{"id":3601,"date":"2026-09-29T09:14:04","date_gmt":"2026-09-29T02:14:04","guid":{"rendered":"https:\/\/cpc1.vn\/mannitol-va-sorbitol-dong-xu-ly\/"},"modified":"2026-09-29T09:14:04","modified_gmt":"2026-09-29T02:14:04","slug":"mannitol-va-sorbitol-dong-xu-ly","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/mannitol-va-sorbitol-dong-xu-ly\/","title":{"rendered":"Mannitol \u2013 sorbitol \u0111\u1ed3ng x\u1eed l\u00fd (Compressol SM) \u2013 t\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng, vi\u00ean nhai"},"content":{"rendered":"

Mannitol \u2013 sorbitol \u0111\u1ed3ng x\u1eed l\u00fd (Compressol SM) \u2013 t\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng, vi\u00ean nhai<\/h1>\n

Mannitol \u2013 sorbitol \u0111\u1ed3ng x\u1eed l\u00fd<\/strong> (t\u00ean th\u01b0\u01a1ng m\u1ea1i Compressol S, Compressol SM) l\u00e0 h\u1ed7n h\u1ee3p \u0111\u1ed3ng x\u1eed l\u00fd c\u1ee7a hai polyol mannitol v\u00e0 sorbitol, d\u1ea1ng b\u1ed9t m\u1ecbn tr\u1eafng, c\u1ea3m gi\u00e1c m\u1ecbn trong mi\u1ec7ng. \u0110\u00e2y l\u00e0 t\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng<\/strong> tr\u01a1n ch\u1ea3y v\u00e0 ch\u1ecbu n\u00e9n t\u1ed1t, \u0111\u1eb7c bi\u1ec7t ph\u00f9 h\u1ee3p vi\u00ean nhai<\/strong> v\u00e0 d\u01b0\u1ee3c ch\u1ea5t nh\u1ea1y \u1ea9m<\/strong>.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean th\u01b0\u01a1ng m\u1ea1i<\/td>\nCompressol S, Compressol SM<\/td>\n<\/tr>\n
Th\u00e0nh ph\u1ea7n<\/td>\nMannitol v\u00e0 sorbitol, \u0111\u1ed3ng x\u1eed l\u00fd b\u1eb1ng quy tr\u00ecnh \u0111\u1ed9c quy\u1ec1n<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nT\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng<\/td>\n<\/tr>\n
D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nKh\u00f4ng c\u00f3 chuy\u00ean lu\u1eadn cho h\u1ed7n h\u1ee3p; mannitol v\u00e0 sorbitol c\u00f3 chuy\u00ean lu\u1eadn ri\u00eang trong BP, JP, Ph.Eur., USP-NF<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • D\u1eadp th\u1eb3ng vi\u00ean h\u00e0m l\u01b0\u1ee3ng ho\u1ea1t ch\u1ea5t cao v\u00e0\/ho\u1eb7c ho\u1ea1t ch\u1ea5t kh\u00f3 n\u00e9n, nh\u1edd tr\u01a1n ch\u1ea3y v\u00e0 ch\u1ecbu n\u00e9n t\u1ed1t.<\/li>\n
  • \u00cdt h\u00fat \u1ea9m h\u01a1n sorbitol th\u01b0\u1eddng, n\u00ean d\u00f9ng \u0111\u01b0\u1ee3c cho ho\u1ea1t ch\u1ea5t nh\u1ea1y \u1ea9m.<\/li>\n
  • V\u1ecb d\u1ec5 ch\u1ecbu, c\u1ea3m gi\u00e1c mi\u1ec7ng t\u1ed1t \u2013 \u0111\u1eb7c bi\u1ec7t ph\u00f9 h\u1ee3p vi\u00ean nhai.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • B\u1ed9t m\u1ecbn tr\u1eafng t\u1edbi tr\u1eafng ng\u00e0, m\u1ecbn trong mi\u1ec7ng; tan trong n\u01b0\u1edbc.<\/li>\n
    • Compressol SM: kh\u1ed1i l\u01b0\u1ee3ng ri\u00eang sau g\u00f5 0,5\u20130,65 g\/cm\u00b3; d\u01b0\u1edbi 10% c\u00f2n tr\u00ean r\u00e2y 60 mesh, d\u01b0\u1edbi 18% qua r\u00e2y 325 mesh; t\u1ed5ng polyol 96\u2013101%.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      Tr\u00e1nh nhi\u1ec7t \u0111\u1ed9 v\u00e0 \u0111\u1ed9 \u1ea9m cao; b\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      Nh\u01b0 mannitol v\u00e0 sorbitol; c\u00f3 th\u1ec3 ph\u1ea3n \u1ee9ng v\u1edbi acid m\u1ea1nh ho\u1eb7c ch\u1ea5t oxy h\u00f3a. Khi ph\u00e2n h\u1ee7y sinh CO, CO2<\/sub> v\u00e0\/ho\u1eb7c hydrocarbon ph\u00e2n t\u1eed l\u01b0\u1ee3ng th\u1ea5p.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Quy tr\u00ecnh \u0111\u1ed3ng x\u1eed l\u00fd \u0111\u1ed9c quy\u1ec1n c\u1ee7a nh\u00e0 s\u1ea3n xu\u1ea5t.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
        \n
      • B\u1ed9t tr\u1eafng kh\u00f4ng ch\u00e1y. D\u00ednh m\u1eaft c\u00f3 th\u1ec3 k\u00edch \u1ee9ng nh\u1eb9; ti\u1ebfp x\u00fac da ng\u1eafn kh\u00f4ng k\u00edch \u1ee9ng, k\u00e9o d\u00e0i ho\u1eb7c l\u1eb7p l\u1ea1i c\u00f3 th\u1ec3 k\u00edch \u1ee9ng. Nu\u1ed1t l\u01b0\u1ee3ng l\u1edbn c\u00f3 th\u1ec3 g\u00e2y r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a, k\u1ec3 c\u1ea3 t\u00e1c d\u1ee5ng nhu\u1eadn tr\u00e0ng; b\u1ee5i qu\u00e1 m\u1ee9c c\u00f3 th\u1ec3 k\u00edch \u1ee9ng h\u00f4 h\u1ea5p.<\/li>\n
      • B\u1ee5i t\u00edch t\u1ee5 trong kh\u00f4ng kh\u00ed c\u00f3 nguy c\u01a1 n\u1ed5 khi c\u00f3 ngu\u1ed3n l\u1eeda. Tr\u00e1nh h\u00edt b\u1ee5i, tr\u00e1nh d\u00ednh m\u1eaft, r\u1eeda k\u1ef9 sau thao t\u00e1c.<\/li>\n<\/ul>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • C\u1ea3 hai th\u00e0nh ph\u1ea7n \u0111\u1ec1u GRAS v\u00e0 \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn l\u00e0m ph\u1ee5 gia th\u1ef1c ph\u1ea9m t\u1ea1i ch\u00e2u \u00c2u.<\/li>\n
        • Mannitol: c\u00f3 trong FDA IID (ti\u00eam ph\u00fac m\u1ea1c, b\u1eafp, t\u0129nh m\u1ea1ch, d\u01b0\u1edbi da; d\u1ecbch truy\u1ec1n; vi\u00ean ng\u1eadm m\u00e1, vi\u00ean, b\u1ed9t, nang u\u1ed1ng v\u00e0 d\u01b0\u1edbi l\u01b0\u1ee1i; nh\u00e3n khoa; dung d\u1ecbch b\u00f4i).<\/li>\n
        • Sorbitol: c\u00f3 trong FDA IID (ti\u00eam kh\u1edbp, ti\u00eam b\u1eafp; m\u0169i; nang, dung d\u1ecbch, h\u1ed7n d\u1ecbch, siro, vi\u00ean u\u1ed1ng; tr\u1ef1c tr\u00e0ng, b\u00f4i, \u00e2m \u0111\u1ea1o).<\/li>\n
        • C\u1ea3 hai c\u00f3 trong thu\u1ed1c l\u01b0u h\u00e0nh t\u1ea1i Anh v\u00e0 Canadian Natural Health Products Ingredients Database.<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan<\/h2>\n

