{"id":2690,"date":"2026-09-27T21:04:50","date_gmt":"2026-09-27T14:04:50","guid":{"rendered":"https:\/\/cpc1.vn\/triacetin\/"},"modified":"2026-09-29T12:15:49","modified_gmt":"2026-09-29T05:15:49","slug":"triacetin","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/triacetin\/","title":{"rendered":"Triacetin \u2013 ch\u1ea5t h\u00f3a d\u1ebbo th\u00e2n n\u01b0\u1edbc cho m\u00e0ng bao, dung m\u00f4i"},"content":{"rendered":"

Triacetin \u2013 ch\u1ea5t h\u00f3a d\u1ebbo th\u00e2n n\u01b0\u1edbc cho m\u00e0ng bao, dung m\u00f4i<\/h1>\n

Triacetin<\/strong> (glycerol triacetat, E1518) l\u00e0 triester c\u1ee7a glycerin v\u1edbi acid acetic, c\u00f4ng th\u1ee9c C9<\/sub>H14<\/sub>O6<\/sub>. Trong b\u00e0o ch\u1ebf, triacetin ch\u1ee7 y\u1ebfu l\u00e0 ch\u1ea5t h\u00f3a d\u1ebbo th\u00e2n n\u01b0\u1edbc<\/strong> cho m\u00e0ng bao polymer; ngo\u00e0i ra d\u00f9ng l\u00e0m dung m\u00f4i, ch\u1ea5t gi\u1eef \u1ea9m v\u00e0 ch\u1ea5t \u0111\u1ecbnh h\u01b0\u01a1ng.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nGlycerol triacetate, glyceryl triacetate, triacetyl glycerine, E1518, Captex 500<\/td>\n<\/tr>\n
T\u00ean d\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nBP, USP: Triacetin; Ph.Eur.: Glycerolum triacetas<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n102-76-1<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 kh\u1ed1i l\u01b0\u1ee3ng ph\u00e2n t\u1eed<\/td>\nC9<\/sub>H14<\/sub>O6<\/sub> \u2013 218,21<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t gi\u1eef \u1ea9m, ch\u1ea5t h\u00f3a d\u1ebbo, dung m\u00f4i<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • Ch\u1ea5t h\u00f3a d\u1ebbo th\u00e2n n\u01b0\u1edbc<\/strong> trong bao m\u00e0ng polymer h\u1ec7 n\u01b0\u1edbc l\u1eabn h\u1ec7 dung m\u00f4i cho vi\u00ean n\u00e9n, nang, pellet (h\u1ea1t tr\u00f2n) v\u00e0 c\u1ed1m; n\u1ed3ng \u0111\u1ed9 th\u01b0\u1eddng 10\u201335% (kl\/kl so v\u1edbi polymer). Hay d\u00f9ng v\u1edbi cellulose acetat, HPMC, polymethacrylat.<\/li>\n
  • Dung m\u00f4i, ch\u1ea5t \u0111\u1ecbnh h\u01b0\u01a1ng (gi\u1eef m\u00f9i) trong m\u1ef9 ph\u1ea9m, n\u01b0\u1edbc hoa v\u00e0 th\u1ef1c ph\u1ea9m.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Ch\u1ea5t l\u1ecfng s\u00e1nh, kh\u00f4ng m\u00e0u, m\u00f9i h\u01a1i b\u00e9o.<\/li>\n
    • T\u1ef7 tr\u1ecdng 1,16 g\/cm\u00b3 (25 \u00b0C); chi\u1ebft su\u1ea5t 1,4296 (25 \u00b0C); s\u00f4i 258 \u00b0C.<\/li>\n
    • \u0110\u00f4ng \u0111\u1eb7c \u1edf 3,2 \u00b0C nh\u01b0ng d\u1ec5 ch\u1eadm \u0111\u00f4ng \u0111\u1ebfn kho\u1ea3ng \u221270 \u00b0C.<\/li>\n
    • \u0110\u1ed9 nh\u1edbt gi\u1ea3m m\u1ea1nh theo nhi\u1ec7t \u0111\u1ed9: kho\u1ea3ng 107 mPa\u00b7s (0 \u00b0C), 17,4 mPa\u00b7s (25 \u00b0C), 1,8 mPa\u00b7s (100 \u00b0C).<\/li>\n
    • Tan trong n\u01b0\u1edbc kho\u1ea3ng 1 trong 14 (20 \u00b0C); tr\u1ed9n l\u1eabn v\u1edbi ethanol, cloroform, ether, toluen, carbon disulfid.<\/li>\n
    • \u0110i\u1ec3m ch\u1edbp ch\u00e1y 153 \u00b0C (c\u1ed1c h\u1edf); nhi\u1ec7t \u0111\u1ed9 t\u1ef1 b\u1ed1c ch\u00e1y 432 \u00b0C; \u00e1p su\u1ea5t h\u01a1i 133 Pa (100 \u00b0C).<\/li>\n
    • D\u01b0\u1ee3c \u0111i\u1ec3n (Ph.Eur., USP): \u0111\u1ecbnh l\u01b0\u1ee3ng 97,0\u2013100,5% (khan); n\u01b0\u1edbc \u2264 0,2%; t\u1ef7 tr\u1ecdng 1,159\u20131,164 (Ph.Eur.) ho\u1eb7c 1,152\u20131,158 (USP); chi\u1ebft su\u1ea5t 1,429\u20131,432.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      \u1ed4n \u0111\u1ecbnh. B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, kh\u00f4ng b\u1eb1ng kim lo\u1ea1i<\/strong>, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi kim lo\u1ea1i; c\u00f3 th\u1ec3 ph\u1ea3n \u1ee9ng v\u1edbi ch\u1ea5t oxy h\u00f3a; c\u00f3 th\u1ec3 l\u00e0m h\u1ecfng v\u1ea3i rayon.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Ester h\u00f3a glycerin b\u1eb1ng anhydrid acetic.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
        \n
      • D\u00f9ng trong thu\u1ed1c u\u1ed1ng; \u1edf m\u1ee9c d\u00f9ng l\u00e0m t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c xem l\u00e0 t\u01b0\u01a1ng \u0111\u1ed1i kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng.<\/li>\n
      • LD50<\/sub> (u\u1ed1ng): chu\u1ed9t c\u1ed1ng 3 g\/kg, chu\u1ed9t nh\u1eaft 1,1 g\/kg; (t\u0129nh m\u1ea1ch): ch\u00f3 1,5 g\/kg, chu\u1ed9t nh\u1eaft 1,6 g\/kg, th\u1ecf 0,75 g\/kg.<\/li>\n
      • C\u00f3 th\u1ec3 k\u00edch \u1ee9ng m\u1eaft; d\u00f9ng k\u00ednh b\u1ea3o h\u1ed9 v\u00e0 g\u0103ng tay.<\/li>\n<\/ul>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • GRAS t\u1ea1i M\u1ef9; ph\u1ee5 gia th\u1ef1c ph\u1ea9m \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn t\u1ea1i ch\u00e2u \u00c2u cho m\u1ed9t s\u1ed1 \u1ee9ng d\u1ee5ng (E1518).<\/li>\n
        • C\u00f3 trong FDA Inactive Ingredients Guide (nang, vi\u00ean n\u00e9n, gel u\u1ed1ng); c\u00f3 trong thu\u1ed1c kh\u00f4ng d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i Anh; c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n
        • C\u00f3 chuy\u00ean lu\u1eadn trong BP, Ph.Eur. v\u00e0 USP; c\u00f3 ti\u00eau chu\u1ea9n trong Food Chemicals Codex.<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan:<\/strong> s\u00e1ch kh\u00f4ng n\u00eau; c\u00e1c ch\u1ea5t h\u00f3a d\u1ebbo c\u00f9ng nh\u00f3m: triethyl citrat, tributyl citrat, acetyltriethyl citrat, dibutyl sebacat, diethyl phthalat.<\/p>\n

          Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

          N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Triacetin<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

          \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

          L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          Triacetin \u2013 ch\u1ea5t h\u00f3a d\u1ebbo th\u00e2n n\u01b0\u1edbc cho m\u00e0ng bao, dung m\u00f4i Triacetin (glycerol triacetat, E1518) l\u00e0 triester c\u1ee7a glycerin v\u1edbi acid acetic, c\u00f4ng th\u1ee9c C9H14O6. Trong b\u00e0o ch\u1ebf, triacetin ch\u1ee7 y\u1ebfu l\u00e0 ch\u1ea5t h\u00f3a d\u1ebbo th\u00e2n n\u01b0\u1edbc cho m\u00e0ng bao polymer; ngo\u00e0i ra d\u00f9ng l\u00e0m dung m\u00f4i, ch\u1ea5t gi\u1eef \u1ea9m v\u00e0 ch\u1ea5t \u0111\u1ecbnh h\u01b0\u01a1ng. […]<\/p>\n","protected":false},"author":1,"featured_media":2689,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2690","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triacetin.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triacetin-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triacetin-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triacetin-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triacetin-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triacetin.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triacetin.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/triacetin-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Triacetin \u2013 ch\u1ea5t h\u00f3a d\u1ebbo th\u00e2n n\u01b0\u1edbc cho m\u00e0ng bao, dung m\u00f4i Triacetin (glycerol triacetat, E1518) l\u00e0 triester c\u1ee7a glycerin v\u1edbi acid acetic, c\u00f4ng th\u1ee9c C9H14O6. Trong b\u00e0o ch\u1ebf, triacetin ch\u1ee7 y\u1ebfu l\u00e0 ch\u1ea5t h\u00f3a d\u1ebbo th\u00e2n n\u01b0\u1edbc cho m\u00e0ng bao polymer; ngo\u00e0i ra d\u00f9ng l\u00e0m dung m\u00f4i, ch\u1ea5t gi\u1eef \u1ea9m v\u00e0 ch\u1ea5t \u0111\u1ecbnh h\u01b0\u01a1ng.…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2690","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2690"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2690\/revisions"}],"predecessor-version":[{"id":3973,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2690\/revisions\/3973"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2689"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2690"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2690"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2690"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}