{"id":4349,"date":"2026-09-29T21:56:51","date_gmt":"2026-09-29T14:56:51","guid":{"rendered":"https:\/\/cpc1.vn\/ngoc-vo-phan\/"},"modified":"2026-09-30T15:15:29","modified_gmt":"2026-09-30T08:15:29","slug":"ngoc-vo-phan","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/ngoc-vo-phan\/","title":{"rendered":"Lithospermum officinale (gromwell): \u0111\u1eb7c \u0111i\u1ec3m, th\u00e0nh ph\u1ea7n v\u00e0 \u1ee9ng d\u1ee5ng trong m\u1ef9 ph\u1ea9m"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Lithospermum officinale (gromwell): \u0111\u1eb7c \u0111i\u1ec3m, th\u00e0nh ph\u1ea7n v\u00e0 \u1ee9ng d\u1ee5ng trong m\u1ef9 ph\u1ea9m<\/h1>\n<p><strong>Lithospermum officinale<\/strong> (<em>common gromwell<\/em>) l\u00e0 c\u00e2y th\u1ea3o h\u1ecd V\u00f2i voi ch\u00e2u \u00c2u c\u00f3 h\u1ea1t tr\u1eafng b\u00f3ng c\u1ee9ng nh\u01b0 s\u1ee9. Trong m\u1ef9 ph\u1ea9m, chi\u1ebft xu\u1ea5t r\u1ec5 c\u00f3 t\u00ean INCI <em>Lithospermum Officinale Root Extract<\/em>. Tr\u00ean th\u1ecb tr\u01b0\u1eddng \u0110\u00f4ng \u00c1, nhi\u1ec1u nguy\u00ean li\u1ec7u \u201cgromwell\u201d th\u1ef1c ch\u1ea5t l\u1ea5y t\u1eeb lo\u00e0i g\u1ea7n l\u00e0 t\u1eed th\u1ea3o (<em>Lithospermum erythrorhizon<\/em>) \u2014 c\u1ea7n x\u00e1c nh\u1eadn \u0111\u00fang lo\u00e0i v\u1edbi nh\u00e0 s\u1ea3n xu\u1ea5t.<\/p>\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/ngoc-vo-phan-cay.jpg\" alt=\"C\u00e2y ng\u1ecdc v\u1ecf ph\u1ea5n (t\u1eed th\u1ea3o ch\u00e2u \u00c2u) (Lithospermum officinale)\"\/><figcaption>Ng\u1ecdc v\u1ecf ph\u1ea5n (t\u1eed th\u1ea3o ch\u00e2u \u00c2u) (<em>Lithospermum officinale<\/em>). \u1ea2nh: Robert Flogaus-Faust, <a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Lithospermum_officinale_RF.jpg\" rel=\"nofollow noopener\" target=\"_blank\">Wikimedia Commons<\/a>, gi\u1ea5y ph\u00e9p <a href=\"https:\/\/creativecommons.org\/licenses\/by\/4.0\" rel=\"nofollow noopener\" target=\"_blank\">CC BY 4.0<\/a>.<\/figcaption><\/figure>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Common gromwell (ch\u00e2u \u00c2u); c\u00f9ng chi v\u1edbi t\u1eed th\u1ea3o (<em>Lithospermum erythrorhizon<\/em>)<\/td>\n<\/tr>\n<tr>\n<td>T\u00ean khoa h\u1ecdc<\/td>\n<td><em>Lithospermum officinale<\/em> L.<\/td>\n<\/tr>\n<tr>\n<td>H\u1ecd<\/td>\n<td>V\u00f2i voi (Boraginaceae)<\/td>\n<\/tr>\n<tr>\n<td>B\u1ed9 ph\u1eadn d\u00f9ng<\/td>\n<td>R\u1ec5<\/td>\n<\/tr>\n<tr>\n<td>T\u00ean INCI<\/td>\n<td>Lithospermum Officinale Root Extract<\/td>\n<\/tr>\n<tr>\n<td>Ch\u1ee9c n\u0103ng (CosIng)<\/td>\n<td>d\u01b0\u1ee1ng da<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ho\u1ea1t ch\u1ea5t ch\u00ednh<\/td>\n<td>Naphthoquinon (d\u1eabn ch\u1ea5t shikonin, ch\u1ee7 y\u1ebfu \u1edf lo\u00e0i t\u1eed th\u1ea3o \u0111\u1ecf), acid phenolic (acid rosmarinic, acid lithospermic), alcaloid