{"id":3605,"date":"2026-09-29T09:16:37","date_gmt":"2026-09-29T02:16:37","guid":{"rendered":"https:\/\/cpc1.vn\/alcol-myristylic\/"},"modified":"2026-09-29T11:52:52","modified_gmt":"2026-09-29T04:52:52","slug":"alcol-myristylic","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/alcol-myristylic\/","title":{"rendered":"Alcol myristylic (1-tetradecanol) \u2013 ch\u1ea5t l\u00e0m m\u1ec1m, \u1ed5n \u0111\u1ecbnh nh\u0169 t\u01b0\u01a1ng, t\u0103ng th\u1ea5m"},"content":{"rendered":"

Alcol myristylic (1-tetradecanol) \u2013 ch\u1ea5t l\u00e0m m\u1ec1m, \u1ed5n \u0111\u1ecbnh nh\u0169 t\u01b0\u01a1ng, t\u0103ng th\u1ea5m<\/h1>\n

Alcol myristylic<\/strong> (1-tetradecanol, myristyl alcohol) l\u00e0 alcol b\u00e9o no m\u1ea1ch th\u1eb3ng 14 carbon, ch\u1ea5t r\u1eafn k\u1ebft tinh tr\u1eafng, m\u00f9i s\u00e1p. Trong b\u00e0o ch\u1ebf, alcol myristylic l\u00e0 ch\u1ea5t l\u00e0m m\u1ec1m<\/strong>, \u1ed5n \u0111\u1ecbnh nh\u0169 t\u01b0\u01a1ng<\/strong>, di\u1ec7n ho\u1ea1t kh\u00f4ng ion<\/strong>, t\u00e1 d\u01b0\u1ee3c d\u1ea7u<\/strong> v\u00e0 t\u0103ng \u0111\u1ed9 nh\u1edbt<\/strong>; \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u l\u00e0m ch\u1ea5t t\u0103ng th\u1ea5m qua da<\/strong>.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nMyristyl alcohol, 1-tetradecanol, tetradecyl alcohol, alcol myristic<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n112-72-1<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC14<\/sub>H30<\/sub>O \u2013 214,4<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t l\u00e0m m\u1ec1m, \u1ed5n \u0111\u1ecbnh nh\u0169 t\u01b0\u01a1ng, di\u1ec7n ho\u1ea1t kh\u00f4ng ion, t\u00e1 d\u01b0\u1ee3c d\u1ea7u, t\u0103ng \u0111\u1ed9 nh\u1edbt<\/td>\n<\/tr>\n
D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nUSP-NF<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • D\u00f9ng trong ch\u1ebf ph\u1ea9m u\u1ed1ng, ti\u00eam v\u00e0 b\u00f4i ngo\u00e0i (kem, lotion, h\u1ed7n d\u1ecbch b\u00f4i; vi\u00ean gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i).<\/li>\n
  • Ch\u1ea5t t\u0103ng th\u1ea5m: \u0111\u00e3 \u0111\u00e1nh gi\u00e1 trong mi\u1ebfng d\u00e1n melatonin qua da; nghi\u00ean c\u1ee9u trong vi nh\u0169 t\u01b0\u01a1ng d\u1eabn thu\u1ed1c qua da.<\/li>\n
  • H\u1ec7 ti\u1ec3u ph\u00e2n lipid gi\u1ea3i ph\u00f3ng c\u00f3 ki\u1ec3m so\u00e1t. Ch\u1ea5t \u1ed5n \u0111\u1ecbnh l\u1edbp k\u00e9p trong niosome (ketorolac tromethamin, zidovudin) \u2013 cho t\u1ed1c \u0111\u1ed9 gi\u1ea3i ph\u00f3ng ch\u1eadm h\u01a1n r\u00f5 so v\u1edbi niosome d\u00f9ng cholesterol.<\/li>\n
  • Ch\u1ea5t t\u1ea1o h\u01b0\u01a1ng trong th\u1ef1c ph\u1ea9m; m\u1ef9 ph\u1ea9m \u1edf n\u1ed3ng \u0111\u1ed9 d\u01b0\u1edbi 0,01% t\u1edbi 5%.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Ch\u1ea5t r\u1eafn k\u1ebft tinh tr\u1eafng, m\u00f9i s\u00e1p; k\u1ebft tinh t\u1eeb ethanol cho d\u1ea1ng v\u1ea3y ho\u1eb7c tinh th\u1ec3 \u0111\u1ee5c.<\/li>\n
    • \u0110i\u1ec3m ch\u1ea3y kho\u1ea3ng 38 \u00b0C; t\u1ef7 tr\u1ecdng 0,8355 g\/cm\u00b3 (r\u1eafn, 20 \u00b0C), 0,8236 g\/cm\u00b3 (l\u1ecfng, 38 \u00b0C); \u0111i\u1ec3m ch\u1edbp ch\u00e1y 140 \u00b0C (c\u1ed1c h\u1edf).<\/li>\n
    • USP-NF: ch\u1ec9 s\u1ed1 hydroxyl 250\u2013267; h\u00e0m l\u01b0\u1ee3ng 90,0\u2013102,0%.<\/li>\n
    • \u0110\u1ed9 tan: h\u1ea7u nh\u01b0 kh\u00f4ng tan trong n\u01b0\u1edbc; tan trong ether; h\u01a1i tan trong ethanol 95%.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      Ch\u00e1y \u0111\u01b0\u1ee3c khi g\u1eb7p nhi\u1ec7t ho\u1eb7c l\u1eeda; c\u00f3 th\u1ec3 ph\u1ea3n \u1ee9ng v\u1edbi ch\u1ea5t oxy h\u00f3a. \u0110un t\u1edbi ph\u00e2n h\u1ee7y sinh kh\u00f3i cay, k\u00edch \u1ee9ng.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      C\u00f3 trong s\u00e1p v\u00e0 d\u1ea7u c\u00e1 nh\u00e0 t\u00e1ng; t\u1ed5ng h\u1ee3p b\u1eb1ng kh\u1eed ester acid b\u00e9o b\u1eb1ng natri ho\u1eb7c kh\u1eed acid b\u00e9o b\u1eb1ng lithi nh\u00f4m hydrid.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
        \n
      • D\u1ea1ng tinh khi\u1ebft \u0111\u1ed9c nh\u1eb9 khi nu\u1ed1t; c\u00f3 d\u1eef li\u1ec7u th\u1ef1c nghi\u1ec7m g\u00e2y kh\u1ed1i u. G\u00e2y k\u00edch \u1ee9ng da ng\u01b0\u1eddi: b\u00f4i 75 mg ng\u1eaft qu\u00e3ng 3 l\u1ea7n trong 72 gi\u1edd g\u00e2y ban \u0111\u1ecf v\u1eeba \u2013 n\u1eb7ng v\u00e0 ph\u00f9 v\u1eeba.<\/li>\n
      • Trong c\u00e1c alcol b\u00e9o no, alcol myristylic t\u0103ng th\u1ea5m k\u00e9m h\u01a1n decanol, undecanol, alcol laurylic nh\u01b0ng k\u00edch \u1ee9ng da nhi\u1ec1u h\u01a1n. Th\u1eed \u00e1p da n\u00ean d\u00f9ng n\u1ed3ng \u0111\u1ed9 5% trong vaselin (10% g\u00e2y k\u00edch \u1ee9ng); c\u00f3 b\u00e1o c\u00e1o d\u1ecb \u1ee9ng ti\u1ebfp x\u00fac.<\/li>\n
      • H\u1ed9i \u0111\u1ed3ng CIR k\u1ebft lu\u1eadn an to\u00e0n trong m\u1ef9 ph\u1ea9m \u1edf m\u1ee9c d\u00f9ng hi\u1ec7n nay.<\/li>\n
      • LD50<\/sub> (th\u1ecf, qua da): tr\u00ean 5 g\/kg; (chu\u1ed9t c\u1ed1ng, u\u1ed1ng): 5 g\/kg.<\/li>\n
      • N\u00ean \u0111eo g\u0103ng khi thao t\u00e1c.<\/li>\n<\/ul>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • C\u00f3 trong FDA Inactive Ingredients Database (vi\u00ean u\u1ed1ng gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i; kem, lotion, h\u1ed7n d\u1ecbch b\u00f4i); c\u00f3 trong kem l\u01b0u h\u00e0nh t\u1ea1i Anh.<\/li>\n
        • C\u00f3 chuy\u00ean lu\u1eadn trong USP-NF; c\u00f3 ti\u00eau chu\u1ea9n trong Food Chemicals Codex.<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan<\/h2>\n

