{"id":3641,"date":"2026-09-29T09:25:19","date_gmt":"2026-09-29T02:25:19","guid":{"rendered":"https:\/\/cpc1.vn\/propylen-glycol-monolaurat\/"},"modified":"2026-09-29T12:12:42","modified_gmt":"2026-09-29T05:12:42","slug":"propylen-glycol-monolaurat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/propylen-glycol-monolaurat\/","title":{"rendered":"Propylen glycol monolaurat (Lauroglycol) \u2013 dung m\u00f4i lipid, t\u0103ng th\u1ea5m, \u0111\u1ed3ng nh\u0169 h\u00f3a"},"content":{"rendered":"

Propylen glycol monolaurat (Lauroglycol) \u2013 dung m\u00f4i lipid, t\u0103ng th\u1ea5m, \u0111\u1ed3ng nh\u0169 h\u00f3a<\/h1>\n

Propylen glycol monolaurat<\/strong> l\u00e0 h\u1ed7n h\u1ee3p mono- v\u00e0 diester c\u1ee7a propylen glycol v\u1edbi acid lauric, ch\u1ea5t l\u1ecfng d\u1ea7u kh\u00f4ng m\u00e0u ho\u1eb7c h\u01a1i v\u00e0ng \u1edf 20 \u00b0C. Trong b\u00e0o ch\u1ebf, \u0111\u00e2y l\u00e0 dung m\u00f4i cho ho\u1ea1t ch\u1ea5t th\u00e2n d\u1ea7u<\/strong>, t\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n cho nang, ch\u1ea5t t\u0103ng th\u1ea5m qua da<\/strong>, ch\u1ea5t \u0111\u1ed3ng nh\u0169 h\u00f3a<\/strong> trong vi nh\u0169 t\u01b0\u01a1ng v\u00e0 th\u00e0nh ph\u1ea7n h\u1ec7 t\u1ef1 nano nh\u0169 h\u00f3a (SNEDDS)<\/strong>.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nPropylen glycol monododecanoat, ester 2-hydroxypropyl c\u1ee7a acid lauric, E477; t\u00ean th\u01b0\u01a1ng m\u1ea1i Lauroglycol 90, Lauroglycol FCC, Capmul PG-12, Imwitor 412, Cithrol PGML<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n27194-74-7; 142-55-2<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC15<\/sub>H30<\/sub>O3<\/sub> \u2013 258,4<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t l\u00e0m m\u1ec1m, nh\u0169 h\u00f3a, di\u1ec7n ho\u1ea1t kh\u00f4ng ion, t\u00e1 d\u01b0\u1ee3c d\u1ea7u, t\u0103ng th\u1ea5m, t\u0103ng tan<\/td>\n<\/tr>\n
D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nBP, Ph.Eur., USP-NF (lo\u1ea1i I: 45\u201370% monoester, 30\u201355% diester; lo\u1ea1i II: \u2265 90% monoester, \u2264 10% diester)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • T\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n trong nang gelatin m\u1ec1m v\u00e0 c\u1ee9ng; dung m\u00f4i cho ho\u1ea1t ch\u1ea5t th\u00e2n d\u1ea7u.<\/li>\n
  • Ch\u1ea5t t\u0103ng th\u1ea5m trong h\u1ec7 cung c\u1ea5p thu\u1ed1c qua da.<\/li>\n
  • Ch\u1ea5t \u0111\u1ed3ng nh\u0169 h\u00f3a (nh\u0169 h\u00f3a th\u1ee9 c\u1ea5p) trong vi nh\u0169 t\u01b0\u01a1ng; th\u00e0nh ph\u1ea7n h\u1ec7 t\u1ef1 nano nh\u0169 h\u00f3a; \u0111\u1ed3ng dung m\u00f4i trong c\u00f4ng th\u1ee9c t\u1ef1 nh\u0169 h\u00f3a coenzym Q10.<\/li>\n
  • Ch\u1ea5t nh\u0169 h\u00f3a kh\u00f4ng \u0111\u1ed9c trong kem \u0111\u00e1nh r\u0103ng; ch\u1ea5t l\u00e0m m\u1ec1m, b\u00f4i tr\u01a1n trong lotion v\u00e0 son m\u00f4i (t\u0103ng kh\u1ea3 n\u0103ng ch\u1ed1ng \u0111\u00f4ng, gi\u1ea3m t\u1ea1o v\u1ea3y b\u1ec1 m\u1eb7t).<\/li>\n
  • T\u00e1 d\u01b0\u1ee3c lipid trong thu\u1ed1c th\u00fa y; c\u00f4ng th\u1ee9c thu\u1ed1c di\u1ec7t c\u1ecf, thu\u1ed1c tr\u1eeb s\u00e2u.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Ch\u1ea5t l\u1ecfng d\u1ea7u kh\u00f4ng m\u00e0u ho\u1eb7c h\u01a1i v\u00e0ng.<\/li>\n
    • D\u01b0\u1ee3c \u0111i\u1ec3n: ch\u1ec9 s\u1ed1 x\u00e0 ph\u00f2ng h\u00f3a 210\u2013245 (lo\u1ea1i I) ho\u1eb7c 200\u2013230 (lo\u1ea1i II); acid lauric \u2265 95,0% trong th\u00e0nh ph\u1ea7n acid b\u00e9o; propylen glycol t\u1ef1 do \u2264 5% (lo\u1ea1i I), \u2264 1% (lo\u1ea1i II).<\/li>\n
    • T\u1ef7 tr\u1ecdng 0,91\u20130,95 g\/cm\u00b3; chi\u1ebft su\u1ea5t 1,438; \u0111i\u1ec3m ch\u1ea3y kho\u1ea3ng 10\u201315 \u00b0C; HLB kho\u1ea3ng 3\u20135 t\u00f9y lo\u1ea1i.<\/li>\n
    • \u0110\u1ed9 tan: h\u1ea7u nh\u01b0 kh\u00f4ng tan trong n\u01b0\u1edbc; r\u1ea5t d\u1ec5 tan trong ethanol, aceton, n-hexan, methanol, methylen clorid; tan trong d\u1ea7u m\u1ee1.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      Ph\u00e2n h\u1ee7y r\u00f5 khi \u0111un n\u00f3ng c\u00f3 oxy. N\u1ebfu k\u1ebft tinh, l\u00e0m \u1ea5m 40\u201350 \u00b0C v\u00e0 \u0111\u1ed3ng nh\u1ea5t tr\u01b0\u1edbc khi d\u00f9ng. B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, tr\u00e1nh \u00e1nh s\u00e1ng v\u00e0 \u1ea9m.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t oxy h\u00f3a m\u1ea1nh.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Ester h\u00f3a propylen glycol v\u1edbi acid lauric.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
        \n
      • Nh\u00ecn chung \u0111\u01b0\u1ee3c coi l\u00e0 an to\u00e0n trong d\u01b0\u1ee3c ph\u1ea9m v\u00e0 m\u1ef9 ph\u1ea9m \u1edf m\u1ee9c d\u00f9ng hi\u1ec7n nay. Ti\u1ebfp x\u00fac da k\u00e9o d\u00e0i ho\u1eb7c l\u1eb7p l\u1ea1i c\u00f3 th\u1ec3 g\u00e2y d\u1ecb \u1ee9ng \u1edf ng\u01b0\u1eddi m\u1eabn c\u1ea3m; c\u00f3 th\u1ec3 k\u00edch \u1ee9ng m\u1eaft.<\/li>\n
      • D\u00f9ng n\u01a1i th\u00f4ng tho\u00e1ng; tr\u00e1nh d\u00ednh da, m\u1eaft; m\u1eb7c \u0111\u1ed3 b\u1ea3o h\u1ed9; tr\u00e1nh ngu\u1ed3n l\u1eeda. \u0110un t\u1edbi ph\u00e2n h\u1ee7y ho\u1eb7c ch\u00e1y kh\u00f4ng ho\u00e0n to\u00e0n sinh oxyd carbon.<\/li>\n<\/ul>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • C\u00f3 trong FDA Inactive Ingredients Database (vi\u00ean n\u00e9n u\u1ed1ng; m\u00e0ng qua da gi\u1ea3i ph\u00f3ng c\u00f3 ki\u1ec3m so\u00e1t); c\u00f3 trong thu\u1ed1c kh\u00f4ng d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam l\u01b0u h\u00e0nh t\u1ea1i Anh.<\/li>\n
        • \u0110\u01b0\u1ee3c ch\u1ea5p nh\u1eadn l\u00e0m ph\u1ee5 gia th\u1ef1c ph\u1ea9m t\u1ea1i ch\u00e2u \u00c2u; c\u00f3 trong Canadian Natural Health Products Ingredients Database.<\/li>\n
        • C\u00f3 chuy\u00ean lu\u1eadn trong BP, Ph.Eur., USP-NF.<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan<\/h2>\n

