{"id":3587,"date":"2026-09-29T09:11:05","date_gmt":"2026-09-29T02:11:05","guid":{"rendered":"https:\/\/cpc1.vn\/lactose-monohydrat-va-cellulose-bot-dong-xu-ly\/"},"modified":"2026-09-29T12:05:09","modified_gmt":"2026-09-29T05:05:09","slug":"lactose-monohydrat-va-cellulose-bot-dong-xu-ly","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/lactose-monohydrat-va-cellulose-bot-dong-xu-ly\/","title":{"rendered":"Lactose monohydrat \u2013 cellulose b\u1ed9t \u0111\u1ed3ng x\u1eed l\u00fd (Cellactose 80) \u2013 t\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Lactose monohydrat \u2013 cellulose b\u1ed9t \u0111\u1ed3ng x\u1eed l\u00fd (Cellactose 80) \u2013 t\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng<\/h1>\n<p><strong>Lactose monohydrat \u2013 cellulose b\u1ed9t \u0111\u1ed3ng x\u1eed l\u00fd<\/strong> (t\u00ean th\u01b0\u01a1ng m\u1ea1i Cellactose 80) l\u00e0 ti\u1ec3u ph\u00e2n t\u00edch h\u1ee3p g\u1ed3m kho\u1ea3ng 75% lactose monohydrat v\u00e0 25% cellulose b\u1ed9t, t\u1ea1o b\u1eb1ng \u0111\u1ed3ng s\u1ea5y phun. S\u1ea3n ph\u1ea9m l\u00e0 <strong>t\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng<\/strong> v\u00e0 <strong>t\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n<\/strong>, gi\u00fap t\u0103ng kh\u1ea3 n\u0103ng ch\u1ecbu n\u00e9n v\u00e0 c\u1ea3i thi\u1ec7n c\u1ea3m gi\u00e1c trong mi\u1ec7ng.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean th\u01b0\u01a1ng m\u1ea1i<\/td>\n<td>Cellactose 80<\/td>\n<\/tr>\n<tr>\n<td>Th\u00e0nh ph\u1ea7n<\/td>\n<td>73\u201377% lactose monohydrat v\u00e0 23\u201327% cellulose b\u1ed9t trong c\u00f9ng m\u1ed9t ti\u1ec3u ph\u00e2n<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\n<td>T\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n vi\u00ean n\u00e9n\/vi\u00ean nang<\/td>\n<\/tr>\n<tr>\n<td>D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\n<td>Kh\u00f4ng c\u00f3 chuy\u00ean lu\u1eadn cho h\u1ed7n h\u1ee3p; lactose monohydrat v\u00e0 cellulose b\u1ed9t c\u00f3 chuy\u00ean lu\u1eadn ri\u00eang (\u0111\u00e3 h\u00e0i h\u00f2a nhi\u1ec1u ch\u1ec9 ti\u00eau) trong JP, Ph.Eur., USP-NF<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Applications<\/h2>\n<ul>\n<li>D\u1eadp th\u1eb3ng vi\u00ean n\u00e9n: c\u1ea3i thi\u1ec7n kh\u1ea3 n\u0103ng ch\u1ecbu n\u00e9n v\u00e0 c\u1ea3m gi\u00e1c trong mi\u1ec7ng; c\u0169ng \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u cho x\u00e1t h\u1ea1t kh\u00f4 b\u1eb1ng m\u00e1y c\u00e1n.<\/li>\n<li>V\u01b0\u1ee3t tr\u1ed9i h\u1ed7n h\u1ee3p v\u1eadt l\u00fd c\u1ee7a hai th\u00e0nh ph\u1ea7n v\u1ec1 kh\u1ea3 n\u0103ng pha lo\u00e3ng (dilution potential), kh\u1ea3 n\u0103ng ch\u1ecbu n\u00e9n, \u0111\u1ed9 b\u1ec1n k\u00e9o, \u00edt nh\u1ea1y v\u1edbi t\u00e1 d\u01b0\u1ee3c tr\u01a1n v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng vi\u00ean v\u1edbi nhi\u1ec1u d\u01b0\u1ee3c ch\u1ea5t.<\/li>\n<li>\u0110\u00e3 nghi\u00ean c\u1ee9u cho nang, vi\u00ean gi\u1ea3i ph\u00f3ng c\u00f3 \u0111i\u1ec1u ch\u1ec9nh v\u00e0 l\u00e0m t\u00e1 d\u01b0\u1ee3c r\u00e3.<\/li>\n<\/ul>\n<h2>M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>B\u1ed9t tr\u1eafng t\u1edbi g\u1ea7n tr\u1eafng, kh\u00f4ng m\u00f9i; tr\u01a1n ch\u1ea3y nh\u1edd ti\u1ec3u ph\u00e2n h\u00ecnh c\u1ea7u.<\/li>\n<li>Cellactose 80: pH 4,0\u20137,0; g\u00f3c ngh\u1ec9 32\u201335\u00b0; kh\u1ed1i l\u01b0\u1ee3ng ri\u00eang bi\u1ec3u ki\u1ebfn 0,38 g\/cm\u00b3, sau g\u00f5 0,5 g\/cm\u00b3; ch\u1ec9 s\u1ed1 Hausner 1,24; m\u1ea5t kh\u1ed1i l\u01b0\u1ee3ng khi l\u00e0m kh\u00f4 \u2264 3,5%; n\u01b0\u1edbc 4\u20137%; tro sulfat \u2264 0,2%; kim lo\u1ea1i n\u1eb7ng \u2264 5 ppm.<\/li>\n<li>C\u1ee1 h\u1ea1t: \u2264 20% d\u01b0\u1edbi 32 \u00b5m; 35\u201365% d\u01b0\u1edbi 160 \u00b5m; \u2265 80% d\u01b0\u1edbi 250 \u00b5m.<\/li>\n<li>Vi sinh: t\u1ed5ng vi khu\u1ea9n hi\u1ebfu kh\u00ed d\u01b0\u1edbi 100 cfu\/g; n\u1ea5m m\u1ed1c, n\u1ea5m men m\u1ed7i lo\u1ea1i d\u01b0\u1edbi 10 cfu\/g.<\/li>\n<li>Tan m\u1ed9t ph\u1ea7n trong n\u01b0\u1edbc.<\/li>\n<\/ul>\n<h2>\u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n<p>B\u1ea3o qu\u1ea3n \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng, trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4, kh\u00f4ng c\u00f3 m\u00f9i l\u1ea1.<\/p>\n<h2>T\u01b0\u01a1ng k\u1ef5<\/h2>\n<p>Nh\u01b0 lactose monohydrat v\u00e0 cellulose b\u1ed9t.