{"id":3557,"date":"2026-09-29T09:01:34","date_gmt":"2026-09-29T02:01:34","guid":{"rendered":"https:\/\/cpc1.vn\/galactose\/"},"modified":"2026-09-29T09:01:34","modified_gmt":"2026-09-29T02:01:34","slug":"galactose","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/galactose\/","title":{"rendered":"Galactose \u2013 ch\u1ea5t t\u1ea1o ng\u1ecdt, ph\u1ed1i t\u1eed h\u01b0\u1edbng gan trong h\u1ec7 nano"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Galactose \u2013 ch\u1ea5t t\u1ea1o ng\u1ecdt, ph\u1ed1i t\u1eed h\u01b0\u1edbng gan trong h\u1ec7 nano<\/h1>\n<p><strong>Galactose<\/strong> l\u00e0 monosaccharid 6 carbon, \u0111\u1ed3ng ph\u00e2n c\u1ee7a glucose, c\u00f9ng glucose c\u1ea5u th\u00e0nh lactose (\u0111\u01b0\u1eddng s\u1eefa). Trong b\u00e0o ch\u1ebf, galactose \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m <strong>ch\u1ea5t t\u1ea1o ng\u1ecdt<\/strong> cho thu\u1ed1c u\u1ed1ng; g\u1ea7n \u0111\u00e2y c\u00f2n \u0111\u01b0\u1ee3c g\u1eafn l\u00ean ti\u1ec3u ph\u00e2n nano v\u00e0 li\u00ean h\u1ee3p polymer \u2013 thu\u1ed1c l\u00e0m <strong>ph\u1ed1i t\u1eed h\u01b0\u1edbng \u0111\u00edch t\u1edbi gan<\/strong>.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean kh\u00e1c<\/td>\n<td>D-Galactose, galactosum, cerebrose, lactoglucose<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>3646-73-9 (\u03b1-D-galactopyranose, theo USP-NF); 59-23-4 (D-galactopyranose, theo Ph.Eur.)<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\n<td>C<sub>6<\/sub>H<sub>12<\/sub>O<sub>6<\/sub> \u2013 180,16<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\n<td>Ch\u1ea5t t\u1ea1o ph\u1ee9c, ch\u1ea5t t\u1ea1o ng\u1ecdt<\/td>\n<\/tr>\n<tr>\n<td>D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\n<td>BP, Ph.Eur., USP-NF<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Applications<\/h2>\n<ul>\n<li>Ch\u1ea5t t\u1ea1o ng\u1ecdt trong ch\u1ebf ph\u1ea9m u\u1ed1ng.<\/li>\n<li>Ph\u1ed1i t\u1eed h\u01b0\u1edbng gan: ti\u1ec3u ph\u00e2n nano \u0111\u1ed3ng tr\u00f9ng h\u1ee3p c\u00f3 \u0111\u1ea7u m\u1ea1ch g\u1eafn galactose v\u00e0 li\u00ean h\u1ee3p polymer \u2013 thu\u1ed1c ch\u1ee9a galactose \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u \u0111\u1ec3 \u0111\u01b0a thu\u1ed1c \u0111\u1eb7c hi\u1ec7u t\u1edbi gan.<\/li>\n<li>Dung d\u1ecbch ho\u1eb7c vi h\u1ea1t galactose \u1ed5n \u0111\u1ecbnh b\u1eb1ng acid palmitic ph\u00e2n t\u00e1n trong n\u01b0\u1edbc \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m ch\u1ea5t t\u01b0\u01a1ng ph\u1ea3n si\u00eau \u00e2m.<\/li>\n<\/ul>\n<h2>M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>B\u1ed9t k\u1ebft tinh ho\u1eb7c h\u1ea1t m\u1ecbn, tr\u1eafng ho\u1eb7c g\u1ea7n tr\u1eafng.<\/li>\n<li>\u0110i\u1ec3m ch\u1ea3y kho\u1ea3ng 163\u2013170 \u00b0C; t\u1ef7 tr\u1ecdng kho\u1ea3ng 1,5 g\/cm\u00b3; pKa 12,92; pH dung d\u1ecbch n\u01b0\u1edbc 4,5\u20136,0.