{"id":3597,"date":"2026-09-29T09:13:49","date_gmt":"2026-09-29T02:13:49","guid":{"rendered":"https:\/\/cpc1.vn\/d-mannose\/"},"modified":"2026-09-29T09:13:49","modified_gmt":"2026-09-29T02:13:49","slug":"d-mannose","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/d-mannose\/","title":{"rendered":"D-Mannose \u2013 ch\u1ea5t t\u1ea1o ng\u1ecdt, ch\u1ea5t ch\u1ed1ng oxy h\u00f3a"},"content":{"rendered":"

D-Mannose \u2013 ch\u1ea5t t\u1ea1o ng\u1ecdt, ch\u1ea5t ch\u1ed1ng oxy h\u00f3a<\/h1>\n

D-Mannose<\/strong> l\u00e0 monosaccharid 6 carbon, \u0111\u1ed3ng ph\u00e2n C2 c\u1ee7a glucose, d\u1ea1ng b\u1ed9t k\u1ebft tinh kh\u00f4ng m\u00e0u ho\u1eb7c tr\u1eafng, v\u1ecb ng\u1ecdt k\u00e8m h\u1eadu v\u1ecb \u0111\u1eafng. Trong b\u00e0o ch\u1ebf, D-mannose l\u00e0 ch\u1ea5t t\u1ea1o ng\u1ecdt<\/strong> cho thu\u1ed1c u\u1ed1ng; lo\u1ea1i d\u1eadp th\u1eb3ng \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m ch\u1ea5t ch\u1ed1ng oxy h\u00f3a<\/strong> trong s\u1ea3n ph\u1ea9m dinh d\u01b0\u1ee1ng.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nD-Mannopyranose, carubinose, seminose<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n3458-28-4<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC6<\/sub>H12<\/sub>O6<\/sub> \u2013 180,16<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t ch\u1ed1ng oxy h\u00f3a, ch\u1ea5t t\u1ea1o ng\u1ecdt<\/td>\n<\/tr>\n
D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nKh\u00f4ng c\u00f3 chuy\u00ean lu\u1eadn; c\u00f3 trong BP d\u01b0\u1edbi d\u1ea1ng thu\u1ed1c th\u1eed<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • Ch\u1ea5t t\u1ea1o ng\u1ecdt trong thu\u1ed1c u\u1ed1ng.<\/li>\n
  • Lo\u1ea1i d\u1eadp th\u1eb3ng (v\u00ed d\u1ee5 MannoTab) d\u00f9ng l\u00e0m ch\u1ea5t ch\u1ed1ng oxy h\u00f3a trong s\u1ea3n ph\u1ea9m dinh d\u01b0\u1ee1ng.<\/li>\n
  • Nghi\u00ean c\u1ee9u: ch\u1ea5t bi\u1ebfn \u0111\u1ed5i b\u1ec1 m\u1eb7t ti\u1ec3u ph\u00e2n nano v\u00e0 liposome \u0111\u1ec3 h\u01b0\u1edbng \u0111\u00edch \u0111\u1ea1i th\u1ef1c b\u00e0o, t\u0103ng hi\u1ec7u qu\u1ea3 \u0111\u01b0\u1eddng u\u1ed1ng v\u00e0 ph\u1ebf nang; ch\u1ed1ng k\u1ebft t\u1ee5 trong h\u1ed7n d\u1ecbch \u0111\u00f4ng kh\u00f4.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • B\u1ed9t k\u1ebft tinh kh\u00f4ng m\u00e0u ho\u1eb7c tr\u1eafng, ng\u1ecdt v\u1edbi h\u1eadu v\u1ecb \u0111\u1eafng \u2013 s\u1ef1 kh\u00e1c bi\u1ec7t v\u1ecb gi\u00e1c \u0111\u01b0\u1ee3c cho l\u00e0 do d\u1ea1ng \u03b1 v\u00e0 \u03b2 c\u00f3 v\u1ecb kh\u00e1c nhau.<\/li>\n
    • T\u1ef7 tr\u1ecdng 1,54 g\/cm\u00b3; pKa 11,98; n\u00f3ng ch\u1ea3y 132\u2013140 \u00b0C (ph\u00e2n h\u1ee7y), d\u1ea1ng \u03b1 133 \u00b0C.<\/li>\n
    • N\u0103ng su\u1ea5t quay c\u1ef1c +13,7\u00b0 t\u1edbi +14,2\u00b0 (dung d\u1ecbch 20% trong n\u01b0\u1edbc c\u00f3 kho\u1ea3ng 0,05% NH3<\/sub>).<\/li>\n<\/ul>\n\n\n\n\n\n\n\n\n
      Dung m\u00f4i<\/th>\n\u0110\u1ed9 tan \u1edf 20 \u00b0C<\/th>\n<\/tr>\n<\/thead>\n
      N\u01b0\u1edbc<\/td>\n1 trong 0,4<\/td>\n<\/tr>\n
      Pyridin<\/td>\n1 trong 3,5<\/td>\n<\/tr>\n
      Methanol<\/td>\n1 trong 120<\/td>\n<\/tr>\n
      Ethanol<\/td>\n1 trong 250<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ec1n \u1edf tr\u1ea1ng th\u00e1i kh\u00f4 v\u00e0 trong dung d\u1ecbch n\u01b0\u1edbc; n\u1ea5m men c\u00f3 th\u1ec3 l\u00ean men \u0111\u01b0\u1ee3c. B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u00e0i li\u1ec7u g\u1ed1c kh\u00f4ng ghi nh\u1eadn t\u01b0\u01a1ng k\u1ef5 c\u1ee5 th\u1ec3.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      T\u1eeb glucose qua chuy\u1ec3n h\u00f3a Lobry de Bruyn \u2013 van Ekenstein; ho\u1eb7c oxy h\u00f3a mannitol; ho\u1eb7c t\u00e1ch t\u1eeb d\u1ecbch th\u1ee7y ph\u00e2n g\u1ed7, sinh kh\u1ed1i b\u1eb1ng s\u1eafc k\u00fd trong m\u00f4i tr\u01b0\u1eddng n\u01b0\u1edbc.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
        \n
      • D\u00f9ng trong ch\u1ebf ph\u1ea9m u\u1ed1ng. Ph\u1ea7n l\u1edbn D-mannose u\u1ed1ng v\u00e0o \u0111\u01b0\u1ee3c th\u1ea3i nguy\u00ean d\u1ea1ng qua n\u01b0\u1edbc ti\u1ec3u trong 30\u201360 ph\u00fat, kh\u00f4ng l\u00e0m t\u0103ng \u0111\u00e1ng k\u1ec3 \u0111\u01b0\u1eddng huy\u1ebft.<\/li>\n
      • Thao t\u00e1c theo l\u01b0u \u00fd th\u00f4ng th\u01b0\u1eddng.<\/li>\n<\/ul>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • C\u00f3 trong FDA Inactive Ingredients Database (vi\u00ean n\u00e9n u\u1ed1ng) v\u00e0 Canadian Natural Health Products Ingredients Database.<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan<\/h2>\n

