{"id":3420,"date":"2026-09-28T22:05:26","date_gmt":"2026-09-28T15:05:26","guid":{"rendered":"https:\/\/cpc1.vn\/amoni-clorid\/"},"modified":"2026-09-28T22:05:26","modified_gmt":"2026-09-28T15:05:26","slug":"amoni-clorid","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/amoni-clorid\/","title":{"rendered":"Amoni clorid (E510) \u2013 ch\u1ea5t acid h\u00f3a trong ch\u1ebf ph\u1ea9m u\u1ed1ng"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Amoni clorid (E510) \u2013 ch\u1ea5t acid h\u00f3a trong ch\u1ebf ph\u1ea9m u\u1ed1ng<\/h1>\n<p><strong>Amoni clorid<\/strong> (NH<sub>4<\/sub>Cl, E510, c\u00f2n g\u1ecdi sal ammoniac) l\u00e0 mu\u1ed1i v\u00f4 c\u01a1 d\u1ea1ng tinh th\u1ec3 kh\u00f4ng m\u00e0u, v\u1ecb m\u1eb7n m\u00e1t. Trong b\u00e0o ch\u1ebf, amoni clorid \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m <strong>ch\u1ea5t acid h\u00f3a<\/strong> trong ch\u1ebf ph\u1ea9m u\u1ed1ng v\u00e0 l\u00e0 ph\u1ee5 gia th\u1ef1c ph\u1ea9m.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean kh\u00e1c<\/td>\n<td>Ammonii chloridum, ammonium muriate, sal ammoniac, salmiac, E510<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>12125-02-9<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\n<td>NH<sub>4<\/sub>Cl \u2013 53,49<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\n<td>Ch\u1ea5t acid h\u00f3a<\/td>\n<\/tr>\n<tr>\n<td>D\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\n<td>BP, Ph.Eur., USP-NF<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Applications<\/h2>\n<ul>\n<li>Ch\u1ea5t acid h\u00f3a trong ch\u1ebf ph\u1ea9m u\u1ed1ng (siro, vi\u00ean n\u00e9n).<\/li>\n<li>Ph\u1ee5 gia th\u1ef1c ph\u1ea9m (E510).<\/li>\n<li>C\u00f3 m\u1eb7t trong m\u1ed9t s\u1ed1 thu\u1ed1c nh\u1ecf m\u1eaft v\u00e0 siro u\u1ed1ng l\u01b0u h\u00e0nh t\u1ea1i Anh.<\/li>\n<li>C\u00e1c c\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c c\u1ee7a amoni clorid n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft n\u00e0y.<\/li>\n<\/ul>\n<h2>M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>Tinh th\u1ec3 ho\u1eb7c kh\u1ed1i tinh th\u1ec3 kh\u00f4ng m\u00e0u, kh\u00f4ng m\u00f9i; ho\u1eb7c b\u1ed9t h\u1ea1t tr\u1eafng, v\u1ecb m\u1eb7n v\u00e0 m\u00e1t.<\/li>\n<li><strong>H\u00fat \u1ea9m, d\u1ec5 v\u00f3n c\u1ee5c.<\/strong><\/li>\n<li>Dung d\u1ecbch n\u01b0\u1edbc 5,5% c\u00f3 pH 4,5\u20135,5 (25 \u00b0C); t\u1ef7 tr\u1ecdng bi\u1ec3u ki\u1ebfn 0,6\u20130,9 g\/cm\u00b3; t\u1ef7 tr\u1ecdng ri\u00eang kho\u1ea3ng 1,53.<\/li>\n<li>Kh\u00f4ng n\u00f3ng ch\u1ea3y m\u00e0 th\u0103ng hoa; ph\u00e2n h\u1ee7y ho\u00e0n to\u00e0n \u1edf kho\u1ea3ng 338 \u00b0C. \u00c1p su\u1ea5t h\u01a1i 133,3 Pa (1 mmHg) \u1edf 160 \u00b0C.<\/li>\n<li>Tan trong n\u01b0\u1edbc (acid hydrocloric v\u00e0 natri clorid l\u00e0m gi\u1ea3m \u0111\u1ed9 tan); tan trong glycerin; h\u01a1i tan trong methanol v\u00e0 ethanol; h\u1ea7u nh\u01b0 kh\u00f4ng tan trong aceton, ether, ethyl acetat.