pyrrolizidin (l\u01b0\u1ee3ng nh\u1ecf)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>\u0110\u1eb7c \u0111i\u1ec3m c\u1ee7a c\u00e2y<\/h2>\n<p><em>Lithospermum officinale<\/em> l\u00e0 c\u00e2y th\u1ea3o s\u1ed1ng l\u00e2u n\u0103m cao 30\u201380 cm, th\u00e2n ph\u00e2n nh\u00e1nh, ph\u1ee7 l\u00f4ng r\u00e1p. L\u00e1 h\u00ecnh m\u00e1c, kh\u00f4ng cu\u1ed1ng, g\u00e2n b\u00ean n\u1ed5i r\u00f5. Hoa nh\u1ecf m\u00e0u tr\u1eafng kem \u0111\u1ebfn v\u00e0ng l\u1ee5c, h\u00ecnh ph\u1ec5u, m\u1ecdc \u1edf n\u00e1ch l\u00e1. Qu\u1ea3 g\u1ed3m 1\u20134 h\u1ea1ch nh\u1ecf m\u00e0u tr\u1eafng ng\u00e0, b\u00f3ng v\u00e0 r\u1ea5t c\u1ee9ng \u2014 ngu\u1ed3n g\u1ed1c t\u00ean chi (<em>lithos<\/em> = \u0111\u00e1, <em>sperma<\/em> = h\u1ea1t). Lo\u00e0i m\u1ecdc \u1edf b\u00eca r\u1eebng, b\u1ee5i c\u00e2y kh\u1eafp ch\u00e2u \u00c2u, T\u00e2y \u00c1. T\u1eed th\u1ea3o (<em>L. erythrorhizon<\/em>) v\u00f9ng \u0110\u00f4ng \u00c1 c\u00f3 r\u1ec5 \u0111\u1ecf t\u00edm gi\u00e0u shikonin, l\u00e0 v\u1ecb thu\u1ed1c v\u00e0 ngu\u1ed3n ch\u1ea5t m\u00e0u t\u00edm truy\u1ec1n th\u1ed1ng.<\/p>\n<h2>Th\u00e0nh ph\u1ea7n h\u00f3a h\u1ecdc<\/h2>\n<ul>\n<li><strong>Naphthoquinon<\/strong>: shikonin v\u00e0 d\u1eabn ch\u1ea5t \u2014 s\u1eafc t\u1ed1 \u0111\u1ecf t\u00edm t\u1eadp trung \u1edf v\u1ecf r\u1ec5 t\u1eed th\u1ea3o (<em>L. erythrorhizon<\/em>); r\u1ec5 <em>L. officinale<\/em> c\u00f3 h\u00e0m l\u01b0\u1ee3ng th\u1ea5p h\u01a1n nhi\u1ec1u.<\/li>\n<li><strong>Acid phenolic<\/strong>: acid rosmarinic, acid lithospermic.<\/li>\n<li><strong>Alcaloid pyrrolizidin<\/strong> \u2014 nh\u00f3m ch\u1ea5t th\u01b0\u1eddng g\u1eb7p trong h\u1ecd V\u00f2i voi.<\/li>\n<\/ul>\n<h2>D\u1ea1ng nguy\u00ean li\u1ec7u trong m\u1ef9 ph\u1ea9m<\/h2>\n<ul>\n<li><strong>Lithospermum Officinale Root Extract<\/strong>: chi\u1ebft xu\u1ea5t b\u1eb1ng dung m\u00f4i (th\u01b0\u1eddng l\u00e0 n\u01b0\u1edbc, glycol ho\u1eb7c ethanol), sau \u0111\u00f3 pha lo\u00e3ng trong dung m\u00f4i mang. Ch\u1ee9c n\u0103ng theo CosIng: d\u01b0\u1ee1ng da.<\/li>\n<\/ul>\n<h2>Applications in Cosmetics<\/h2>\n<ul>\n<li>D\u00f9ng trong kem d\u01b0\u1ee1ng, toner, son d\u01b0\u1ee1ng v\u1edbi vai tr\u00f2 d\u01b0\u1ee1ng da theo CosIng.<\/li>\n<li>Chi\u1ebft xu\u1ea5t r\u1ec5 t\u1eed th\u1ea3o (gi\u00e0u shikonin) c\u00f2n \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m ch\u1ea5t m\u00e0u t\u00edm \u0111\u1ecf t\u1ef1 nhi\u00ean trong m\u1ed9t s\u1ed1 m\u1ef9 ph\u1ea9m H\u00e0n Qu\u1ed1c, Nh\u1eadt B\u1ea3n.