{"id":3549,"date":"2026-09-29T08:41:02","date_gmt":"2026-09-29T01:41:02","guid":{"rendered":"https:\/\/cpc1.vn\/dipropylen-glycol\/"},"modified":"2026-09-29T12:00:25","modified_gmt":"2026-09-29T05:00:25","slug":"dipropylen-glycol","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/dipropylen-glycol\/","title":{"rendered":"Dipropylen glycol (DPG) \u2013 dung m\u00f4i, ch\u1ea5t gi\u1eef \u1ea9m, h\u00f3a d\u1ebbo keo d\u00e1n mi\u1ebfng d\u00e1n"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Dipropylen glycol (DPG) \u2013 dung m\u00f4i, ch\u1ea5t gi\u1eef \u1ea9m, h\u00f3a d\u1ebbo keo d\u00e1n mi\u1ebfng d\u00e1n<\/h1>\n<p><strong>Dipropylen glycol<\/strong> (DPG) l\u00e0 ch\u1ea5t l\u1ecfng kh\u00f4ng m\u00e0u, g\u1ea7n nh\u01b0 kh\u00f4ng m\u00f9i, s\u1ea3n ph\u1ea9m ph\u1ee5 c\u1ee7a qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t propylen glycol. Trong b\u00e0o ch\u1ebf, DPG \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m <strong>dung m\u00f4i<\/strong>, <strong>ch\u1ea5t gi\u1eef \u1ea9m<\/strong>, <strong>ch\u1ea5t h\u00f3a d\u1ebbo<\/strong> v\u00e0 th\u00e0nh ph\u1ea7n <strong>keo d\u00e1n<\/strong> c\u1ee7a mi\u1ebfng d\u00e1n ni\u00eam m\u1ea1c m\u00e1 v\u00e0 mi\u1ebfng d\u00e1n qua da gi\u1ea3i ph\u00f3ng c\u00f3 ki\u1ec3m so\u00e1t.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean kh\u00e1c<\/td>\n<td>DPG, oxydipropanol, oxybispropanol, 4-oxa-2,6-heptandiol<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>25265-71-8 (h\u1ed7n h\u1ee3p \u0111\u1ed3ng ph\u00e2n th\u01b0\u01a1ng m\u1ea1i); 110-98-5 (1,1&#8242;-oxybis(2-propanol) \u2013 \u0111\u1ed3ng ph\u00e2n ch\u00ednh); 108-61-2; 106-62-7<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\n<td>C<sub>6<\/sub>H<sub>14<\/sub>O<sub>3<\/sub> \u2013 134,2<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\n<td>Ch\u1ea5t gi\u1eef \u1ea9m, ch\u1ea5t h\u00f3a d\u1ebbo, dung m\u00f4i, th\u00e0nh ph\u1ea7n h\u1ec7 tr\u1ecb li\u1ec7u qua da<\/td>\n<\/tr>\n<tr>\n<td>D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\n<td>Kh\u00f4ng c\u00f3 chuy\u00ean lu\u1eadn d\u01b0\u1ee3c \u0111i\u1ec3n; c\u00f3 ti\u00eau chu\u1ea9n trong JPE<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>\u0110\u1ed3ng ph\u00e2n<\/h2>\n<p>DPG c\u00f3 ba \u0111\u1ed3ng ph\u00e2n c\u1ea5u t\u1ea1o: (a) 1,1&#8242;-oxybis(2-propanol) \u2013 \u0111\u1ed3ng ph\u00e2n chi\u1ebfm \u01b0u th\u1ebf; (b) 2,2&#8242;-oxybis(1-propanol); (c) 2-(2-hydroxypropoxy)propanol. S\u1ea3n ph\u1ea9m th\u01b0\u01a1ng m\u1ea1i (d, oxybispropanol) l\u00e0 h\u1ed7n h\u1ee3p \u0111\u1ed3ng ph\u00e2n t\u00f9y quy tr\u00ecnh s\u1ea3n xu\u1ea5t.<\/p>\n<h2>Applications<\/h2>\n<ul>\n<li>Th\u00e0nh ph\u1ea7n c\u1ee7a l\u1edbp keo d\u00e1n trong mi\u1ebfng d\u00e1n ni\u00eam m\u1ea1c m\u00e1 v\u00e0 mi\u1ebfng d\u00e1n qua da gi\u1ea3i ph\u00f3ng c\u00f3 ki\u1ec3m so\u00e1t.<\/li>\n<li>M\u1ef9 ph\u1ea9m: s\u1ea3n ph\u1ea9m l\u00e0m s\u1ea1ch da, l\u0103n kh\u1eed m\u00f9i, son m\u00f4i, n\u01b0\u1edbc hoa.<\/li>\n<li>C\u00f4ng nghi\u1ec7p: d\u1ea7u c\u1eaft g\u1ecdt, x\u00e0 ph\u00f2ng c\u00f4ng nghi\u1ec7p, thu\u1ed1c tr\u1eeb s\u00e2u; ph\u1ee5 gia nhi\u00ean li\u1ec7u (b\u00f4i tr\u01a1n, ch\u1ed1ng \u0111\u00f4ng); dung m\u00f4i m\u1ef1c in, s\u01a1n, l\u1edbp ph\u1ee7.