{"id":2680,"date":"2026-09-27T20:59:21","date_gmt":"2026-09-27T13:59:21","guid":{"rendered":"https:\/\/cpc1.vn\/thiomersal\/"},"modified":"2026-09-28T21:26:27","modified_gmt":"2026-09-28T14:26:27","slug":"thiomersal","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/thiomersal\/","title":{"rendered":"Thiomersal (thimerosal) \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n th\u1ee7y ng\u00e2n h\u1eefu c\u01a1"},"content":{"rendered":"

Thiomersal (thimerosal) \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n th\u1ee7y ng\u00e2n h\u1eefu c\u01a1<\/h1>\n

Thiomersal<\/strong> (thimerosal, natri ethylmercurithiosalicylat) l\u00e0 h\u1ee3p ch\u1ea5t th\u1ee7y ng\u00e2n h\u1eefu c\u01a1, c\u00f4ng th\u1ee9c C9<\/sub>H9<\/sub>HgNaO2<\/sub>S, d\u00f9ng l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n<\/strong> trong ch\u1ebf ph\u1ea9m sinh h\u1ecdc v\u00e0 d\u01b0\u1ee3c ph\u1ea9m t\u1eeb nh\u1eefng n\u0103m 1930 \u2013 \u0111\u1eb7c bi\u1ec7t trong thu\u1ed1c ti\u00eam, v\u1eafc xin, thu\u1ed1c nh\u1ecf m\u1eaft. Do lo ng\u1ea1i v\u1ec1 \u0111\u1ed9c t\u00ednh c\u1ee7a th\u1ee7y ng\u00e2n v\u00e0 ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn, vi\u1ec7c s\u1eed d\u1ee5ng \u0111ang ng\u00e0y c\u00e0ng b\u1ecb h\u1ea1n ch\u1ebf.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nThimerosal, thiomersalate, mercurothiolate, sodium ethylmercurithiosalicylate, ethyl(sodium o-mercaptobenzoato)mercury<\/td>\n<\/tr>\n
T\u00ean d\u01b0\u1ee3c \u0111i\u1ec3n<\/td>\nBP: Thiomersal; Ph.Eur.: Thiomersalum; USP: Thimerosal<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n54-64-8<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 kh\u1ed1i l\u01b0\u1ee3ng ph\u00e2n t\u1eed<\/td>\nC9<\/sub>H9<\/sub>HgNaO2<\/sub>S \u2013 404,81<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n, ch\u1ea5t s\u00e1t khu\u1ea9n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n

