{"id":3660,"date":"2026-09-29T09:31:01","date_gmt":"2026-09-29T02:31:01","guid":{"rendered":"https:\/\/cpc1.vn\/natri-thiosulfat\/"},"modified":"2026-09-29T09:31:01","modified_gmt":"2026-09-29T02:31:01","slug":"natri-thiosulfat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/natri-thiosulfat\/","title":{"rendered":"Natri thiosulfat \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a cho thu\u1ed1c nh\u1ecf m\u1eaft, ti\u00eam, u\u1ed1ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Natri thiosulfat \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a cho thu\u1ed1c nh\u1ecf m\u1eaft, ti\u00eam, u\u1ed1ng<\/h1>\n<p><strong>Natri thiosulfat<\/strong> (Na<sub>2<\/sub>S<sub>2<\/sub>O<sub>3<\/sub>) th\u01b0\u1eddng \u1edf d\u1ea1ng pentahydrat, tinh th\u1ec3 ho\u1eb7c b\u1ed9t k\u1ebft tinh kh\u00f4ng m\u00e0u, kh\u00f4ng m\u00f9i. Trong b\u00e0o ch\u1ebf, natri thiosulfat l\u00e0 <strong>ch\u1ea5t ch\u1ed1ng oxy h\u00f3a<\/strong> cho thu\u1ed1c nh\u1ecf m\u1eaft, thu\u1ed1c ti\u00eam t\u0129nh m\u1ea1ch v\u00e0 thu\u1ed1c u\u1ed1ng.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean kh\u00e1c<\/td>\n<td>Dinatri thiosulfat, natri hyposulfit, natrii thiosulfas, mu\u1ed1i dinatri c\u1ee7a acid thiosulfuric<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>7772-98-7 (khan); 10102-17-7 (pentahydrat)<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\n<td>Na<sub>2<\/sub>S<sub>2<\/sub>O<sub>3<\/sub> \u2013 158,11 (khan); Na<sub>2<\/sub>S<sub>2<\/sub>O<sub>3<\/sub>\u00b75H<sub>2<\/sub>O \u2013 248,2 (pentahydrat)<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\n<td>Ch\u1ea5t ch\u1ed1ng oxy h\u00f3a<\/td>\n<\/tr>\n<tr>\n<td>D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\n<td>BP (Sodium Thiosulphate), JP (Sodium Thiosulfate Hydrate), Ph.Eur., USP-NF<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Applications<\/h2>\n<ul>\n<li>Ch\u1ea5t ch\u1ed1ng oxy h\u00f3a trong dung d\u1ecbch v\u00e0 h\u1ed7n d\u1ecbch nh\u1ecf m\u1eaft, dung d\u1ecbch ti\u00eam t\u0129nh m\u1ea1ch, nang, dung d\u1ecbch v\u00e0 vi\u00ean u\u1ed1ng.<\/li>\n<li>Thu\u1ed1c th\u1eed trong h\u00f3a ph\u00e2n t\u00edch.<\/li>\n<\/ul>\n<h2>M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>Tinh th\u1ec3, b\u1ed9t k\u1ebft tinh ho\u1eb7c h\u1ea1t kh\u00f4ng m\u00e0u, kh\u00f4ng m\u00f9i; l\u00ean hoa trong kh\u00f4ng kh\u00ed kh\u00f4, ch\u1ea3y r\u1eefa nh\u1eb9 trong kh\u00f4ng kh\u00ed \u1ea9m.<\/li>\n<li>Dung d\u1ecbch n\u01b0\u1edbc (pentahydrat) g\u1ea7n trung t\u00ednh, pH 6,5\u20138,0; t\u1ef7 tr\u1ecdng 1,69 g\/cm\u00b3 (pentahydrat).<\/li>\n<li>Tan trong n\u01b0\u1edbc; h\u1ea7u nh\u01b0 kh\u00f4ng tan trong ethanol 95%.<\/li>\n<li>D\u01b0\u1ee3c \u0111i\u1ec3n: h\u00e0m l\u01b0\u1ee3ng (ch\u1ebf ph\u1ea9m kh\u00f4) 99,0\u2013101,0% (USP-NF: 99,0\u2013100,5%); n\u01b0\u1edbc 32,0\u201337% v\u1edbi d\u1ea1ng pentahydrat.<\/li>\n<\/ul>\n<h2>\u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n<p>Ph\u00e2n h\u1ee7y khi \u0111un n\u00f3ng. B\u1ea3o qu\u1ea3n n\u01a1i m\u00e1t, bao b\u00ec \u0111\u1eady k\u00edn, kh\u00f4, th\u00f4ng tho\u00e1ng; kh\u00f4ng \u0111\u1ec3 g\u1ea7n acid.<\/p>\n<h2>T\u01b0\u01a1ng k\u1ef5<\/h2>\n<p>T\u01b0\u01a1ng k\u1ef5 v\u1edbi iod, acid v\u00e0 mu\u1ed1i calci, ch\u00ec, th\u1ee7y ng\u00e2n, b\u1ea1c. C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m ho\u1ea1t t\u00ednh c\u1ee7a m\u1ed9t s\u1ed1 ch\u1ea5t b\u1ea3o qu\u1ea3n nh\u01b0 bronopol, mu\u1ed1i phenylth\u1ee7y ng\u00e2n v\u00e0 thiomersal.<\/p>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>Quy m\u00f4 c\u00f4ng nghi\u1ec7p ch\u1ee7 y\u1ebfu t\u1eeb n\u01b0\u1edbc th\u1ea3i s\u1ea3n xu\u1ea5t natri sulfid ho\u1eb7c thu\u1ed1c nhu\u1ed9m l\u01b0u hu\u1ef3nh. Quy m\u00f4 nh\u1ecf: \u0111un s\u00f4i dung d\u1ecbch natri sulfit v\u1edbi l\u01b0u hu\u1ef3nh.<\/p>\n<h2>An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n<ul>\n<li>Ngo\u00e0i r\u1ed1i lo\u1ea1n th\u1ea9m th\u1ea5u, natri thiosulfat t\u01b0\u01a1ng \u0111\u1ed1i kh\u00f4ng \u0111\u1ed9c; \u0111\u1ed9c v\u1eeba qua \u0111\u01b0\u1eddng d\u01b0\u1edbi da; k\u00edch \u1ee9ng nh\u1eb9 h\u00f4 h\u1ea5p v\u00e0 da. Li\u1ec1u u\u1ed1ng l\u1edbn g\u00e2y t\u1ea9y x\u1ed5.