{"id":3658,"date":"2026-09-29T09:30:54","date_gmt":"2026-09-29T02:30:54","guid":{"rendered":"https:\/\/cpc1.vn\/natri-stearat\/"},"modified":"2026-09-29T12:09:09","modified_gmt":"2026-09-29T05:09:09","slug":"natri-stearat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/natri-stearat\/","title":{"rendered":"Natri stearat \u2013 ch\u1ea5t nh\u0169 h\u00f3a, l\u00e0m c\u1ee9ng, t\u1ea1o gel, t\u00e1 d\u01b0\u1ee3c tr\u01a1n"},"content":{"rendered":"

Natri stearat \u2013 ch\u1ea5t nh\u0169 h\u00f3a, l\u00e0m c\u1ee9ng, t\u1ea1o gel, t\u00e1 d\u01b0\u1ee3c tr\u01a1n<\/h1>\n

Natri stearat<\/strong> l\u00e0 x\u00e0 ph\u00f2ng natri c\u1ee7a acid stearic (th\u1ef1c t\u1ebf l\u00e0 h\u1ed7n h\u1ee3p natri stearat v\u00e0 natri palmitat), d\u1ea1ng b\u1ed9t m\u1ecbn tr\u1eafng ho\u1eb7c h\u01a1i v\u00e0ng, s\u1edd tr\u01a1n, m\u00f9i m\u1ee1 nh\u1eb9. Trong b\u00e0o ch\u1ebf, natri stearat l\u00e0 ch\u1ea5t nh\u0169 h\u00f3a<\/strong>, ch\u1ea5t l\u00e0m c\u1ee9ng<\/strong>, ch\u1ea5t t\u1ea1o gel<\/strong>, t\u00e1 d\u01b0\u1ee3c tr\u01a1n<\/strong>, t\u00e1 d\u01b0\u1ee3c \u0111i\u1ec1u h\u00f2a ch\u1ea3y<\/strong> v\u00e0 t\u00e1c nh\u00e2n \u0111i\u1ec1u ch\u1ec9nh gi\u1ea3i ph\u00f3ng<\/strong>.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nNatri octadecanoat, mu\u1ed1i natri c\u1ee7a acid stearic, natrii stearas<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n822-16-2<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC18<\/sub>H35<\/sub>NaO2<\/sub> \u2013 306,5<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t nh\u0169 h\u00f3a, t\u1ea1o gel, \u0111i\u1ec1u h\u00f2a ch\u1ea3y, \u0111i\u1ec1u ch\u1ec9nh gi\u1ea3i ph\u00f3ng, l\u00e0m c\u1ee9ng, t\u00e1 d\u01b0\u1ee3c tr\u01a1n vi\u00ean n\u00e9n\/vi\u00ean nang<\/td>\n<\/tr>\n
D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nBP, Ph.Eur., USP-NF; c\u00f3 ti\u00eau chu\u1ea9n trong JPE<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • Ch\u1ea5t nh\u0169 h\u00f3a v\u00e0 l\u00e0m c\u1ee9ng trong kem v\u00e0 ch\u1ebf ph\u1ea9m tr\u1ef1c tr\u00e0ng (thu\u1ed1c \u0111\u1ea1n glycerin USP).<\/li>\n
  • T\u00e1 d\u01b0\u1ee3c tr\u01a1n cho vi\u00ean n\u00e9n gi\u1ea3i ph\u00f3ng t\u1ee9c th\u00ec v\u00e0 nang kh\u00e1ng d\u1ecbch v\u1ecb; t\u00e1 d\u01b0\u1ee3c \u0111i\u1ec1u h\u00f2a ch\u1ea3y v\u00e0 \u0111i\u1ec1u ch\u1ec9nh gi\u1ea3i ph\u00f3ng trong vi\u00ean n\u00e9n; d\u00f9ng b\u00e0o ch\u1ebf vi nh\u0169 t\u01b0\u01a1ng.<\/li>\n
  • D\u1ea1ng th\u1ecfi r\u1eafn natri stearat ch\u1ee9a vitamin, ch\u1ea5t kh\u00e1ng n\u1ea5m, ch\u1ea5t g\u00e2y t\u00ea t\u1ea1i ch\u1ed7 \u0111\u00e3 \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u nhi\u1ec1u \u2013 hi\u1ec7u qu\u1ea3 t\u01b0\u01a1ng \u0111\u01b0\u01a1ng thu\u1ed1c m\u1ee1, \u1ed5n \u0111\u1ecbnh t\u1ed1t trong 18 th\u00e1ng.<\/li>\n
  • Ch\u1ea5t t\u1ea1o gel cho l\u0103n kh\u1eed m\u00f9i d\u1ea1ng th\u1ecfi; d\u00f9ng trong m\u1ef9 ph\u1ea9m, d\u1ea7u g\u1ed9i, s\u1eefa t\u1eafm t\u1ea1o b\u1ecdt.<\/li>\n