D\u00f9ng thay benzalkonium clorid v\u00e0 c\u00e1c ch\u1ea5t b\u1ea3o qu\u1ea3n phenylth\u1ee7y ng\u00e2n; c\u00f3 t\u00e1c d\u1ee5ng k\u00ecm khu\u1ea9n v\u00e0 k\u00ecm n\u1ea5m. Ngo\u00e0i d\u01b0\u1ee3c ph\u1ea9m c\u00f2n d\u00f9ng trong m\u1ef9 ph\u1ea9m v\u00e0 dung d\u1ecbch b\u1ea3o qu\u1ea3n k\u00ednh \u00e1p tr\u00f2ng m\u1ec1m. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c s\u00e1t khu\u1ea9n t\u1ea1i ch\u1ed7 n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/p>\n\n\n\n\n\n\n\n\n\n
D\u1ea1ng d\u00f9ng<\/th>\nN\u1ed3ng \u0111\u1ed9 (%)<\/th>\n<\/tr>\n<\/thead>\n
Thu\u1ed1c ti\u00eam b\u1eafp, t\u0129nh m\u1ea1ch, d\u01b0\u1edbi da<\/td>\n0,01<\/td>\n<\/tr>\n
Dung d\u1ecbch nh\u1ecf m\u1eaft<\/td>\n0,001\u20130,15<\/td>\n<\/tr>\n
H\u1ed7n d\u1ecbch nh\u1ecf m\u1eaft<\/td>\n0,001\u20130,004<\/td>\n<\/tr>\n
Ch\u1ebf ph\u1ea9m nh\u1ecf tai<\/td>\n0,001\u20130,01<\/td>\n<\/tr>\n
Ch\u1ebf ph\u1ea9m d\u00f9ng ngo\u00e0i<\/td>\n0,01<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
    \n
  • B\u1ed9t k\u1ebft tinh m\u00e0u kem nh\u1ea1t, m\u00f9i nh\u1eb9 \u0111\u1eb7c tr\u01b0ng.<\/li>\n
  • pH dung d\u1ecbch 1% kl\/tt \u2248 6,7 (20 \u00b0C); pKa = 3,05 (25 \u00b0C); n\u00f3ng ch\u1ea3y k\u00e8m ph\u00e2n h\u1ee7y \u1edf 232\u2013233 \u00b0C.<\/li>\n
  • R\u1ea5t d\u1ec5 tan trong n\u01b0\u1edbc (1 trong 1), tan trong ethanol 95% (1 trong 8); th\u1ef1c t\u1ebf kh\u00f4ng tan trong benzen, ether.<\/li>\n
  • Ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n: c\u00f3 t\u00e1c d\u1ee5ng s\u00e1t khu\u1ea9n \u1edf pH acid; k\u00ecm khu\u1ea9n v\u00e0 k\u00ecm n\u1ea5m \u1edf pH trung t\u00ednh ho\u1eb7c ki\u1ec1m; kh\u00f4ng hi\u1ec7u qu\u1ea3 v\u1edbi vi sinh v\u1eadt t\u1ea1o b\u00e0o t\u1eed. N\u1ed3ng \u0111\u1ed9 \u1ee9c ch\u1ebf t\u1ed1i thi\u1ec3u (MIC) \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o: Staphylococcus aureus<\/em> 0,2 \u00b5g\/mL; E. coli<\/em>, Klebsiella pneumoniae<\/em>, Pseudomonas fluorescens<\/em> 4 \u00b5g\/mL; Pseudomonas aeruginosa<\/em>, P. cepacia<\/em> 8 \u00b5g\/mL; Candida albicans<\/em> 32 \u00b5g\/mL; Aspergillus niger<\/em>, Penicillium notatum<\/em> 128 \u00b5g\/mL.<\/li>\n
  • D\u01b0\u1ee3c \u0111i\u1ec3n (Ph.Eur., USP): \u0111\u1ecbnh l\u01b0\u1ee3ng 97,0\u2013101,0%; gi\u1edbi h\u1ea1n h\u1ee3p ch\u1ea5t th\u1ee7y ng\u00e2n v\u00f4 c\u01a1 \/ ion th\u1ee7y ng\u00e2n \u2264 0,70%; m\u1ea5t kh\u1ed1i l\u01b0\u1ee3ng khi l\u00e0m kh\u00f4 \u2264 0,5%.<\/li>\n<\/ul>\n

