{"id":3537,"date":"2026-09-29T08:36:49","date_gmt":"2026-09-29T01:36:49","guid":{"rendered":"https:\/\/cpc1.vn\/decyl-oleat\/"},"modified":"2026-09-29T08:36:49","modified_gmt":"2026-09-29T01:36:49","slug":"decyl-oleat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/decyl-oleat\/","title":{"rendered":"Decyl oleat \u2013 ch\u1ea5t l\u00e0m m\u1ec1m, t\u00e1 d\u01b0\u1ee3c d\u1ea7u cho kem v\u00e0 lotion"},"content":{"rendered":"

Decyl oleat \u2013 ch\u1ea5t l\u00e0m m\u1ec1m, t\u00e1 d\u01b0\u1ee3c d\u1ea7u cho kem v\u00e0 lotion<\/h1>\n

Decyl oleat<\/strong> l\u00e0 ester c\u1ee7a alcol decylic v\u1edbi acid b\u00e9o, ch\u1ee7 y\u1ebfu acid oleic; d\u1ea1ng l\u1ecfng trong, kh\u00f4ng m\u00e0u ho\u1eb7c v\u00e0ng nh\u1ea1t, \u0111\u1ed9 nh\u1edbt th\u1ea5p. Trong b\u00e0o ch\u1ebf, decyl oleat l\u00e0 ch\u1ea5t l\u00e0m m\u1ec1m (emollient)<\/strong> v\u00e0 t\u00e1 d\u01b0\u1ee3c d\u1ea7u<\/strong> cho kem, lotion v\u00e0 s\u1ea3n ph\u1ea9m ch\u0103m s\u00f3c da.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nDecyl 9-octadecenoat, ester decyl c\u1ee7a acid oleic, decylis oleas<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n3687-46-5<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC28<\/sub>H54<\/sub>O2<\/sub> \u2013 422,74<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t l\u00e0m m\u1ec1m, t\u00e1 d\u01b0\u1ee3c d\u1ea7u<\/td>\n<\/tr>\n
D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nBP, Ph.Eur.; c\u00f3 ti\u00eau chu\u1ea9n trong JPE<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • Ch\u1ea5t l\u00e0m m\u1ec1m trong kem, lotion d\u01b0\u1ee3c d\u1ee5ng v\u00e0 s\u1ea3n ph\u1ea9m ch\u0103m s\u00f3c da, ch\u0103m s\u00f3c c\u00e1 nh\u00e2n.<\/li>\n
  • Ph\u1ed1i h\u1ee3p v\u1edbi s\u00e1p carnauba l\u00e0m h\u1ec7 bao g\u00f3i cho ch\u1ea5t ch\u1ed1ng n\u1eafng v\u00f4 c\u01a1.<\/li>\n
  • \u0110\u00e3 \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 l\u00e0m ch\u1ea5t t\u0103ng th\u1ea5m qua da (flurbiprofen), t\u00e1 d\u01b0\u1ee3c cho n\u1ec1n pha ch\u1ebf s\u1eb5n, vi nh\u0169 t\u01b0\u01a1ng v\u00e0 ch\u1ea5t mang lipid c\u1ea5u tr\u00fac nano (NLC).<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • BP \u0111\u1ecbnh ngh\u0129a decyl oleat l\u00e0 h\u1ed7n h\u1ee3p ester decyl c\u1ee7a c\u00e1c acid b\u00e9o, ch\u1ee7 y\u1ebfu acid oleic (cis-9-octadecenoic). Ch\u1ea5t l\u1ecfng trong, kh\u00f4ng m\u00e0u ho\u1eb7c v\u00e0ng nh\u1ea1t.<\/li>\n
    • T\u1ef7 tr\u1ecdng t\u01b0\u01a1ng \u0111\u1ed1i 0,86\u20130,87; ch\u1ec9 s\u1ed1 iod 55\u201370; ch\u1ec9 s\u1ed1 x\u00e0 ph\u00f2ng h\u00f3a 130\u2013140.<\/li>\n
    • \u0110i\u1ec3m s\u00f4i tr\u00ean 300 \u00b0C; \u0111i\u1ec3m ch\u1edbp ch\u00e1y 215 \u00b0C; chi\u1ebft su\u1ea5t 1,453\u20131,456; s\u1ee9c c\u0103ng b\u1ec1 m\u1eb7t kho\u1ea3ng 31 mN\/m.<\/li>\n
    • \u0110\u1ed9 nh\u1edbt kho\u1ea3ng 14\u201317 mPa\u00b7s \u1edf 25 \u00b0C.<\/li>\n
    • \u0110\u1ed9 tan: h\u1ea7u nh\u01b0 kh\u00f4ng tan trong n\u01b0\u1edbc; tr\u1ed9n l\u1eabn v\u1edbi ethanol 96%, methylen clorid, ether d\u1ea7u h\u1ecfa nh\u1eb9; tan trong isopropyl myristat v\u00e0 alcol oleylic.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ea3o qu\u1ea3n d\u01b0\u1edbi 30 \u00b0C, tr\u00e1nh \u1ea9m. Nh\u00e0 s\u1ea3n xu\u1ea5t th\u00eam h\u1ed7n h\u1ee3p tocopherol \u0111\u1ec3 ch\u1ed1ng t\u1ef1 oxy h\u00f3a. Ch\u1ec9 s\u1ed1 peroxyd c\u00f3 th\u1ec3 t\u0103ng t\u00f9y nhi\u1ec7t \u0111\u1ed9 b\u1ea3o qu\u1ea3n; ch\u1ea5t l\u01b0\u1ee3ng ch\u01b0a b\u1ecb \u1ea3nh h\u01b0\u1edfng khi ch\u1ec9 s\u1ed1 peroxyd c\u00f2n d\u01b0\u1edbi 8,0.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t oxy h\u00f3a m\u1ea1nh.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Ester h\u00f3a alcol decylic v\u1edbi acid oleic.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
        \n
      • D\u00f9ng trong m\u1ef9 ph\u1ea9m v\u00e0 ch\u1ebf ph\u1ea9m b\u00f4i, nh\u00ecn chung \u0111\u01b0\u1ee3c coi l\u00e0 kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng.<\/li>\n
      • Dung d\u1ecbch 15% trong d\u1ea7u ng\u00f4 h\u1ea7u nh\u01b0 kh\u00f4ng k\u00edch \u1ee9ng m\u1eaft th\u1ecf, kh\u00f4ng g\u00e2y m\u1eabn c\u1ea3m da chu\u1ed9t lang; dung d\u1ecbch 10% kh\u00f4ng k\u00edch \u1ee9ng da th\u1ecf. Th\u1eed \u00e1p da l\u1eb7p l\u1ea1i tr\u00ean ng\u01b0\u1eddi v\u1edbi 5,5% decyl oleat ch\u1ec9 c\u00f3 \u00edt ph\u1ea3n \u1ee9ng, \u0111i\u1ec3m k\u00edch \u1ee9ng th\u1ea5p.<\/li>\n
      • LD50<\/sub> (chu\u1ed9t c\u1ed1ng, u\u1ed1ng): 34,68 g\/kg (40 mL\/kg).<\/li>\n
      • Thao t\u00e1c theo l\u01b0u \u00fd th\u00f4ng th\u01b0\u1eddng.<\/li>\n<\/ul>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • C\u00f3 trong Canadian Natural Health Products Ingredients Database.<\/li>\n
        • C\u00f3 chuy\u00ean lu\u1eadn trong BP, Ph.Eur.<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan<\/h2>\n

