t (Angelica pubescens): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng<\/h1>\n<p><strong>Chi\u1ebft xu\u1ea5t \u0111\u1ed9c ho\u1ea1t<\/strong> l\u00e0 cao chi\u1ebft t\u1eeb r\u1ec5 c\u00e2y \u0111\u1ed9c ho\u1ea1t (<em>Angelica pubescens<\/em>), v\u1ecb thu\u1ed1c \u0110\u00f4ng y th\u01b0\u1eddng c\u00f3 trong c\u00e1c b\u00e0i ph\u1ed1i h\u1ee3p (v\u00ed d\u1ee5 b\u00e0i &#8220;\u0111\u1ed9c ho\u1ea1t tang k\u00fd sinh&#8221;). Nh\u00f3m ho\u1ea1t ch\u1ea5t \u0111\u1eb7c tr\u01b0ng l\u00e0 <strong>coumarin<\/strong>.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>\u0110\u1ed9c ho\u1ea1t, h\u01b0\u01a1ng \u0111\u1ed9c ho\u1ea1t; Angelicae pubescentis radix<\/td>\n<\/tr>\n<tr>\n<td>Lo\u00e0i<\/td>\n<td><em>Angelica pubescens Maxim. f. biserrata R.H.Shan &#038; C.Q.Yuan<\/em>, h\u1ecd Hoa t\u00e1n (Apiaceae)<\/td>\n<\/tr>\n<tr>\n<td>B\u1ed9 ph\u1eadn d\u00f9ng<\/td>\n<td>R\u1ec5<\/td>\n<\/tr>\n<tr>\n<td>Chuy\u00ean lu\u1eadn<\/td>\n<td>D\u01b0\u1ee3c \u0111i\u1ec3n Vi\u1ec7t Nam V: \u0110\u1ed9c ho\u1ea1t (r\u1ec5)<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ho\u1ea1t ch\u1ea5t ch\u00ednh<\/td>\n<td>Coumarin: osthol, columbianadin, columbianetin acetat<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u00e2y v\u00e0 d\u01b0\u1ee3c li\u1ec7u<\/h2>\n<p>\u0110\u1ed9c ho\u1ea1t l\u00e0 c\u00e2y th\u1ea3o s\u1ed1ng l\u00e2u n\u0103m h\u1ecd Hoa t\u00e1n, c\u00f9ng chi v\u1edbi <a href=\"https:\/\/cpc1.vn\/en\/nguyen-lieu-chiet-xuat-duong-quy-angelica-sinensis-extract\/\">\u0111\u01b0\u01a1ng quy<\/a>, r\u1ec5 m\u00e0u n\u00e2u x\u00e1m, m\u00f9i th\u01a1m \u0111\u1eb7c bi\u1ec7t. D\u01b0\u1ee3c li\u1ec7u ch\u1ee7 y\u1ebfu nh\u1eadp t\u1eeb Trung Qu\u1ed1c.<\/p>\n<h2>Th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc<\/h2>\n<ul>\n<li><strong>Coumarin<\/strong>: osthol v\u00e0 columbianadin (ch\u1ea5t \u0111\u00e1nh d\u1ea5u theo D\u01b0\u1ee3c \u0111i\u1ec3n Trung Qu\u1ed1c), columbianetin acetat, bergapten.<\/li>\n<li>Tinh d\u1ea7u, phytosterol.<\/li>\n<\/ul>\n<h2>Chi\u1ebft xu\u1ea5t v\u00e0 ti\u00eau chu\u1ea9n h\u00f3a<\/h2>\n<p>R\u1ec5 kh\u00f4 \u0111\u01b0\u1ee3c chi\u1ebft b\u1eb1ng ethanol \u2013 n\u01b0\u1edbc (coumarin \u00edt tan trong n\u01b0\u1edbc), c\u00f4 \u0111\u1eb7c v\u00e0 s\u1ea5y; nguy\u00ean li\u1ec7u th\u01b0\u1eddng ghi t\u1ef7 l\u1ec7 chi\u1ebft ho\u1eb7c h\u00e0m l\u01b0\u1ee3ng osthol.<\/p>\n<h2>Ch\u1ec9 ti\u00eau ch\u1ea5t l\u01b0\u1ee3ng n\u00ean xem<\/h2>\n<ul>\n<li>Osthol, columbianadin (HPLC); \u0111\u1ecbnh t\u00ednh theo D\u01b0\u1ee3c \u0111i\u1ec3n Vi\u1ec7t Nam.<\/li>\n<li>Kim lo\u1ea1i n\u1eb7ng, vi sinh v\u1eadt, d\u01b0 l\u01b0\u1ee3ng thu\u1ed1c b\u1ea3o v\u1ec7 th\u1ef1c v\u1eadt; \u0111\u1ed9c t\u1ed1 vi n\u1ea5m v\u1edbi d\u01b0\u1ee3c li\u1ec7u d\u1ec5 m\u1ed1c.<\/li>\n<\/ul>\n<h2>Applications<\/h2>\n<ul>\n<li>Thu\u1ed1c d\u01b0\u1ee3c li\u1ec7u, th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe (th\u01b0\u1eddng trong b\u00e0i ph\u1ed1i h\u1ee3p).<\/li>\n<li>C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n<h2>An to\u00e0n v\u00e0 l\u01b0u \u00fd<\/h2>\n<ul>\n<li>M\u1ed9t s\u1ed1 coumarin (furanocoumarin) c\u00f3 th\u1ec3 g\u00e2y nh\u1ea1y c\u1ea3m \u00e1nh s\u00e1ng.<\/li>\n<li>Ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u an to\u00e0n cho ph\u1ee5 n\u1eef mang thai, cho con b\u00fa v\u00e0 tr\u1ebb em; ng\u01b0\u1eddi \u0111ang d\u00f9ng thu\u1ed1c n\u00ean h\u1ecfi \u00fd ki\u1ebfn chuy\u00ean gia y t\u1ebf.