    \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n
      \n
    • \u1ed4n \u0111\u1ecbnh \u1edf nhi\u1ec7t \u0111\u1ed9 v\u00e0 \u00e1p su\u1ea5t th\u01b0\u1eddng; \u00e1nh s\u00e1ng c\u00f3 th\u1ec3 l\u00e0m \u0111\u1ed5i m\u00e0u.<\/li>\n
    • Dung d\u1ecbch n\u01b0\u1edbc ti\u1ec7t khu\u1ea9n \u0111\u01b0\u1ee3c b\u1eb1ng h\u1ea5p nhi\u1ec7t \u1ea9m nh\u01b0ng nh\u1ea1y s\u00e1ng. V\u1ebft \u0111\u1ed3ng v\u00e0 kim lo\u1ea1i kh\u00e1c l\u00e0m t\u0103ng t\u1ed1c \u0111\u1ed9 oxy h\u00f3a trong dung d\u1ecbch. C\u00f3 th\u1ec3 \u1ed5n \u0111\u1ecbnh b\u1eb1ng acid edetic\/edetat, nh\u01b0ng ch\u00fang l\u1ea1i l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 b\u1ea3o qu\u1ea3n.<\/li>\n
    • B\u1ea3o qu\u1ea3n nguy\u00ean li\u1ec7u trong bao b\u00ec k\u00edn, tr\u00e1nh \u00e1nh s\u00e1ng, n\u01a1i kh\u00f4 m\u00e1t.<\/li>\n<\/ul>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n
        \n
      • T\u01b0\u01a1ng k\u1ef5 v\u1edbi nh\u00f4m v\u00e0 kim lo\u1ea1i kh\u00e1c, ch\u1ea5t oxy h\u00f3a m\u1ea1nh, acid v\u00e0 base m\u1ea1nh, dung d\u1ecbch natri clorid, lecithin, h\u1ee3p ch\u1ea5t phenylth\u1ee7y ng\u00e2n, h\u1ee3p ch\u1ea5t amoni b\u1eadc b\u1ed1n, thioglycolat v\u00e0 protein.<\/li>\n
      • Natri metabisulfit, acid edetic v\u00e0 edetat trong dung d\u1ecbch c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u qu\u1ea3 b\u1ea3o qu\u1ea3n.<\/li>\n
      • Trong dung d\u1ecbch, thiomersal b\u1ecb h\u1ea5p ph\u1ee5 v\u00e0o bao b\u00ec nh\u1ef1a, nh\u1ea5t l\u00e0 polyethylen, v\u00e0 b\u1ecb h\u1ea5p ph\u1ee5 m\u1ea1nh v\u00e0o n\u00fat cao su (\u0111\u00e3 hay ch\u01b0a x\u1eed l\u00fd) ti\u1ebfp x\u00fac v\u1edbi dung d\u1ecbch \u2013 c\u1ea7n t\u00ednh \u0111\u1ebfn khi ch\u1ecdn bao b\u00ec v\u00e0 ki\u1ec3m tra h\u00e0m l\u01b0\u1ee3ng ch\u1ea5t b\u1ea3o qu\u1ea3n trong nghi\u00ean c\u1ee9u \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh.<\/li>\n
      • C\u00f3 b\u00e1o c\u00e1o hi\u1ec7u qu\u1ea3 gi\u1ea3m khi d\u00f9ng c\u00f9ng cyclodextrin, nh\u01b0ng nguy\u00ean nh\u00e2n li\u00ean quan \u0111\u1ebfn th\u00e0nh ph\u1ea7n lipid kh\u00e1c trong c\u00f4ng th\u1ee9c.<\/li>\n<\/ul>\n

        S\u1ea3n xu\u1ea5t<\/h2>\n

        Cho ethylth\u1ee7y ng\u00e2n clorid (ho\u1eb7c hydroxid) ph\u1ea3n \u1ee9ng v\u1edbi acid thiosalicylic v\u00e0 natri hydroxid trong ethanol 95%.<\/p>\n

