{"id":3649,"date":"2026-09-29T09:27:33","date_gmt":"2026-09-29T02:27:33","guid":{"rendered":"https:\/\/cpc1.vn\/pyroxylin-collodion\/"},"modified":"2026-09-29T09:27:33","modified_gmt":"2026-09-29T02:27:33","slug":"pyroxylin-collodion","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/pyroxylin-collodion\/","title":{"rendered":"Pyroxylin (cellulose nitrat) \u2013 t\u00e1c nh\u00e2n t\u1ea1o m\u00e0ng trong collodion"},"content":{"rendered":"

Pyroxylin (cellulose nitrat) \u2013 t\u00e1c nh\u00e2n t\u1ea1o m\u00e0ng trong collodion<\/h1>\n

Pyroxylin<\/strong> (cellulose nitrat, nitrocellulose) l\u00e0 h\u1ed7n h\u1ee3p c\u00e1c nitrat c\u1ee7a cellulose, trung b\u00ecnh 2\u20132,5 nh\u00f3m nitrat m\u1ed7i \u0111\u01a1n v\u1ecb \u0111\u01b0\u1eddng. Trong b\u00e0o ch\u1ebf, pyroxylin l\u00e0 t\u00e1c nh\u00e2n t\u1ea1o m\u00e0ng<\/strong> trong collodion<\/strong> \u2013 ch\u1ebf ph\u1ea9m l\u1ecfng b\u00f4i ngo\u00e0i da, khi dung m\u00f4i bay h\u01a1i \u0111\u1ec3 l\u1ea1i m\u00e0ng trong su\u1ed1t, k\u00edn, d\u1ebbo.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nCellulose nitrat, nitrocellulose, celloidin, colloxylin, collodion wool, b\u00f4ng thu\u1ed1c s\u00fang tan<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n9004-70-0<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c<\/td>\n(C12<\/sub>H16<\/sub>N4<\/sub>O18<\/sub>)n<\/sub> \u2013 (504,3)n<\/sub><\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nT\u00e1c nh\u00e2n t\u1ea1o m\u00e0ng<\/td>\n<\/tr>\n
D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nBP, JP, USP-NF (Pyroxylin); collodion v\u00e0 collodion d\u1ebbo c\u00f3 chuy\u00ean lu\u1eadn trong BP, USP-NF<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Collodion<\/h2>\n
    \n
  • Collodion USP:<\/strong> pyroxylin 40 g, ether 750 mL, ethanol 250 mL \u2013 th\u00eam ethanol v\u00e0 ether v\u00e0o pyroxylin, th\u1ec9nh tho\u1ea3ng l\u1eafc t\u1edbi khi tan.<\/li>\n
  • Collodion BP<\/strong> (\u0111\u1ec3 pha collodion d\u1ebbo): 100 g pyroxylin trong 900 mL h\u1ed7n h\u1ee3p ether \u2013 ethanol 90% (3:1).<\/li>\n
  • Khi b\u00f4i, dung m\u00f4i bay h\u01a1i t\u1ea1o m\u00e0ng trong, k\u00edn, d\u1ebbo. Ch\u1ea5t h\u00f3a d\u1ebbo (d\u1ea7u th\u1ea7u d\u1ea7u) t\u1ea1o \u0111\u1ed9 d\u1ebbo; long n\u00e3o l\u00e0m m\u00e0ng kh\u00f4ng th\u1ea5m n\u01b0\u1edbc.<\/li>\n
  • C\u00f4ng d\u1ee5ng: che v\u1ebft c\u1eaft, tr\u1ea7y x\u01b0\u1edbc nh\u1ecf; b\u1ecbt k\u00edn v\u1ebft th\u01b0\u01a1ng \u0111\u00e3 l\u00e0nh m\u1ed9t ph\u1ea7n; gi\u1eef ho\u1ea1t ch\u1ea5t h\u00f2a tan (v\u00ed d\u1ee5 acid salicylic) ti\u1ebfp x\u00fac l\u00e2u v\u1edbi da. C\u00f2n d\u00f9ng l\u00e0m m\u00e0ng m\u00f4 h\u00ecnh, b\u0103ng che catheter t\u0129nh m\u1ea1ch trung t\u00e2m.<\/li>\n
  • Pyroxylin c\u0169ng \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u \u0111\u1ec3 t\u1ea1o vi nang v\u00e0 h\u1ec7 gi\u1ea3i ph\u00f3ng c\u00f3 ki\u1ec3m so\u00e1t \u0111\u00e1p \u1ee9ng nhi\u1ec7t.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Pyroxylin: h\u1ea1t h\u00ecnh kh\u1ed1i, v\u1ea3y tr\u1eafng, ho\u1eb7c d\u1ea1ng s\u1ee3i gi\u1ed1ng b\u00f4ng th\u1ea5m nh\u01b0ng th\u00f4 v\u00e0 b\u1edf h\u01a1n; tr\u00f4ng \u1ea9m v\u00e0 r\u1ea5t d\u1ec5 ch\u00e1y. Collodion: ch\u1ea5t l\u1ecfng s\u00e1nh kh\u00f4ng m\u00e0u ho\u1eb7c v\u00e0ng nh\u1ea1t, m\u00f9i ether.<\/li>\n
    • T\u00ednh ch\u1ea5t ph\u1ee5 thu\u1ed9c nhi\u1ec1u v\u00e0o s\u1ed1 nh\u00f3m nitrat \u0111\u01b0a v\u00e0o; BP y\u00eau c\u1ea7u nit\u01a1 11,7\u201312,2%.<\/li>\n
    • Pyroxylin d\u1ec5 tan trong aceton; tan trong methanol, amyl acetat, acid acetic b\u0103ng; r\u1ea5t kh\u00f3 tan trong diethyl ether; kh\u00f4ng tan trong n\u01b0\u1edbc. Collodion kh\u00f4ng tan trong n\u01b0\u1edbc \u2013 th\u00eam n\u01b0\u1edbc c\u00f3 th\u1ec3 t\u1ee7a pyroxylin.<\/li>\n
    • Collodion: t\u1ef7 tr\u1ecdng ri\u00eang 0,765\u20130,795; s\u00f4i kho\u1ea3ng 38 \u00b0C; t\u1ef1 b\u1ed1c ch\u00e1y 180\u2013190 \u00b0C; gi\u1edbi h\u1ea1n n\u1ed5 2\u201336%.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n
        \n
      • Pyroxylin: \u0111\u00f3ng l\u1ecfng, tr\u00e1nh \u00e1nh s\u00e1ng, kh\u00f4ng qu\u00e1 15 \u00b0C, xa l\u1eeda; bao b\u00ec ph\u1ea3i thi\u1ebft k\u1ebf \u0111\u1ec3 v\u1ee1 n\u1ebfu \u00e1p su\u1ea5t trong \u0111\u1ea1t 1400 kPa. L\u01b0\u1ee3ng ch\u1ea5t l\u00e0m \u1ea9m kh\u00f4ng \u0111\u01b0\u1ee3c d\u01b0\u1edbi 25% (kl\/kl) \u2013 n\u1ebfu th\u1ea5p h\u01a1n ph\u1ea3i l\u00e0m \u1ea9m l\u1ea1i ho\u1eb7c d\u00f9ng ngay \u0111\u1ec3 pha collodion. Nhi\u1ec7t ho\u1eb7c \u00e1nh s\u00e1ng ph\u00e2n h\u1ee7y pyroxylin, gi\u1ea3i ph\u00f3ng h\u01a1i acid nitr\u01a1.<\/li>\n
      • Collodion: bao b\u00ec k\u00edn kh\u00ed, kh\u00f4ng qu\u00e1 30 \u00b0C, xa l\u1eeda; nh\u00e3n ph\u1ea3i c\u1ea3nh b\u00e1o r\u1ea5t d\u1ec5 ch\u00e1y. Ph\u00e2n h\u1ee7y nhi\u1ec7t sinh kh\u00f3i \u0111\u1ed9c oxyd carbon, oxyd nit\u01a1.<\/li>\n<\/ul>\n

