{"id":2696,"date":"2026-09-27T21:05:15","date_gmt":"2026-09-27T14:05:15","guid":{"rendered":"https:\/\/cpc1.vn\/triethyl-citrat-tec\/"},"modified":"2026-09-29T12:16:16","modified_gmt":"2026-09-29T05:16:16","slug":"triethyl-citrat-tec","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/triethyl-citrat-tec\/","title":{"rendered":"Triethyl citrat (TEC) \u2013 ch\u1ea5t h\u00f3a d\u1ebbo th\u00f4ng d\u1ee5ng cho m\u00e0ng bao"},"content":{"rendered":"

Triethyl citrat (TEC) \u2013 ch\u1ea5t h\u00f3a d\u1ebbo th\u00f4ng d\u1ee5ng cho m\u00e0ng bao<\/h1>\n

Triethyl citrat<\/strong> (TEC, E1505) l\u00e0 triester c\u1ee7a acid citric v\u1edbi ethanol, c\u00f4ng th\u1ee9c C12<\/sub>H20<\/sub>O7<\/sub>. \u0110\u00e2y l\u00e0 m\u1ed9t trong nh\u1eefng ch\u1ea5t h\u00f3a d\u1ebbo<\/strong> ph\u1ed5 bi\u1ebfn nh\u1ea5t cho m\u00e0ng bao d\u01b0\u1ee3c ph\u1ea9m, \u0111\u1eb7c bi\u1ec7t trong h\u1ec7 bao ph\u00e2n t\u00e1n n\u01b0\u1edbc, v\u00e0 c\u0169ng l\u00e0 ph\u1ee5 gia th\u1ef1c ph\u1ea9m.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nTEC, citric acid ethyl ester, E1505; t\u00ean th\u01b0\u01a1ng m\u1ea1i: Citroflex 2, Citrofol AI, Hydagen CAT<\/td>\n<\/tr>\n
T\u00ean d\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nBP: Triethyl citrate; Ph.Eur.: Triethylis citras; USP-NF: Triethyl citrate<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n77-93-0<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 kh\u1ed1i l\u01b0\u1ee3ng ph\u00e2n t\u1eed<\/td>\nC12<\/sub>H20<\/sub>O7<\/sub> \u2013 276,29<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t h\u00f3a d\u1ebbo<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • H\u00f3a d\u1ebbo polymer trong m\u00e0ng bao vi\u00ean n\u00e9n, nang, pellet v\u00e0 c\u1ed1m cho c\u00e1c m\u1ee5c \u0111\u00edch che v\u1ecb, gi\u1ea3i ph\u00f3ng ngay, gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i v\u00e0 bao tan trong ru\u1ed9t \u2013 c\u00f9ng nh\u00f3m v\u1edbi acetyltriethyl citrat, tributyl citrat, acetyltributyl citrat.<\/li>\n
  • (Ngo\u00e0i s\u00e1ch) R\u1ea5t hay d\u00f9ng v\u1edbi ph\u00e2n t\u00e1n n\u01b0\u1edbc polymethacrylat, ethylcellulose, cellulose acetat phthalat, HPMC; l\u01b0\u1ee3ng d\u00f9ng th\u01b0\u1eddng kho\u1ea3ng 10\u201325% so v\u1edbi kh\u1ed1i l\u01b0\u1ee3ng polymer. V\u00ec tan \u0111\u01b0\u1ee3c trong n\u01b0\u1edbc (1 trong 15), TEC l\u00e0 ch\u1ea5t h\u00f3a d\u1ebbo t\u01b0\u01a1ng \u0111\u1ed1i th\u00e2n n\u01b0\u1edbc, tr\u1ed9n v\u00e0o h\u1ec7 ph\u00e2n t\u00e1n n\u01b0\u1edbc nhanh h\u01a1n c\u00e1c ester butyl.<\/li>\n
  • Ph\u1ee5 gia th\u1ef1c ph\u1ea9m tr\u1ef1c ti\u1ebfp: t\u1ea1o h\u01b0\u01a1ng, dung m\u00f4i, ch\u1ea5t di\u1ec7n ho\u1ea1t.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Ch\u1ea5t l\u1ecfng d\u1ea1ng d\u1ea7u, trong, kh\u00f4ng m\u00f9i, g\u1ea7n nh\u01b0 kh\u00f4ng m\u00e0u.<\/li>\n
    • \u0110\u1ed9 nh\u1edbt 35,2 mPa\u00b7s (25 \u00b0C); \u0111i\u1ec3m \u0111\u00f4ng ch\u1ea3y \u221245 \u00b0C; s\u00f4i 288 \u00b0C (k\u00e8m ph\u00e2n h\u1ee7y); \u0111i\u1ec3m ch\u1edbp ch\u00e1y 155 \u00b0C; ch\u1ec9 s\u1ed1 acid 0,02.<\/li>\n
    • Tan trong n\u01b0\u1edbc (1 trong 15) v\u00e0 d\u1ea7u l\u1ea1c (1 trong 125); tr\u1ed9n l\u1eabn v\u1edbi ethanol 95%, aceton, propan-2-ol.<\/li>\n
    • D\u01b0\u1ee3c \u0111i\u1ec3n: \u0111\u1ecbnh l\u01b0\u1ee3ng 98,5\u2013101,0% (Ph.Eur.) ho\u1eb7c 99,0\u2013100,5% (USP-NF) tr\u00ean ch\u1ebf ph\u1ea9m khan; n\u01b0\u1edbc \u2264 0,25%; chi\u1ebft su\u1ea5t 1,440\u20131,446 (Ph.Eur.) \/ 1,439\u20131,441 (USP-NF); t\u1ef7 tr\u1ecdng 1,135\u20131,139 (USP-NF).<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      \u1ed4n \u0111\u1ecbnh khi b\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi ki\u1ec1m m\u1ea1nh v\u00e0 ch\u1ea5t oxy h\u00f3a.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Ester h\u00f3a acid citric v\u1edbi ethanol c\u00f3 x\u00fac t\u00e1c.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
        \n
      • D\u00f9ng trong thu\u1ed1c u\u1ed1ng v\u00e0 l\u00e0m ph\u1ee5 gia th\u1ef1c ph\u1ea9m tr\u1ef1c ti\u1ebfp; nh\u00ecn chung \u0111\u01b0\u1ee3c xem l\u00e0 kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng; tuy nhi\u00ean u\u1ed1ng l\u01b0\u1ee3ng l\u1edbn c\u00f3 th\u1ec3 c\u00f3 h\u1ea1i.<\/li>\n
      • LD50<\/sub> (chu\u1ed9t c\u1ed1ng, u\u1ed1ng): 5,9 g\/kg; (chu\u1ed9t c\u1ed1ng, d\u01b0\u1edbi da): 6,6 g\/kg; (chu\u1ed9t c\u1ed1ng, m\u00e0ng b\u1ee5ng): 4 g\/kg; (chu\u1ed9t nh\u1eaft, m\u00e0ng b\u1ee5ng): 1,75 g\/kg.<\/li>\n
      • K\u00edch \u1ee9ng m\u1eaft, c\u00f3 th\u1ec3 k\u00edch \u1ee9ng da; d\u1ea1ng s\u01b0\u01a1ng ho\u1eb7c \u1edf nhi\u1ec7t \u0111\u1ed9 cao k\u00edch \u1ee9ng h\u00f4 h\u1ea5p. D\u00f9ng g\u0103ng tay, k\u00ednh b\u1ea3o h\u1ed9 v\u00e0 m\u1eb7t n\u1ea1 ph\u00f2ng \u0111\u1ed9c.<\/li>\n<\/ul>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • GRAS t\u1ea1i M\u1ef9; ph\u1ee5 gia th\u1ef1c ph\u1ea9m \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn t\u1ea1i ch\u00e2u \u00c2u (E1505).<\/li>\n
        • C\u00f3 trong FDA Inactive Ingredients Guide (nang, vi\u00ean n\u00e9n u\u1ed1ng); c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n
        • C\u00f3 chuy\u00ean lu\u1eadn trong BP, Ph.Eur. v\u00e0 USP-NF; c\u00f3 ti\u00eau chu\u1ea9n trong Food Chemicals Codex.<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan:<\/strong> acetyltributyl citrat, acetyltriethyl citrat, tributyl citrat.<\/p>\n

          Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

          N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Triethyl Citrate<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

          \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

          L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          Triethyl citrat (TEC) \u2013 ch\u1ea5t h\u00f3a d\u1ebbo th\u00f4ng d\u1ee5ng cho m\u00e0ng bao Triethyl citrat (TEC, E1505) l\u00e0 triester c\u1ee7a acid citric v\u1edbi ethanol, c\u00f4ng th\u1ee9c C12H20O7. \u0110\u00e2y l\u00e0 m\u1ed9t trong nh\u1eefng ch\u1ea5t h\u00f3a d\u1ebbo ph\u1ed5 bi\u1ebfn nh\u1ea5t cho m\u00e0ng bao d\u01b0\u1ee3c ph\u1ea9m, \u0111\u1eb7c bi\u1ec7t trong h\u1ec7 bao ph\u00e2n t\u00e1n n\u01b0\u1edbc, v\u00e0 c\u0169ng l\u00e0 ph\u1ee5 gia […]<\/p>\n","protected":false},"author":1,"featured_media":2695,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2696","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triethyl-citrat-tec.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triethyl-citrat-tec-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triethyl-citrat-tec-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triethyl-citrat-tec-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triethyl-citrat-tec-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triethyl-citrat-tec.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triethyl-citrat-tec.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triethyl-citrat-tec-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Triethyl citrat (TEC) \u2013 ch\u1ea5t h\u00f3a d\u1ebbo th\u00f4ng d\u1ee5ng cho m\u00e0ng bao Triethyl citrat (TEC, E1505) l\u00e0 triester c\u1ee7a acid citric v\u1edbi ethanol, c\u00f4ng th\u1ee9c C12H20O7. \u0110\u00e2y l\u00e0 m\u1ed9t trong nh\u1eefng ch\u1ea5t h\u00f3a d\u1ebbo ph\u1ed5 bi\u1ebfn nh\u1ea5t cho m\u00e0ng bao d\u01b0\u1ee3c ph\u1ea9m, \u0111\u1eb7c bi\u1ec7t trong h\u1ec7 bao ph\u00e2n t\u00e1n n\u01b0\u1edbc, v\u00e0 c\u0169ng l\u00e0 ph\u1ee5 gia…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2696","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2696"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2696\/revisions"}],"predecessor-version":[{"id":3978,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2696\/revisions\/3978"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2695"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2696"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2696"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2696"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}