{"id":779,"date":"2025-05-29T08:00:05","date_gmt":"2025-05-29T08:00:05","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-chiet-xuat-sam-to-nu-pueraria-mirifica-powder-aber\/"},"modified":"2026-09-30T14:38:46","modified_gmt":"2026-09-30T07:38:46","slug":"nguyen-lieu-chiet-xuat-sam-to-nu-pueraria-mirifica-powder-aber","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-chiet-xuat-sam-to-nu-pueraria-mirifica-powder-aber\/","title":{"rendered":"Chi\u1ebft xu\u1ea5t s\u00e2m t\u1ed1 n\u1eef (Pueraria mirifica): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Chi\u1ebft xu\u1ea5t s\u00e2m t\u1ed1 n\u1eef (Pueraria mirifica): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng<\/h1>\n<p><strong>Chi\u1ebft xu\u1ea5t s\u00e2m t\u1ed1 n\u1eef<\/strong> l\u00e0 cao chi\u1ebft ho\u1eb7c b\u1ed9t t\u1eeb r\u1ec5 c\u1ee7 c\u00e2y <em>Pueraria mirifica<\/em> (kwao krua tr\u1eafng), c\u00e2y b\u1ea3n \u0111\u1ecba Th\u00e1i Lan, Myanmar. R\u1ec5 ch\u1ee9a <strong>phytoestrogen<\/strong> r\u1ea5t m\u1ea1nh l\u00e0 <strong>miroestrol<\/strong> v\u00e0 <strong>deoxymiroestrol<\/strong>, b\u00ean c\u1ea1nh c\u00e1c isoflavon. Lo\u00e0i n\u00e0y <strong>kh\u00e1c<\/strong> s\u1eafn d\u00e2y (<em>Pueraria montana<\/em> var. <em>lobata<\/em>) d\u00f9ng l\u00e0m b\u1ed9t s\u1eafn d\u00e2y.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>S\u00e2m t\u1ed1 n\u1eef, kwao krua tr\u1eafng (Th\u00e1i Lan), white kwao krua<\/td>\n<\/tr>\n<tr>\n<td>Lo\u00e0i<\/td>\n<td><em>Pueraria candollei var. mirifica (Airy Shaw &#038; Suvat.) Niyomdham (Pueraria mirifica)<\/em>, h\u1ecd \u0110\u1eadu (Fabaceae)<\/td>\n<\/tr>\n<tr>\n<td>B\u1ed9 ph\u1eadn d\u00f9ng<\/td>\n<td>R\u1ec5 c\u1ee7<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ho\u1ea1t ch\u1ea5t ch\u00ednh<\/td>\n<td>Phytoestrogen: miroestrol, deoxymiroestrol (chromen), isoflavon (puerarin, daidzin, genistin, daidzein, genistein)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u00e2y v\u00e0 d\u01b0\u1ee3c li\u1ec7u<\/h2>\n<p>S\u00e2m t\u1ed1 n\u1eef l\u00e0 d\u00e2y leo h\u1ecd \u0110\u1eadu, r\u1ec5 ph\u00ecnh th\u00e0nh c\u1ee7 l\u1edbn, ru\u1ed9t tr\u1eafng. C\u00e2y m\u1ecdc trong r\u1eebng r\u1ee5ng l\u00e1 v\u00f9ng B\u1eafc v\u00e0 T\u00e2y Th\u00e1i Lan; ngu\u1ed3n nguy\u00ean li\u1ec7u t\u1eeb khai th\u00e1c v\u00e0 tr\u1ed3ng.<\/p>\n<h2>Th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc<\/h2>\n<ul>\n<li><strong>Miroestrol, deoxymiroestrol<\/strong>: chromen c\u00f3 ho\u1ea1t t\u00ednh estrogen m\u1ea1nh nh\u1ea5t trong c\u00e1c phytoestrogen \u0111\u00e3 bi\u1ebft.<\/li>\n<li><strong>Isoflavon<\/strong>: puerarin, daidzin, genistin, daidzein, genistein.<\/li>\n<li>Coumestan, tinh b\u1ed9t.<\/li>\n<\/ul>\n<h2>Chi\u1ebft xu\u1ea5t v\u00e0 ti\u00eau chu\u1ea9n h\u00f3a<\/h2>\n<p>R\u1ec5 c\u1ee7 \u0111\u01b0\u1ee3c ph\u01a1i kh\u00f4, nghi\u1ec1n b\u1ed9t ho\u1eb7c chi\u1ebft b\u1eb1ng ethanol \u2013 n\u01b0\u1edbc; nguy\u00ean li\u1ec7u n\u00ean ghi h\u00e0m l\u01b0\u1ee3ng isoflavon v\u00e0 \u0111\u1eb7c bi\u1ec7t l\u00e0 miroestrol\/deoxymiroestrol. H\u00e0m l\u01b0\u1ee3ng c\u00e1c ch\u1ea5t n\u00e0y dao \u0111\u1ed9ng r\u1ea5t l\u1edbn theo v\u00f9ng, tu\u1ed5i c\u1ee7, m\u00f9a thu ho\u1ea1ch.