<\/p>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>\u0110\u1ed3ng s\u1ea5y phun h\u1ed7n h\u1ee3p lactose monohydrat v\u00e0 cellulose b\u1ed9t.<\/p>\n<h2>An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n<p>L\u00e0 h\u1ed7n h\u1ee3p c\u1ee7a hai th\u00e0nh ph\u1ea7n \u0111\u1ec1u \u0111\u01b0\u1ee3c coi l\u00e0 kh\u00f4ng \u0111\u1ed9c; xem lactose monohydrat v\u00e0 cellulose b\u1ed9t. Thao t\u00e1c theo l\u01b0u \u00fd th\u00f4ng th\u01b0\u1eddng.<\/p>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n<ul>\n<li>Lactose monohydrat: GRAS; c\u00f3 trong FDA IID v\u00e0 thu\u1ed1c ti\u00eam, kh\u00f4ng ti\u00eam l\u01b0u h\u00e0nh t\u1ea1i Anh.<\/li>\n<li>Cellulose b\u1ed9t: GRAS; \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn l\u00e0m ph\u1ee5 gia th\u1ef1c ph\u1ea9m t\u1ea1i ch\u00e2u \u00c2u (tr\u1eeb th\u1ef1c ph\u1ea9m cho tr\u1ebb nh\u1ecf t\u1ea1i Anh); c\u00f3 trong thu\u1ed1c kh\u00f4ng d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam l\u01b0u h\u00e0nh t\u1ea1i Anh.<\/li>\n<li>C\u1ea3 hai c\u00f3 trong Canadian Natural Health Products Ingredients Database.<\/li>\n<\/ul>\n<h2>Ch\u1ea5t li\u00ean quan<\/h2>\n<p>Lactose monohydrat, cellulose b\u1ed9t; xem th\u00eam lactose monohydrat \u2013 cellulose vi tinh th\u1ec3 \u0111\u1ed3ng x\u1eed l\u00fd (MicroceLac 100).<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<p>N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn <em>Lactose Monohydrate and Powdered Cellulose, Coprocessed<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). <em>Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) &amp; American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n<p><em>\u1ea2nh minh h\u1ecda: thi\u1ebft k\u1ebf c\u1ee7a CPC1.<\/em><\/p>\n<p><em>L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Lactose monohydrat \u2013 cellulose b\u1ed9t \u0111\u1ed3ng x\u1eed l\u00fd (Cellactose 80) \u2013 t\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng Lactose monohydrat \u2013 cellulose b\u1ed9t \u0111\u1ed3ng x\u1eed l\u00fd (t\u00ean th\u01b0\u01a1ng m\u1ea1i Cellactose 80) l\u00e0 ti\u1ec3u ph\u00e2n t\u00edch h\u1ee3p g\u1ed3m kho\u1ea3ng 75% lactose monohydrat v\u00e0 25% cellulose b\u1ed9t, t\u1ea1o b\u1eb1ng \u0111\u1ed3ng s\u1ea5y phun. S\u1ea3n ph\u1ea9m l\u00e0 t\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng v\u00e0 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3586,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3587","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/lactose-monohydrat-va-cellulose-bot-dong-xu-ly.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/lactose-monohydrat-va-cellulose-bot-dong-xu-ly-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/lactose-monohydrat-va-cellulose-bot-dong-xu-ly-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/lactose-monohydrat-va-cellulose-bot-dong-xu-ly-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/lactose-monohydrat-va-cellulose-bot-dong-xu-ly-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/lactose-monohydrat-va-cellulose-bot-dong-xu-ly.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/lactose-monohydrat-va-cellulose-bot-dong-xu-ly.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/lactose-monohydrat-va-cellulose-bot-dong-xu-ly-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Lactose monohydrat \u2013 cellulose b\u1ed9t \u0111\u1ed3ng x\u1eed l\u00fd (Cellactose 80) \u2013 t\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng Lactose monohydrat \u2013 cellulose b\u1ed9t \u0111\u1ed3ng x\u1eed l\u00fd (t\u00ean th\u01b0\u01a1ng m\u1ea1i Cellactose 80) l\u00e0 ti\u1ec3u ph\u00e2n t\u00edch h\u1ee3p g\u1ed3m kho\u1ea3ng 75% lactose monohydrat v\u00e0 25% cellulose b\u1ed9t, t\u1ea1o b\u1eb1ng \u0111\u1ed3ng s\u1ea5y phun. S\u1ea3n ph\u1ea9m l\u00e0 t\u00e1 d\u01b0\u1ee3c d\u1eadp th\u1eb3ng v\u00e0&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3587","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3587"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3587\/revisions"}],"predecessor-version":[{"id":3860,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3587\/revisions\/3860"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3586"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3587"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3587"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3587"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}