{"id":3565,"date":"2026-09-29T09:03:43","date_gmt":"2026-09-29T02:03:43","guid":{"rendered":"https:\/\/cpc1.vn\/glycin\/"},"modified":"2026-09-29T09:03:43","modified_gmt":"2026-09-29T02:03:43","slug":"glycin","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/glycin\/","title":{"rendered":"Glycin \u2013 t\u00e1 d\u01b0\u1ee3c \u0111\u00f4ng kh\u00f4, ch\u1ea5t \u0111\u1ec7m, t\u0103ng r\u00e3 vi\u00ean"},"content":{"rendered":"

Glycin \u2013 t\u00e1 d\u01b0\u1ee3c \u0111\u00f4ng kh\u00f4, ch\u1ea5t \u0111\u1ec7m, t\u0103ng r\u00e3 vi\u00ean<\/h1>\n

Glycin<\/strong> (acid aminoacetic, E640) l\u00e0 acid amin \u0111\u01a1n gi\u1ea3n nh\u1ea5t, d\u1ea1ng b\u1ed9t k\u1ebft tinh tr\u1eafng, v\u1ecb ng\u1ecdt. Trong b\u00e0o ch\u1ebf, glycin l\u00e0 m\u1ed9t trong nh\u1eefng t\u00e1 d\u01b0\u1ee3c \u0111\u00f4ng kh\u00f4<\/strong> d\u00f9ng nhi\u1ec1u nh\u1ea5t cho thu\u1ed1c ti\u00eam protein \u2013 t\u1ea1o b\u00e1nh \u0111\u00f4ng kh\u00f4 ch\u1eafc, x\u1ed1p, \u0111\u1eb9p \u2013 \u0111\u1ed3ng th\u1eddi l\u00e0 ch\u1ea5t \u0111\u1ec7m<\/strong> v\u00e0 ch\u1ea5t t\u0103ng r\u00e3<\/strong> cho vi\u00ean r\u00e3 nhanh.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nAcid aminoacetic, acid 2-aminoacetic, glycocoll, Gly, E640<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n56-40-6<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC2<\/sub>H5<\/sub>NO2<\/sub> \u2013 75,07<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t \u0111\u1ec7m, t\u00e1 d\u01b0\u1ee3c \u0111\u00f4ng kh\u00f4, t\u00e1 d\u01b0\u1ee3c r\u00e3 vi\u00ean n\u00e9n\/vi\u00ean nang<\/td>\n<\/tr>\n
D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nBP, JP, Ph.Eur., USP-NF<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • T\u00e1 d\u01b0\u1ee3c \u0111\u1ed3ng \u0111\u00f4ng kh\u00f4 trong c\u00f4ng th\u1ee9c protein: t\u1ea1o b\u00e1nh \u0111\u00f4ng kh\u00f4 ch\u1eafc, x\u1ed1p, \u0111\u1eb9p; l\u00e0 m\u1ed9t trong nh\u1eefng t\u00e1 d\u01b0\u1ee3c th\u00f4ng d\u1ee5ng nh\u1ea5t c\u1ee7a thu\u1ed1c ti\u00eam \u0111\u00f4ng kh\u00f4.<\/li>\n
  • \u1ed4n \u0111\u1ecbnh ch\u1ebf ph\u1ea9m immunoglobulin t\u0129nh m\u1ea1ch (IVIG) kh\u00f4ng \u0111\u01b0\u1eddng.<\/li>\n
  • \u1ede n\u1ed3ng \u0111\u1ed9 th\u1ea5p (d\u01b0\u1edbi 50 mmol\/L), glycin h\u1ea1n ch\u1ebf r\u00f5 hi\u1ec7n t\u01b0\u1ee3ng t\u1ee5t pH c\u1ee7a \u0111\u1ec7m natri phosphat khi \u0111\u00f4ng l\u1ea1nh \u2013 y\u1ebfu t\u1ed1 b\u1ea5t l\u1ee3i cho \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh protein.<\/li>\n
  • T\u0103ng r\u00e3 cho d\u1ea1ng r\u00e3 nhanh nh\u1edd h\u00f2a tan nhanh trong n\u01b0\u1edbc; \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u trong c\u00f4ng th\u1ee9c s\u1ea5y phun.<\/li>\n
  • Th\u1ef1c ph\u1ea9m b\u1ed5 sung, ch\u1ea5t t\u1ea1o ng\u1ecdt; ch\u1ea5t \u0111\u1ec7m v\u00e0 d\u01b0\u1ee1ng trong m\u1ef9 ph\u1ea9m.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • B\u1ed9t k\u1ebft tinh tr\u1eafng, kh\u00f4ng m\u00f9i, v\u1ecb ng\u1ecdt.<\/li>\n
    • pH dung d\u1ecbch 0,2 M kho\u1ea3ng 4 (d\u01b0\u1ee3c \u0111i\u1ec3n: pH 5,6\u20136,6 t\u00f9y chuy\u00ean lu\u1eadn); t\u1ef7 tr\u1ecdng 1,1607 g\/cm\u00b3; \u0111i\u1ec3m ch\u1ea3y 232\u2013236 \u00b0C.<\/li>\n
    • \u0110a h\u00ecnh: glycin khan c\u00f3 ba d\u1ea1ng \u03b1, \u03b2, \u03b3. \u0110\u00f4ng kh\u00f4 th\u01b0\u1eddng t\u1ea1o d\u1ea1ng \u03b2; h\u01a1i \u1ea9m \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng c\u00f3 th\u1ec3 chuy\u1ec3n th\u00e0nh h\u1ed7n h\u1ee3p \u03b1 v\u00e0 \u03b3 \u2013 c\u1ea7n l\u01b0u \u00fd v\u1edbi \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh b\u00e1nh \u0111\u00f4ng kh\u00f4.<\/li>\n<\/ul>\n\n\n\n\n\n\n\n\n