          Dextrose, mannitol.<\/p>\n

          Ghi ch\u00fa:<\/strong> s\u1ed1 EINECS 222-392-4; PubChem CID 18950.<\/p>\n

          Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

          N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn D-Mannose<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

          \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

          L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          D-Mannose \u2013 ch\u1ea5t t\u1ea1o ng\u1ecdt, ch\u1ea5t ch\u1ed1ng oxy h\u00f3a D-Mannose l\u00e0 monosaccharid 6 carbon, \u0111\u1ed3ng ph\u00e2n C2 c\u1ee7a glucose, d\u1ea1ng b\u1ed9t k\u1ebft tinh kh\u00f4ng m\u00e0u ho\u1eb7c tr\u1eafng, v\u1ecb ng\u1ecdt k\u00e8m h\u1eadu v\u1ecb \u0111\u1eafng. Trong b\u00e0o ch\u1ebf, D-mannose l\u00e0 ch\u1ea5t t\u1ea1o ng\u1ecdt cho thu\u1ed1c u\u1ed1ng; lo\u1ea1i d\u1eadp th\u1eb3ng \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m ch\u1ea5t ch\u1ed1ng oxy h\u00f3a trong […]<\/p>\n","protected":false},"author":1,"featured_media":3596,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3597","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/d-mannose.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/d-mannose-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/d-mannose-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/d-mannose-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/d-mannose-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/d-mannose.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/d-mannose.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/d-mannose-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"D-Mannose \u2013 ch\u1ea5t t\u1ea1o ng\u1ecdt, ch\u1ea5t ch\u1ed1ng oxy h\u00f3a D-Mannose l\u00e0 monosaccharid 6 carbon, \u0111\u1ed3ng ph\u00e2n C2 c\u1ee7a glucose, d\u1ea1ng b\u1ed9t k\u1ebft tinh kh\u00f4ng m\u00e0u ho\u1eb7c tr\u1eafng, v\u1ecb ng\u1ecdt k\u00e8m h\u1eadu v\u1ecb \u0111\u1eafng. Trong b\u00e0o ch\u1ebf, D-mannose l\u00e0 ch\u1ea5t t\u1ea1o ng\u1ecdt cho thu\u1ed1c u\u1ed1ng; lo\u1ea1i d\u1eadp th\u1eb3ng \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m ch\u1ea5t ch\u1ed1ng oxy h\u00f3a trong…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3597","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3597"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3597\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3596"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3597"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3597"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3597"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}