<\/p>\n<h2>Ch\u1ec9 ti\u00eau ch\u1ea5t l\u01b0\u1ee3ng n\u00ean xem<\/h2>\n<ul>\n<li>Miroestrol, deoxymiroestrol, isoflavon (HPLC); x\u00e1c \u0111\u1ecbnh lo\u00e0i (ph\u00e2n bi\u1ec7t c\u00e1c lo\u00e0i kwao krua kh\u00e1c v\u00e0 s\u1eafn d\u00e2y).<\/li>\n<li>Kim lo\u1ea1i n\u1eb7ng, vi sinh v\u1eadt, d\u01b0 l\u01b0\u1ee3ng thu\u1ed1c b\u1ea3o v\u1ec7 th\u1ef1c v\u1eadt; \u0111\u1ed9c t\u1ed1 vi n\u1ea5m v\u1edbi d\u01b0\u1ee3c li\u1ec7u d\u1ec5 m\u1ed1c.<\/li>\n<\/ul>\n<h2>Applications<\/h2>\n<ul>\n<li>Th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe (theo quy \u0111\u1ecbnh t\u1eebng n\u01b0\u1edbc); m\u1ef9 ph\u1ea9m.<\/li>\n<li>C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n<h2>An to\u00e0n v\u00e0 l\u01b0u \u00fd<\/h2>\n<ul>\n<li>Do ho\u1ea1t t\u00ednh estrogen m\u1ea1nh, Th\u00e1i Lan gi\u1edbi h\u1ea1n l\u01b0\u1ee3ng d\u00f9ng h\u1eb1ng ng\u00e0y c\u1ee7a b\u1ed9t s\u00e2m t\u1ed1 n\u1eef; m\u1ed9t s\u1ed1 n\u01b0\u1edbc kh\u00e1c h\u1ea1n ch\u1ebf ho\u1eb7c kh\u00f4ng cho ph\u00e9p d\u00f9ng trong th\u1ef1c ph\u1ea9m.<\/li>\n<li><strong>Kh\u00f4ng d\u00f9ng<\/strong> cho ph\u1ee5 n\u1eef mang thai, cho con b\u00fa, tr\u1ebb em, ng\u01b0\u1eddi c\u00f3 b\u1ec7nh l\u00fd ph\u1ee5 thu\u1ed9c hormon (v\u00ed d\u1ee5 ung th\u01b0 v\u00fa, u x\u01a1 t\u1eed cung); ng\u01b0\u1eddi \u0111ang d\u00f9ng thu\u1ed1c n\u1ed9i ti\u1ebft c\u1ea7n h\u1ecfi \u00fd ki\u1ebfn b\u00e1c s\u0129.<\/li>\n<\/ul>\n<p><!--my-pham--><\/p>\n<h2>In Cosmetics<\/h2>\n<p>Ngo\u00e0i d\u01b0\u1ee3c ph\u1ea9m v\u00e0 th\u1ef1c ph\u1ea9m, nguy\u00ean li\u1ec7u t\u1eeb lo\u00e0i n\u00e0y c\u00f2n \u0111\u01b0\u1ee3c d\u00f9ng trong m\u1ef9 ph\u1ea9m d\u01b0\u1edbi c\u00e1c t\u00ean INCI sau (ch\u1ee9c n\u0103ng theo c\u01a1 s\u1edf d\u1eef li\u1ec7u CosIng c\u1ee7a \u1ee6y ban ch\u00e2u \u00c2u):<\/p>\n<table>\n<thead>\n<tr>\n<th>T\u00ean INCI<\/th>\n<th>D\u1ea1ng nguy\u00ean li\u1ec7u<\/th>\n<th>Ch\u1ee9c n\u0103ng (CosIng)<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Pueraria Mirifica Root Extract<\/td>\n<td>chi\u1ebft xu\u1ea5t b\u1eb1ng dung m\u00f4i (th\u01b0\u1eddng l\u00e0 n\u01b0\u1edbc, glycol ho\u1eb7c ethanol), sau \u0111\u00f3 pha lo\u00e3ng trong dung m\u00f4i mang<\/td>\n<td>d\u01b0\u1ee1ng da<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Theo CosIng, c\u00e1c t\u00ean INCI tr\u00ean kh\u00f4ng thu\u1ed9c ph\u1ee5 l\u1ee5c ch\u1ea5t c\u1ea5m (Annex II) hay h\u1ea1n ch\u1ebf (Annex III) c\u1ee7a EU t\u1ea1i th\u1eddi \u0111i\u1ec3m vi\u1ebft b\u00e0i; ph\u1ee5 l\u1ee5c c\u1ee7a Hi\u1ec7p \u0111\u1ecbnh m\u1ef9 ph\u1ea9m ASEAN \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadt theo danh m\u1ee5c n\u00e0y. T\u1ea1i Vi\u1ec7t Nam, m\u1ef9 ph\u1ea9m qu\u1ea3n l\u00fd theo Th\u00f4ng t\u01b0 06\/2011\/TT-BYT; t\u00ednh n\u0103ng c\u00f4ng b\u1ed1 ph\u1ea3i theo H\u01b0\u1edbng d\u1eabn c\u00f4ng b\u1ed1 t\u00ednh n\u0103ng m\u1ef9 ph\u1ea9m ASEAN, kh\u00f4ng \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 c\u00f4ng d\u1ee5ng nh\u01b0 thu\u1ed1c.<\/p>\n<p><!