{"id":2704,"date":"2026-09-27T21:11:09","date_gmt":"2026-09-27T14:11:09","guid":{"rendered":"https:\/\/cpc1.vn\/sap-cetyl-ester\/"},"modified":"2026-09-27T21:11:09","modified_gmt":"2026-09-27T14:11:09","slug":"sap-cetyl-ester","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/sap-cetyl-ester\/","title":{"rendered":"S\u00e1p cetyl ester \u2013 c\u00e1 voi t\u1ed5ng h\u1ee3p, ch\u1ea5t l\u00e0m m\u1ec1m v\u00e0 l\u00e0m c\u1ee9ng"},"content":{"rendered":"

S\u00e1p cetyl ester \u2013 c\u00e1 voi t\u1ed5ng h\u1ee3p, ch\u1ea5t l\u00e0m m\u1ec1m v\u00e0 l\u00e0m c\u1ee9ng<\/h1>\n

S\u00e1p cetyl ester<\/strong> (cetyl esters wax, \u201cs\u00e1p c\u00e1 voi t\u1ed5ng h\u1ee3p\u201d) l\u00e0 h\u1ed7n h\u1ee3p ch\u1ee7 y\u1ebfu c\u00e1c ester c\u1ee7a alcol b\u00e9o no C14\u2013C18 v\u1edbi acid b\u00e9o no C14\u2013C18. \u0110\u00e2y l\u00e0 ch\u1ea5t l\u00e0m c\u1ee9ng v\u00e0 ch\u1ea5t l\u00e0m m\u1ec1m (emollient)<\/strong> trong kem v\u00e0 thu\u1ed1c m\u1ee1, \u0111\u01b0\u1ee3c t\u1ea1o ra \u0111\u1ec3 thay th\u1ebf s\u00e1p c\u00e1 nh\u00e0 t\u00e1ng<\/strong> (spermaceti) t\u1ef1 nhi\u00ean.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nCera cetyla, synthetic spermaceti, spermaceti wax replacement; t\u00ean th\u01b0\u01a1ng m\u1ea1i: Crodamol SS, Cutina CP, Liponate SPS, Protachem MST, Ritaceti, Ritachol SS, Starfol Wax CG, Synaceti 116<\/td>\n<\/tr>\n
T\u00ean d\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nUSP-NF: Cetyl esters wax<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n977067-67-6<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 kh\u1ed1i l\u01b0\u1ee3ng ph\u00e2n t\u1eed<\/td>\nCn<\/sub>H2n<\/sub>O2<\/sub> v\u1edbi n = 26\u201338; kho\u1ea3ng 470\u2013490<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t l\u00e0m m\u1ec1m, ch\u1ea5t l\u00e0m c\u1ee9ng<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n\n\n\n\n\n\n\n\n
D\u1ea1ng d\u00f9ng<\/th>\nN\u1ed3ng \u0111\u1ed9 (%)<\/th>\n<\/tr>\n<\/thead>\n
Kem, thu\u1ed1c m\u1ee1 d\u00f9ng ngo\u00e0i<\/td>\n1\u201315<\/td>\n<\/tr>\n
Cold cream<\/td>\n12,5<\/td>\n<\/tr>\n
Thu\u1ed1c m\u1ee1 n\u01b0\u1edbc hoa h\u1ed3ng (rose water ointment)<\/td>\n12,5<\/td>\n<\/tr>\n
Thu\u1ed1c m\u1ee1 spermaceti<\/td>\n20,0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
    \n
  • L\u00e0m c\u1ee9ng v\u00e0 l\u00e0m m\u1ec1m trong kem, thu\u1ed1c m\u1ee1, thay s\u00e1p c\u00e1 nh\u00e0 t\u00e1ng t\u1ef1 nhi\u00ean.<\/li>\n
  • L\u00e0 ch\u1ea5t s\u01a1 n\u01b0\u1edbc, \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111\u1ec1 xu\u1ea5t l\u00e0m th\u00e0nh ph\u1ea7n cho n\u1ec1n matrix gelatin gi\u1ea3i ph\u00f3ng ki\u1ec3m so\u00e1t d\u00f9ng cho m\u1eaft.<\/li>\n<\/ul>\n

