{"id":738,"date":"2025-05-29T07:40:28","date_gmt":"2025-05-29T07:40:28","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-l-arginine-hcl-tq\/"},"modified":"2026-09-28T20:53:35","modified_gmt":"2026-09-28T13:53:35","slug":"nguyen-lieu-l-arginine-hcl-tq","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-l-arginine-hcl-tq\/","title":{"rendered":"L-Arginine (arginin): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, s\u1ea3n xu\u1ea5t v\u00e0 \u1ee9ng d\u1ee5ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">L-Arginine (arginin): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, s\u1ea3n xu\u1ea5t v\u00e0 \u1ee9ng d\u1ee5ng<\/h1>\n<p><strong>L-Arginine<\/strong> (arginin) l\u00e0 m\u1ed9t trong 20 acid amin c\u1ea5u t\u1ea1o n\u00ean protein. Arginin c\u00f3 t\u00ednh base m\u1ea1nh nh\u1ea5t trong nh\u00f3m n\u00e0y nh\u1edd <strong>nh\u00f3m guanidino<\/strong> \u1edf cu\u1ed1i m\u1ea1ch b\u00ean. Tr\u00ean th\u1ecb tr\u01b0\u1eddng nguy\u00ean li\u1ec7u, arginin c\u00f3 ba d\u1ea1ng ch\u00ednh: acid amin t\u1ef1 do, mu\u1ed1i <strong>hydroclorid<\/strong> (L-arginine HCl) v\u00e0 mu\u1ed1i v\u1edbi acid aspartic (L-arginine L-aspartate).<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>L-Arginine, arginin, acid (S)-2-amino-5-guanidinopentanoic; k\u00fd hi\u1ec7u Arg, R<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c, kh\u1ed1i l\u01b0\u1ee3ng mol<\/td>\n<td>C<sub>6<\/sub>H<sub>14<\/sub>N<sub>4<\/sub>O<sub>2<\/sub> \u2013 174,20 g\/mol; d\u1ea1ng HCl: C<sub>6<\/sub>H<sub>15<\/sub>ClN<sub>4<\/sub>O<sub>2<\/sub> \u2013 210,67 g\/mol; d\u1ea1ng L-aspartat: C<sub>10<\/sub>H<sub>21<\/sub>N<sub>5<\/sub>O<sub>6<\/sub> \u2013 307,31 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>74-79-3 (L-arginine); 1119-34-2 (L-arginine hydroclorid)<\/td>\n<\/tr>\n<tr>\n<td>H\u00e0m l\u01b0\u1ee3ng arginin (t\u00ednh theo c\u00f4ng th\u1ee9c)<\/td>\n<td>kho\u1ea3ng 82,7% trong d\u1ea1ng HCl; kho\u1ea3ng 56,7% trong d\u1ea1ng L-aspartat<\/td>\n<\/tr>\n<tr>\n<td>Ph\u00e2n lo\u1ea1i dinh d\u01b0\u1ee1ng<\/td>\n<td>Acid amin b\u00e1n thi\u1ebft y\u1ebfu (c\u01a1 th\u1ec3 ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh t\u1ef1 t\u1ed5ng h\u1ee3p \u0111\u01b0\u1ee3c, nhu c\u1ea7u t\u0103ng trong m\u1ed9t s\u1ed1 giai \u0111o\u1ea1n)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u1ea5u t\u1ea1o v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>M\u1ea1ch b\u00ean g\u1ed3m ba nh\u00f3m CH<sub>2<\/sub> n\u1ed1i v\u1edbi nh\u00f3m guanidino. Nh\u00f3m n\u00e0y h\u1ea7u nh\u01b0 lu\u00f4n mang \u0111i\u1ec7n d\u01b0\u01a1ng \u1edf pH sinh l\u00fd, n\u00ean arginin l\u00e0 acid amin ki\u1ec1m.<\/li>\n<li>D\u1ea1ng t\u1ef1 do l\u00e0 b\u1ed9t k\u1ebft tinh m\u00e0u tr\u1eafng, tan t\u1ed1t trong n\u01b0\u1edbc; dung d\u1ecbch c\u00f3 pH ki\u1ec1m v\u00e0 v\u1ecb \u0111\u1eafng. Mu\u1ed1i hydroclorid cho dung d\u1ecbch g\u1ea7n trung t\u00ednh, v\u1ecb b\u1edbt g\u1eaft h\u01a1n, n\u00ean d\u1ec5 d\u00f9ng trong c\u00f4ng th\u1ee9c h\u01a1n.