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Chi\u1ebft xu\u1ea5t d\u01b0\u1ee3c li\u1ec7u \u0111\u01b0\u1ee3c d\u00f9ng c\u1ea3 trong thu\u1ed1c d\u01b0\u1ee3c li\u1ec7u v\u00e0 trong th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe; s\u1ea3n ph\u1ea9m thu\u1ed9c lo\u1ea1i n\u00e0o th\u00ec theo quy \u0111\u1ecbnh c\u1ee7a lo\u1ea1i \u0111\u00f3 (Lu\u1eadt D\u01b0\u1ee3c ho\u1eb7c Lu\u1eadt An to\u00e0n th\u1ef1c ph\u1ea9m, Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP). Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>B\u1ed9 Y t\u1ebf (2017). D\u01b0\u1ee3c \u0111i\u1ec3n Vi\u1ec7t Nam V, chuy\u00ean lu\u1eadn \u0110\u1ed9c ho\u1ea1t (r\u1ec5)<\/li>\n<li>Wikipedia \u2013 Angelica pubescens \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Angelica_pubescens\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Angelica_pubescens<\/a><\/li>\n<li>Wikipedia \u2013 Osthole \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Osthole\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Osthole<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Chi\u1ebft xu\u1ea5t \u0111\u1ed9c ho\u1ea1t (Angelica pubescens): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t \u0111\u1ed9c ho\u1ea1t l\u00e0 cao chi\u1ebft t\u1eeb r\u1ec5 c\u00e2y \u0111\u1ed9c ho\u1ea1t (Angelica pubescens), v\u1ecb thu\u1ed1c \u0110\u00f4ng y th\u01b0\u1eddng c\u00f3 trong c\u00e1c b\u00e0i ph\u1ed1i h\u1ee3p (v\u00ed d\u1ee5 b\u00e0i &#8220;\u0111\u1ed9c ho\u1ea1t tang k\u00fd sinh&#8221;). Nh\u00f3m ho\u1ea1t ch\u1ea5t \u0111\u1eb7c tr\u01b0ng l\u00e0 coumarin. Th\u00f4ng tin [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3407,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-794","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-doc-hoat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-doc-hoat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-doc-hoat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-doc-hoat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-doc-hoat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-doc-hoat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-doc-hoat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-doc-hoat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Chi\u1ebft xu\u1ea5t \u0111\u1ed9c ho\u1ea1t (Angelica pubescens): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t \u0111\u1ed9c ho\u1ea1t l\u00e0 cao chi\u1ebft t\u1eeb r\u1ec5 c\u00e2y \u0111\u1ed9c ho\u1ea1t (Angelica pubescens), v\u1ecb thu\u1ed1c \u0110\u00f4ng y th\u01b0\u1eddng c\u00f3 trong c\u00e1c b\u00e0i ph\u1ed1i h\u1ee3p (v\u00ed d\u1ee5 b\u00e0i &#8220;\u0111\u1ed9c ho\u1ea1t tang k\u00fd sinh&#8221;). Nh\u00f3m ho\u1ea1t ch\u1ea5t \u0111\u1eb7c tr\u01b0ng l\u00e0 coumarin. Th\u00f4ng tin&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/794","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=794"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/794\/revisions"}],"predecessor-version":[{"id":3478,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/794\/revisions\/3478"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3407"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=794"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=794"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=794"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}