{"id":3645,"date":"2026-09-29T09:27:20","date_gmt":"2026-09-29T02:27:20","guid":{"rendered":"https:\/\/cpc1.vn\/dau-rum\/"},"modified":"2026-09-29T09:27:20","modified_gmt":"2026-09-29T02:27:20","slug":"dau-rum","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/dau-rum\/","title":{"rendered":"D\u1ea7u rum (d\u1ea7u h\u1ed3ng hoa) \u2013 t\u00e1 d\u01b0\u1ee3c d\u1ea7u cho thu\u1ed1c u\u1ed1ng, b\u00f4i, nh\u0169 t\u01b0\u01a1ng lipid ti\u00eam"},"content":{"rendered":"

D\u1ea7u rum (d\u1ea7u h\u1ed3ng hoa) \u2013 t\u00e1 d\u01b0\u1ee3c d\u1ea7u cho thu\u1ed1c u\u1ed1ng, b\u00f4i, nh\u0169 t\u01b0\u01a1ng lipid ti\u00eam<\/h1>\n

D\u1ea7u rum<\/strong> (d\u1ea7u h\u1ed3ng hoa, safflower oil) l\u00e0 d\u1ea7u b\u00e9o \u00e9p ho\u1eb7c chi\u1ebft t\u1eeb h\u1ea1t c\u00e2y rum (Carthamus tinctorius<\/em>) r\u1ed3i tinh ch\u1ebf; ch\u1ea5t l\u1ecfng trong, s\u00e1nh, v\u00e0ng t\u1edbi v\u00e0ng nh\u1ea1t, m\u00f9i th\u1ef1c v\u1eadt nh\u1eb9. Trong b\u00e0o ch\u1ebf, d\u1ea7u rum ch\u1ee7 y\u1ebfu l\u00e0 t\u00e1 d\u01b0\u1ee3c d\u1ea7u<\/strong> v\u00e0 dung m\u00f4i<\/strong> cho thu\u1ed1c u\u1ed1ng v\u00e0 b\u00f4i, \u0111\u1ed3ng th\u1eddi l\u00e0 th\u00e0nh ph\u1ea7n c\u1ee7a nh\u0169 t\u01b0\u01a1ng lipid ti\u00eam truy\u1ec1n<\/strong>.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nD\u1ea7u h\u1ed3ng hoa, d\u1ea7u rum tinh ch\u1ebf, carthami oleum raffinatum<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n8001-23-8<\/td>\n<\/tr>\n
Th\u00e0nh ph\u1ea7n<\/td>\nTriglycerid; Ph.Eur. chia 2 lo\u1ea1i: lo\u1ea1i I (t\u1eeb C. tinctorius<\/em>, gi\u00e0u acid linoleic) v\u00e0 lo\u1ea1i II (t\u1eeb gi\u1ed1ng lai, gi\u00e0u acid oleic)<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t l\u00e0m m\u1ec1m, t\u00e1 d\u01b0\u1ee3c d\u1ea7u, dung m\u00f4i<\/td>\n<\/tr>\n
D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nBP (Refined Safflower Oil), Ph.Eur. (Safflower Oil, Refined), USP-NF (Safflower Oil); c\u00f3 ti\u00eau chu\u1ea9n trong JPE<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Th\u00e0nh ph\u1ea7n acid b\u00e9o (Ph.Eur.)<\/h2>\n\n\n\n\n\n\n\n\n
Acid b\u00e9o<\/th>\nLo\u1ea1i I<\/th>\nLo\u1ea1i II<\/th>\n<\/tr>\n<\/thead>\n
Acid linoleic<\/td>\n68,0\u201383,0%<\/td>\n7,0\u201323,0%<\/td>\n<\/tr>\n
Acid oleic<\/td>\n8,0\u201321,0%<\/td>\n70,0\u201384,0%<\/td>\n<\/tr>\n
Acid stearic<\/td>\n1,0\u20135,0%<\/td>\n1,0\u20135,0%<\/td>\n<\/tr>\n
Chi\u1ebft su\u1ea5t \/ t\u1ef7 tr\u1ecdng t\u01b0\u01a1ng \u0111\u1ed1i<\/td>\nkho\u1ea3ng 1,476 \/ 0,922<\/td>\nkho\u1ea3ng 1,472 \/ 0,914<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