    L\u01b0u \u00fd: t\u00ednh ch\u1ea5t v\u1eadt l\u00fd kh\u00e1c nhau nhi\u1ec1u gi\u1eefa c\u00e1c nh\u00e0 s\u1ea3n xu\u1ea5t do kh\u00e1c h\u1ed7n h\u1ee3p ester, r\u00f5 nh\u1ea5t \u1edf nhi\u1ec7t \u0111\u1ed9 n\u00f3ng ch\u1ea3y \u2013 t\u1eeb 43\u201347 \u00b0C (kho\u1ea3ng USP-NF) \u0111\u1ebfn 51\u201355 \u00b0C. Lo\u1ea1i n\u00f3ng ch\u1ea3y cao ch\u1ee7 y\u1ebfu ch\u1ee9a cetyl palmitat v\u00e0 stearyl palmitat, v\u00e0 th\u01b0\u1eddng k\u00e9m tan h\u01a1n.<\/p>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • V\u1ea3y tr\u1eafng \u0111\u1ebfn tr\u1eafng ng\u00e0, h\u01a1i trong m\u1edd, c\u1ea5u tr\u00fac tinh th\u1ec3, \u00f3ng \u00e1nh ng\u1ecdc trai khi \u0111\u00f3ng b\u00e1nh; m\u00f9i th\u01a1m nh\u1eb9, v\u1ecb nh\u1ea1t.<\/li>\n
    • T\u1ef7 tr\u1ecdng 0,820\u20130,840 (50 \u00b0C); chi\u1ebft su\u1ea5t 1,440 (60 \u00b0C); \u0111\u1ed9 nh\u1edbt 6,7\u20137,4 mPa\u00b7s (100 \u00b0C); \u0111i\u1ec3m ch\u1edbp ch\u00e1y > 240 \u00b0C; ch\u1ec9 s\u1ed1 peroxid \u2264 0,5.<\/li>\n
    • \u0110\u1ed9 tan (20 \u00b0C): cloroform 1 trong 2,5; dicloromethan 1 trong 3; hexan 1 trong 8; d\u1ea7u kho\u00e1ng 1 trong 70; ethyl acetat 1 trong 80; ethanol 1 trong 170; aceton 1 trong 500; tan trong ether, d\u1ea7u b\u00e9o v\u00e0 tinh d\u1ea7u; th\u1ef1c t\u1ebf kh\u00f4ng tan trong n\u01b0\u1edbc v\u00e0 ethanol 95% l\u1ea1nh (tan 1 trong 2,5 \u1edf 78 \u00b0C).<\/li>\n
    • USP-NF: kho\u1ea3ng n\u00f3ng ch\u1ea3y 43\u201347 \u00b0C; ch\u1ec9 s\u1ed1 acid \u2264 5; ch\u1ec9 s\u1ed1 iod \u2264 1; ch\u1ec9 s\u1ed1 x\u00e0 ph\u00f2ng h\u00f3a 109\u2013120; th\u1eed parafin v\u00e0 acid t\u1ef1 do.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t; tr\u00e1nh nhi\u1ec7t \u0111\u1ed9 cao qu\u00e1 40 \u00b0C.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi acid m\u1ea1nh v\u00e0 base m\u1ea1nh.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Ester h\u00f3a tr\u1ef1c ti\u1ebfp h\u1ed7n h\u1ee3p alcol b\u00e9o v\u00e0 acid b\u00e9o ph\u00f9 h\u1ee3p.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
        \n
      • Ch\u1ea5t v\u00f4 h\u1ea1i, nh\u00ecn chung \u0111\u01b0\u1ee3c xem l\u00e0 v\u1ec1 c\u01a1 b\u1ea3n kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng.<\/li>\n
      • LD50<\/sub> (chu\u1ed9t c\u1ed1ng, u\u1ed1ng) > 16 g\/kg.<\/li>\n
      • Thao t\u00e1c theo bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba th\u00f4ng th\u01b0\u1eddng.<\/li>\n<\/ul>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • C\u00f3 trong FDA Inactive Ingredients Guide (ch\u1ebf ph\u1ea9m d\u00f9ng ngo\u00e0i); c\u00f3 trong thu\u1ed1c kh\u00f4ng ti\u00eam \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i Anh; c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n
        • C\u00f3 chuy\u00ean lu\u1eadn trong USP-NF.<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan: s\u00e1p c\u00e1 nh\u00e0 t\u00e1ng (spermaceti)<\/h2>\n