<\/li>\n<li>WHO \u0111\u1eb7t ADI t\u1edbi 0,7 mg\/kg th\u1ec3 tr\u1ecdng (t\u00ednh theo SO<sub>2<\/sub>).<\/li>\n<li>LD<sub>50<\/sub> (chu\u1ed9t nh\u1eaft, ph\u00fac m\u1ea1c): 5,6 g\/kg; (chu\u1ed9t nh\u1eaft, t\u0129nh m\u1ea1ch): 2,4 g\/kg.<\/li>\n<li>\u0110eo k\u00ednh; n\u00ean \u0111eo g\u0103ng khi ti\u1ebfp x\u00fac k\u00e9o d\u00e0i. \u0110un t\u1edbi ph\u00e2n h\u1ee7y sinh oxyd l\u01b0u hu\u1ef3nh.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n<ul>\n<li>GRAS.<\/li>\n<li>C\u00f3 trong FDA Inactive Ingredients Database (dung d\u1ecbch t\u0129nh m\u1ea1ch; dung d\u1ecbch, h\u1ed7n d\u1ecbch nh\u1ecf m\u1eaft; nang, dung d\u1ecbch, vi\u00ean u\u1ed1ng) v\u00e0 Canadian Natural Health Products Ingredients Database.<\/li>\n<li>C\u00f3 chuy\u00ean lu\u1eadn trong BP, JP, Ph.Eur., USP-NF; c\u00f3 ti\u00eau chu\u1ea9n trong Food Chemicals Codex.<\/li>\n<\/ul>\n<h2>Ch\u1ea5t li\u00ean quan<\/h2>\n<p>Xem th\u00eam natri metabisulfit, natri sulfit, natri formaldehyd sulfoxylat.<\/p>\n<p><strong>Ghi ch\u00fa:<\/strong> natri thiosulfat c\u00f2n l\u00e0 ho\u1ea1t ch\u1ea5t (gi\u1ea3i \u0111\u1ed9c cyanid\u2026) \u2013 c\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. S\u1ed1 EINECS 231-867-5; PubChem CID 24477 (khan), 61475 (pentahydrat).<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<p>N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn <em>Sodium Thiosulfate<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). <em>Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) &amp; American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n<p><em>\u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n<p><em>L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Natri thiosulfat \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a cho thu\u1ed1c nh\u1ecf m\u1eaft, ti\u00eam, u\u1ed1ng Natri thiosulfat (Na2S2O3) th\u01b0\u1eddng \u1edf d\u1ea1ng pentahydrat, tinh th\u1ec3 ho\u1eb7c b\u1ed9t k\u1ebft tinh kh\u00f4ng m\u00e0u, kh\u00f4ng m\u00f9i. Trong b\u00e0o ch\u1ebf, natri thiosulfat l\u00e0 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a cho thu\u1ed1c nh\u1ecf m\u1eaft, thu\u1ed1c ti\u00eam t\u0129nh m\u1ea1ch v\u00e0 thu\u1ed1c u\u1ed1ng. Th\u00f4ng tin nhanh T\u00ean [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3659,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3660","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-thiosulfat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-thiosulfat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-thiosulfat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-thiosulfat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-thiosulfat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-thiosulfat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-thiosulfat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-thiosulfat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Natri thiosulfat \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a cho thu\u1ed1c nh\u1ecf m\u1eaft, ti\u00eam, u\u1ed1ng Natri thiosulfat (Na2S2O3) th\u01b0\u1eddng \u1edf d\u1ea1ng pentahydrat, tinh th\u1ec3 ho\u1eb7c b\u1ed9t k\u1ebft tinh kh\u00f4ng m\u00e0u, kh\u00f4ng m\u00f9i. Trong b\u00e0o ch\u1ebf, natri thiosulfat l\u00e0 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a cho thu\u1ed1c nh\u1ecf m\u1eaft, thu\u1ed1c ti\u00eam t\u0129nh m\u1ea1ch v\u00e0 thu\u1ed1c u\u1ed1ng. Th\u00f4ng tin nhanh T\u00ean&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3660","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3660"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3660\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3659"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3660"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3660"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3660"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}