USP-NF: acid linoleic 72\u201384%, oleic 7\u201342%, stearic 1\u201310%.<\/p>\n

Applications<\/h2>\n
    \n
  • T\u00e1 d\u01b0\u1ee3c d\u1ea7u trong ch\u1ebf ph\u1ea9m u\u1ed1ng v\u00e0 b\u00f4i (lotion b\u00f4i ch\u1ee9a kho\u1ea3ng 3% d\u1ea7u rum \u0111\u00e3 l\u01b0u h\u00e0nh).<\/li>\n
  • Dung m\u00f4i cho nang: m\u1ed9t c\u00f4ng th\u1ee9c nang thu\u1ed1c h\u1ea1 lipid d\u00f9ng d\u1ea7u rum cho sinh kh\u1ea3 d\u1ee5ng cao nh\u1ea5t tr\u00ean ch\u00f3 so v\u1edbi PEG 300 ho\u1eb7c n\u01b0\u1edbc; \u0111\u00e3 l\u00e0m t\u00e1 d\u01b0\u1ee3c cho d\u1ea1ng u\u1ed1ng ch\u1ee9a ch\u1ea5t \u1ee9c ch\u1ebf virus rhinovirus.<\/li>\n
  • Th\u00e0nh ph\u1ea7n nh\u0169 t\u01b0\u01a1ng lipid ti\u00eam truy\u1ec1n dinh d\u01b0\u1ee1ng (v\u00ed d\u1ee5 ph\u1ed1i h\u1ee3p d\u1ea7u rum 5% + d\u1ea7u \u0111\u1eadu n\u00e0nh 5%, ho\u1eb7c 10% + 10%).<\/li>\n
  • Nghi\u00ean c\u1ee9u: oleogel c\u1ea5y gh\u00e9p t\u1ea1o t\u1ea1i ch\u1ed7; t\u00e1 d\u01b0\u1ee3c ti\u00eam d\u01b0\u1edbi da vi h\u1ea1t lysozym li\u1ec1u cao.<\/li>\n
  • M\u1ef9 ph\u1ea9m (x\u00e0 ph\u00f2ng, lotion, kem, s\u1ea3n ph\u1ea9m t\u00f3c); th\u1ef1c ph\u1ea9m (b\u01a1 th\u1ef1c v\u1eadt m\u1ec1m, d\u1ea7u salad, d\u1ea7u \u0103n).<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Ch\u1ea5t l\u1ecfng trong, s\u00e1nh, v\u00e0ng t\u1edbi v\u00e0ng nh\u1ea1t, m\u00f9i th\u1ef1c v\u1eadt nh\u1eb9.<\/li>\n
    • Ch\u1ec9 s\u1ed1 iod 140\u2013150; ch\u1ec9 s\u1ed1 x\u00e0 ph\u00f2ng h\u00f3a 188\u2013194; ch\u1ec9 s\u1ed1 hydroxyl 2,9\u20136,0; chi\u1ebft su\u1ea5t kho\u1ea3ng 1,469\u20131,476; \u0111i\u1ec3m ch\u1edbp ch\u00e1y tr\u00ean 287 \u00b0C. Ch\u1ec9 s\u1ed1 acid d\u01b0\u1ee3c \u0111i\u1ec3n th\u1ea5p h\u01a1n cho lo\u1ea1i d\u00f9ng pha ti\u00eam.<\/li>\n
    • \u0110\u1ed9 tan: tan trong dung m\u00f4i h\u1eefu c\u01a1; tr\u1ed9n l\u1eabn v\u1edbi ether, cloroform, ether d\u1ea7u h\u1ecfa nh\u1eb9; h\u1ea7u nh\u01b0 kh\u00f4ng tan trong ethanol; \u0111\u1ed9 tan trong n\u01b0\u1edbc d\u01b0\u1edbi 0,1%.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n
        \n
      • \u0110\u1ec3 l\u00e2u trong kh\u00f4ng kh\u00ed b\u1ecb \u0111\u1eb7c l\u1ea1i v\u00e0 \u00f4i; nh\u1ea1y s\u00e1ng. B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, \u0111\u1ea7y, tr\u00e1nh \u00e1nh s\u00e1ng.<\/li>\n
      • Nh\u0169 t\u01b0\u01a1ng lipid ti\u00eam ch\u1ee9a d\u1ea7u rum b\u1ecb ch\u1ea5t \u0111i\u1ec7n ly l\u00e0m m\u1ea5t \u1ed5n \u0111\u1ecbnh; th\u00eam dimethyl sulfoxid 10% g\u00e2y h\u1ee3p gi\u1ecdt n\u1eb7ng sau 3\u20135 ng\u00e0y (5% sau 10 ng\u00e0y). Nh\u0169 t\u01b0\u01a1ng lipid d\u1ec5 b\u1ecb vi khu\u1ea9n, n\u1ea5m ph\u00e1t tri\u1ec3n; Candida albicans<\/em> ph\u00e1t tri\u1ec3n m\u1ea1nh h\u01a1n trong nh\u0169 t\u01b0\u01a1ng ch\u1ee9a d\u1ea7u rum.<\/li>\n<\/ul>\n