      Dung m\u00f4i<\/th>\n\u0110\u1ed9 tan<\/th>\n<\/tr>\n<\/thead>\n
      N\u01b0\u1edbc<\/td>\n1 trong 4 (25 \u00b0C); 1 trong 2,6 (50 \u00b0C); 1 trong 1,5 (100 \u00b0C)<\/td>\n<\/tr>\n
      Pyridin<\/td>\n1 trong 164<\/td>\n<\/tr>\n
      Ethanol 95%<\/td>\n1 trong 1254<\/td>\n<\/tr>\n
      Ether<\/td>\nR\u1ea5t kh\u00f3 tan ho\u1eb7c h\u1ea7u nh\u01b0 kh\u00f4ng tan<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1eaft \u0111\u1ea7u ph\u00e2n h\u1ee7y \u1edf 233 \u00b0C. B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn. Dung d\u1ecbch r\u1eeda glycin \u0111\u1ef1ng trong bao b\u00ec \u0111\u01a1n li\u1ec1u, \u01b0u ti\u00ean th\u1ee7y tinh lo\u1ea1i I ho\u1eb7c II.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      C\u00f3 th\u1ec3 tham gia ph\u1ea3n \u1ee9ng Maillard g\u00e2y ng\u1ea3 v\u00e0ng, n\u00e2u. \u0110\u01b0\u1eddng kh\u1eed c\u00f3 th\u1ec3 t\u1ea1o imin v\u1edbi amin b\u1eadc hai m\u00e0 kh\u00f4ng k\u00e8m \u0111\u1ed5i m\u00e0u.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      T\u1ed5ng h\u1ee3p h\u00f3a h\u1ecdc l\u00e0 ph\u00f9 h\u1ee3p nh\u1ea5t: amin h\u00f3a acid cloroacetic ho\u1eb7c th\u1ee7y ph\u00e2n aminoacetonitril.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
        \n
      • D\u00f9ng l\u00e0m ch\u1ea5t t\u1ea1o ng\u1ecdt, ch\u1ea5t \u0111\u1ec7m, th\u1ef1c ph\u1ea9m b\u1ed5 sung. \u1ede d\u1ea1ng tinh khi\u1ebft \u0111\u1ed9c v\u1eeba qua \u0111\u01b0\u1eddng t\u0129nh m\u1ea1ch v\u00e0 \u0111\u1ed9c nh\u1eb9 khi nu\u1ed1t.<\/li>\n
      • H\u1ea5p thu to\u00e0n th\u00e2n dung d\u1ecbch r\u1eeda glycin c\u00f3 th\u1ec3 g\u00e2y r\u1ed1i lo\u1ea1n n\u01b0\u1edbc \u2013 \u0111i\u1ec7n gi\u1ea3i, r\u1ed1i lo\u1ea1n tim m\u1ea1ch v\u00e0 h\u00f4 h\u1ea5p; IVIG \u1ed5n \u0111\u1ecbnh b\u1eb1ng glycin c\u00f3 th\u1ec3 g\u00e2y suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn th\u1ee9 ph\u00e1t.<\/li>\n
      • LD50<\/sub> (chu\u1ed9t nh\u1eaft): ph\u00fac m\u1ea1c 4,45 g\/kg; t\u0129nh m\u1ea1ch 2,37 g\/kg; u\u1ed1ng 4,92 g\/kg; d\u01b0\u1edbi da 5,06 g\/kg. (Chu\u1ed9t c\u1ed1ng): t\u0129nh m\u1ea1ch 2,6 g\/kg; u\u1ed1ng 7,93 g\/kg; d\u01b0\u1edbi da 5,2 g\/kg.<\/li>\n
      • \u0110un t\u1edbi ph\u00e2n h\u1ee7y sinh kh\u00f3i \u0111\u1ed9c oxyd nit\u01a1.<\/li>\n<\/ul>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • C\u00f3 trong FDA Inactive Ingredients Database (ti\u00eam b\u1eafp, t\u0129nh m\u1ea1ch, d\u01b0\u1edbi da; u\u1ed1ng; tr\u1ef1c tr\u00e0ng).<\/li>\n
        • C\u00f3 trong thu\u1ed1c l\u01b0u h\u00e0nh t\u1ea1i Anh: b\u1ed9t pha ti\u00eam, dung d\u1ecbch ti\u00eam, vaccin, b\u1ed9 c\u1ea5y gh\u00e9p; vi\u00ean ph\u00e2n t\u00e1n trong mi\u1ec7ng, b\u1ed9t h\u00edt, b\u1ed9t pha dung d\u1ecbch u\u1ed1ng, vi\u00ean n\u00e9n.<\/li>\n
        • C\u00f3 trong Canadian Natural Health Products Ingredients Database; \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn l\u00e0m ph\u1ee5 gia th\u1ef1c ph\u1ea9m t\u1ea1i ch\u00e2u \u00c2u; c\u00f3 ti\u00eau chu\u1ea9n trong Food Chemicals Codex.<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan<\/h2>\n
            \n
          • Glycin hydroclorid<\/strong> (C2<\/sub>H5<\/sub>NO2<\/sub>\u00b7HCl, KLPT 111,5; CAS 6000-43-7; n\u00f3ng ch\u1ea3y 182 \u00b0C).<\/li>\n
          • Natri glycinat<\/strong> (C2<\/sub>H4<\/sub>NO2<\/sub>Na, KLPT 97,1; CAS 6000-44-8; n\u00f3ng ch\u1ea3y 197\u2013201 \u00b0C).<\/li>\n<\/ul>\n

