{"id":728,"date":"2025-05-29T07:34:15","date_gmt":"2025-05-29T07:34:15","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-chiet-xuat-dong-trung-ha-thao-cordyceps-militaris-extract-hongda\/"},"modified":"2026-09-28T22:28:19","modified_gmt":"2026-09-28T15:28:19","slug":"nguyen-lieu-chiet-xuat-dong-trung-ha-thao-cordyceps-militaris-extract-hongda","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-chiet-xuat-dong-trung-ha-thao-cordyceps-militaris-extract-hongda\/","title":{"rendered":"Chi\u1ebft xu\u1ea5t \u0111\u00f4ng tr\u00f9ng h\u1ea1 th\u1ea3o (Cordyceps militaris): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Chi\u1ebft xu\u1ea5t \u0111\u00f4ng tr\u00f9ng h\u1ea1 th\u1ea3o (Cordyceps militaris): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng<\/h1>\n<p><strong>Chi\u1ebft xu\u1ea5t \u0111\u00f4ng tr\u00f9ng h\u1ea1 th\u1ea3o<\/strong> l\u00e0 cao chi\u1ebft t\u1eeb c\u00e1c lo\u00e0i n\u1ea5m k\u00fd sinh tr\u00ean c\u00f4n tr\u00f9ng thu\u1ed9c nh\u00f3m <em>Cordyceps<\/em>. Tr\u00ean th\u1ecb tr\u01b0\u1eddng c\u00f3 hai ngu\u1ed3n <strong>r\u1ea5t kh\u00e1c nhau<\/strong>: <em>Ophiocordyceps sinensis<\/em> (\u0111\u00f4ng tr\u00f9ng h\u1ea1 th\u1ea3o T\u00e2y T\u1ea1ng, m\u1ecdc t\u1ef1 nhi\u00ean, c\u1ef1c \u0111\u1eaft) v\u00e0 <em>Cordyceps militaris<\/em> (nh\u1ed9ng tr\u00f9ng th\u1ea3o, nu\u00f4i tr\u1ed3ng \u0111\u01b0\u1ee3c, ph\u1ed5 bi\u1ebfn \u1edf Vi\u1ec7t Nam). T\u00ean g\u1ecdi &#8220;\u0111\u00f4ng tr\u00f9ng h\u1ea1 th\u1ea3o&#8221; (m\u00f9a \u0111\u00f4ng l\u00e0 con s\u00e2u, m\u00f9a h\u1ea1 l\u00e0 c\u00e2y c\u1ecf) m\u00f4 t\u1ea3 v\u00f2ng \u0111\u1eddi n\u1ea5m m\u1ecdc l\u00ean t\u1eeb \u1ea5u tr\u00f9ng.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>\u0110\u00f4ng tr\u00f9ng h\u1ea1 th\u1ea3o, tr\u00f9ng th\u1ea3o, cordyceps<\/td>\n<\/tr>\n<tr>\n<td>Lo\u00e0i<\/td>\n<td><em>Cordyceps militaris (L.) Fr.; Ophiocordyceps sinensis (Berk.) G.H.Sung et al. (Cordyceps sinensis)<\/em>, h\u1ecd Cordycipitaceae \/ Ophiocordycipitaceae<\/td>\n<\/tr>\n<tr>\n<td>B\u1ed9 ph\u1eadn d\u00f9ng<\/td>\n<td>Qu\u1ea3 th\u1ec3; s\u1ee3i n\u1ea5m nu\u00f4i c\u1ea5y<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ho\u1ea1t ch\u1ea5t ch\u00ednh<\/td>\n<td>Nucleosid (cordycepin \u2013 3&#8242;-deoxyadenosin, adenosin), polysaccharid, mannitol (acid cordycepic), ergosterol<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u00e2y v\u00e0 d\u01b0\u1ee3c li\u1ec7u<\/h2>\n<p><em>O. sinensis<\/em> k\u00fd sinh tr\u00ean \u1ea5u tr\u00f9ng b\u01b0\u1edbm \u1edf \u0111\u1ed3ng c\u1ecf cao nguy\u00ean T\u00e2y T\u1ea1ng, Himalaya (tr\u00ean 3.500 m); kh\u00f4ng nu\u00f4i tr\u1ed3ng qu\u1ea3 th\u1ec3 \u0111\u01b0\u1ee3c \u1edf quy m\u00f4 th\u01b0\u01a1ng m\u1ea1i, n\u00ean ngu\u1ed3n th\u01b0\u01a1ng m\u1ea1i r\u1ebb h\u01a1n th\u01b0\u1eddng l\u00e0 <strong>s\u1ee3i n\u1ea5m l\u00ean men<\/strong> (v\u00ed d\u1ee5 ch\u1ee7ng Cs-4, <em>Paecilomyces hepiali<\/em>). <em>C. militaris<\/em> c\u00f3 qu\u1ea3 th\u1ec3 m\u00e0u cam, \u0111\u01b0\u1ee3c nu\u00f4i tr\u00ean m\u00f4i tr\u01b0\u1eddng g\u1ea1o, nh\u1ed9ng t\u1eb1m, v\u00e0 l\u00e0 ngu\u1ed3n gi\u00e0u <strong>cordycepin<\/strong>.