        T\u01b0\u01a1ng k\u1ef5<\/h2>\n

        T\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t oxy h\u00f3a m\u1ea1nh.<\/p>\n

        S\u1ea3n xu\u1ea5t<\/h2>\n

        \u00c9p v\u00e0\/ho\u1eb7c chi\u1ebft h\u1ea1t Carthamus tinctorius<\/em> L. (lo\u1ea1i I) ho\u1eb7c h\u1ea1t gi\u1ed1ng lai (lo\u1ea1i II \u2013 gi\u00e0u acid oleic), sau \u0111\u00f3 tinh ch\u1ebf; c\u00f3 th\u1ec3 th\u00eam ch\u1ea5t ch\u1ed1ng oxy h\u00f3a. Ph.Eur. y\u00eau c\u1ea7u nh\u00e3n ghi r\u00f5 lo\u1ea1i I hay II v\u00e0 c\u00f3 ph\u00f9 h\u1ee3p cho thu\u1ed1c ti\u00eam hay kh\u00f4ng.<\/p>\n

        An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
          \n
        • L\u00e0 d\u1ea7u \u0103n, nh\u00ecn chung kh\u00f4ng g\u00e2y nguy h\u1ea1i \u0111\u00e1ng k\u1ec3 khi d\u00ednh m\u1eaft, da, nu\u1ed1t ho\u1eb7c h\u00edt; c\u00f3 th\u1ec3 k\u00edch \u1ee9ng ho\u1eb7c d\u1ecb \u1ee9ng da, k\u00edch \u1ee9ng m\u1eaft. U\u1ed1ng li\u1ec1u l\u1edbn c\u00f3 th\u1ec3 g\u00e2y n\u00f4n, ti\u00eau ch\u1ea3y.<\/li>\n
        • LD50<\/sub> (chu\u1ed9t nh\u1eaft, ph\u00fac m\u1ea1c): tr\u00ean 50 g\/kg.<\/li>\n
        • \u0110un t\u1edbi ph\u00e2n h\u1ee7y sinh kh\u00f3i cay, k\u00edch \u1ee9ng.<\/li>\n<\/ul>\n

