{"id":788,"date":"2025-05-29T08:04:23","date_gmt":"2025-05-29T08:04:23","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-calcium-gluconate-powder-dang-bao\/"},"modified":"2026-09-28T22:27:45","modified_gmt":"2026-09-28T15:27:45","slug":"nguyen-lieu-calcium-gluconate-powder-dang-bao","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-calcium-gluconate-powder-dang-bao\/","title":{"rendered":"Calcium gluconate (calci gluconat, INS 578): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, \u1ee9ng d\u1ee5ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Calcium gluconate (calci gluconat, INS 578): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, \u1ee9ng d\u1ee5ng<\/h1>\n<p><strong>Calcium gluconate<\/strong> (calci gluconat) l\u00e0 mu\u1ed1i calci c\u1ee7a <strong>acid gluconic<\/strong>, acid h\u1eefu c\u01a1 t\u1ea1o ra khi oxy h\u00f3a glucose. Trong th\u1ef1c ph\u1ea9m, ch\u1ea5t n\u00e0y l\u00e0 ph\u1ee5 gia m\u00e3 <strong>INS 578<\/strong> v\u00e0 l\u00e0 m\u1ed9t ngu\u1ed3n calci d\u1ea1ng mu\u1ed1i h\u1eefu c\u01a1.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Calcium gluconate, calci gluconat, calci D-gluconat; E578<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c, kh\u1ed1i l\u01b0\u1ee3ng mol<\/td>\n<td>C<sub>12<\/sub>H<sub>22<\/sub>CaO<sub>14<\/sub> \u2013 430,37 g\/mol (khan); th\u01b0\u01a1ng m\u1ea1i th\u01b0\u1eddng l\u00e0 monohydrat (kho\u1ea3ng 448,4 g\/mol)<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>299-28-5<\/td>\n<\/tr>\n<tr>\n<td>H\u00e0m l\u01b0\u1ee3ng calci (t\u00ednh theo c\u00f4ng th\u1ee9c)<\/td>\n<td>kho\u1ea3ng 9,3% (khan); kho\u1ea3ng 8,9% (monohydrat)<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ch\u1ee9c n\u0103ng (TT 24\/2019)<\/td>\n<td>Ch\u1ea5t \u0111i\u1ec1u ch\u1ec9nh \u0111\u1ed9 acid, ch\u1ea5t l\u00e0m r\u1eafn ch\u1eafc, ch\u1ea5t t\u1ea1o ph\u1ee9c kim lo\u1ea1i<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>T\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>B\u1ed9t k\u1ebft tinh ho\u1eb7c h\u1ea1t m\u00e0u tr\u1eafng, kh\u00f4ng m\u00f9i, g\u1ea7n nh\u01b0 kh\u00f4ng v\u1ecb.<\/li>\n<li>Tan ch\u1eadm v\u00e0 v\u1eeba ph\u1ea3i trong n\u01b0\u1edbc l\u1ea1nh, tan t\u1ed1t h\u01a1n nhi\u1ec1u trong n\u01b0\u1edbc s\u00f4i. Dung d\u1ecbch \u0111\u1eadm \u0111\u1eb7c \u0111\u1ec3 ngu\u1ed9i d\u1ec5 qu\u00e1 b\u00e3o h\u00f2a v\u00e0 k\u1ebft tinh l\u1ea1i.<\/li>\n<li>So v\u1edbi <a href=\"\/en\/calci-carbonat\/\">calci carbonat<\/a> (kho\u1ea3ng 40% calci), h\u00e0m l\u01b0\u1ee3ng calci th\u1ea5p h\u01a1n nhi\u1ec1u, n\u00ean c\u1ea7n kh\u1ed1i l\u01b0\u1ee3ng l\u1edbn cho c\u00f9ng l\u01b0\u1ee3ng calci. B\u00f9 l\u1ea1i, mu\u1ed1i n\u00e0y tan \u0111\u01b0\u1ee3c v\u00e0 g\u1ea7n nh\u01b0 kh\u00f4ng v\u1ecb, ph\u00f9 h\u1ee3p cho \u0111\u1ed3 u\u1ed1ng, dung d\u1ecbch.<\/li>\n<\/ul>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>Glucose \u0111\u01b0\u1ee3c <strong>l\u00ean men<\/strong> (th\u01b0\u1eddng b\u1eb1ng n\u1ea5m <em>Aspergillus niger<\/em>) ho\u1eb7c oxy h\u00f3a b\u1eb1ng enzym glucose oxidase th\u00e0nh acid gluconic, r\u1ed3i trung h\u00f2a b\u1eb1ng calci carbonat ho\u1eb7c calci hydroxid. Mu\u1ed1i \u0111\u01b0\u1ee3c k\u1ebft tinh, s\u1ea5y.<\/p>\n<h2>Applications<\/h2>\n<ul>\n<li>Ph\u1ee5 gia th\u1ef1c ph\u1ea9m: \u0111i\u1ec1u ch\u1ec9nh \u0111\u1ed9 acid, l\u00e0m r\u1eafn ch\u1eafc rau qu\u1ea3 (t\u01b0\u01a1ng t\u1ef1 <a href=\"https:\/\/cpc1.vn\/en\/nguyen-lieu-calcium-lactate\/\">calci lactat<\/a>), t\u1ea1o ph\u1ee9c kim lo\u1ea1i.<\/li>\n<li>Ngu\u1ed3n calci trong \u0111\u1ed3 u\u1ed1ng, th\u1ef1c ph\u1ea9m t\u0103ng c\u01b0\u1eddng, th\u1ef1c ph\u1ea9m b\u1ed5 sung.<\/li>\n<li>D\u01b0\u1ee3c ph\u1ea9m; c\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n<ul>\n<li><strong>Vi\u1ec7t Nam<\/strong>: calci gluconat (INS 578) c\u00f3 trong danh m\u1ee5c ph\u1ee5 gia \u0111\u01b0\u1ee3c ph\u00e9p (Ph\u1ee5 l\u1ee5c 1) v\u00e0 danh m\u1ee5c ph\u1ee5 gia s\u1eed d\u1ee5ng theo GMP (Ph\u1ee5 l\u1ee5c 3) c\u1ee7a Th\u00f4ng t\u01b0 24\/2019\/TT-BYT.