        An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
          \n
        • Lo ng\u1ea1i ng\u00e0y c\u00e0ng t\u0103ng do hi\u1ec3u bi\u1ebft r\u00f5 h\u01a1n v\u1ec1 \u0111\u1ed9c t\u00ednh c\u1ee7a th\u1ee7y ng\u00e2n v\u00e0 c\u00e1c h\u1ee3p ch\u1ea5t th\u1ee7y ng\u00e2n, s\u1ed1 b\u00e1o c\u00e1o ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i (\u0111\u1eb7c bi\u1ec7t qu\u00e1 m\u1eabn) t\u0103ng v\u00e0 hi\u1ec7u qu\u1ea3 b\u1ea3o qu\u1ea3n b\u1ecb \u0111\u1eb7t c\u00e2u h\u1ecfi \u2013 \u0111\u00e3 c\u00f3 khuy\u1ebfn c\u00e1o kh\u00f4ng d\u00f9ng trong thu\u1ed1c nh\u1ecf m\u1eaft v\u00e0 v\u1eafc xin. C\u01a1 quan qu\u1ea3n l\u00fd ch\u00e2u \u00c2u v\u00e0 M\u1ef9 t\u1eebng khuy\u1ebfn ngh\u1ecb lo\u1ea1i d\u1ea7n thiomersal kh\u1ecfi v\u1eafc xin.<\/li>\n
        • C\u00e1c nghi\u00ean c\u1ee9u sau \u0111\u00f3 cho th\u1ea5y tuy c\u00f3 nguy c\u01a1 qu\u00e1 m\u1eabn, nguy c\u01a1 t\u1ed5n h\u1ea1i th\u1ea7n kinh \u1edf tr\u1ebb nh\u1ecf v\u1edbi l\u01b0\u1ee3ng thiomersal trong v\u1eafc xin l\u00e0 kh\u00f4ng \u0111\u00e1ng k\u1ec3; c\u00e1c c\u01a1 quan qu\u1ea3n l\u00fd c\u1eadp nh\u1eadt khuy\u1ebfn c\u00e1o: n\u00ean tr\u00e1nh thiomersal khi c\u00f3 th\u1ec3, nh\u01b0ng l\u1ee3i \u00edch c\u1ee7a v\u1eafc xin v\u01b0\u1ee3t xa nguy c\u01a1. C\u00e1c nghi\u00ean c\u1ee9u g\u1ea7n \u0111\u00e2y kh\u00f4ng th\u1ea5y li\u00ean h\u1ec7 gi\u1eefa ph\u01a1i nhi\u1ec5m thiomersal v\u00e0 t\u1ef1 k\u1ef7.<\/li>\n
        • Ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i hay g\u1eb7p nh\u1ea5t l\u00e0 qu\u00e1 m\u1eabn, th\u01b0\u1eddng l\u00e0 ban \u0111\u1ecf, s\u1ea9n ho\u1eb7c m\u1ee5n n\u01b0\u1edbc. Th\u1eed \u00e1p da cho th\u1ea5y dung d\u1ecbch 0,1% c\u00f3 th\u1ec3 g\u00e2y m\u1eabn c\u1ea3m \u1edf tr\u1ebb em; m\u1ed9t nghi\u00ean c\u1ee9u tr\u00ean 256 ng\u01b0\u1eddi kh\u1ecfe m\u1ea1nh c\u00f3 kho\u1ea3ng 6% d\u01b0\u01a1ng t\u00ednh. \u01af\u1edbc t\u00ednh kho\u1ea3ng 10% ng\u01b0\u1eddi \u0111eo k\u00ednh \u00e1p tr\u00f2ng nh\u1ea1y c\u1ea3m v\u1edbi thiomersal (\u0111\u1ecf m\u1eaft, k\u00edch \u1ee9ng, vi\u00eam k\u1ebft m\u1ea1c).<\/li>\n
        • C\u00f2n ghi nh\u1eadn: ph\u1ea3n \u1ee9ng d\u01b0\u01a1ng t\u00ednh gi\u1ea3 v\u1edbi tuberculin c\u0169, \u0111\u1ed9c t\u00ednh v\u1edbi tai, b\u1ecfng do dung d\u1ecbch 0,1% trong ethanol 50% sinh nhi\u1ec7t khi ti\u1ebfp x\u00fac \u0111i\u1ec7n c\u1ef1c l\u00e1 nh\u00f4m; k\u00edch \u1ee9ng m\u1eaft \u1edf ng\u01b0\u1eddi d\u00f9ng tetracyclin \u0111\u01b0\u1eddng u\u1ed1ng c\u00f9ng dung d\u1ecbch k\u00ednh \u00e1p tr\u00f2ng ch\u1ee9a thiomersal.<\/li>\n
        • LD50<\/sub> (chu\u1ed9t nh\u1eaft, u\u1ed1ng): 91 mg\/kg; (chu\u1ed9t c\u1ed1ng, u\u1ed1ng): 75 mg\/kg; (chu\u1ed9t c\u1ed1ng, d\u01b0\u1edbi da): 98 mg\/kg.<\/li>\n
        • K\u00edch \u1ee9ng da v\u00e0 ni\u00eam m\u1ea1c, c\u00f3 th\u1ec3 h\u1ea5p thu to\u00e0n th\u00e2n qua da v\u00e0 \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p tr\u00ean \u2013 thao t\u00e1c n\u01a1i th\u00f4ng gi\u00f3 t\u1ed1t, d\u00f9ng k\u00ednh, g\u0103ng tay v\u00e0 m\u1eb7t n\u1ea1 ph\u00f2ng \u0111\u1ed9c. Ph\u00e2n h\u1ee7y t\u1ea1o kh\u00f3i \u0111\u1ed9c ch\u1ee9a oxid carbon, l\u01b0u hu\u1ef3nh, th\u1ee7y ng\u00e2n v\u00e0 h\u01a1i th\u1ee7y ng\u00e2n. Gi\u1edbi h\u1ea1n ph\u01a1i nhi\u1ec5m ngh\u1ec1 nghi\u1ec7p t\u1ea1i Anh (h\u1ee3p ch\u1ea5t th\u1ee7y ng\u00e2n, t\u00ednh theo Hg): 0,01 mg\/m\u00b3 (8 gi\u1edd), 0,03 mg\/m\u00b3 (ng\u1eafn h\u1ea1n).<\/li>\n<\/ul>\n