          T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
            \n
          • C\u00f3 trong FDA Inactive Ingredients Database (lotion b\u00f4i) v\u00e0 Canadian Natural Health Products Ingredients Database.<\/li>\n
          • C\u00f3 trong nh\u0169 t\u01b0\u01a1ng lipid t\u0129nh m\u1ea1ch l\u01b0u h\u00e0nh t\u1ea1i M\u1ef9, c\u00f4ng th\u1ee9c nang t\u1ea1i Canada v\u00e0 ch\u1ebf ph\u1ea9m dinh d\u01b0\u1ee1ng qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a t\u1ea1i Canada.<\/li>\n<\/ul>\n

            Ch\u1ea5t li\u00ean quan<\/h2>\n
              \n
            • D\u1ea7u h\u1ea1nh nh\u00e2n, d\u1ea7u canola, d\u1ea7u ng\u00f4, d\u1ea7u h\u1ea1t b\u00f4ng, d\u1ea7u l\u1ea1c, d\u1ea7u v\u1eebng, d\u1ea7u \u0111\u1eadu n\u00e0nh, d\u1ea7u h\u01b0\u1edbng d\u01b0\u01a1ng.<\/li>\n
            • Glycerid d\u1ea7u rum<\/strong> (monoglycerid d\u1ea7u rum; CAS 79982-97-1): ch\u1ea5t l\u00e0m m\u1ec1m, ch\u1ea5t nh\u0169 h\u00f3a trong m\u1ef9 ph\u1ea9m.<\/li>\n<\/ul>\n

              Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

              N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Safflower Oil<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

              \u1ea2nh minh h\u1ecda: thi\u1ebft k\u1ebf c\u1ee7a CPC1.<\/em><\/p>\n

              L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

              D\u1ea7u rum (d\u1ea7u h\u1ed3ng hoa) \u2013 t\u00e1 d\u01b0\u1ee3c d\u1ea7u cho thu\u1ed1c u\u1ed1ng, b\u00f4i, nh\u0169 t\u01b0\u01a1ng lipid ti\u00eam D\u1ea7u rum (d\u1ea7u h\u1ed3ng hoa, safflower oil) l\u00e0 d\u1ea7u b\u00e9o \u00e9p ho\u1eb7c chi\u1ebft t\u1eeb h\u1ea1t c\u00e2y rum (Carthamus tinctorius) r\u1ed3i tinh ch\u1ebf; ch\u1ea5t l\u1ecfng trong, s\u00e1nh, v\u00e0ng t\u1edbi v\u00e0ng nh\u1ea1t, m\u00f9i th\u1ef1c v\u1eadt nh\u1eb9. Trong b\u00e0o ch\u1ebf, d\u1ea7u […]<\/p>\n","protected":false},"author":1,"featured_media":3644,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3645","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dau-rum.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dau-rum-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dau-rum-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dau-rum-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dau-rum-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dau-rum.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dau-rum.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dau-rum-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"D\u1ea7u rum (d\u1ea7u h\u1ed3ng hoa) \u2013 t\u00e1 d\u01b0\u1ee3c d\u1ea7u cho thu\u1ed1c u\u1ed1ng, b\u00f4i, nh\u0169 t\u01b0\u01a1ng lipid ti\u00eam D\u1ea7u rum (d\u1ea7u h\u1ed3ng hoa, safflower oil) l\u00e0 d\u1ea7u b\u00e9o \u00e9p ho\u1eb7c chi\u1ebft t\u1eeb h\u1ea1t c\u00e2y rum (Carthamus tinctorius) r\u1ed3i tinh ch\u1ebf; ch\u1ea5t l\u1ecfng trong, s\u00e1nh, v\u00e0ng t\u1edbi v\u00e0ng nh\u1ea1t, m\u00f9i th\u1ef1c v\u1eadt nh\u1eb9. Trong b\u00e0o ch\u1ebf, d\u1ea7u…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3645","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3645"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3645\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3644"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3645"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3645"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3645"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}