<\/li>\n<li>Quay c\u1ef1c trong n\u01b0\u1edbc c\u00f3 hi\u1ec7n t\u01b0\u1ee3ng bi\u1ebfn quay: d\u1ea1ng \u03b1 t\u1eeb +150,7\u00b0 v\u00e0 d\u1ea1ng \u03b2 t\u1eeb +52,8\u00b0 \u0111\u1ec1u ti\u1ebfn v\u1ec1 +80,2\u00b0 khi c\u00e2n b\u1eb1ng.<\/li>\n<li>\u0110\u1ed9 tan: d\u1ea1ng \u03b1 tan trong 0,5 ph\u1ea7n n\u01b0\u1edbc, d\u1ea1ng \u03b2 trong 1,7 ph\u1ea7n n\u01b0\u1edbc (c\u00e1c t\u00e0i li\u1ec7u kh\u00e1c ghi 47\u201368 g\/100 g n\u01b0\u1edbc); tan trong pyridin.<\/li>\n<\/ul>\n<h2>\u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n<p>B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t, th\u00f4ng tho\u00e1ng.<\/p>\n<h2>T\u01b0\u01a1ng k\u1ef5<\/h2>\n<p>L\u00e0 \u0111\u01b0\u1eddng kh\u1eed, c\u00f3 th\u1ec3 tham gia ph\u1ea3n \u1ee9ng Maillard v\u1edbi amin.<\/p>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>Ch\u1ee7 y\u1ebfu th\u1ee7y ph\u00e2n lactose (disaccharid g\u1ed3m glucose v\u00e0 galactose) c\u00f3 trong s\u1eefa. D-galactose kh\u00f4ng c\u00f3 ngu\u1ed3n g\u1ed1c \u0111\u1ed9ng v\u1eadt \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t t\u1eeb d\u1ecbch th\u1ee7y ph\u00e2n g\u1ed7 ho\u1eb7c sinh kh\u1ed1i kh\u00e1c b\u1eb1ng s\u1eafc k\u00fd t\u00e1ch trong m\u00f4i tr\u01b0\u1eddng n\u01b0\u1edbc.<\/p>\n<h2>An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n<ul>\n<li>Nh\u00ecn chung \u0111\u01b0\u1ee3c coi l\u00e0 an to\u00e0n, d\u00f9 th\u1ef1c nghi\u1ec7m t\u1eebng ghi nh\u1eadn t\u00e1c d\u1ee5ng g\u00e2y qu\u00e1i thai ho\u1eb7c \u0111\u1ed9t bi\u1ebfn. Li\u1ec1u l\u1edbn c\u00f3 th\u1ec3 g\u00e2y r\u1ed1i lo\u1ea1n ti\u00eau h\u00f3a.<\/li>\n<li>H\u00edt b\u1ee5i c\u00f3 th\u1ec3 k\u00edch \u1ee9ng h\u00f4 h\u1ea5p; d\u00ednh m\u1eaft ho\u1eb7c ti\u1ebfp x\u00fac da k\u00e9o d\u00e0i c\u00f3 th\u1ec3 k\u00edch \u1ee9ng. Ng\u01b0\u1eddi m\u1eafc b\u1ec7nh galactose huy\u1ebft (galactosemia \u2013 r\u1ed1i lo\u1ea1n di truy\u1ec1n hi\u1ebfm, kh\u00f4ng chuy\u1ec3n \u0111\u01b0\u1ee3c galactose th\u00e0nh glucose) c\u1ea7n \u0111\u1eb7c bi\u1ec7t l\u01b0u \u00fd.<\/li>\n<li>\u0110un t\u1edbi ph\u00e2n h\u1ee7y sinh kh\u00f3i cay, k\u00edch \u1ee9ng. Tr\u00e1nh t\u1ea1o v\u00e0 h\u00edt b\u1ee5i; n\u00ean d\u00f9ng b\u1ea3o h\u1ed9 m\u1eaft, h\u00f4 h\u1ea5p v\u00e0 da.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n<ul>\n<li>C\u00f3 trong FDA Inactive Ingredients Database (dung d\u1ecbch, vi\u00ean n\u00e9n u\u1ed1ng; dung d\u1ecbch tr\u1ef1c tr\u00e0ng) v\u00e0 Canadian Natural Health Products Ingredients Database.<\/li>\n<li>C\u00f3 chuy\u00ean lu\u1eadn trong BP, Ph.Eur., USP-NF.<\/li>\n<\/ul>\n<h2>Ch\u1ea5t li\u00ean quan<\/h2>\n<p>G\u00f4m guar, lactose monohydrat, raffinose.<\/p>\n<p><strong>Ghi ch\u00fa:<\/strong> trong t\u1ef1 nhi\u00ean galactose th\u01b0\u1eddng \u1edf d\u1ea1ng k\u1ebft h\u1ee3p: trong lactose, trong c\u00e1c polysaccharid (g\u00f4m) v\u00e0 glycolipid c\u1ee7a m\u00f4 th\u1ea7n kinh. Galactose c\u00f2n c\u00f3 \u1ee9ng d\u1ee5ng y khoa (th\u0103m d\u00f2 ch\u1ee9c n\u0103ng gan, si\u00eau \u00e2m tim) \u2013 n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. S\u1ed1 EINECS 200-416-4; PubChem CID 439357 (\u03b1-D-galactose), 6036 (D-galactose).