          Acid lauric, acid myristic, acid palmitic, kali myristat, natri myristat, acid stearic; xem th\u00eam alcol cetylic, alcol stearylic.<\/p>\n

          Ghi ch\u00fa:<\/strong> s\u1ed1 EINECS 204-000-3; PubChem CID 8209.<\/p>\n

          Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

          N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Myristyl Alcohol<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

          \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

          L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          Alcol myristylic (1-tetradecanol) \u2013 ch\u1ea5t l\u00e0m m\u1ec1m, \u1ed5n \u0111\u1ecbnh nh\u0169 t\u01b0\u01a1ng, t\u0103ng th\u1ea5m Alcol myristylic (1-tetradecanol, myristyl alcohol) l\u00e0 alcol b\u00e9o no m\u1ea1ch th\u1eb3ng 14 carbon, ch\u1ea5t r\u1eafn k\u1ebft tinh tr\u1eafng, m\u00f9i s\u00e1p. Trong b\u00e0o ch\u1ebf, alcol myristylic l\u00e0 ch\u1ea5t l\u00e0m m\u1ec1m, \u1ed5n \u0111\u1ecbnh nh\u0169 t\u01b0\u01a1ng, di\u1ec7n ho\u1ea1t kh\u00f4ng ion, t\u00e1 d\u01b0\u1ee3c d\u1ea7u v\u00e0 t\u0103ng […]<\/p>\n","protected":false},"author":1,"featured_media":3604,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3605","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-myristylic.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-myristylic-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-myristylic-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-myristylic-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-myristylic-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-myristylic.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-myristylic.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-myristylic-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Alcol myristylic (1-tetradecanol) \u2013 ch\u1ea5t l\u00e0m m\u1ec1m, \u1ed5n \u0111\u1ecbnh nh\u0169 t\u01b0\u01a1ng, t\u0103ng th\u1ea5m Alcol myristylic (1-tetradecanol, myristyl alcohol) l\u00e0 alcol b\u00e9o no m\u1ea1ch th\u1eb3ng 14 carbon, ch\u1ea5t r\u1eafn k\u1ebft tinh tr\u1eafng, m\u00f9i s\u00e1p. Trong b\u00e0o ch\u1ebf, alcol myristylic l\u00e0 ch\u1ea5t l\u00e0m m\u1ec1m, \u1ed5n \u0111\u1ecbnh nh\u0169 t\u01b0\u01a1ng, di\u1ec7n ho\u1ea1t kh\u00f4ng ion, t\u00e1 d\u01b0\u1ee3c d\u1ea7u v\u00e0 t\u0103ng…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3605","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3605"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3605\/revisions"}],"predecessor-version":[{"id":3730,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3605\/revisions\/3730"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3604"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3605"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3605"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3605"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}