<\/li>\n<li>Mu\u1ed1i L-arginine L-aspartate gh\u00e9p m\u1ed9t acid amin ki\u1ec1m (arginin) v\u1edbi m\u1ed9t acid amin acid (aspartic), cho dung d\u1ecbch g\u1ea7n trung t\u00ednh m\u00e0 kh\u00f4ng c\u1ea7n ion clorid.<\/li>\n<\/ul>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>L-Arginine c\u00f4ng nghi\u1ec7p ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1eb1ng <strong>l\u00ean men vi sinh v\u1eadt<\/strong> (c\u00e1c ch\u1ee7ng <em>Corynebacterium glutamicum<\/em> \u0111\u01b0\u1ee3c c\u1ea3i bi\u1ebfn) t\u1eeb ngu\u1ed3n \u0111\u01b0\u1eddng. Sau l\u00ean men, arginin \u0111\u01b0\u1ee3c t\u00e1ch b\u1eb1ng trao \u0111\u1ed5i ion, r\u1ed3i k\u1ebft tinh \u1edf d\u1ea1ng t\u1ef1 do ho\u1eb7c chuy\u1ec3n th\u00e0nh mu\u1ed1i hydroclorid. Tr\u01b0\u1edbc khi c\u00f3 l\u00ean men, arginin \u0111\u01b0\u1ee3c t\u00e1ch t\u1eeb d\u1ecbch th\u1ee7y ph\u00e2n protein.<\/p>\n<h2>Vai tr\u00f2 sinh h\u00f3a<\/h2>\n<p>Trong c\u01a1 th\u1ec3, arginin tham gia chu tr\u00ecnh ur\u00ea (chuy\u1ec3n amoniac th\u00e0nh ur\u00ea \u0111\u1ec3 th\u1ea3i ra ngo\u00e0i) v\u00e0 l\u00e0 ti\u1ec1n ch\u1ea5t sinh t\u1ed5ng h\u1ee3p c\u1ee7a nitric oxid (NO), creatin, ornithin v\u00e0 polyamin. \u0110\u00e2y l\u00e0 ki\u1ebfn th\u1ee9c sinh h\u00f3a n\u1ec1n; c\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/p>\n<h2>Applications<\/h2>\n<ul>\n<li>Th\u1ef1c ph\u1ea9m b\u1ed5 sung, th\u1ef1c ph\u1ea9m dinh d\u01b0\u1ee1ng y h\u1ecdc v\u00e0 \u0111\u1ed3 u\u1ed1ng th\u1ec3 thao, th\u01b0\u1eddng \u1edf d\u1ea1ng HCl ho\u1eb7c aspartat.<\/li>\n<li>Dinh d\u01b0\u1ee1ng l\u00e2m s\u00e0ng: th\u00e0nh ph\u1ea7n c\u1ee7a dung d\u1ecbch acid amin.<\/li>\n<li>M\u1ef9 ph\u1ea9m: ch\u1ea5t \u0111i\u1ec1u ch\u1ec9nh pH, ch\u1ea5t d\u01b0\u1ee1ng da, t\u00f3c.<\/li>\n<li>Th\u1ee9c \u0103n ch\u0103n nu\u00f4i, \u0111\u1eb7c bi\u1ec7t cho gia c\u1ea7m.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n<ul>\n<li><strong>Hoa K\u1ef3<\/strong>: 21 CFR 172.320 cho ph\u00e9p L-arginine l\u00e0m ph\u1ee5 gia \u0111\u1ec3 c\u1ea3i thi\u1ec7n ch\u1ea5t l\u01b0\u1ee3ng protein trong th\u1ef1c ph\u1ea9m, t\u1ed1i \u0111a 6,6% kh\u1ed1i l\u01b0\u1ee3ng protein to\u00e0n ph\u1ea7n, \u1edf d\u1ea1ng t\u1ef1 do ho\u1eb7c mu\u1ed1i hydroclorid, natri, kali.<\/li>\n<li><strong>Vi\u1ec7t Nam<\/strong>: khi d\u00f9ng trong th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe, s\u1ea3n ph\u1ea9m tu\u00e2n theo Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP v\u00e0 c\u00e1c v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf.<\/li>\n<\/ul>\n<h2>B\u1ea3o qu\u1ea3n<\/h2>\n<p>\u0110\u1ec3 n\u01a1i kh\u00f4, tho\u00e1ng, trong bao b\u00ec k\u00edn. D\u1ea1ng t\u1ef1 do c\u00f3 t\u00ednh ki\u1ec1m v\u00e0 d\u1ec5 h\u00fat CO<sub>2<\/sub> t\u1eeb kh\u00f4ng kh\u00ed khi \u0111\u1ec3 h\u1edf, n\u00ean \u0111\u00f3ng k\u00edn sau m\u1ed7i l\u1ea7n d\u00f9ng.