        T\u01b0\u01a1ng k\u1ef5<\/h2>\n

        Pyroxylin t\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t oxy h\u00f3a. Collodion t\u01b0\u01a1ng k\u1ef5 v\u1edbi acetyl peroxyd, bromoazid, clor, ch\u1ea5t oxy h\u00f3a m\u1ea1nh, acid m\u1ea1nh, base m\u1ea1nh v\u00e0 amin; d\u1ec5 t\u1ea1o h\u1ed7n h\u1ee3p n\u1ed5 v\u1edbi kh\u00f4ng kh\u00ed.<\/p>\n

        S\u1ea3n xu\u1ea5t<\/h2>\n

        Nitrat h\u00f3a b\u1ed9t g\u1ed7 ho\u1eb7c x\u01a1 b\u00f4ng \u0111\u00e3 kh\u1eed ch\u1ea5t b\u00e9o b\u1eb1ng h\u1ed7n h\u1ee3p acid nitric \u2013 acid sulfuric. S\u1ea3n ph\u1ea9m ph\u1ea3i \u0111\u01b0\u1ee3c l\u00e0m \u1ea9m b\u1eb1ng \u00edt nh\u1ea5t 25% (kl\/kl) isopropanol ho\u1eb7c c\u1ed3n c\u00f4ng nghi\u1ec7p.<\/p>\n

        An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
          \n
        • Pyroxylin c\u00f3 th\u1ec3 g\u00e2y d\u1ecb \u1ee9ng da. Collodion k\u00edch \u1ee9ng da, m\u1eaft, \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p; kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m l\u1edbp bao vi\u00ean ho\u1eb7c bao \u0111\u01b0\u1eddng v\u00ec \u0111\u1ed9c v\u00e0 kh\u00f4ng tan trong \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/li>\n
        • Pyroxylin r\u1ea5t d\u1ec5 ch\u00e1y; \u0111\u1eb7c bi\u1ec7t c\u1ea9n th\u1eadn khi l\u00e0m kh\u00f4 v\u00ec s\u1ea3n ph\u1ea9m kh\u00f4 d\u1ec5 n\u1ed5, nh\u1ea1y va \u0111\u1eadp v\u00e0 ma s\u00e1t. Collodion d\u1ea1ng l\u1ecfng v\u00e0 h\u01a1i r\u1ea5t d\u1ec5 ch\u00e1y, d\u1ec5 n\u1ed5 \u2013 tr\u00e1nh nhi\u1ec7t, tia l\u1eeda, ng\u1ecdn l\u1eeda; ch\u1ec9 d\u00f9ng n\u01a1i th\u00f4ng tho\u00e1ng.<\/li>\n<\/ul>\n

