{"id":3583,"date":"2026-09-29T09:08:45","date_gmt":"2026-09-29T02:08:45","guid":{"rendered":"https:\/\/cpc1.vn\/isopropyl-isostearat\/"},"modified":"2026-09-29T12:04:02","modified_gmt":"2026-09-29T05:04:02","slug":"isopropyl-isostearat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/isopropyl-isostearat\/","title":{"rendered":"Isopropyl isostearat \u2013 ch\u1ea5t l\u00e0m m\u1ec1m, tr\u01a1n kh\u00f4ng nh\u1eddn cho kem v\u00e0 nh\u0169 t\u01b0\u01a1ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Isopropyl isostearat \u2013 ch\u1ea5t l\u00e0m m\u1ec1m, tr\u01a1n kh\u00f4ng nh\u1eddn cho kem v\u00e0 nh\u0169 t\u01b0\u01a1ng<\/h1>\n<p><strong>Isopropyl isostearat<\/strong> l\u00e0 ester c\u1ee7a alcol isopropylic v\u1edbi acid isostearic (acid b\u00e9o C18 m\u1ea1ch nh\u00e1nh), ch\u1ea5t l\u1ecfng trong, m\u00f9i nh\u1ea1t. Trong b\u00e0o ch\u1ebf, isopropyl isostearat l\u00e0 <strong>ch\u1ea5t l\u00e0m m\u1ec1m (emollient)<\/strong> cho kem v\u00e0 nh\u0169 t\u01b0\u01a1ng b\u00f4i, cho c\u1ea3m gi\u00e1c tr\u01a1n l\u00e1ng m\u00e0 kh\u00f4ng nh\u1eddn.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean kh\u00e1c<\/td>\n<td>Ester isopropyl c\u1ee7a acid isostearic, 1-methylethyl isooctadecanoat, propan-2-yl 16-methylheptadecanoat<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>68171-33-5<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\n<td>C<sub>21<\/sub>H<sub>42<\/sub>O<sub>2<\/sub> \u2013 326,56<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\n<td>Ch\u1ea5t l\u00e0m m\u1ec1m<\/td>\n<\/tr>\n<tr>\n<td>D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\n<td>Kh\u00f4ng c\u00f3 chuy\u00ean lu\u1eadn d\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Applications<\/h2>\n<ul>\n<li>Ch\u1ea5t l\u00e0m m\u1ec1m trong kem v\u00e0 nh\u0169 t\u01b0\u01a1ng b\u00f4i; nh\u0169 t\u01b0\u01a1ng gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i.<\/li>\n<li>\u0110\u01b0\u1ee3c nghi\u00ean c\u1ee9u cho h\u1ec7 cung c\u1ea5p thu\u1ed1c d\u1ea1ng ti\u1ec3u ph\u00e2n nano.<\/li>\n<li>M\u1ef9 ph\u1ea9m (d\u1ea7u t\u1eafm, kem, lotion, son m\u00f4i): \u0111i\u1ec3m \u0111\u00f4ng \u0111\u1eb7c th\u1ea5p, tr\u01a1n m\u00e0 kh\u00f4ng nh\u1eddn, d\u1ec5 t\u00e1n, t\u1ea1o \u0111\u1ed9 tr\u01b0\u1ee3t t\u1ed1t.<\/li>\n<\/ul>\n<h2>M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>Ch\u1ea5t l\u1ecfng trong, m\u00f9i nh\u1ea1t.<\/li>\n<li>T\u1ef7 tr\u1ecdng 0,86 g\/cm\u00b3; chi\u1ebft su\u1ea5t kho\u1ea3ng 1,443\u20131,445; \u0111\u1ed9 nh\u1edbt kho\u1ea3ng 15 mPa\u00b7s; s\u1ee9c c\u0103ng b\u1ec1 m\u1eb7t 29,8 mN\/m.<\/li>\n<li>\u0110i\u1ec3m s\u00f4i kho\u1ea3ng 361 \u00b0C; \u0111i\u1ec3m ch\u1edbp ch\u00e1y kho\u1ea3ng 184 \u00b0C; ch\u1ec9 s\u1ed1 x\u00e0 ph\u00f2ng h\u00f3a 160\u2013180.<\/li>\n<li>\u0110\u1ed9 tan: tan trong aceton, ethanol 95%, ethyl acetat, isopropanol, d\u1ea7u kho\u00e1ng; kh\u00f4ng tan trong n\u01b0\u1edbc, glycerol, propylen glycol.<\/li>\n<\/ul>\n<h2>\u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n<p>B\u1ec1n v\u1edbi oxy h\u00f3a v\u00e0 th\u1ee7y ph\u00e2n, kh\u00f4ng b\u1ecb \u00f4i. B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t, tr\u00e1nh \u00e1nh s\u00e1ng.<\/p>\n<h2>T\u01b0\u01a1ng k\u1ef5<\/h2>\n<p>T\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t oxy h\u00f3a m\u1ea1nh. Ti\u1ebfp x\u00fac l\u00e2u v\u1edbi nh\u1ef1a c\u00f3 th\u1ec3 l\u00e0m nh\u1ef1a m\u1ec1m ra.<\/p>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>Ester h\u00f3a acid isostearic v\u1edbi propan-2-ol c\u00f3 x\u00fac t\u00e1c.<\/p>\n<h2>An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n<ul>\n<li>H\u1ed9i \u0111\u1ed3ng CIR k\u1ebft lu\u1eadn an to\u00e0n trong m\u1ef9 ph\u1ea9m \u1edf n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a 50%. D\u1ea1ng nguy\u00ean ch\u1ea5t x\u1ebfp lo\u1ea1i k\u00edch \u1ee9ng m\u1eaft nh\u1eb9; b\u00f4i l\u1eb7p l\u1ea1i h\u1ed7n d\u1ecbch n\u01b0\u1edbc 10% tr\u00ean da th\u1ecf dung n\u1ea1p t\u1ed1t.