  • Nghi\u00ean c\u1ee9u: b\u1ed5 sung v\u00e0o b\u1ed9t h\u00edt vi h\u1ea1t tobramycin (\u1ea3nh h\u01b0\u1edfng tr\u1ef1c ti\u1ebfp t\u1edbi hi\u1ec7u n\u0103ng kh\u00ed dung, kh\u00f4ng \u0111\u1ed9c t\u1ebf b\u00e0o ph\u1ed5i); n\u1ec1n thu\u1ed1c m\u1ee1 d\u1ea7u d\u00f9ng nh\u00e3n khoa.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • B\u1ed9t m\u1ecbn tr\u1eafng ho\u1eb7c h\u01a1i v\u00e0ng, tr\u01a1n nh\u1eddn, m\u00f9i m\u1ee1 nh\u1eb9.<\/li>\n
    • USP-NF: t\u1ed5ng natri stearat v\u00e0 natri palmitat \u2265 90%, acid stearic \u2265 40% (trong ph\u1ea7n acid b\u00e9o). Ch\u1ec9 s\u1ed1 acid 195\u2013211; Ph.Eur.: natri 7,4\u20138,5%, nhi\u1ec7t \u0111\u1ed9 \u0111\u00f4ng \u0111\u1eb7c \u2265 53 \u00b0C.<\/li>\n
    • pH dung d\u1ecbch 5%: 10\u201311; \u0111i\u1ec3m ch\u1ea3y 205\u2013255 \u00b0C; t\u1ef7 tr\u1ecdng ri\u00eang 1,02.<\/li>\n
    • \u0110\u1ed9 tan: h\u01a1i tan trong n\u01b0\u1edbc, glycol v\u00e0 ethanol 96% \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng, tan d\u1ec5 khi \u0111un n\u00f3ng.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t, tr\u00e1nh \u00e1nh s\u00e1ng, xa ngu\u1ed3n l\u1eeda.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi acid m\u1ea1nh v\u00e0 ch\u1ea5t oxy h\u00f3a.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Cho acid stearic ph\u1ea3n \u1ee9ng v\u1edbi l\u01b0\u1ee3ng \u0111\u1eb3ng mol natri hydroxyd.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
        \n
      • Nh\u00ecn chung kh\u00f4ng k\u00edch \u1ee9ng da, d\u00f9 \u0111\u00e3 ghi nh\u1eadn k\u00edch \u1ee9ng khi ti\u1ebfp x\u00fac k\u00e9o d\u00e0i. Nu\u1ed1t c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n n\u00f4n, n\u00f4n, ti\u00eau ch\u1ea3y; th\u01b0\u1eddng g\u00e2y k\u00edch \u1ee9ng m\u1eaft tho\u00e1ng qua; k\u00edch \u1ee9ng h\u00f4 h\u1ea5p, c\u00f3 b\u00e1o c\u00e1o hen ngh\u1ec1 nghi\u1ec7p.<\/li>\n
      • Natri stearat g\u00e2y k\u1ebft t\u1eadp ti\u1ec3u c\u1ea7u \u2013 c\u00f3 l\u1ebd l\u00e0 l\u00fd do truy\u1ec1n t\u0129nh m\u1ea1ch g\u00e2y huy\u1ebft kh\u1ed1i lan r\u1ed9ng tr\u00ean ch\u00f3.<\/li>\n
      • LD50<\/sub> (th\u1ecf, qua da): tr\u00ean 3 g\/kg; (chu\u1ed9t c\u1ed1ng, u\u1ed1ng): tr\u00ean 5 g\/kg. LDLo<\/sub> (ch\u00f3, t\u0129nh m\u1ea1ch): 0,01 g\/kg.<\/li>\n
      • Gi\u1edbi h\u1ea1n b\u1ee5i: OSHA 15 mg\/m\u00b3 (b\u1ee5i to\u00e0n ph\u1ea7n); ACGIH 10 mg\/m\u00b3 (stearat). \u0110eo k\u00ednh, g\u0103ng, kh\u1ea9u trang; thao t\u00e1c n\u01a1i th\u00f4ng tho\u00e1ng. \u0110un t\u1edbi ph\u00e2n h\u1ee7y sinh kh\u00f3i \u0111\u1ed9c, d\u1ec5 ch\u00e1y.<\/li>\n<\/ul>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • C\u00f3 trong FDA Inactive Ingredients Database (vi\u00ean n\u00e9n u\u1ed1ng gi\u1ea3i ph\u00f3ng t\u1ee9c th\u00ec v\u00e0 c\u00f3 \u0111i\u1ec1u ch\u1ec9nh); c\u00f3 trong vi\u00ean n\u00e9n v\u00e0 nang kh\u00e1ng d\u1ecbch v\u1ecb l\u01b0u h\u00e0nh t\u1ea1i Anh; c\u00f3 trong Canadian Natural Health Products Ingredients Database.<\/li>\n
        • C\u00f3 chuy\u00ean lu\u1eadn trong BP, Ph.Eur., USP-NF.<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan<\/h2>\n