<\/li>\n<li>Amoni clorid \u0111i qua \u0111\u01b0\u1ee3c m\u00e0ng h\u1ed3ng c\u1ea7u, n\u00ean dung d\u1ecbch d\u00f9 \u0111\u1eb3ng tr\u01b0\u01a1ng v\u1ec1 \u00e1p su\u1ea5t th\u1ea9m th\u1ea5u v\u1eabn g\u00e2y v\u1ee1 h\u1ed3ng c\u1ea7u nh\u01b0 m\u1ed9t dung d\u1ecbch nh\u01b0\u1ee3c tr\u01b0\u01a1ng \u2013 c\u1ea7n l\u01b0u \u00fd khi thi\u1ebft k\u1ebf ch\u1ebf ph\u1ea9m ti\u1ebfp x\u00fac m\u00e1u.<\/li>\n<\/ul>\n<h2>\u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n<p>B\u1ec1n v\u1ec1 m\u1eb7t h\u00f3a h\u1ecdc. \u1ede kho\u1ea3ng 338 \u00b0C ph\u00e2n h\u1ee7y ho\u00e0n to\u00e0n th\u00e0nh amoniac v\u00e0 hydro clorid. B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn kh\u00ed, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n<h2>T\u01b0\u01a1ng k\u1ef5<\/h2>\n<p>T\u01b0\u01a1ng k\u1ef5 v\u1edbi acid m\u1ea1nh v\u00e0 base m\u1ea1nh. Ph\u1ea3n \u1ee9ng m\u1ea1nh v\u1edbi amoni nitrat v\u00e0 kali clorat, c\u00f3 nguy c\u01a1 ch\u00e1y n\u1ed5. \u0102n m\u00f2n \u0111\u1ed3ng v\u00e0 h\u1ee3p ch\u1ea5t c\u1ee7a \u0111\u1ed3ng.<\/p>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>S\u1ea3n xu\u1ea5t c\u00f4ng nghi\u1ec7p b\u1eb1ng ph\u1ea3n \u1ee9ng gi\u1eefa amoniac v\u00e0 acid hydrocloric.<\/p>\n<h2>An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n<ul>\n<li>D\u00f9ng trong ch\u1ebf ph\u1ea9m u\u1ed1ng. D\u1ea1ng tinh khi\u1ebft \u0111\u1ed9c khi ti\u00eam d\u01b0\u1edbi da, t\u0129nh m\u1ea1ch, ti\u00eam b\u1eafp v\u00e0 \u0111\u1ed9c v\u1eeba ph\u1ea3i theo c\u00e1c \u0111\u01b0\u1eddng kh\u00e1c.<\/li>\n<li>H\u00edt ph\u1ea3i kh\u00f3i c\u00f3 th\u1ec3 g\u00e2y k\u00edch \u1ee9ng m\u1eaft, da, \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p (ho, kh\u00f3 th\u1edf, nh\u1ea1y c\u1ea3m ph\u1ed5i). Mu\u1ed1i amoni k\u00edch \u1ee9ng ni\u00eam m\u1ea1c d\u1ea1 d\u00e0y, c\u00f3 th\u1ec3 g\u00e2y bu\u1ed3n n\u00f4n, n\u00f4n.<\/li>\n<li>LD<sub>50<\/sub> (chu\u1ed9t nh\u1eaft, u\u1ed1ng): 1,3 g\/kg; (chu\u1ed9t c\u1ed1ng, u\u1ed1ng): 1,65 g\/kg; (chu\u1ed9t nh\u1eaft, ph\u00fac m\u1ea1c): 1,44 g\/kg.<\/li>\n<li>V\u1eadn chuy\u1ec3n, b\u1ea3o qu\u1ea3n xa nitrit v\u00e0 nitrat; \u0111\u1ec3 n\u01a1i kh\u00f4; n\u01b0\u1edbc th\u1ea3i c\u1ea7n x\u1eed l\u00fd tr\u01b0\u1edbc khi x\u1ea3. Khi \u0111un ph\u00e2n h\u1ee7y sinh kh\u00f3i \u0111\u1ed9c, k\u00edch \u1ee9ng (nit\u01a1 oxyd, amoniac, hydro clorid).<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n<ul>\n<li>GRAS; ph\u1ee5 gia th\u1ef1c ph\u1ea9m \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn t\u1ea1i ch\u00e2u \u00c2u (E510).<\/li>\n<li>C\u00f3 trong FDA Inactive Ingredients Database (siro v\u00e0 vi\u00ean n\u00e9n u\u1ed1ng); c\u00f3 trong thu\u1ed1c l\u01b0u h\u00e0nh t\u1ea1i Anh (thu\u1ed1c nh\u1ecf m\u1eaft, siro u\u1ed1ng); c\u00f3 trong danh m\u1ee5c th\u00e0nh ph\u1ea7n s\u1ea3n ph\u1ea9m s\u1ee9c kh\u1ecfe t\u1ef1 nhi\u00ean c\u1ee7a Canada.<\/li>\n<li>C\u00f3 chuy\u00ean lu\u1eadn trong BP, Ph.Eur., USP-NF; c\u00f3 ti\u00eau chu\u1ea9n trong Food Chemicals Codex.