{"id":766,"date":"2025-05-29T07:52:37","date_gmt":"2025-05-29T07:52:37","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-vitamin-a-palmitate-dang-dau\/"},"modified":"2026-09-28T20:59:44","modified_gmt":"2026-09-28T13:59:44","slug":"nguyen-lieu-vitamin-a-palmitate-dang-dau","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-vitamin-a-palmitate-dang-dau\/","title":{"rendered":"Retinyl palmitate (vitamin A palmitat): c\u1ea5u t\u1ea1o, \u0111\u01a1n v\u1ecb, \u0111\u1ed9 b\u1ec1n v\u00e0 quy \u0111\u1ecbnh"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Retinyl palmitate (vitamin A palmitat): c\u1ea5u t\u1ea1o, \u0111\u01a1n v\u1ecb, \u0111\u1ed9 b\u1ec1n v\u00e0 quy \u0111\u1ecbnh<\/h1>\n<p><strong>Retinyl palmitate<\/strong> (vitamin A palmitat) l\u00e0 ester c\u1ee7a <strong>retinol<\/strong> (vitamin A) v\u1edbi acid palmitic. \u0110\u00e2y l\u00e0 d\u1ea1ng l\u01b0u tr\u1eef vitamin A t\u1ef1 nhi\u00ean trong gan \u0111\u1ed9ng v\u1eadt v\u00e0 l\u00e0 d\u1ea1ng th\u01b0\u01a1ng m\u1ea1i ph\u1ed5 bi\u1ebfn nh\u1ea5t trong th\u1ef1c ph\u1ea9m, s\u1eefa c\u00f4ng th\u1ee9c v\u00e0 m\u1ef9 ph\u1ea9m, v\u00ec <strong>b\u1ec1n h\u01a1n retinol t\u1ef1 do<\/strong> nhi\u1ec1u.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Retinyl palmitate, vitamin A palmitat, retinol hexadecanoat<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c, kh\u1ed1i l\u01b0\u1ee3ng mol<\/td>\n<td>C<sub>36<\/sub>H<sub>60<\/sub>O<sub>2<\/sub> \u2013 524,87 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>79-81-2<\/td>\n<\/tr>\n<tr>\n<td>Quy \u0111\u1ed5i<\/td>\n<td>1 IU vitamin A = 0,3 \u00b5g retinol \u2248 0,55 \u00b5g retinyl palmitate; 1 \u00b5g retinol t\u01b0\u01a1ng \u0111\u01b0\u01a1ng (RE) \u2248 1,83 \u00b5g retinyl palmitate<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u1ea5u t\u1ea1o v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>Ph\u1ea7n retinol c\u00f3 chu\u1ed7i <strong>b\u1ed1n li\u00ean k\u1ebft \u0111\u00f4i li\u00ean h\u1ee3p<\/strong> n\u1ed1i v\u1edbi v\u00f2ng \u03b2-ionon. Chu\u1ed7i li\u00ean h\u1ee3p n\u00e0y l\u00e0m vitamin A d\u1ec5 b\u1ecb oxy h\u00f3a v\u00e0 \u0111\u1ed3ng ph\u00e2n h\u00f3a b\u1edfi \u00e1nh s\u00e1ng, nhi\u1ec7t, oxy v\u00e0 acid.<\/li>\n<li>G\u1eafn acid palmitic v\u00e0o nh\u00f3m \u2013OH gi\u00fap ph\u00e2n t\u1eed b\u1ec1n h\u01a1n, nh\u01b0ng v\u1eabn c\u1ea7n b\u1ea3o v\u1ec7. Nguy\u00ean li\u1ec7u th\u01b0\u01a1ng m\u1ea1i th\u01b0\u1eddng c\u00f3 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a (tocopherol, BHT) \u0111i k\u00e8m.<\/li>\n<li>D\u1ea1ng tinh khi\u1ebft l\u00e0 ch\u1ea5t r\u1eafn ho\u1eb7c d\u1ea7u s\u00e1nh m\u00e0u v\u00e0ng nh\u1ea1t, kh\u00f4ng tan trong n\u01b0\u1edbc, tan trong d\u1ea7u.<\/li>\n<\/ul>\n<h2>D\u1ea1ng nguy\u00ean li\u1ec7u<\/h2>\n<ul>\n<li><strong>D\u1ea1ng d\u1ea7u<\/strong> (v\u00ed d\u1ee5 1,0 ho\u1eb7c 1,7 tri\u1ec7u IU\/g), c\u00f3 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a: d\u00f9ng cho vi\u00ean nang m\u1ec1m, d\u1ea7u \u0103n t\u0103ng c\u01b0\u1eddng, m\u1ef9 ph\u1ea9m.