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n<p>Theo c\u01a1 s\u1edf d\u1eef li\u1ec7u CosIng c\u1ee7a \u1ee6y ban ch\u00e2u \u00c2u, c\u00e1c t\u00ean INCI n\u00eau tr\u00ean kh\u00f4ng thu\u1ed9c ph\u1ee5 l\u1ee5c ch\u1ea5t c\u1ea5m (Annex II) hay ch\u1ea5t b\u1ecb h\u1ea1n ch\u1ebf (Annex III) c\u1ee7a Quy \u0111\u1ecbnh (EC) 1223\/2009 t\u1ea1i th\u1eddi \u0111i\u1ec3m vi\u1ebft b\u00e0i. C\u00e1c ph\u1ee5 l\u1ee5c c\u1ee7a Hi\u1ec7p \u0111\u1ecbnh m\u1ef9 ph\u1ea9m ASEAN (ACD) \u0111\u01b0\u1ee3c x\u00e2y d\u1ef1ng v\u00e0 c\u1eadp nh\u1eadt theo danh m\u1ee5c c\u1ee7a EU, doanh nghi\u1ec7p v\u1eabn c\u1ea7n \u0111\u1ed1i chi\u1ebfu ph\u1ee5 l\u1ee5c ACD hi\u1ec7n h\u00e0nh.<\/p>\n<p>T\u1ea1i Vi\u1ec7t Nam, m\u1ef9 ph\u1ea9m \u0111\u01b0\u1ee3c qu\u1ea3n l\u00fd theo Th\u00f4ng t\u01b0 06\/2011\/TT-BYT v\u00e0 c\u00e1c v\u0103n b\u1ea3n s\u1eeda \u0111\u1ed5i, b\u1ed5 sung: s\u1ea3n ph\u1ea9m ph\u1ea3i \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 tr\u01b0\u1edbc khi l\u01b0u h\u00e0nh, t\u1ed5 ch\u1ee9c \u0111\u01b0a s\u1ea3n ph\u1ea9m ra th\u1ecb tr\u01b0\u1eddng ch\u1ecbu tr\u00e1ch nhi\u1ec7m v\u1ec1 an to\u00e0n v\u00e0 l\u01b0u h\u1ed3 s\u01a1 th\u00f4ng tin s\u1ea3n ph\u1ea9m (PIF). T\u00ednh n\u0103ng ghi tr\u00ean nh\u00e3n v\u00e0 trong qu\u1ea3ng c\u00e1o ph\u1ea3i theo H\u01b0\u1edbng d\u1eabn c\u00f4ng b\u1ed1 t\u00ednh n\u0103ng s\u1ea3n ph\u1ea9m m\u1ef9 ph\u1ea9m c\u1ee7a ASEAN \u2014 m\u1ef9 ph\u1ea9m kh\u00f4ng \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 c\u00f4ng d\u1ee5ng nh\u01b0 thu\u1ed1c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Lithospermum officinale \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Lithospermum_officinale\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Lithospermum_officinale<\/a><\/li>\n<li>Wikipedia \u2013 Lithospermum erythrorhizon \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Lithospermum_erythrorhizon\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Lithospermum_erythrorhizon<\/a><\/li>\n<li>Wikipedia \u2013 Shikonin \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Shikonin\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Shikonin<\/a><\/li>\n<li>European Commission \u2013 CosIng: Lithospermum Officinale Root Extract \u2014 <a href=\"https:\/\/ec.europa.eu\/growth\/tools-databases\/cosing\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/ec.europa.eu\/growth\/tools-databases\/cosing\/<\/a><\/li>\n<li>GBIF Backbone Taxonomy \u2013 Lithospermum officinale L. \u2014 <a href=\"https:\/\/www.gbif.org\/species\/2926086\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.gbif.org\/species\/2926086<\/a><\/li>\n<li>\u1ea2nh: Robert Flogaus-Faust, Wikimedia Commons, CC BY 4.0 \u2014 <a href=\"https:\/\/commons.wikimedia.org\/wiki\/File:Lithospermum_officinale_RF.jpg\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/commons.wikimedia.org\/wiki\/File:Lithospermum_officinale_RF.jpg<\/a><\/li>\n<li>ASEAN Cosmetic Directive \u2013 Annexes v\u00e0 ASEAN Guidelines for Cosmetic Claims \u2014 <a href=\"https:\/\/aseancosmetics.org\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/aseancosmetics.org\/<\/a><\/li>\n<li>B\u1ed9 