          S\u00e1p l\u1ea5y t\u1eeb \u0111\u1ea7u c\u00e1 nh\u00e0 t\u00e1ng (CAS 8002-23-1), g\u1ed3m ester cetyl c\u1ee7a acid b\u00e9o C12\u2013C18 \u2013 trong \u0111\u00f3 cetyl laurat, myristat, palmitat v\u00e0 stearat chi\u1ebfm \u00edt nh\u1ea5t 85%. Kh\u1ed1i tr\u1eafng, trong m\u1edd, h\u01a1i nh\u1eddn; n\u00f3ng ch\u1ea3y 44\u201352 \u00b0C; ch\u1ec9 s\u1ed1 x\u00e0 ph\u00f2ng h\u00f3a 120\u2013136; ch\u1ec9 s\u1ed1 iod 3,0\u20134,4; t\u1ef7 tr\u1ecdng 0,938\u20130,944. T\u1eebng d\u00f9ng trong kem, thu\u1ed1c m\u1ee1, thu\u1ed1c \u0111\u1ea1n nh\u01b0ng nay g\u1ea7n nh\u01b0 \u0111\u00e3 \u0111\u01b0\u1ee3c thay ho\u00e0n to\u00e0n b\u1eb1ng s\u00e1p cetyl ester t\u1ed5ng h\u1ee3p. (Ngo\u00e0i s\u00e1ch) Vi\u1ec7c khai th\u00e1c c\u00e1 voi th\u01b0\u01a1ng m\u1ea1i b\u1ecb c\u1ea5m theo l\u1ec7nh t\u1ea1m ho\u00e3n qu\u1ed1c t\u1ebf t\u1eeb n\u0103m 1986, n\u00ean ngu\u1ed3n spermaceti h\u1ea7u nh\u01b0 kh\u00f4ng c\u00f2n.<\/p>\n

          Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

          N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Wax, Cetyl Esters<\/em> trong:
          \nRowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5.
          \nPharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006.
          \nB\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

          \u1ea2nh minh h\u1ecda: thi\u1ebft k\u1ebf c\u1ee7a CPC1.<\/em><\/p>\n

          L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006.
          \nTi\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh
          \nhi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          S\u00e1p cetyl ester \u2013 c\u00e1 voi t\u1ed5ng h\u1ee3p, ch\u1ea5t l\u00e0m m\u1ec1m v\u00e0 l\u00e0m c\u1ee9ng S\u00e1p cetyl ester (cetyl esters wax, \u201cs\u00e1p c\u00e1 voi t\u1ed5ng h\u1ee3p\u201d) l\u00e0 h\u1ed7n h\u1ee3p ch\u1ee7 y\u1ebfu c\u00e1c ester c\u1ee7a alcol b\u00e9o no C14\u2013C18 v\u1edbi acid b\u00e9o no C14\u2013C18. \u0110\u00e2y l\u00e0 ch\u1ea5t l\u00e0m c\u1ee9ng v\u00e0 ch\u1ea5t l\u00e0m m\u1ec1m (emollient) trong kem v\u00e0 […]<\/p>","protected":false},"author":1,"featured_media":2703,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2704","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/sap-cetyl-ester.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/sap-cetyl-ester-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/sap-cetyl-ester-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/sap-cetyl-ester-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/sap-cetyl-ester-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/sap-cetyl-ester.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/sap-cetyl-ester.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/sap-cetyl-ester-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"S\u00e1p cetyl ester \u2013 c\u00e1 voi t\u1ed5ng h\u1ee3p, ch\u1ea5t l\u00e0m m\u1ec1m v\u00e0 l\u00e0m c\u1ee9ng S\u00e1p cetyl ester (cetyl esters wax, \u201cs\u00e1p c\u00e1 voi t\u1ed5ng h\u1ee3p\u201d) l\u00e0 h\u1ed7n h\u1ee3p ch\u1ee7 y\u1ebfu c\u00e1c ester c\u1ee7a alcol b\u00e9o no C14\u2013C18 v\u1edbi acid b\u00e9o no C14\u2013C18. \u0110\u00e2y l\u00e0 ch\u1ea5t l\u00e0m c\u1ee9ng v\u00e0 ch\u1ea5t l\u00e0m m\u1ec1m (emollient) trong kem v\u00e0…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2704","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2704"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2704\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2703"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2704"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2704"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2704"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}