{"id":745,"date":"2025-05-29T07:43:24","date_gmt":"2025-05-29T07:43:24","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-vitamin-pp-nicotinamide-2\/"},"modified":"2026-09-28T20:56:28","modified_gmt":"2026-09-28T13:56:28","slug":"nguyen-lieu-vitamin-pp-nicotinamide-2","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-vitamin-pp-nicotinamide-2\/","title":{"rendered":"Nicotinamide (niacinamide, vitamin B3): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, \u1ee9ng d\u1ee5ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Nicotinamide (niacinamide, vitamin B3): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, \u1ee9ng d\u1ee5ng<\/h1>\n<p><strong>Nicotinamide<\/strong> (c\u00f2n g\u1ecdi <strong>niacinamide<\/strong>, <strong>vitamin PP<\/strong>) l\u00e0 m\u1ed9t trong hai d\u1ea1ng c\u1ee7a <strong>vitamin B3<\/strong> (niacin), d\u1ea1ng c\u00f2n l\u1ea1i l\u00e0 acid nicotinic. Trong c\u01a1 th\u1ec3, nicotinamide l\u00e0 th\u00e0nh ph\u1ea7n c\u1ee7a coenzym NAD<sup>+<\/sup> v\u00e0 NADP<sup>+<\/sup>, tham gia h\u00e0ng tr\u0103m ph\u1ea3n \u1ee9ng oxy h\u00f3a \u2013 kh\u1eed.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Nicotinamide, niacinamide, pyridin-3-carboxamid, vitamin PP<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c, kh\u1ed1i l\u01b0\u1ee3ng mol<\/td>\n<td>C<sub>6<\/sub>H<sub>6<\/sub>N<sub>2<\/sub>O \u2013 122,13 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>98-92-0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u1ea5u t\u1ea1o v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>L\u00e0 amid c\u1ee7a acid nicotinic (acid pyridin-3-carboxylic). Hai d\u1ea1ng c\u00f3 c\u00f9ng ho\u1ea1t t\u00ednh vitamin, nh\u01b0ng kh\u00e1c nhau \u1edf m\u1ed9t \u0111i\u1ec3m quan tr\u1ecdng: acid nicotinic li\u1ec1u cao g\u00e2y <strong>\u0111\u1ecf b\u1eebng da<\/strong> (flushing), c\u00f2n nicotinamide th\u00ec kh\u00f4ng.<\/li>\n<li>B\u1ed9t k\u1ebft tinh m\u00e0u tr\u1eafng, <strong>tan r\u1ea5t t\u1ed1t trong n\u01b0\u1edbc<\/strong>, tan trong ethanol v\u00e0 glycerin.<\/li>\n<li>B\u1ec1n v\u1edbi nhi\u1ec7t, \u00e1nh s\u00e1ng v\u00e0 kh\u00f4ng kh\u00ed \u1edf d\u1ea1ng kh\u00f4; trong dung d\u1ecbch acid ho\u1eb7c ki\u1ec1m m\u1ea1nh, khi \u0111un l\u00e2u c\u00f3 th\u1ec3 b\u1ecb th\u1ee7y ph\u00e2n th\u00e0nh acid nicotinic.<\/li>\n<\/ul>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>Nicotinamide \u0111\u01b0\u1ee3c <strong>t\u1ed5ng h\u1ee3p h\u00f3a h\u1ecdc<\/strong>: 3-methylpyridin \u0111\u01b0\u1ee3c chuy\u1ec3n th\u00e0nh 3-cyanopyridin, sau \u0111\u00f3 th\u1ee7y ph\u00e2n c\u00f3 ki\u1ec3m so\u00e1t (th\u01b0\u1eddng b\u1eb1ng enzym nitril hydratase) th\u00e0nh nicotinamide.<\/p>\n<h2>Applications<\/h2>\n<ul>\n<li>Th\u1ef1c ph\u1ea9m b\u1ed5 sung, vi\u00ean \u0111a vitamin; th\u1ef1c ph\u1ea9m t\u0103ng c\u01b0\u1eddng (b\u1ed9t m\u00ec, ng\u0169 c\u1ed1c); th\u1ee9c \u0103n ch\u0103n nu\u00f4i.<\/li>\n<li><strong>Cosmetics<\/strong>: niacinamide l\u00e0 ho\u1ea1t ch\u1ea5t ph\u1ed5 bi\u1ebfn trong s\u1ea3n ph\u1ea9m ch\u0103m s\u00f3c da, th\u01b0\u1eddng \u1edf n\u1ed3ng \u0111\u1ed9 v\u00e0i ph\u1ea7n tr\u0103m, nh\u1edd tan t\u1ed1t trong n\u01b0\u1edbc, b\u1ec1n v\u00e0 t\u01b0\u01a1ng h\u1ee3p v\u1edbi nhi\u1ec1u th\u00e0nh ph\u1ea7n.