            Ghi ch\u00fa:<\/strong> dung d\u1ecbch r\u1eeda glycin 1,5% (USP) d\u00f9ng trong ti\u1ebft ni\u1ec7u; glycin c\u00f2n c\u00f3 c\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c \u2013 n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. S\u1ed1 EINECS 200-272-2; PubChem CID 750.<\/p>\n

            Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

            N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Glycine<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

            \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

            L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

            Glycin \u2013 t\u00e1 d\u01b0\u1ee3c \u0111\u00f4ng kh\u00f4, ch\u1ea5t \u0111\u1ec7m, t\u0103ng r\u00e3 vi\u00ean Glycin (acid aminoacetic, E640) l\u00e0 acid amin \u0111\u01a1n gi\u1ea3n nh\u1ea5t, d\u1ea1ng b\u1ed9t k\u1ebft tinh tr\u1eafng, v\u1ecb ng\u1ecdt. Trong b\u00e0o ch\u1ebf, glycin l\u00e0 m\u1ed9t trong nh\u1eefng t\u00e1 d\u01b0\u1ee3c \u0111\u00f4ng kh\u00f4 d\u00f9ng nhi\u1ec1u nh\u1ea5t cho thu\u1ed1c ti\u00eam protein \u2013 t\u1ea1o b\u00e1nh \u0111\u00f4ng kh\u00f4 ch\u1eafc, x\u1ed1p, \u0111\u1eb9p […]<\/p>\n","protected":false},"author":1,"featured_media":3564,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3565","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycin.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycin-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycin-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycin-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycin-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycin.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycin.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycin-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Glycin \u2013 t\u00e1 d\u01b0\u1ee3c \u0111\u00f4ng kh\u00f4, ch\u1ea5t \u0111\u1ec7m, t\u0103ng r\u00e3 vi\u00ean Glycin (acid aminoacetic, E640) l\u00e0 acid amin \u0111\u01a1n gi\u1ea3n nh\u1ea5t, d\u1ea1ng b\u1ed9t k\u1ebft tinh tr\u1eafng, v\u1ecb ng\u1ecdt. Trong b\u00e0o ch\u1ebf, glycin l\u00e0 m\u1ed9t trong nh\u1eefng t\u00e1 d\u01b0\u1ee3c \u0111\u00f4ng kh\u00f4 d\u00f9ng nhi\u1ec1u nh\u1ea5t cho thu\u1ed1c ti\u00eam protein \u2013 t\u1ea1o b\u00e1nh \u0111\u00f4ng kh\u00f4 ch\u1eafc, x\u1ed1p, \u0111\u1eb9p…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3565","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3565"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3565\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3564"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3565"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3565"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3565"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}