<\/p>\n<h2>Th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc<\/h2>\n<ul>\n<li><strong>Cordycepin<\/strong> (3&#8242;-deoxyadenosin): nhi\u1ec1u \u1edf <em>C. militaris<\/em>, r\u1ea5t \u00edt \u1edf <em>O. sinensis<\/em> \u2013 l\u00e0 ch\u1ec9 ti\u00eau ph\u00e2n bi\u1ec7t hai lo\u00e0i.<\/li>\n<li><strong><a href=\"https:\/\/cpc1.vn\/en\/nguyen-lieu-adenosine\/\">Adenosin<\/a><\/strong>, c\u00e1c nucleosid kh\u00e1c.<\/li>\n<li>Polysaccharid, D-mannitol (acid cordycepic), ergosterol.<\/li>\n<\/ul>\n<h2>Chi\u1ebft xu\u1ea5t v\u00e0 ti\u00eau chu\u1ea9n h\u00f3a<\/h2>\n<p>Qu\u1ea3 th\u1ec3 ho\u1eb7c s\u1ee3i n\u1ea5m \u0111\u01b0\u1ee3c chi\u1ebft b\u1eb1ng n\u01b0\u1edbc n\u00f3ng ho\u1eb7c ethanol \u2013 n\u01b0\u1edbc, c\u00f4 \u0111\u1eb7c v\u00e0 s\u1ea5y; nguy\u00ean li\u1ec7u ghi h\u00e0m l\u01b0\u1ee3ng cordycepin, adenosin, polysaccharid, v\u00e0 <strong>lo\u00e0i, ngu\u1ed3n<\/strong> (qu\u1ea3 th\u1ec3 t\u1ef1 nhi\u00ean, qu\u1ea3 th\u1ec3 nu\u00f4i tr\u1ed3ng, hay s\u1ee3i n\u1ea5m l\u00ean men).<\/p>\n<h2>Ch\u1ec9 ti\u00eau ch\u1ea5t l\u01b0\u1ee3ng n\u00ean xem<\/h2>\n<ul>\n<li>Cordycepin, adenosin (HPLC); \u0111\u1ecbnh danh lo\u00e0i (gi\u1ea3i tr\u00ecnh t\u1ef1 gen v\u1edbi nguy\u00ean li\u1ec7u \u0111\u1eaft ti\u1ec1n).<\/li>\n<li><strong>Arsen, ch\u00ec<\/strong>: \u0111\u00e3 c\u00f3 c\u1ea3nh b\u00e1o v\u1ec1 \u0111\u00f4ng tr\u00f9ng h\u1ea1 th\u1ea3o t\u1ef1 nhi\u00ean ch\u1ee9a arsen cao; h\u00e0ng gi\u1ea3 (g\u1eafn que, nh\u1ed3i ch\u00ec, nhu\u1ed9m) v\u1edbi nguy\u00ean li\u1ec7u nguy\u00ean con.<\/li>\n<li>Kim lo\u1ea1i n\u1eb7ng, vi sinh v\u1eadt, d\u01b0 l\u01b0\u1ee3ng thu\u1ed1c b\u1ea3o v\u1ec7 th\u1ef1c v\u1eadt; \u0111\u1ed9c t\u1ed1 vi n\u1ea5m v\u1edbi d\u01b0\u1ee3c li\u1ec7u d\u1ec5 m\u1ed1c.<\/li>\n<\/ul>\n<h2>Applications<\/h2>\n<ul>\n<li>Th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe, \u0111\u1ed3 u\u1ed1ng, tr\u00e0; m\u00f3n \u0103n (nh\u1ed9ng tr\u00f9ng th\u1ea3o).<\/li>\n<li>C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n<h2>An to\u00e0n v\u00e0 l\u01b0u \u00fd<\/h2>\n<ul>\n<li>C\u00f3 th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng, thu\u1ed1c \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch.<\/li>\n<li>Ch\u01b0a c\u00f3 \u0111\u1ee7 d\u1eef li\u1ec7u an to\u00e0n cho ph\u1ee5 n\u1eef mang thai, cho con b\u00fa v\u00e0 tr\u1ebb em; ng\u01b0\u1eddi \u0111ang d\u00f9ng thu\u1ed1c n\u00ean h\u1ecfi \u00fd ki\u1ebfn chuy\u00ean gia y t\u1ebf.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Khi d\u00f9ng l\u00e0m th\u00e0nh ph\u1ea7n c\u1ee7a th\u1ef1c ph\u1ea9m ho\u1eb7c th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe, s\u1ea3n ph\u1ea9m tu\u00e2n theo Lu\u1eadt An to\u00e0n th\u1ef1c ph\u1ea9m, Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP v\u00e0 c\u00e1c v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n m\u1edbi nh\u1ea5t tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Cordyceps