{"id":727,"date":"2025-05-29T07:33:54","date_gmt":"2025-05-29T07:33:54","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-coenzyme-q10-usp\/"},"modified":"2026-09-28T20:49:19","modified_gmt":"2026-09-28T13:49:19","slug":"nguyen-lieu-coenzyme-q10-usp","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-coenzyme-q10-usp\/","title":{"rendered":"Coenzyme Q10 (ubiquinon): c\u1ea5u t\u1ea1o, d\u1ea1ng oxy h\u00f3a v\u00e0 d\u1ea1ng kh\u1eed, s\u1ea3n xu\u1ea5t"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Coenzyme Q10 (ubiquinon): c\u1ea5u t\u1ea1o, d\u1ea1ng oxy h\u00f3a v\u00e0 d\u1ea1ng kh\u1eed, s\u1ea3n xu\u1ea5t<\/h1>\n<p><strong>Coenzyme Q10<\/strong> (CoQ10, <strong>ubiquinon<\/strong>) l\u00e0 m\u1ed9t quinon tan trong d\u1ea7u c\u00f3 m\u1eb7t trong m\u00e0ng t\u1ebf b\u00e0o c\u1ee7a h\u1ea7u h\u1ebft sinh v\u1eadt; t\u00ean &#8220;ubiquinon&#8221; g\u1ee3i \u00fd t\u00ednh ph\u1ed5 bi\u1ebfn (<em>ubiquitous<\/em>). Trong ty th\u1ec3, CoQ10 l\u00e0 m\u1eaft x\u00edch v\u1eadn chuy\u1ec3n \u0111i\u1ec7n t\u1eed c\u1ee7a chu\u1ed7i h\u00f4 h\u1ea5p t\u1ebf b\u00e0o t\u1ea1o ATP. C\u01a1 th\u1ec3 ng\u01b0\u1eddi t\u1ef1 t\u1ed5ng h\u1ee3p \u0111\u01b0\u1ee3c CoQ10, v\u00e0 nh\u1eadn th\u00eam m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf t\u1eeb th\u1ecbt, c\u00e1.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Coenzyme Q10, CoQ10, ubiquinon-10, ubidecarenon<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c, kh\u1ed1i l\u01b0\u1ee3ng mol<\/td>\n<td>C<sub>59<\/sub>H<sub>90<\/sub>O<sub>4<\/sub> \u2013 863,36 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>303-98-0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u1ea5u t\u1ea1o v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>Nh\u00e2n <strong>benzoquinon<\/strong> g\u1eafn chu\u1ed7i b\u00ean g\u1ed3m <strong>10 \u0111\u01a1n v\u1ecb isopren<\/strong> (n\u00ean c\u00f3 t\u00ean &#8220;Q10&#8221;). Chu\u1ed7i d\u00e0i l\u00e0m CoQ10 r\u1ea5t k\u1ef5 n\u01b0\u1edbc.<\/li>\n<li>T\u1ed3n t\u1ea1i hai d\u1ea1ng chuy\u1ec3n qua l\u1ea1i: <strong>ubiquinon<\/strong> (d\u1ea1ng oxy h\u00f3a, m\u00e0u v\u00e0ng cam) v\u00e0 <strong>ubiquinol<\/strong> (d\u1ea1ng kh\u1eed, m\u00e0u tr\u1eafng ng\u00e0). Ubiquinol d\u1ec5 b\u1ecb oxy h\u00f3a tr\u1edf l\u1ea1i khi ti\u1ebfp x\u00fac kh\u00f4ng kh\u00ed, n\u00ean c\u1ea7n c\u00f4ng ngh\u1ec7 \u1ed5n \u0111\u1ecbnh ri\u00eang.<\/li>\n<li>B\u1ed9t k\u1ebft tinh m\u00e0u v\u00e0ng \u0111\u1ebfn cam, <strong>kh\u00f4ng tan trong n\u01b0\u1edbc<\/strong>, tan trong d\u1ea7u v\u00e0 dung m\u00f4i h\u1eefu c\u01a1; n\u00f3ng ch\u1ea3y \u1edf kho\u1ea3ng 48\u201352 \u00b0C.<\/li>\n<li>Nh\u1ea1y v\u1edbi \u00e1nh s\u00e1ng. \u0110\u1ed3ng ph\u00e2n c\u00f3 ho\u1ea1t t\u00ednh l\u00e0 d\u1ea1ng <strong>all-trans<\/strong>; \u0111\u1ed3ng ph\u00e2n cis l\u00e0 t\u1ea1p ch\u1ea5t c\u1ea7n ki\u1ec3m so\u00e1t.<\/li>\n<\/ul>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>CoQ10 th\u01b0\u01a1ng m\u1ea1i \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t ch\u1ee7 y\u1ebfu b\u1eb1ng <strong>l\u00ean men<\/strong> vi sinh v\u1eadt (n\u1ea5m men ho\u1eb7c vi khu\u1ea9n), r\u1ed3i chi\u1ebft b\u1eb1ng dung m\u00f4i v\u00e0 k\u1ebft tinh; c\u0169ng c\u00f3 ph\u01b0\u01a1ng ph\u00e1p t\u1ed5ng h\u1ee3p ho\u1eb7c b\u00e1n t\u1ed5ng h\u1ee3p. D\u1ea1ng l\u00ean men cho all-trans t\u1ef1 nhi\u00ean.<\/p>\n<h2>D\u1ea1ng b\u00e0o ch\u1ebf<\/h2>\n<p>Do kh\u00f4ng tan trong n\u01b0\u1edbc v\u00e0 c\u00f3 \u0111i\u1ec3m n\u00f3ng ch\u1ea3y th\u1ea5p, CoQ10 th\u01b0\u1eddng \u0111\u01b0\u1ee3c \u0111\u01b0a v\u00e0o <strong>vi\u00ean nang m\u1ec1m<\/strong> (h\u00f2a trong d\u1ea7u), ho\u1eb7c d\u00f9ng d\u1ea1ng b\u1ed9t tan trong n\u01b0\u1edbc (bao vi nang, ph\u1ee9c v\u1edbi cyclodextrin, nh\u0169 t\u01b0\u01a1ng) cho vi\u00ean n\u00e9n v\u00e0 \u0111\u1ed3 u\u1ed1ng.