<\/li>\n<\/ul>\n<p><strong>Ch\u1ea5t li\u00ean quan:<\/strong> dung d\u1ecbch amoniac.<\/p>\n<p><strong>Ghi ch\u00fa:<\/strong> s\u1ed1 EINECS 235-186-4; PubChem CID 25517.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<p>N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn <em>Ammonium Chloride<\/em> trong: Sheskey P.J., Cook W.G., Cable C.G. (ch\u1ee7 bi\u00ean). <em>Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 8. Pharmaceutical Press (London) &amp; American Pharmacists Association (Washington DC), 2017. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n<p><em>\u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n<p><em>L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2017. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Amoni clorid (E510) \u2013 ch\u1ea5t acid h\u00f3a trong ch\u1ebf ph\u1ea9m u\u1ed1ng Amoni clorid (NH4Cl, E510, c\u00f2n g\u1ecdi sal ammoniac) l\u00e0 mu\u1ed1i v\u00f4 c\u01a1 d\u1ea1ng tinh th\u1ec3 kh\u00f4ng m\u00e0u, v\u1ecb m\u1eb7n m\u00e1t. Trong b\u00e0o ch\u1ebf, amoni clorid \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m ch\u1ea5t acid h\u00f3a trong ch\u1ebf ph\u1ea9m u\u1ed1ng v\u00e0 l\u00e0 ph\u1ee5 gia th\u1ef1c ph\u1ea9m. Th\u00f4ng tin nhanh [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3419,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-3420","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/amoni-clorid.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/amoni-clorid-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/amoni-clorid-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/amoni-clorid-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/amoni-clorid-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/amoni-clorid.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/amoni-clorid.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/amoni-clorid-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Amoni clorid (E510) \u2013 ch\u1ea5t acid h\u00f3a trong ch\u1ebf ph\u1ea9m u\u1ed1ng Amoni clorid (NH4Cl, E510, c\u00f2n g\u1ecdi sal ammoniac) l\u00e0 mu\u1ed1i v\u00f4 c\u01a1 d\u1ea1ng tinh th\u1ec3 kh\u00f4ng m\u00e0u, v\u1ecb m\u1eb7n m\u00e1t. Trong b\u00e0o ch\u1ebf, amoni clorid \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m ch\u1ea5t acid h\u00f3a trong ch\u1ebf ph\u1ea9m u\u1ed1ng v\u00e0 l\u00e0 ph\u1ee5 gia th\u1ef1c ph\u1ea9m. Th\u00f4ng tin nhanh&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3420","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=3420"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/3420\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/3419"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=3420"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=3420"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=3420"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}