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Khi d\u00f9ng l\u00e0m th\u00e0nh ph\u1ea7n c\u1ee7a th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe ho\u1eb7c th\u1ef1c ph\u1ea9m t\u0103ng c\u01b0\u1eddng vi ch\u1ea5t, s\u1ea3n ph\u1ea9m tu\u00e2n theo Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP v\u00e0 c\u00e1c v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf, k\u1ec3 c\u1ea3 quy \u0111\u1ecbnh v\u1ec1 h\u00e0m l\u01b0\u1ee3ng vitamin so v\u1edbi nhu c\u1ea7u khuy\u1ebfn ngh\u1ecb. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n m\u1edbi nh\u1ea5t tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Nicotinamide \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Nicotinamide\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Nicotinamide<\/a><\/li>\n<li>Wikidata \u2013 \u0111\u1ecbnh danh h\u00f3a h\u1ecdc (CAS, c\u00f4ng th\u1ee9c) \u2014 <a href=\"https:\/\/www.wikidata.org\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.wikidata.org\/<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Nicotinamide (niacinamide, vitamin B3): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, \u1ee9ng d\u1ee5ng Nicotinamide (c\u00f2n g\u1ecdi niacinamide, vitamin PP) l\u00e0 m\u1ed9t trong hai d\u1ea1ng c\u1ee7a vitamin B3 (niacin), d\u1ea1ng c\u00f2n l\u1ea1i l\u00e0 acid nicotinic. Trong c\u01a1 th\u1ec3, nicotinamide l\u00e0 th\u00e0nh ph\u1ea7n c\u1ee7a coenzym NAD+ v\u00e0 NADP+, tham gia h\u00e0ng tr\u0103m ph\u1ea3n \u1ee9ng oxy h\u00f3a \u2013 kh\u1eed. Th\u00f4ng tin [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2942,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-745","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nicotinamide.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nicotinamide-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nicotinamide-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nicotinamide-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nicotinamide-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nicotinamide.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nicotinamide.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nicotinamide-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Nicotinamide (niacinamide, vitamin B3): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, \u1ee9ng d\u1ee5ng Nicotinamide (c\u00f2n g\u1ecdi niacinamide, vitamin PP) l\u00e0 m\u1ed9t trong hai d\u1ea1ng c\u1ee7a vitamin B3 (niacin), d\u1ea1ng c\u00f2n l\u1ea1i l\u00e0 acid nicotinic. Trong c\u01a1 th\u1ec3, nicotinamide l\u00e0 th\u00e0nh ph\u1ea7n c\u1ee7a coenzym NAD+ v\u00e0 NADP+, tham gia h\u00e0ng tr\u0103m ph\u1ea3n \u1ee9ng oxy h\u00f3a \u2013 kh\u1eed. Th\u00f4ng tin&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/745","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=745"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/745\/revisions"}],"predecessor-version":[{"id":3075,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/745\/revisions\/3075"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2942"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=745"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=745"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=745"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}