<\/li>\n<\/ul>\n<h2>M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<p>S\u1ed1 li\u1ec7u cho \u0111\u1ed3ng ph\u00e2n ch\u00ednh (a) v\u00e0 h\u1ed7n h\u1ee3p \u0111\u1ed3ng ph\u00e2n (d):<\/p>\n<ul>\n<li>Ch\u1ea5t l\u1ecfng kh\u00f4ng m\u00e0u, g\u1ea7n nh\u01b0 kh\u00f4ng m\u00f9i.<\/li>\n<li>\u0110i\u1ec3m s\u00f4i 228\u2013233 \u00b0C; \u0111i\u1ec3m \u0111\u00f4ng \u0111\u1eb7c kho\u1ea3ng \u221239 \u00b0C; \u0111i\u1ec3m ch\u1edbp ch\u00e1y 121\u2013124 \u00b0C (c\u1ed1c k\u00edn).<\/li>\n<li>T\u1ef7 tr\u1ecdng 1,023 g\/cm\u00b3 (20 \u00b0C); chi\u1ebft su\u1ea5t 1,438\u20131,442; s\u1ee9c c\u0103ng b\u1ec1 m\u1eb7t 35 mN\/m; log P (octanol\/n\u01b0\u1edbc) kho\u1ea3ng \u22121,1 t\u1edbi \u22121,5.<\/li>\n<li>\u0110\u1ed9 nh\u1edbt 75,0 mPa\u00b7s \u1edf 25 \u00b0C; 10,9 mPa\u00b7s \u1edf 60 \u00b0C.<\/li>\n<li>Tr\u1ed9n l\u1eabn v\u1edbi n\u01b0\u1edbc, d\u1ea7u v\u00e0 hydrocarbon.<\/li>\n<li>JPE: t\u1ef7 tr\u1ecdng 1,021\u20131,027; kho\u1ea3ng c\u1ea5t 220\u2013240 \u00b0C (\u2265 95,0% th\u1ec3 t\u00edch).<\/li>\n<\/ul>\n<h2>\u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n<p>B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, tr\u00e1nh tia UV, d\u01b0\u1edbi 40 \u00b0C.<\/p>\n<h2>T\u01b0\u01a1ng k\u1ef5<\/h2>\n<p>T\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t oxy h\u00f3a m\u1ea1nh.<\/p>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>L\u00e0 s\u1ea3n ph\u1ea9m ph\u1ee5 c\u1ee7a qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t propylen glycol.<\/p>\n<h2>An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n<ul>\n<li>Kh\u00f4ng \u0111\u1ed9c c\u1ea5p qua \u0111\u01b0\u1eddng u\u1ed1ng, qua da hay h\u00f4 h\u1ea5p. U\u1ed1ng li\u1ec1u cao c\u00f3 th\u1ec3 g\u00e2y \u1ee9c ch\u1ebf th\u1ea7n kinh trung \u01b0\u01a1ng (m\u1ec7t, ch\u00f3ng m\u1eb7t, gi\u1ea3m t\u1eadp trung); \u0111\u00e3 ghi nh\u1eadn ca suy th\u1eadn c\u1ea5p, b\u1ec7nh th\u1ea7n kinh v\u00e0 b\u1ec7nh c\u01a1 \u1edf ng\u01b0\u1eddi u\u1ed1ng dung d\u1ecbch t\u1ea1o kh\u00f3i c\u00f3 DPG.<\/li>\n<li>H\u01a1i k\u00edch \u1ee9ng da, m\u1eaft; kh\u1ea3 n\u0103ng g\u00e2y d\u1ecb \u1ee9ng da th\u1ea5p. Kh\u00f4ng g\u00e2y \u0111\u1ed9c t\u00ednh di truy\u1ec1n; nghi\u00ean c\u1ee9u tr\u00ean chu\u1ed9t cho th\u1ea5y kh\u1ea3 n\u0103ng g\u00e2y ung th\u01b0 h\u1ea1n ch\u1ebf.<\/li>\n<li>LD<sub>50<\/sub> (\u0111\u01b0\u1eddng u\u1ed1ng): chu\u1ed9t c\u1ed1ng 14,85 g\/kg; chu\u1ed9t lang 17,6 g\/kg. T\u0129nh m\u1ea1ch: ch\u00f3 11,5 g\/kg; chu\u1ed9t c\u1ed1ng 5,8 g\/kg. Ph\u00fac m\u1ea1c: chu\u1ed9t nh\u1eaft 4,5 g\/kg; chu\u1ed9t c\u1ed1ng 10,0 g\/kg. LC<sub>50<\/sub> (chu\u1ed9t c\u1ed1ng, h\u00edt): 6,0 g\/m\u00b3.<\/li>\n<li>M\u1eb7c \u0111\u1ed3 b\u1ea3o h\u1ed9 ph\u00f9 h\u1ee3p; n\u00ean \u0111eo k\u00ednh b\u1ea3o h\u1ed9.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n<ul>\n<li>GRAS. H\u1ed7n h\u1ee3p \u0111\u1ed3ng ph\u00e2n (d) c\u00f3 trong FDA Inactive Ingredients Database (mi\u1ebfng d\u00e1n ni\u00eam m\u1ea1c m\u00e1; m\u00e0ng v\u00e0 mi\u1ebfng d\u00e1n qua da) v\u00e0 Canadian Natural Health Products Ingredients Database (dung m\u00f4i); c\u00f3 trong thu\u1ed1c kh\u00f4ng d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam l\u01b0u h\u00e0nh t\u1ea1i Anh.