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Arginine \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Arginine\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Arginine<\/a><\/li>\n<li>Wikidata \u2013 L-arginine hydrochloride (CAS 1119-34-2) \u2014 <a href=\"https:\/\/www.wikidata.org\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.wikidata.org\/<\/a><\/li>\n<li>U.S. FDA \u2013 21 CFR 172.320 Amino acids \u2014 <a href=\"https:\/\/www.law.cornell.edu\/cfr\/text\/21\/172.320\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.law.cornell.edu\/cfr\/text\/21\/172.320<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>L-Arginine (arginin): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, s\u1ea3n xu\u1ea5t v\u00e0 \u1ee9ng d\u1ee5ng L-Arginine (arginin) l\u00e0 m\u1ed9t trong 20 acid amin c\u1ea5u t\u1ea1o n\u00ean protein. Arginin c\u00f3 t\u00ednh base m\u1ea1nh nh\u1ea5t trong nh\u00f3m n\u00e0y nh\u1edd nh\u00f3m guanidino \u1edf cu\u1ed1i m\u1ea1ch b\u00ean. Tr\u00ean th\u1ecb tr\u01b0\u1eddng nguy\u00ean li\u1ec7u, arginin c\u00f3 ba d\u1ea1ng ch\u00ednh: acid amin t\u1ef1 do, mu\u1ed1i hydroclorid [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2924,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-738","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/l-arginine.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/l-arginine-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/l-arginine-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/l-arginine-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/l-arginine-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/l-arginine.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/l-arginine.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/l-arginine-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"L-Arginine (arginin): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, s\u1ea3n xu\u1ea5t v\u00e0 \u1ee9ng d\u1ee5ng L-Arginine (arginin) l\u00e0 m\u1ed9t trong 20 acid amin c\u1ea5u t\u1ea1o n\u00ean protein. Arginin c\u00f3 t\u00ednh base m\u1ea1nh nh\u1ea5t trong nh\u00f3m n\u00e0y nh\u1edd nh\u00f3m guanidino \u1edf cu\u1ed1i m\u1ea1ch b\u00ean. Tr\u00ean th\u1ecb tr\u01b0\u1eddng nguy\u00ean li\u1ec7u, arginin c\u00f3 ba d\u1ea1ng ch\u00ednh: acid amin t\u1ef1 do, mu\u1ed1i hydroclorid&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/738","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=738"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/738\/revisions"}],"predecessor-version":[{"id":3057,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/738\/revisions\/3057"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2924"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=738"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=738"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=738"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}