          Calci stearat, magnesi stearat, k\u1ebdm stearat; xem th\u00eam acid stearic, natri stearyl fumarat.<\/p>\n

          Ghi ch\u00fa:<\/strong> s\u1ed1 EINECS 212-490-5.<\/p>\n

          Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

          N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Sodium Stearate<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

          \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

          L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          Natri stearat \u2013 ch\u1ea5t nh\u0169 h\u00f3a, l\u00e0m c\u1ee9ng, t\u1ea1o gel, t\u00e1 d\u01b0\u1ee3c tr\u01a1n Natri stearat l\u00e0 x\u00e0 ph\u00f2ng natri c\u1ee7a acid stearic (th\u1ef1c t\u1ebf l\u00e0 h\u1ed7n h\u1ee3p natri stearat v\u00e0 natri palmitat), d\u1ea1ng b\u1ed9t m\u1ecbn tr\u1eafng ho\u1eb7c h\u01a1i v\u00e0ng, s\u1edd tr\u01a1n, m\u00f9i m\u1ee1 nh\u1eb9. Trong b\u00e0o ch\u1ebf, natri stearat l\u00e0 ch\u1ea5t nh\u0169 h\u00f3a, ch\u1ea5t l\u00e0m […]<\/p>\n","protected":false},"author":1,"featured_media":3657,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3658","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-stearat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-stearat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-stearat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-stearat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-stearat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-stearat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-stearat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-stearat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Natri stearat \u2013 ch\u1ea5t nh\u0169 h\u00f3a, l\u00e0m c\u1ee9ng, t\u1ea1o gel, t\u00e1 d\u01b0\u1ee3c tr\u01a1n Natri stearat l\u00e0 x\u00e0 ph\u00f2ng natri c\u1ee7a acid stearic (th\u1ef1c t\u1ebf l\u00e0 h\u1ed7n h\u1ee3p natri stearat v\u00e0 natri palmitat), d\u1ea1ng b\u1ed9t m\u1ecbn tr\u1eafng ho\u1eb7c h\u01a1i v\u00e0ng, s\u1edd tr\u01a1n, m\u00f9i m\u1ee1 nh\u1eb9. Trong b\u00e0o ch\u1ebf, natri stearat l\u00e0 ch\u1ea5t nh\u0169 h\u00f3a, ch\u1ea5t l\u00e0m…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3658","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3658"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3658\/revisions"}],"predecessor-version":[{"id":3902,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3658\/revisions\/3902"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3657"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3658"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3658"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3658"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}