          T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
            \n
          • C\u00f3 trong gel, dung d\u1ecbch v\u00e0 thu\u1ed1c s\u01a1n b\u00f4i ngo\u00e0i l\u01b0u h\u00e0nh t\u1ea1i Anh; c\u00f3 trong Canadian Natural Health Products Ingredients Database.<\/li>\n<\/ul>\n

            Ch\u1ea5t li\u00ean quan<\/h2>\n

            Collodion d\u1ebbo<\/strong> (BP, USP-NF): USP g\u1ed3m long n\u00e3o 20 g, d\u1ea7u th\u1ea7u d\u1ea7u 30 g, collodion v\u1eeba \u0111\u1ee7 1000 g; BP g\u1ed3m colophan 25 g, d\u1ea7u th\u1ea7u d\u1ea7u nguy\u00ean ch\u1ea5t 25 g, collodion v\u1eeba \u0111\u1ee7 1000 mL. H\u00e0m l\u01b0\u1ee3ng ethanol 20\u201325%. B\u1ea3o qu\u1ea3n k\u00edn kh\u00ed, kh\u00f4ng qu\u00e1 30 \u00b0C, xa l\u1eeda; c\u00f3 th\u1ec3 t\u1ea1o peroxyd d\u1ec5 n\u1ed5 khi g\u1eb7p \u00e1nh s\u00e1ng v\u00e0 kh\u00f4ng kh\u00ed. H\u01a1i c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t; \u0111\u00e3 ghi nh\u1eadn vi\u00eam da ti\u1ebfp x\u00fac d\u1ecb \u1ee9ng do colophan trong collodion d\u1ebbo BP. BP quy \u0111\u1ecbnh khi k\u00ea “collodion” th\u00ec c\u1ea5p collodion d\u1ebbo.<\/p>\n

            Ghi ch\u00fa:<\/strong> c\u00e1c ch\u1ebf ph\u1ea9m collodion ch\u1ee9a ho\u1ea1t ch\u1ea5t (acid salicylic\u2026) l\u00e0 thu\u1ed1c \u2013 c\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/p>\n

            Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

            N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Pyroxylin<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

            \u1ea2nh minh h\u1ecda: thi\u1ebft k\u1ebf c\u1ee7a CPC1.<\/em><\/p>\n

            L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

            Pyroxylin (cellulose nitrat) \u2013 t\u00e1c nh\u00e2n t\u1ea1o m\u00e0ng trong collodion Pyroxylin (cellulose nitrat, nitrocellulose) l\u00e0 h\u1ed7n h\u1ee3p c\u00e1c nitrat c\u1ee7a cellulose, trung b\u00ecnh 2\u20132,5 nh\u00f3m nitrat m\u1ed7i \u0111\u01a1n v\u1ecb \u0111\u01b0\u1eddng. Trong b\u00e0o ch\u1ebf, pyroxylin l\u00e0 t\u00e1c nh\u00e2n t\u1ea1o m\u00e0ng trong collodion \u2013 ch\u1ebf ph\u1ea9m l\u1ecfng b\u00f4i ngo\u00e0i da, khi dung m\u00f4i bay h\u01a1i \u0111\u1ec3 l\u1ea1i […]<\/p>\n","protected":false},"author":1,"featured_media":3648,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3649","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/pyroxylin-collodion.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/pyroxylin-collodion-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/pyroxylin-collodion-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/pyroxylin-collodion-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/pyroxylin-collodion-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/pyroxylin-collodion.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/pyroxylin-collodion.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/pyroxylin-collodion-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Pyroxylin (cellulose nitrat) \u2013 t\u00e1c nh\u00e2n t\u1ea1o m\u00e0ng trong collodion Pyroxylin (cellulose nitrat, nitrocellulose) l\u00e0 h\u1ed7n h\u1ee3p c\u00e1c nitrat c\u1ee7a cellulose, trung b\u00ecnh 2\u20132,5 nh\u00f3m nitrat m\u1ed7i \u0111\u01a1n v\u1ecb \u0111\u01b0\u1eddng. Trong b\u00e0o ch\u1ebf, pyroxylin l\u00e0 t\u00e1c nh\u00e2n t\u1ea1o m\u00e0ng trong collodion \u2013 ch\u1ebf ph\u1ea9m l\u1ecfng b\u00f4i ngo\u00e0i da, khi dung m\u00f4i bay h\u01a1i \u0111\u1ec3 l\u1ea1i…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3649","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3649"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3649\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3648"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3649"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3649"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3649"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}