{"id":698,"date":"2025-05-29T07:19:25","date_gmt":"2025-05-29T07:19:25","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-rutin-hoa-hoe\/"},"modified":"2026-09-28T20:57:52","modified_gmt":"2026-09-28T13:57:52","slug":"nguyen-lieu-rutin-hoa-hoe","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-rutin-hoa-hoe\/","title":{"rendered":"Rutin: flavonoid t\u1eeb n\u1ee5 hoa h\u00f2e \u2013 c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, s\u1ea3n xu\u1ea5t"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Rutin: flavonoid t\u1eeb n\u1ee5 hoa h\u00f2e \u2013 c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, s\u1ea3n xu\u1ea5t<\/h1>\n<p><strong>Rutin<\/strong> (rutosid) l\u00e0 m\u1ed9t <strong>flavonoid glycosid<\/strong>: ph\u00e2n t\u1eed flavonol <strong>quercetin<\/strong> g\u1eafn v\u1edbi disaccharid rutinose (rhamnose + glucose). T\u00ean g\u1ecdi xu\u1ea5t ph\u00e1t t\u1eeb c\u00e2y c\u1eedu l\u00fd h\u01b0\u01a1ng (<em>Ruta graveolens<\/em>), n\u01a1i ch\u1ea5t \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n l\u1ea7n \u0111\u1ea7u. \u1ede Vi\u1ec7t Nam, ngu\u1ed3n rutin quen thu\u1ed9c nh\u1ea5t l\u00e0 <strong>n\u1ee5 hoa h\u00f2e<\/strong> (<em>Styphnolobium japonicum<\/em>, t\u00ean c\u0169 <em>Sophora japonica<\/em>).<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Rutin, rutosid, quercetin-3-O-rutinosid, vitamin P (t\u00ean c\u0169)<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c, kh\u1ed1i l\u01b0\u1ee3ng mol<\/td>\n<td>C<sub>27<\/sub>H<sub>30<\/sub>O<sub>16<\/sub> \u2013 610,52 g\/mol (khan); th\u01b0\u01a1ng m\u1ea1i th\u01b0\u1eddng l\u00e0 trihydrat<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>153-18-4<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u1ea5u t\u1ea1o v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>Ph\u1ea7n aglycon quercetin c\u00f3 nhi\u1ec1u nh\u00f3m phenol (hai nh\u00f3m \u2013OH k\u1ec1 nhau tr\u00ean v\u00f2ng B), l\u00e0 c\u01a1 s\u1edf cho kh\u1ea3 n\u0103ng b\u1eaft g\u1ed1c t\u1ef1 do v\u00e0 t\u1ea1o ph\u1ee9c v\u1edbi ion kim lo\u1ea1i.<\/li>\n<li>B\u1ed9t k\u1ebft tinh m\u00e0u <strong>v\u00e0ng \u0111\u1ebfn v\u00e0ng l\u1ee5c<\/strong>, kh\u00f4ng m\u00f9i. <strong>R\u1ea5t \u00edt tan trong n\u01b0\u1edbc l\u1ea1nh<\/strong>, tan h\u01a1n trong n\u01b0\u1edbc n\u00f3ng, ethanol n\u00f3ng v\u00e0 dung d\u1ecbch ki\u1ec1m lo\u00e3ng.<\/li>\n<li>Trong dung d\u1ecbch ki\u1ec1m, rutin d\u1ec5 b\u1ecb oxy h\u00f3a v\u00e0 s\u1eabm m\u00e0u; c\u0169ng \u0111\u1ed5i m\u00e0u khi g\u1eb7p ion s\u1eaft.<\/li>\n<li>&#8220;Vitamin P&#8221; l\u00e0 t\u00ean c\u0169 \u0111\u01b0\u1ee3c \u0111\u1eb7t cho nh\u00f3m flavonoid; ng\u00e0y nay flavonoid kh\u00f4ng \u0111\u01b0\u1ee3c x\u1ebfp l\u00e0 vitamin.<\/li>\n<\/ul>\n<h2>Ngu\u1ed3n g\u1ed1c v\u00e0 s\u1ea3n xu\u1ea5t<\/h2>\n<p>N\u1ee5 hoa h\u00f2e l\u00e0 m\u1ed9t trong nh\u1eefng ngu\u1ed3n gi\u00e0u rutin nh\u1ea5t trong t\u1ef1 nhi\u00ean; rutin c\u0169ng c\u00f3 nhi\u1ec1u trong <strong>ki\u1ec1u m\u1ea1ch<\/strong> v\u00e0 qu\u1ea3 c\u1ee7a c\u00e2y <em>Dimorphandra<\/em> (Brazil). Rutin th\u01b0\u01a1ng m\u1ea1i \u0111\u01b0\u1ee3c <strong>chi\u1ebft<\/strong> t\u1eeb c\u00e1c ngu\u1ed3n n\u00e0y b\u1eb1ng n\u01b0\u1edbc n\u00f3ng ho\u1eb7c c\u1ed3n, sau \u0111\u00f3 t\u1eadn d\u1ee5ng \u0111\u1ed9 tan th\u1ea5p khi ngu\u1ed9i \u0111\u1ec3 k\u1ebft tinh v\u00e0 tinh ch\u1ebf. Rutin c\u0169ng l\u00e0 nguy\u00ean li\u1ec7u \u0111\u1ec3 b\u00e1n t\u1ed5ng h\u1ee3p quercetin (th\u1ee7y ph\u00e2n) v\u00e0 c\u00e1c d\u1eabn ch\u1ea5t nh\u01b0 troxerutin.<\/p>\n<h2>Applications<\/h2>\n<ul>\n<li>Th\u1ef1c ph\u1ea9m b\u1ed5 sung; nguy\u00ean li\u1ec7u d\u01b0\u1ee3c ph\u1ea9m (c\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft).<\/li>\n<li>Ch\u1ea5t t\u1ea1o m\u00e0u v\u00e0ng, ch\u1ea5t ch\u1ed1ng oxy h\u00f3a trong m\u1ed9t s\u1ed1 \u1ee9ng d\u1ee5ng th\u1ef1c ph\u1ea9m v\u00e0 m\u1ef9 ph\u1ea9m theo quy \u0111\u1ecbnh.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Khi d\u00f9ng l\u00e0m th\u00e0nh ph\u1ea7n c\u1ee7a th\u1ef1c ph\u1ea9m ho\u1eb7c th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe, s\u1ea3n ph\u1ea9m tu\u00e2n theo Lu\u1eadt An to\u00e0n th\u1ef1c ph\u1ea9m, Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP v\u00e0 c\u00e1c v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n m\u1edbi nh\u1ea5t tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Rutin \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Rutin\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Rutin<\/a><\/li>\n<li>Wikidata \u2013 \u0111\u1ecbnh danh h\u00f3a h\u1ecdc (CAS, c\u00f4ng th\u1ee9c) \u2014 <a href=\"https:\/\/www.wikidata.org\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.wikidata.org\/<\/a><\/li>\n<li>Wikipedia \u2013 Styphnolobium japonicum (hoa h\u00f2e) \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Styphnolobium_japonicum\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Styphnolobium_japonicum<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Rutin: flavonoid t\u1eeb n\u1ee5 hoa h\u00f2e \u2013 c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, s\u1ea3n xu\u1ea5t Rutin (rutosid) l\u00e0 m\u1ed9t flavonoid glycosid: ph\u00e2n t\u1eed flavonol quercetin g\u1eafn v\u1edbi disaccharid rutinose (rhamnose + glucose). T\u00ean g\u1ecdi xu\u1ea5t ph\u00e1t t\u1eeb c\u00e2y c\u1eedu l\u00fd h\u01b0\u01a1ng (Ruta graveolens), n\u01a1i ch\u1ea5t \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n l\u1ea7n \u0111\u1ea7u. \u1ede Vi\u1ec7t Nam, ngu\u1ed3n rutin quen thu\u1ed9c [&hellip;]<\/p>","protected":false},"author":1,"featured_media":2951,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-698","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/rutin.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/rutin-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/rutin-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/rutin-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/rutin-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/rutin.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/rutin.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/rutin-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Rutin: flavonoid t\u1eeb n\u1ee5 hoa h\u00f2e \u2013 c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t, s\u1ea3n xu\u1ea5t Rutin (rutosid) l\u00e0 m\u1ed9t flavonoid glycosid: ph\u00e2n t\u1eed flavonol quercetin g\u1eafn v\u1edbi disaccharid rutinose (rhamnose + glucose). T\u00ean g\u1ecdi xu\u1ea5t ph\u00e1t t\u1eeb c\u00e2y c\u1eedu l\u00fd h\u01b0\u01a1ng (Ruta graveolens), n\u01a1i ch\u1ea5t \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n l\u1ea7n \u0111\u1ea7u. \u1ede Vi\u1ec7t Nam, ngu\u1ed3n rutin quen thu\u1ed9c&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/698","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=698"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/698\/revisions"}],"predecessor-version":[{"id":3084,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/698\/revisions\/3084"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2951"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=698"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=698"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=698"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}