Y t\u1ebf (2011). Th\u00f4ng t\u01b0 06\/2011\/TT-BYT quy \u0111\u1ecbnh v\u1ec1 qu\u1ea3n l\u00fd m\u1ef9 ph\u1ea9m<\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Lithospermum officinale (gromwell): \u0111\u1eb7c \u0111i\u1ec3m, th\u00e0nh ph\u1ea7n v\u00e0 \u1ee9ng d\u1ee5ng trong m\u1ef9 ph\u1ea9m Lithospermum officinale (common gromwell) l\u00e0 c\u00e2y th\u1ea3o h\u1ecd V\u00f2i voi ch\u00e2u \u00c2u c\u00f3 h\u1ea1t tr\u1eafng b\u00f3ng c\u1ee9ng nh\u01b0 s\u1ee9. Trong m\u1ef9 ph\u1ea9m, chi\u1ebft xu\u1ea5t r\u1ec5 c\u00f3 t\u00ean INCI Lithospermum Officinale Root Extract. Tr\u00ean th\u1ecb tr\u01b0\u1eddng \u0110\u00f4ng \u00c1, nhi\u1ec1u nguy\u00ean li\u1ec7u \u201cgromwell\u201d th\u1ef1c [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4348,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-4349","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/ngoc-vo-phan-cay.jpg",938,1200,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/ngoc-vo-phan-cay-150x150.jpg",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/ngoc-vo-phan-cay-235x300.jpg",235,300,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/ngoc-vo-phan-cay-768x983.jpg",768,983,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/ngoc-vo-phan-cay-800x1024.jpg",800,1024,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/ngoc-vo-phan-cay.jpg",938,1200,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/ngoc-vo-phan-cay.jpg",938,1200,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/ngoc-vo-phan-cay-9x12.jpg",9,12,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Lithospermum officinale (gromwell): \u0111\u1eb7c \u0111i\u1ec3m, th\u00e0nh ph\u1ea7n v\u00e0 \u1ee9ng d\u1ee5ng trong m\u1ef9 ph\u1ea9m Lithospermum officinale (common gromwell) l\u00e0 c\u00e2y th\u1ea3o h\u1ecd V\u00f2i voi ch\u00e2u \u00c2u c\u00f3 h\u1ea1t tr\u1eafng b\u00f3ng c\u1ee9ng nh\u01b0 s\u1ee9. Trong m\u1ef9 ph\u1ea9m, chi\u1ebft xu\u1ea5t r\u1ec5 c\u00f3 t\u00ean INCI Lithospermum Officinale Root Extract. Tr\u00ean th\u1ecb tr\u01b0\u1eddng \u0110\u00f4ng \u00c1, nhi\u1ec1u nguy\u00ean li\u1ec7u \u201cgromwell\u201d th\u1ef1c&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/4349","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=4349"}],"version-history":[{"count":3,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/4349\/revisions"}],"predecessor-version":[{"id":4978,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/4349\/revisions\/4978"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/4348"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=4349"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=4349"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=4349"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}