<\/li>\n<li>Ch\u01b0a \u0111\u01b0\u1ee3c ph\u00e9p l\u00e0m ph\u1ee5 gia th\u1ef1c ph\u1ea9m tr\u1ef1c ti\u1ebfp; t\u1ea1i M\u1ef9 \u0111\u01b0\u1ee3c d\u00f9ng trong v\u1eadt li\u1ec7u ti\u1ebfp x\u00fac th\u1ef1c ph\u1ea9m (keo d\u00e1n, gi\u1ea5y); t\u1ea1i EU \u0111\u01b0\u1ee3c ph\u00e9p trong v\u1eadt li\u1ec7u nh\u1ef1a ti\u1ebfp x\u00fac th\u1ef1c ph\u1ea9m.<\/li>\n<\/ul>\n<h2>Ch\u1ea5t li\u00ean quan<\/h2>\n<p>Polyethylen glycol, propylen glycol.<\/p>\n<p><strong>Ghi ch\u00fa:<\/strong> s\u1ed1 EINECS (a) 203-821-4, (b) 203-599-9, (c) 203-416-2, (d) 246-770-3; PubChem CID (a) 8087, (d) 32857.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<p>N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn <em>Dipropylene Glycol<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). <em>Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) &amp; American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n<p><em>\u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n<p><em>L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Dipropylen glycol (DPG) \u2013 dung m\u00f4i, ch\u1ea5t gi\u1eef \u1ea9m, h\u00f3a d\u1ebbo keo d\u00e1n mi\u1ebfng d\u00e1n Dipropylen glycol (DPG) l\u00e0 ch\u1ea5t l\u1ecfng kh\u00f4ng m\u00e0u, g\u1ea7n nh\u01b0 kh\u00f4ng m\u00f9i, s\u1ea3n ph\u1ea9m ph\u1ee5 c\u1ee7a qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t propylen glycol. Trong b\u00e0o ch\u1ebf, DPG \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m dung m\u00f4i, ch\u1ea5t gi\u1eef \u1ea9m, ch\u1ea5t h\u00f3a d\u1ebbo v\u00e0 th\u00e0nh ph\u1ea7n [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3548,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3549","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dipropylen-glycol.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dipropylen-glycol-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dipropylen-glycol-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dipropylen-glycol-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dipropylen-glycol-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dipropylen-glycol.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dipropylen-glycol.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dipropylen-glycol-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Dipropylen glycol (DPG) \u2013 dung m\u00f4i, ch\u1ea5t gi\u1eef \u1ea9m, h\u00f3a d\u1ebbo keo d\u00e1n mi\u1ebfng d\u00e1n Dipropylen glycol (DPG) l\u00e0 ch\u1ea5t l\u1ecfng kh\u00f4ng m\u00e0u, g\u1ea7n nh\u01b0 kh\u00f4ng m\u00f9i, s\u1ea3n ph\u1ea9m ph\u1ee5 c\u1ee7a qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t propylen glycol. Trong b\u00e0o ch\u1ebf, DPG \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m dung m\u00f4i, ch\u1ea5t gi\u1eef \u1ea9m, ch\u1ea5t h\u00f3a d\u1ebbo v\u00e0 th\u00e0nh ph\u1ea7n&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3549","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3549"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3549\/revisions"}],"predecessor-version":[{"id":3809,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3549\/revisions\/3809"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3548"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3549"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3549"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3549"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}