<\/li>\n<li><strong>D\u1ea1ng b\u1ed9t vi nang<\/strong> (bao trong gelatin, g\u00f4m arabic ho\u1eb7c tinh b\u1ed9t bi\u1ebfn t\u00ednh): d\u00f9ng cho vi\u00ean n\u00e9n, b\u1ed9t pha, s\u1eefa b\u1ed9t.<\/li>\n<\/ul>\n<p>H\u00e0m l\u01b0\u1ee3ng th\u1ef1c t\u1ebf theo COA c\u1ee7a t\u1eebng l\u00f4; n\u00ean t\u00ednh d\u01b0 theo d\u1eef li\u1ec7u \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh c\u1ee7a ch\u00ednh s\u1ea3n ph\u1ea9m.<\/p>\n<h2>Applications<\/h2>\n<ul>\n<li>Th\u1ef1c ph\u1ea9m b\u1ed5 sung; th\u1ef1c ph\u1ea9m t\u0103ng c\u01b0\u1eddng vi ch\u1ea5t (d\u1ea7u \u0103n, s\u1eefa, b\u1ed9t m\u00ec); s\u1eefa c\u00f4ng th\u1ee9c; th\u1ee9c \u0103n ch\u0103n nu\u00f4i.<\/li>\n<li>M\u1ef9 ph\u1ea9m ch\u0103m s\u00f3c da.<\/li>\n<\/ul>\n<h2>An to\u00e0n v\u00e0 quy \u0111\u1ecbnh<\/h2>\n<ul>\n<li>Vitamin A d\u1ea1ng retinol v\u00e0 ester t\u00edch l\u0169y trong c\u01a1 th\u1ec3. L\u01b0\u1ee3ng v\u01b0\u1ee3t qu\u00e1 m\u1ee9c ti\u00eau th\u1ee5 t\u1ed1i \u0111a ch\u1ea5p nh\u1eadn \u0111\u01b0\u1ee3c (UL) g\u00e2y \u0111\u1ed9c, v\u00e0 <strong>l\u01b0\u1ee3ng cao trong thai k\u1ef3 c\u00f3 nguy c\u01a1 g\u00e2y d\u1ecb t\u1eadt thai nhi<\/strong>. V\u00ec v\u1eady c\u00e1c c\u01a1 quan qu\u1ea3n l\u00fd \u0111\u1eb7t gi\u1edbi h\u1ea1n ch\u1eb7t cho s\u1ea3n ph\u1ea9m d\u00e0nh cho ph\u1ee5 n\u1eef mang thai.<\/li>\n<li><strong>M\u1ef9 ph\u1ea9m t\u1ea1i EU<\/strong>: Quy \u0111\u1ecbnh (EU) 2024\/996 gi\u1edbi h\u1ea1n retinol, retinyl acetat v\u00e0 retinyl palmitat \u1edf t\u1ed1i \u0111a <strong>0,05% RE<\/strong> trong s\u1eefa d\u01b0\u1ee1ng th\u1ec3 v\u00e0 <strong>0,3% RE<\/strong> trong c\u00e1c s\u1ea3n ph\u1ea9m kh\u00e1c, k\u00e8m c\u1ea3nh b\u00e1o tr\u00ean nh\u00e3n. \u00c1p d\u1ee5ng v\u1edbi s\u1ea3n ph\u1ea9m m\u1edbi t\u1eeb 01\/11\/2025 v\u00e0 m\u1ecdi s\u1ea3n ph\u1ea9m t\u1eeb 01\/11\/2027.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Khi d\u00f9ng l\u00e0m th\u00e0nh ph\u1ea7n c\u1ee7a th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe ho\u1eb7c th\u1ef1c ph\u1ea9m t\u0103ng c\u01b0\u1eddng vi ch\u1ea5t, s\u1ea3n ph\u1ea9m tu\u00e2n theo Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP v\u00e0 c\u00e1c v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf, k\u1ec3 c\u1ea3 quy \u0111\u1ecbnh v\u1ec1 h\u00e0m l\u01b0\u1ee3ng vitamin so v\u1edbi nhu c\u1ea7u khuy\u1ebfn ngh\u1ecb. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n m\u1edbi nh\u1ea5t tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>B\u1ea3o qu\u1ea3n<\/h2>\n<p>Tr\u00e1nh \u00e1nh s\u00e1ng, nhi\u1ec7t v\u00e0 kh\u00f4ng kh\u00ed. Bao b\u00ec m\u1edf r\u1ed3i n\u00ean th\u1ed5i kh\u00ed nit\u01a1 tr\u01b0\u1edbc khi \u0111\u00f3ng l\u1ea1i, ho\u1eb7c d\u00f9ng h\u1ebft s\u1edbm.