<\/p>\n<h2>Applications<\/h2>\n<ul>\n<li>Th\u1ef1c ph\u1ea9m b\u1ed5 sung; m\u1ef9 ph\u1ea9m (ch\u1ea5t ch\u1ed1ng oxy h\u00f3a).<\/li>\n<li>T\u1ea1i Nh\u1eadt B\u1ea3n, CoQ10 t\u1eebng l\u00e0 thu\u1ed1c tr\u01b0\u1edbc khi \u0111\u01b0\u1ee3c ph\u00e9p d\u00f9ng l\u00e0m th\u1ef1c ph\u1ea9m (n\u0103m 2001).<\/li>\n<\/ul>\n<p>C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/p>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Khi d\u00f9ng l\u00e0m th\u00e0nh ph\u1ea7n c\u1ee7a th\u1ef1c ph\u1ea9m ho\u1eb7c th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe, s\u1ea3n ph\u1ea9m tu\u00e2n theo Lu\u1eadt An to\u00e0n th\u1ef1c ph\u1ea9m, Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP v\u00e0 c\u00e1c v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n m\u1edbi nh\u1ea5t tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Coenzyme Q10 \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Coenzyme_Q10\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Coenzyme_Q10<\/a><\/li>\n<li>Wikidata \u2013 \u0111\u1ecbnh danh h\u00f3a h\u1ecdc (CAS, c\u00f4ng th\u1ee9c, m\u00e3 E) \u2014 <a href=\"https:\/\/www.wikidata.org\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.wikidata.org\/<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Coenzyme Q10 (ubiquinon): c\u1ea5u t\u1ea1o, d\u1ea1ng oxy h\u00f3a v\u00e0 d\u1ea1ng kh\u1eed, s\u1ea3n xu\u1ea5t Coenzyme Q10 (CoQ10, ubiquinon) l\u00e0 m\u1ed9t quinon tan trong d\u1ea7u c\u00f3 m\u1eb7t trong m\u00e0ng t\u1ebf b\u00e0o c\u1ee7a h\u1ea7u h\u1ebft sinh v\u1eadt; t\u00ean &#8220;ubiquinon&#8221; g\u1ee3i \u00fd t\u00ednh ph\u1ed5 bi\u1ebfn (ubiquitous). Trong ty th\u1ec3, CoQ10 l\u00e0 m\u1eaft x\u00edch v\u1eadn chuy\u1ec3n \u0111i\u1ec7n t\u1eed c\u1ee7a chu\u1ed7i [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2900,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-727","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/coenzyme-q10.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/coenzyme-q10-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/coenzyme-q10-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/coenzyme-q10-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/coenzyme-q10-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/coenzyme-q10.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/coenzyme-q10.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/coenzyme-q10-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Coenzyme Q10 (ubiquinon): c\u1ea5u t\u1ea1o, d\u1ea1ng oxy h\u00f3a v\u00e0 d\u1ea1ng kh\u1eed, s\u1ea3n xu\u1ea5t Coenzyme Q10 (CoQ10, ubiquinon) l\u00e0 m\u1ed9t quinon tan trong d\u1ea7u c\u00f3 m\u1eb7t trong m\u00e0ng t\u1ebf b\u00e0o c\u1ee7a h\u1ea7u h\u1ebft sinh v\u1eadt; t\u00ean &#8220;ubiquinon&#8221; g\u1ee3i \u00fd t\u00ednh ph\u1ed5 bi\u1ebfn (ubiquitous). Trong ty th\u1ec3, CoQ10 l\u00e0 m\u1eaft x\u00edch v\u1eadn chuy\u1ec3n \u0111i\u1ec7n t\u1eed c\u1ee7a chu\u1ed7i&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/727","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=727"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/727\/revisions"}],"predecessor-version":[{"id":3033,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/727\/revisions\/3033"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2900"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=727"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=727"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=727"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}