<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<p>N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn <em>Galactose<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). <em>Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) &amp; American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n<p><em>\u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n<p><em>L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Galactose \u2013 ch\u1ea5t t\u1ea1o ng\u1ecdt, ph\u1ed1i t\u1eed h\u01b0\u1edbng gan trong h\u1ec7 nano Galactose l\u00e0 monosaccharid 6 carbon, \u0111\u1ed3ng ph\u00e2n c\u1ee7a glucose, c\u00f9ng glucose c\u1ea5u th\u00e0nh lactose (\u0111\u01b0\u1eddng s\u1eefa). Trong b\u00e0o ch\u1ebf, galactose \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m ch\u1ea5t t\u1ea1o ng\u1ecdt cho thu\u1ed1c u\u1ed1ng; g\u1ea7n \u0111\u00e2y c\u00f2n \u0111\u01b0\u1ee3c g\u1eafn l\u00ean ti\u1ec3u ph\u00e2n nano v\u00e0 li\u00ean h\u1ee3p polymer \u2013 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3556,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3557","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/galactose.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/galactose-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/galactose-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/galactose-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/galactose-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/galactose.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/galactose.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/galactose-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Galactose \u2013 ch\u1ea5t t\u1ea1o ng\u1ecdt, ph\u1ed1i t\u1eed h\u01b0\u1edbng gan trong h\u1ec7 nano Galactose l\u00e0 monosaccharid 6 carbon, \u0111\u1ed3ng ph\u00e2n c\u1ee7a glucose, c\u00f9ng glucose c\u1ea5u th\u00e0nh lactose (\u0111\u01b0\u1eddng s\u1eefa). Trong b\u00e0o ch\u1ebf, galactose \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m ch\u1ea5t t\u1ea1o ng\u1ecdt cho thu\u1ed1c u\u1ed1ng; g\u1ea7n \u0111\u00e2y c\u00f2n \u0111\u01b0\u1ee3c g\u1eafn l\u00ean ti\u1ec3u ph\u00e2n nano v\u00e0 li\u00ean h\u1ee3p polymer \u2013&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3557","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3557"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3557\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3556"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3557"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3557"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3557"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}