<\/li>\n<li>LD<sub>50<\/sub> (chu\u1ed9t c\u1ed1ng, u\u1ed1ng): tr\u00ean 64 g\/kg.<\/li>\n<li>\u0110un t\u1edbi ph\u00e2n h\u1ee7y sinh kh\u00f3i cay, h\u01a1i k\u00edch \u1ee9ng. Thao t\u00e1c theo l\u01b0u \u00fd th\u00f4ng th\u01b0\u1eddng.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n<ul>\n<li>C\u00f3 trong FDA Inactive Ingredients Database (kem, nh\u0169 t\u01b0\u01a1ng gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i); c\u00f3 trong kem l\u01b0u h\u00e0nh t\u1ea1i Anh; c\u00f3 trong Canadian Natural Health Products Ingredients Database.<\/li>\n<\/ul>\n<h2>Ch\u1ea5t li\u00ean quan<\/h2>\n<ul>\n<li>Isopropyl myristat, isopropyl palmitat.<\/li>\n<li><strong>Isopropyl stearat<\/strong> (C<sub>21<\/sub>H<sub>42<\/sub>O<sub>2<\/sub>; CAS 112-10-7): ch\u1ea5t l\u00e0m m\u1ec1m, n\u00f3ng ch\u1ea3y 28 \u00b0C, t\u1ef7 tr\u1ecdng 0,861 g\/cm\u00b3, chi\u1ebft su\u1ea5t 1,445; tan trong aceton, cloroform, ethanol 95%, ethyl acetat, d\u1ea7u m\u1ee1, alcol b\u00e9o, hydrocarbon l\u1ecfng, toluen, s\u00e1p; h\u1ea7u nh\u01b0 kh\u00f4ng tan trong glycerin, glycol, n\u01b0\u1edbc.<\/li>\n<\/ul>\n<p><strong>Ghi ch\u00fa:<\/strong> s\u1ed1 EINECS 269-023-3.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<p>N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn <em>Isopropyl Isostearate<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). <em>Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) &amp; American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n<p><em>\u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n<p><em>L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Isopropyl isostearat \u2013 ch\u1ea5t l\u00e0m m\u1ec1m, tr\u01a1n kh\u00f4ng nh\u1eddn cho kem v\u00e0 nh\u0169 t\u01b0\u01a1ng Isopropyl isostearat l\u00e0 ester c\u1ee7a alcol isopropylic v\u1edbi acid isostearic (acid b\u00e9o C18 m\u1ea1ch nh\u00e1nh), ch\u1ea5t l\u1ecfng trong, m\u00f9i nh\u1ea1t. Trong b\u00e0o ch\u1ebf, isopropyl isostearat l\u00e0 ch\u1ea5t l\u00e0m m\u1ec1m (emollient) cho kem v\u00e0 nh\u0169 t\u01b0\u01a1ng b\u00f4i, cho c\u1ea3m gi\u00e1c tr\u01a1n l\u00e1ng [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3582,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3583","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/isopropyl-isostearat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/isopropyl-isostearat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/isopropyl-isostearat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/isopropyl-isostearat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/isopropyl-isostearat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/isopropyl-isostearat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/isopropyl-isostearat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/isopropyl-isostearat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Isopropyl isostearat \u2013 ch\u1ea5t l\u00e0m m\u1ec1m, tr\u01a1n kh\u00f4ng nh\u1eddn cho kem v\u00e0 nh\u0169 t\u01b0\u01a1ng Isopropyl isostearat l\u00e0 ester c\u1ee7a alcol isopropylic v\u1edbi acid isostearic (acid b\u00e9o C18 m\u1ea1ch nh\u00e1nh), ch\u1ea5t l\u1ecfng trong, m\u00f9i nh\u1ea1t. Trong b\u00e0o ch\u1ebf, isopropyl isostearat l\u00e0 ch\u1ea5t l\u00e0m m\u1ec1m (emollient) cho kem v\u00e0 nh\u0169 t\u01b0\u01a1ng b\u00f4i, cho c\u1ea3m gi\u00e1c tr\u01a1n l\u00e1ng&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3583","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3583"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3583\/revisions"}],"predecessor-version":[{"id":3848,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3583\/revisions\/3848"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3582"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3583"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3583"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3583"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}