{"id":3664,"date":"2026-09-29T09:32:24","date_gmt":"2026-09-29T02:32:24","guid":{"rendered":"https:\/\/cpc1.vn\/saccarose-octaacetat\/"},"modified":"2026-09-29T09:32:24","modified_gmt":"2026-09-29T02:32:24","slug":"saccarose-octaacetat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/saccarose-octaacetat\/","title":{"rendered":"Saccarose octaacetat \u2013 ch\u1ea5t l\u00e0m bi\u1ebfn t\u00ednh c\u1ed3n, ch\u1ea5t t\u1ea1o v\u1ecb \u0111\u1eafng"},"content":{"rendered":"

Saccarose octaacetat \u2013 ch\u1ea5t l\u00e0m bi\u1ebfn t\u00ednh c\u1ed3n, ch\u1ea5t t\u1ea1o v\u1ecb \u0111\u1eafng<\/h1>\n

Saccarose octaacetat<\/strong> (octaacetylsucrose) l\u00e0 ester octaacetat c\u1ee7a saccarose, d\u1ea1ng b\u1ed9t tr\u1eafng h\u00fat \u1ea9m, g\u1ea7n nh\u01b0 kh\u00f4ng m\u00f9i, v\u1ecb \u0111\u1eafng. Trong b\u00e0o ch\u1ebf, ch\u1ea5t n\u00e0y d\u00f9ng l\u00e0m ch\u1ea5t l\u00e0m bi\u1ebfn t\u00ednh c\u1ed3n<\/strong> v\u00e0 ch\u1ea5t t\u1ea1o v\u1ecb \u0111\u1eafng<\/strong> cho thu\u1ed1c u\u1ed1ng; c\u0169ng d\u00f9ng trong m\u1ef9 ph\u1ea9m v\u00e0 l\u00e0m ch\u1ea5t t\u1ea1o h\u01b0\u01a1ng th\u1ef1c ph\u1ea9m.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nOctaacetylsucrose, sucrose octaacetat<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n126-14-7<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC28<\/sub>H38<\/sub>O19<\/sub> \u2013 678,59<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t l\u00e0m bi\u1ebfn t\u00ednh c\u1ed3n, ch\u1ea5t t\u1ea1o h\u01b0\u01a1ng (v\u1ecb \u0111\u1eafng)<\/td>\n<\/tr>\n
D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nUSP-NF<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • Ch\u1ea5t l\u00e0m bi\u1ebfn t\u00ednh c\u1ed3n v\u00e0 t\u1ea1o v\u1ecb \u0111\u1eafng trong thu\u1ed1c u\u1ed1ng.<\/li>\n
  • Ch\u1ea5t l\u00e0m bi\u1ebfn t\u00ednh trong m\u1ef9 ph\u1ea9m; ch\u1ea5t t\u1ea1o h\u01b0\u01a1ng trong th\u1ef1c ph\u1ea9m.<\/li>\n
  • Ch\u1ec9 0,06% saccarose octaacetat \u0111\u00e3 l\u00e0m \u0111\u01b0\u1eddng qu\u00e1 \u0111\u1eafng \u0111\u1ec3 \u0103n.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • B\u1ed9t tr\u1eafng h\u00fat \u1ea9m, g\u1ea7n nh\u01b0 kh\u00f4ng m\u00f9i, v\u1ecb \u0111\u1eafng.<\/li>\n
    • \u0110i\u1ec3m ch\u1ea3y kho\u1ea3ng 89 \u00b0C (USP-NF: kh\u00f4ng d\u01b0\u1edbi 78 \u00b0C), ph\u00e2n h\u1ee7y tr\u00ean 285 \u00b0C; t\u1ef7 tr\u1ecdng ri\u00eang 1,28; chi\u1ebft su\u1ea5t 1,47; n\u0103ng su\u1ea5t quay c\u1ef1c +58,5\u00b0. USP-NF: h\u00e0m l\u01b0\u1ee3ng 98,0\u2013100,5% (ch\u1ebf ph\u1ea9m khan).<\/li>\n<\/ul>\n\n\n\n\n\n\n\n\n\n\n
      Dung m\u00f4i<\/th>\n\u0110\u1ed9 tan \u1edf 20 \u00b0C<\/th>\n<\/tr>\n<\/thead>\n
      Aceton<\/td>\n1 trong 0,3<\/td>\n<\/tr>\n
      Toluen<\/td>\n1 trong 0,5<\/td>\n<\/tr>\n
      Benzen<\/td>\n1 trong 0,6<\/td>\n<\/tr>\n
      Acid acetic b\u0103ng<\/td>\n1 trong 0,7<\/td>\n<\/tr>\n
      Ethanol 95%<\/td>\n1 trong 11<\/td>\n<\/tr>\n
      N\u01b0\u1edbc<\/td>\n1 trong 1100<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