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Khi d\u00f9ng l\u00e0m th\u00e0nh ph\u1ea7n c\u1ee7a th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe ho\u1eb7c th\u1ef1c ph\u1ea9m b\u1ed5 sung vi ch\u1ea5t, s\u1ea3n ph\u1ea9m tu\u00e2n theo Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP v\u00e0 c\u00e1c v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf. M\u1ed9t s\u1ed1 mu\u1ed1i kho\u00e1ng c\u00f2n \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m d\u01b0\u1ee3c ch\u1ea5t; khi \u0111\u00f3 s\u1ea3n ph\u1ea9m thu\u1ed9c qu\u1ea3n l\u00fd thu\u1ed1c. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n m\u1edbi nh\u1ea5t tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Calcium gluconate \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Calcium_gluconate\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Calcium_gluconate<\/a><\/li>\n<li>Wikipedia \u2013 Gluconic acid \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Gluconic_acid\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Gluconic_acid<\/a><\/li>\n<li>Wikidata \u2013 \u0111\u1ecbnh danh h\u00f3a h\u1ecdc (CAS, c\u00f4ng th\u1ee9c) \u2014 <a href=\"https:\/\/www.wikidata.org\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.wikidata.org\/<\/a><\/li>\n<li>B\u1ed9 Y t\u1ebf \u2013 Th\u00f4ng t\u01b0 24\/2019\/TT-BYT v\u1ec1 qu\u1ea3n l\u00fd v\u00e0 s\u1eed d\u1ee5ng ph\u1ee5 gia th\u1ef1c ph\u1ea9m \u2014 <a href=\"https:\/\/vfa.gov.vn\/van-ban\/thong-tu-so-242019tt-byt-quy-dinh-ve-quan-ly-va-su-dung-phu-gia-thuc-pham.html\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/vfa.gov.vn\/van-ban\/thong-tu-so-242019tt-byt-quy-dinh-ve-quan-ly-va-su-dung-phu-gia-thuc-pham.html<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Calcium gluconate (calci gluconat, INS 578): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, \u1ee9ng d\u1ee5ng Calcium gluconate (calci gluconat) l\u00e0 mu\u1ed1i calci c\u1ee7a acid gluconic, acid h\u1eefu c\u01a1 t\u1ea1o ra khi oxy h\u00f3a glucose. Trong th\u1ef1c ph\u1ea9m, ch\u1ea5t n\u00e0y l\u00e0 ph\u1ee5 gia m\u00e3 INS 578 v\u00e0 l\u00e0 m\u1ed9t ngu\u1ed3n calci d\u1ea1ng mu\u1ed1i h\u1eefu c\u01a1. Th\u00f4ng tin nhanh T\u00ean [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2853,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-788","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calcium-gluconate.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calcium-gluconate-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calcium-gluconate-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calcium-gluconate-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calcium-gluconate-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calcium-gluconate.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calcium-gluconate.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calcium-gluconate-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Calcium gluconate (calci gluconat, INS 578): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, \u1ee9ng d\u1ee5ng Calcium gluconate (calci gluconat) l\u00e0 mu\u1ed1i calci c\u1ee7a acid gluconic, acid h\u1eefu c\u01a1 t\u1ea1o ra khi oxy h\u00f3a glucose. Trong th\u1ef1c ph\u1ea9m, ch\u1ea5t n\u00e0y l\u00e0 ph\u1ee5 gia m\u00e3 INS 578 v\u00e0 l\u00e0 m\u1ed9t ngu\u1ed3n calci d\u1ea1ng mu\u1ed1i h\u1eefu c\u01a1. Th\u00f4ng tin nhanh T\u00ean&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/788","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=788"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/788\/revisions"}],"predecessor-version":[{"id":2984,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/788\/revisions\/2984"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2853"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=788"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=788"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=788"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}