{"id":3653,"date":"2026-09-29T09:29:22","date_gmt":"2026-09-29T02:29:22","guid":{"rendered":"https:\/\/cpc1.vn\/natri-formaldehyd-sulfoxylat\/"},"modified":"2026-09-29T09:29:22","modified_gmt":"2026-09-29T02:29:22","slug":"natri-formaldehyd-sulfoxylat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/natri-formaldehyd-sulfoxylat\/","title":{"rendered":"Natri formaldehyd sulfoxylat (Rongalit) \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a tan trong n\u01b0\u1edbc cho thu\u1ed1c ti\u00eam"},"content":{"rendered":"

Natri formaldehyd sulfoxylat (Rongalit) \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a tan trong n\u01b0\u1edbc cho thu\u1ed1c ti\u00eam<\/h1>\n

Natri formaldehyd sulfoxylat<\/strong> (Rongalit, natri hydroxymethansulfinat) l\u00e0 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a tan trong n\u01b0\u1edbc<\/strong>, th\u01b0\u1eddng d\u00f9ng \u1edf d\u1ea1ng dihydrat. Trong b\u00e0o ch\u1ebf, ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c d\u00f9ng trong thu\u1ed1c ti\u00eam<\/strong> v\u1edbi n\u1ed3ng \u0111\u1ed9 t\u1edbi 0,1% (kl\/tt) trong ch\u1ebf ph\u1ea9m cu\u1ed1i c\u00f9ng d\u00f9ng cho ng\u01b0\u1eddi b\u1ec7nh.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nRongalit, natri hydroxymethansulfinat, formaldehyd hydrosulfit, mu\u1ed1i natri c\u1ee7a acid formaldehydsulfoxylic<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n149-44-0 (khan); 6035-47-8 (dihydrat)<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nCH3<\/sub>NaO3<\/sub>S \u2013 118,09; CH3<\/sub>NaO3<\/sub>S\u00b72H2<\/sub>O \u2013 154,11<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t ch\u1ed1ng oxy h\u00f3a<\/td>\n<\/tr>\n
D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nUSP-NF<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • Ch\u1ea5t ch\u1ed1ng oxy h\u00f3a tan trong n\u01b0\u1edbc cho thu\u1ed1c ti\u00eam b\u1eafp, t\u0129nh m\u1ea1ch, d\u01b0\u1edbi da, t\u1edbi 0,1% (kl\/tt) trong ch\u1ebf ph\u1ea9m cu\u1ed1i.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • M\u1edbi \u0111i\u1ec1u ch\u1ebf l\u00e0 tinh th\u1ec3 tr\u1eafng, kh\u00f4ng m\u00f9i; \u0111\u1ec3 l\u00e2u nhanh ch\u00f3ng c\u00f3 m\u00f9i t\u1ecfi \u0111\u1eb7c tr\u01b0ng.<\/li>\n
    • pH dung d\u1ecbch 2%: 9,5\u201310,5; d\u1ea1ng dihydrat n\u00f3ng ch\u1ea3y 64\u201368 \u00b0C.<\/li>\n
    • USP-NF: h\u00e0m l\u01b0\u1ee3ng (t\u00ednh theo SO2<\/sub>) 45,5\u201354,5%; c\u00f3 th\u1ec3 ch\u1ee9a ch\u1ea5t \u1ed5n \u0111\u1ecbnh th\u00edch h\u1ee3p nh\u01b0 natri carbonat.<\/li>\n
    • \u0110\u1ed9 tan: d\u1ec5 tan trong n\u01b0\u1edbc; h\u01a1i tan trong ethanol, cloroform, ether, benzen.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, ch\u1ed1ng \u00e1nh s\u00e1ng, \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng c\u00f3 ki\u1ec3m so\u00e1t (15\u201330 \u00b0C).<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t oxy h\u00f3a m\u1ea1nh; b\u1ecb acid lo\u00e3ng ph\u00e2n h\u1ee7y.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      \u0110i\u1ec1u ch\u1ebf t\u1eeb natri dithionit v\u00e0 formaldehyd trong n\u01b0\u1edbc.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
        \n
      • \u0110\u1ed9c t\u00ednh ch\u01b0a \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u \u0111\u1ea7y \u0111\u1ee7; tuy v\u1eady \u0111\u00e3 \u0111\u01b0\u1ee3c d\u00f9ng trong thu\u1ed1c ti\u00eam t\u1edbi 0,1%. \u0110\u1ed9c v\u1eeba khi nu\u1ed1t; \u0111un t\u1edbi ph\u00e2n h\u1ee7y sinh kh\u00f3i \u0111\u1ed9c SO2<\/sub> v\u00e0 natri oxyd.<\/li>\n
      • LD50<\/sub> (chu\u1ed9t nh\u1eaft, u\u1ed1ng): 4 g\/kg; (chu\u1ed9t c\u1ed1ng, u\u1ed1ng v\u00e0 ph\u00fac m\u1ea1c): tr\u00ean 2 g\/kg.<\/li>\n
      • C\u00f3 th\u1ec3 k\u00edch \u1ee9ng m\u1eaft, da, \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p v\u00e0 ti\u00eau h\u00f3a; r\u1ea5t n\u00ean \u0111eo k\u00ednh, kh\u1ea9u trang v\u00e0 g\u0103ng.<\/li>\n<\/ul>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • C\u00f3 trong FDA Inactive Ingredients Database (thu\u1ed1c ti\u00eam b\u1eafp, t\u0129nh m\u1ea1ch, d\u01b0\u1edbi da, t\u1edbi 0,1%).<\/li>\n
        • C\u00f3 chuy\u00ean lu\u1eadn trong USP-NF.<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan<\/h2>\n