militaris \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Cordyceps_militaris\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Cordyceps_militaris<\/a><\/li>\n<li>Wikipedia \u2013 Ophiocordyceps sinensis \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Ophiocordyceps_sinensis\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Ophiocordyceps_sinensis<\/a><\/li>\n<li>Wikipedia \u2013 Cordycepin \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Cordycepin\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Cordycepin<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Chi\u1ebft xu\u1ea5t \u0111\u00f4ng tr\u00f9ng h\u1ea1 th\u1ea3o (Cordyceps militaris): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t \u0111\u00f4ng tr\u00f9ng h\u1ea1 th\u1ea3o l\u00e0 cao chi\u1ebft t\u1eeb c\u00e1c lo\u00e0i n\u1ea5m k\u00fd sinh tr\u00ean c\u00f4n tr\u00f9ng thu\u1ed9c nh\u00f3m Cordyceps. Tr\u00ean th\u1ecb tr\u01b0\u1eddng c\u00f3 hai ngu\u1ed3n r\u1ea5t kh\u00e1c nhau: Ophiocordyceps sinensis (\u0111\u00f4ng tr\u00f9ng h\u1ea1 th\u1ea3o T\u00e2y T\u1ea1ng, m\u1ecdc t\u1ef1 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3449,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-728","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-dong-trung-ha-thao.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-dong-trung-ha-thao-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-dong-trung-ha-thao-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-dong-trung-ha-thao-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-dong-trung-ha-thao-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-dong-trung-ha-thao.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-dong-trung-ha-thao.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/chiet-xuat-dong-trung-ha-thao-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":1,"uagb_excerpt":"Chi\u1ebft xu\u1ea5t \u0111\u00f4ng tr\u00f9ng h\u1ea1 th\u1ea3o (Cordyceps militaris): th\u00e0nh ph\u1ea7n, chi\u1ebft xu\u1ea5t v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng Chi\u1ebft xu\u1ea5t \u0111\u00f4ng tr\u00f9ng h\u1ea1 th\u1ea3o l\u00e0 cao chi\u1ebft t\u1eeb c\u00e1c lo\u00e0i n\u1ea5m k\u00fd sinh tr\u00ean c\u00f4n tr\u00f9ng thu\u1ed9c nh\u00f3m Cordyceps. Tr\u00ean th\u1ecb tr\u01b0\u1eddng c\u00f3 hai ngu\u1ed3n r\u1ea5t kh\u00e1c nhau: Ophiocordyceps sinensis (\u0111\u00f4ng tr\u00f9ng h\u1ea1 th\u1ea3o T\u00e2y T\u1ea1ng, m\u1ecdc t\u1ef1&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/728","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=728"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/728\/revisions"}],"predecessor-version":[{"id":3479,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/728\/revisions\/3479"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3449"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=728"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=728"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=728"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}