          Mannitol, sorbitol.<\/p>\n

          Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

          N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Mannitol and Sorbitol, Coprocessed<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

          \u1ea2nh minh h\u1ecda: thi\u1ebft k\u1ebf c\u1ee7a CPC1.<\/em><\/p>\n

          L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          Mannitol \u2013 sorbitol \u0111\u1ed3ng x\u1eed l\u00fd (Compressol SM) \u2013 t\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng, vi\u00ean nhai Mannitol \u2013 sorbitol \u0111\u1ed3ng x\u1eed l\u00fd (t\u00ean th\u01b0\u01a1ng m\u1ea1i Compressol S, Compressol SM) l\u00e0 h\u1ed7n h\u1ee3p \u0111\u1ed3ng x\u1eed l\u00fd c\u1ee7a hai polyol mannitol v\u00e0 sorbitol, d\u1ea1ng b\u1ed9t m\u1ecbn tr\u1eafng, c\u1ea3m gi\u00e1c m\u1ecbn trong mi\u1ec7ng. \u0110\u00e2y l\u00e0 t\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng […]<\/p>\n","protected":false},"author":1,"featured_media":3600,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3601","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mannitol-va-sorbitol-dong-xu-ly.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mannitol-va-sorbitol-dong-xu-ly-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mannitol-va-sorbitol-dong-xu-ly-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mannitol-va-sorbitol-dong-xu-ly-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mannitol-va-sorbitol-dong-xu-ly-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mannitol-va-sorbitol-dong-xu-ly.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mannitol-va-sorbitol-dong-xu-ly.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mannitol-va-sorbitol-dong-xu-ly-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Mannitol \u2013 sorbitol \u0111\u1ed3ng x\u1eed l\u00fd (Compressol SM) \u2013 t\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng, vi\u00ean nhai Mannitol \u2013 sorbitol \u0111\u1ed3ng x\u1eed l\u00fd (t\u00ean th\u01b0\u01a1ng m\u1ea1i Compressol S, Compressol SM) l\u00e0 h\u1ed7n h\u1ee3p \u0111\u1ed3ng x\u1eed l\u00fd c\u1ee7a hai polyol mannitol v\u00e0 sorbitol, d\u1ea1ng b\u1ed9t m\u1ecbn tr\u1eafng, c\u1ea3m gi\u00e1c m\u1ecbn trong mi\u1ec7ng. \u0110\u00e2y l\u00e0 t\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3601","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3601"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3601\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3600"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3601"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3601"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3601"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}