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Retinyl palmitate \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Retinyl_palmitate\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Retinyl_palmitate<\/a><\/li>\n<li>Wikidata \u2013 \u0111\u1ecbnh danh h\u00f3a h\u1ecdc (CAS, c\u00f4ng th\u1ee9c) \u2014 <a href=\"https:\/\/www.wikidata.org\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.wikidata.org\/<\/a><\/li>\n<li>Quy \u0111\u1ecbnh (EU) 2024\/996 s\u1eeda \u0111\u1ed5i Ph\u1ee5 l\u1ee5c Quy \u0111\u1ecbnh m\u1ef9 ph\u1ea9m (EC) 1223\/2009 \u2013 t\u00f3m t\u1eaft c\u1ee7a UL Solutions \u2014 <a href=\"https:\/\/www.ul.com\/news\/eu-updates-annexes-ii-iii-v-and-vi-cosmetics-regulation\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.ul.com\/news\/eu-updates-annexes-ii-iii-v-and-vi-cosmetics-regulation<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Retinyl palmitate (vitamin A palmitat): c\u1ea5u t\u1ea1o, \u0111\u01a1n v\u1ecb, \u0111\u1ed9 b\u1ec1n v\u00e0 quy \u0111\u1ecbnh Retinyl palmitate (vitamin A palmitat) l\u00e0 ester c\u1ee7a retinol (vitamin A) v\u1edbi acid palmitic. \u0110\u00e2y l\u00e0 d\u1ea1ng l\u01b0u tr\u1eef vitamin A t\u1ef1 nhi\u00ean trong gan \u0111\u1ed9ng v\u1eadt v\u00e0 l\u00e0 d\u1ea1ng th\u01b0\u01a1ng m\u1ea1i ph\u1ed5 bi\u1ebfn nh\u1ea5t trong th\u1ef1c ph\u1ea9m, s\u1eefa c\u00f4ng th\u1ee9c [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2963,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-766","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitamin-a-palmitate.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitamin-a-palmitate-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitamin-a-palmitate-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitamin-a-palmitate-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitamin-a-palmitate-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitamin-a-palmitate.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitamin-a-palmitate.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/vitamin-a-palmitate-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Retinyl palmitate (vitamin A palmitat): c\u1ea5u t\u1ea1o, \u0111\u01a1n v\u1ecb, \u0111\u1ed9 b\u1ec1n v\u00e0 quy \u0111\u1ecbnh Retinyl palmitate (vitamin A palmitat) l\u00e0 ester c\u1ee7a retinol (vitamin A) v\u1edbi acid palmitic. \u0110\u00e2y l\u00e0 d\u1ea1ng l\u01b0u tr\u1eef vitamin A t\u1ef1 nhi\u00ean trong gan \u0111\u1ed9ng v\u1eadt v\u00e0 l\u00e0 d\u1ea1ng th\u01b0\u01a1ng m\u1ea1i ph\u1ed5 bi\u1ebfn nh\u1ea5t trong th\u1ef1c ph\u1ea9m, s\u1eefa c\u00f4ng th\u1ee9c&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/766","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=766"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/766\/revisions"}],"predecessor-version":[{"id":3096,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/766\/revisions\/3096"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2963"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=766"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=766"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=766"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}