      R\u1ea5t d\u1ec5 tan trong methanol, cloroform; tan trong ether.<\/p>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ec1n. B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn kh\u00ed, n\u01a1i m\u00e1t (2\u20138 \u00b0C), kh\u00f4 \u2013 h\u01a1i \u1ea9m c\u00f3 th\u1ec3 l\u00e0m k\u00e9m b\u1ec1n.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t oxy h\u00f3a m\u1ea1nh.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Th\u01b0\u1eddng t\u1ed5ng h\u1ee3p h\u00f3a h\u1ecdc, v\u00ed d\u1ee5 acetyl h\u00f3a saccarose c\u00f3 x\u00fac t\u00e1c pyridin. Trong t\u1ef1 nhi\u00ean, r\u1ec5 Clematis japonica<\/em> ch\u1ee9a kho\u1ea3ng 0,15% saccarose octaacetat (kh\u1ed1i l\u01b0\u1ee3ng kh\u00f4).<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
        \n
      • H\u01a1i nguy h\u1ea1i khi ti\u1ebfp x\u00fac da (k\u00edch \u1ee9ng), nu\u1ed1t ho\u1eb7c h\u00edt.<\/li>\n
      • LD50<\/sub> (th\u1ecf, qua da): tr\u00ean 5 g\/kg; (chu\u1ed9t c\u1ed1ng, u\u1ed1ng): tr\u00ean 5 g\/kg.<\/li>\n
      • \u0110un t\u1edbi ph\u00e2n h\u1ee7y sinh kh\u00f3i cay, k\u00edch \u1ee9ng. \u0110eo g\u0103ng ch\u1ed1ng h\u00f3a ch\u1ea5t v\u00e0 k\u00ednh; kh\u00f4ng c\u1ea7n b\u1ea3o v\u1ec7 h\u00f4 h\u1ea5p nh\u01b0ng c\u00f3 th\u1ec3 d\u00f9ng kh\u1ea9u trang ch\u1ed1ng b\u1ee5i.<\/li>\n<\/ul>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • C\u00f3 trong danh m\u1ee5c EAFUS; FDA ch\u1ea5p thu\u1eadn l\u00e0m ph\u1ee5 gia th\u1ef1c ph\u1ea9m tr\u1ef1c ti\u1ebfp v\u00e0 gi\u00e1n ti\u1ebfp; c\u00f3 trong Canadian Natural Health Products Ingredients Database.<\/li>\n
        • T\u1ea1i M\u1ef9, do thi\u1ebfu d\u1eef li\u1ec7u, thu\u1ed1c kh\u00f4ng k\u00ea \u0111\u01a1n d\u00f9ng \u0111\u1ec3 ch\u1ed1ng c\u1eafn m\u00f3ng tay, m\u00fat ng\u00f3n tay (k\u1ec3 c\u1ea3 ch\u1ee9a saccarose octaacetat) kh\u00f4ng \u0111\u01b0\u1ee3c c\u00f4ng nh\u1eadn chung l\u00e0 an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3.<\/li>\n
        • C\u00f3 chuy\u00ean lu\u1eadn trong USP-NF.<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan<\/h2>\n

          Denatonium benzoat, natri acetat, saccarose.<\/p>\n

          Ghi ch\u00fa:<\/strong> s\u1ed1 EINECS 204-772-1; PubChem CID 219904.<\/p>\n

          Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

          N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Sucrose Octaacetate<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

          \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

          L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          Saccarose octaacetat \u2013 ch\u1ea5t l\u00e0m bi\u1ebfn t\u00ednh c\u1ed3n, ch\u1ea5t t\u1ea1o v\u1ecb \u0111\u1eafng Saccarose octaacetat (octaacetylsucrose) l\u00e0 ester octaacetat c\u1ee7a saccarose, d\u1ea1ng b\u1ed9t tr\u1eafng h\u00fat \u1ea9m, g\u1ea7n nh\u01b0 kh\u00f4ng m\u00f9i, v\u1ecb \u0111\u1eafng. Trong b\u00e0o ch\u1ebf, ch\u1ea5t n\u00e0y d\u00f9ng l\u00e0m ch\u1ea5t l\u00e0m bi\u1ebfn t\u00ednh c\u1ed3n v\u00e0 ch\u1ea5t t\u1ea1o v\u1ecb \u0111\u1eafng cho thu\u1ed1c u\u1ed1ng; c\u0169ng d\u00f9ng trong m\u1ef9 […]<\/p>\n","protected":false},"author":1,"featured_media":3663,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3664","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/saccarose-octaacetat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/saccarose-octaacetat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/saccarose-octaacetat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/saccarose-octaacetat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/saccarose-octaacetat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/saccarose-octaacetat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/saccarose-octaacetat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/saccarose-octaacetat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Saccarose octaacetat \u2013 ch\u1ea5t l\u00e0m bi\u1ebfn t\u00ednh c\u1ed3n, ch\u1ea5t t\u1ea1o v\u1ecb \u0111\u1eafng Saccarose octaacetat (octaacetylsucrose) l\u00e0 ester octaacetat c\u1ee7a saccarose, d\u1ea1ng b\u1ed9t tr\u1eafng h\u00fat \u1ea9m, g\u1ea7n nh\u01b0 kh\u00f4ng m\u00f9i, v\u1ecb \u0111\u1eafng. Trong b\u00e0o ch\u1ebf, ch\u1ea5t n\u00e0y d\u00f9ng l\u00e0m ch\u1ea5t l\u00e0m bi\u1ebfn t\u00ednh c\u1ed3n v\u00e0 ch\u1ea5t t\u1ea1o v\u1ecb \u0111\u1eafng cho thu\u1ed1c u\u1ed1ng; c\u0169ng d\u00f9ng trong m\u1ef9…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3664","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3664"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3664\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3663"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3664"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3664"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3664"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}