          T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
            \n
          • C\u00f3 trong FDA Inactive Ingredients Guide (ti\u00eam b\u1eafp, t\u0129nh m\u1ea1ch, d\u01b0\u1edbi da; ch\u1ebf ph\u1ea9m nh\u1ecf m\u1eaft, nh\u1ecf tai, d\u00f9ng ngo\u00e0i); c\u00f3 trong thu\u1ed1c ti\u00eam v\u00e0 kh\u00f4ng ti\u00eam \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i Anh; c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n
          • M\u1ef9 ph\u1ea9m t\u1ea1i Anh: ch\u1ec9 \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n trong d\u1ea7u g\u1ed9i v\u00e0 kem t\u00f3c ch\u1ee9a ch\u1ea5t nh\u0169 h\u00f3a kh\u00f4ng ion (l\u00e0m m\u1ea5t t\u00e1c d\u1ee5ng c\u00e1c ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1c), t\u1ed1i \u0111a 0,003% t\u00ednh theo th\u1ee7y ng\u00e2n; t\u1ed5ng c\u00e1c h\u1ee3p ch\u1ea5t th\u1ee7y ng\u00e2n t\u1ed1i \u0111a 0,007%.<\/li>\n
          • C\u00f3 chuy\u00ean lu\u1eadn trong BP, Ph.Eur. v\u00e0 USP.<\/li>\n
          • (Ngo\u00e0i s\u00e1ch) C\u00f4ng \u01b0\u1edbc Minamata v\u1ec1 th\u1ee7y ng\u00e2n (hi\u1ec7u l\u1ef1c 2017) h\u1ea1n ch\u1ebf c\u00e1c s\u1ea3n ph\u1ea9m ch\u1ee9a th\u1ee7y ng\u00e2n nh\u01b0ng mi\u1ec5n tr\u1eeb thiomersal l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n trong v\u1eafc xin; nhi\u1ec1u v\u1eafc xin \u0111\u01a1n li\u1ec1u hi\u1ec7n \u0111\u00e3 kh\u00f4ng c\u00f2n thiomersal.<\/li>\n<\/ul>\n

            Ch\u1ea5t li\u00ean quan:<\/strong> phenylmercuric acetat, phenylmercuric borat, phenylmercuric nitrat.<\/p>\n

            Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

            N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Thimerosal<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

            \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

            L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

            Thiomersal (thimerosal) \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n th\u1ee7y ng\u00e2n h\u1eefu c\u01a1 Thiomersal (thimerosal, natri ethylmercurithiosalicylat) l\u00e0 h\u1ee3p ch\u1ea5t th\u1ee7y ng\u00e2n h\u1eefu c\u01a1, c\u00f4ng th\u1ee9c C9H9HgNaO2S, d\u00f9ng l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n trong ch\u1ebf ph\u1ea9m sinh h\u1ecdc v\u00e0 d\u01b0\u1ee3c ph\u1ea9m t\u1eeb nh\u1eefng n\u0103m 1930 \u2013 \u0111\u1eb7c bi\u1ec7t trong thu\u1ed1c ti\u00eam, v\u1eafc xin, thu\u1ed1c nh\u1ecf m\u1eaft. Do […]<\/p>\n","protected":false},"author":1,"featured_media":2679,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2680","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/thiomersal.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/thiomersal-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/thiomersal-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/thiomersal-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/thiomersal-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/thiomersal.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/thiomersal.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/thiomersal-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Thiomersal (thimerosal) \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n th\u1ee7y ng\u00e2n h\u1eefu c\u01a1 Thiomersal (thimerosal, natri ethylmercurithiosalicylat) l\u00e0 h\u1ee3p ch\u1ea5t th\u1ee7y ng\u00e2n h\u1eefu c\u01a1, c\u00f4ng th\u1ee9c C9H9HgNaO2S, d\u00f9ng l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n trong ch\u1ebf ph\u1ea9m sinh h\u1ecdc v\u00e0 d\u01b0\u1ee3c ph\u1ea9m t\u1eeb nh\u1eefng n\u0103m 1930 \u2013 \u0111\u1eb7c bi\u1ec7t trong thu\u1ed1c ti\u00eam, v\u1eafc xin, thu\u1ed1c nh\u1ecf m\u1eaft. Do…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2680","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2680"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2680\/revisions"}],"predecessor-version":[{"id":3384,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2680\/revisions\/3384"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2679"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2680"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2680"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2680"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}