--\/my-pham--><\/p>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Khi d\u00f9ng l\u00e0m th\u00e0nh ph\u1ea7n c\u1ee7a th\u1ef1c ph\u1ea9m ho\u1eb7c th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe, s\u1ea3n ph\u1ea9m tu\u00e2n theo Lu\u1eadt An to\u00e0n th\u1ef1c ph\u1ea9m, Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP v\u00e0 c\u00e1c v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n m\u1edbi nh\u1ea5t tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Pueraria mirifica \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Pueraria_mirifica\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Pueraria_mirifica<\/a><\/li>\n<li>Wikipedia \u2013 Miroestrol \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Miroestrol\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Miroestrol<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Chi\u1ebft xu\u1ea5t s\u00e2m t\u1ed1 n\u1eef (Pueraria mirifica): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t s\u00e2m t\u1ed1 n\u1eef l\u00e0 cao chi\u1ebft ho\u1eb7c b\u1ed9t t\u1eeb r\u1ec5 c\u1ee7 c\u00e2y Pueraria mirifica (kwao krua tr\u1eafng), c\u00e2y b\u1ea3n \u0111\u1ecba Th\u00e1i Lan, Myanmar. R\u1ec5 ch\u1ee9a phytoestrogen r\u1ea5t m\u1ea1nh l\u00e0 miroestrol v\u00e0 deoxymiroestrol, b\u00ean c\u1ea1nh c\u00e1c isoflavon. Lo\u00e0i n\u00e0y kh\u00e1c [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3469,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-779","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-sam-to-nu.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-sam-to-nu-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-sam-to-nu-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-sam-to-nu-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-sam-to-nu-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-sam-to-nu.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-sam-to-nu.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-sam-to-nu-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Chi\u1ebft xu\u1ea5t s\u00e2m t\u1ed1 n\u1eef (Pueraria mirifica): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t s\u00e2m t\u1ed1 n\u1eef l\u00e0 cao chi\u1ebft ho\u1eb7c b\u1ed9t t\u1eeb r\u1ec5 c\u1ee7 c\u00e2y Pueraria mirifica (kwao krua tr\u1eafng), c\u00e2y b\u1ea3n \u0111\u1ecba Th\u00e1i Lan, Myanmar. R\u1ec5 ch\u1ee9a phytoestrogen r\u1ea5t m\u1ea1nh l\u00e0 miroestrol v\u00e0 deoxymiroestrol, b\u00ean c\u1ea1nh c\u00e1c isoflavon. Lo\u00e0i n\u00e0y kh\u00e1c&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/779","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=779"}],"version-history":[{"count":3,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/779\/revisions"}],"predecessor-version":[{"id":4654,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/779\/revisions\/4654"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3469"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=779"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=779"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=779"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}