          Isodecyl oleat<\/strong> (C28<\/sub>H54<\/sub>O2<\/sub>; CAS 59231-34-4): ch\u1ea5t l\u1ecfng tr\u1eafng t\u1edbi v\u00e0ng r\u01a1m, m\u00f9i \u0111\u1eb7c tr\u01b0ng; tan trong isopropyl myristat, d\u1ea7u l\u1ea1c, d\u1ea7u kho\u00e1ng, ethanol 95%, alcol oleylic; kh\u00f4ng tan trong n\u01b0\u1edbc, glycerin, propylen glycol. Kh\u00f4ng k\u00edch \u1ee9ng m\u1eaft, k\u00edch \u1ee9ng nh\u1eb9 da; LD50<\/sub> (chu\u1ed9t c\u1ed1ng, u\u1ed1ng) tr\u00ean 40 mL\/kg. D\u00f9ng l\u00e0m ch\u1ea5t l\u00e0m m\u1ec1m v\u00e0 dung m\u00f4i cho ch\u1ebf ph\u1ea9m b\u00f4i v\u00e0 m\u1ef9 ph\u1ea9m.<\/p>\n

          Xem th\u00eam ethyl oleat, acid oleic, alcol oleylic.<\/p>\n

          Ghi ch\u00fa:<\/strong> s\u1ed1 EINECS 222-981-6; PubChem CID 5363234.<\/p>\n

          Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

          N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Decyl Oleate<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

          \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

          L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          Decyl oleat \u2013 ch\u1ea5t l\u00e0m m\u1ec1m, t\u00e1 d\u01b0\u1ee3c d\u1ea7u cho kem v\u00e0 lotion Decyl oleat l\u00e0 ester c\u1ee7a alcol decylic v\u1edbi acid b\u00e9o, ch\u1ee7 y\u1ebfu acid oleic; d\u1ea1ng l\u1ecfng trong, kh\u00f4ng m\u00e0u ho\u1eb7c v\u00e0ng nh\u1ea1t, \u0111\u1ed9 nh\u1edbt th\u1ea5p. Trong b\u00e0o ch\u1ebf, decyl oleat l\u00e0 ch\u1ea5t l\u00e0m m\u1ec1m (emollient) v\u00e0 t\u00e1 d\u01b0\u1ee3c d\u1ea7u cho kem, lotion […]<\/p>\n","protected":false},"author":1,"featured_media":3536,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3537","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/decyl-oleat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/decyl-oleat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/decyl-oleat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/decyl-oleat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/decyl-oleat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/decyl-oleat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/decyl-oleat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/decyl-oleat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Decyl oleat \u2013 ch\u1ea5t l\u00e0m m\u1ec1m, t\u00e1 d\u01b0\u1ee3c d\u1ea7u cho kem v\u00e0 lotion Decyl oleat l\u00e0 ester c\u1ee7a alcol decylic v\u1edbi acid b\u00e9o, ch\u1ee7 y\u1ebfu acid oleic; d\u1ea1ng l\u1ecfng trong, kh\u00f4ng m\u00e0u ho\u1eb7c v\u00e0ng nh\u1ea1t, \u0111\u1ed9 nh\u1edbt th\u1ea5p. Trong b\u00e0o ch\u1ebf, decyl oleat l\u00e0 ch\u1ea5t l\u00e0m m\u1ec1m (emollient) v\u00e0 t\u00e1 d\u01b0\u1ee3c d\u1ea7u cho kem, lotion…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3537","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3537"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3537\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3536"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3537"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3537"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3537"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}