          K\u1ebdm formaldehyd sulfoxylat<\/strong> (C2<\/sub>H6<\/sub>O6<\/sub>S2<\/sub>Zn, KLPT 256,5; CAS 24887-06-7): ph\u1ee5 gia polymer v\u00e0 d\u1ec7t may. Xem th\u00eam natri metabisulfit, natri sulfit.<\/p>\n

          Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

          N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Sodium Formaldehyde Sulfoxylate<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

          \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

          L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          Natri formaldehyd sulfoxylat (Rongalit) \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a tan trong n\u01b0\u1edbc cho thu\u1ed1c ti\u00eam Natri formaldehyd sulfoxylat (Rongalit, natri hydroxymethansulfinat) l\u00e0 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a tan trong n\u01b0\u1edbc, th\u01b0\u1eddng d\u00f9ng \u1edf d\u1ea1ng dihydrat. Trong b\u00e0o ch\u1ebf, ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c d\u00f9ng trong thu\u1ed1c ti\u00eam v\u1edbi n\u1ed3ng \u0111\u1ed9 t\u1edbi 0,1% (kl\/tt) trong ch\u1ebf ph\u1ea9m cu\u1ed1i c\u00f9ng […]<\/p>\n","protected":false},"author":1,"featured_media":3652,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3653","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-formaldehyd-sulfoxylat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-formaldehyd-sulfoxylat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-formaldehyd-sulfoxylat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-formaldehyd-sulfoxylat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-formaldehyd-sulfoxylat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-formaldehyd-sulfoxylat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-formaldehyd-sulfoxylat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-formaldehyd-sulfoxylat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Natri formaldehyd sulfoxylat (Rongalit) \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a tan trong n\u01b0\u1edbc cho thu\u1ed1c ti\u00eam Natri formaldehyd sulfoxylat (Rongalit, natri hydroxymethansulfinat) l\u00e0 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a tan trong n\u01b0\u1edbc, th\u01b0\u1eddng d\u00f9ng \u1edf d\u1ea1ng dihydrat. Trong b\u00e0o ch\u1ebf, ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c d\u00f9ng trong thu\u1ed1c ti\u00eam v\u1edbi n\u1ed3ng \u0111\u1ed9 t\u1edbi 0,1% (kl\/tt) trong ch\u1ebf ph\u1ea9m cu\u1ed1i c\u00f9ng…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3653","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3653"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3653\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3652"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3653"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3653"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}