          Propylen glycol dilaurat; xem th\u00eam glyceryl laurat, polyoxylglycerid.<\/p>\n

          Ghi ch\u00fa:<\/strong> s\u1ed1 EINECS 248-315-4 v\u00e0 205-542-3; PubChem CID 14870.<\/p>\n

          Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

          N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Propylene Glycol Monolaurate<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

          \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

          L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          Propylen glycol monolaurat (Lauroglycol) \u2013 dung m\u00f4i lipid, t\u0103ng th\u1ea5m, \u0111\u1ed3ng nh\u0169 h\u00f3a Propylen glycol monolaurat l\u00e0 h\u1ed7n h\u1ee3p mono- v\u00e0 diester c\u1ee7a propylen glycol v\u1edbi acid lauric, ch\u1ea5t l\u1ecfng d\u1ea7u kh\u00f4ng m\u00e0u ho\u1eb7c h\u01a1i v\u00e0ng \u1edf 20 \u00b0C. Trong b\u00e0o ch\u1ebf, \u0111\u00e2y l\u00e0 dung m\u00f4i cho ho\u1ea1t ch\u1ea5t th\u00e2n d\u1ea7u, t\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n cho […]<\/p>\n","protected":false},"author":1,"featured_media":3640,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3641","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/propylen-glycol-monolaurat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/propylen-glycol-monolaurat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/propylen-glycol-monolaurat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/propylen-glycol-monolaurat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/propylen-glycol-monolaurat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/propylen-glycol-monolaurat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/propylen-glycol-monolaurat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/propylen-glycol-monolaurat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Propylen glycol monolaurat (Lauroglycol) \u2013 dung m\u00f4i lipid, t\u0103ng th\u1ea5m, \u0111\u1ed3ng nh\u0169 h\u00f3a Propylen glycol monolaurat l\u00e0 h\u1ed7n h\u1ee3p mono- v\u00e0 diester c\u1ee7a propylen glycol v\u1edbi acid lauric, ch\u1ea5t l\u1ecfng d\u1ea7u kh\u00f4ng m\u00e0u ho\u1eb7c h\u01a1i v\u00e0ng \u1edf 20 \u00b0C. Trong b\u00e0o ch\u1ebf, \u0111\u00e2y l\u00e0 dung m\u00f4i cho ho\u1ea1t ch\u1ea5t th\u00e2n d\u1ea7u, t\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n cho…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3641","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3641"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3641\/revisions"}],"predecessor-version":[{"id":3939,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3641\/revisions\/3939"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3640"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3641"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3641"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3641"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}