Natri sulfit<\/strong> (natri sulfit khan, Na2<\/sub>SO3<\/sub>, E221) l\u00e0 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a<\/strong> d\u00f9ng t\u01b0\u01a1ng t\u1ef1 natri metabisulfit nh\u01b0ng cho ch\u1ebf ph\u1ea9m c\u00f3 pH cao<\/strong>; \u0111\u1ed3ng th\u1eddi l\u00e0 ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n hi\u1ec7u qu\u1ea3, nh\u1ea5t l\u00e0 v\u1edbi n\u1ea5m \u1edf pH th\u1ea5p (d\u00f9ng 0,1%).<\/p>\n Trong dung d\u1ecbch b\u1ecb oxy h\u00f2a tan oxy h\u00f3a ch\u1eadm th\u00e0nh sulfat; acid m\u1ea1nh t\u1ea1o acid sulfur\u01a1\/SO2<\/sub>; \u0111un n\u00f3ng ph\u00e2n h\u1ee7y t\u1ecfa oxid l\u01b0u hu\u1ef3nh. B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n T\u01b0\u01a1ng k\u1ef5 v\u1edbi acid, ch\u1ea5t oxy h\u00f3a, nhi\u1ec1u protein v\u00e0 vitamin B1 (thiamin). Xem th\u00eam t\u01b0\u01a1ng k\u1ef5 c\u1ee7a natri metabisulfit (epinephrin, cloramphenicol, cisplatin\u2026).<\/p>\n Cho kh\u00ed SO2<\/sub> ph\u1ea3n \u1ee9ng v\u1edbi dung d\u1ecbch NaOH t\u1ea1o natri bisulfit; trung h\u00f2a ti\u1ebfp b\u1eb1ng NaOH, gi\u1eef nhi\u1ec7t \u0111\u1ed9 tr\u00ean 33,6 \u00b0C \u0111\u1ec3 k\u1ebft tinh d\u1ea1ng khan (d\u01b0\u1edbi nhi\u1ec7t \u0111\u1ed9 n\u00e0y thu heptahydrat).<\/p>\n D\u00f9ng r\u1ed9ng r\u00e3i l\u00e0m ch\u1ea5t ch\u1ed1ng oxy h\u00f3a; n\u00f3i chung \u0111\u01b0\u1ee3c xem l\u00e0 t\u01b0\u01a1ng \u0111\u1ed1i kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng khi d\u00f9ng l\u00e0m t\u00e1 d\u01b0\u1ee3c, nh\u01b0ng \u0111\u00e3 c\u00f3 b\u00e1o c\u00e1o vi\u00eam da ti\u1ebfp x\u00fac v\u00e0 ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn (nh\u01b0 c\u00e1c sulfit kh\u00e1c, ng\u01b0\u1eddi hen c\u00f3 nguy c\u01a1 cao h\u01a1n). ADI nh\u00f3m sulfit (t\u00ednh theo SO2<\/sub>) theo JECFA: 0\u20130,7 mg\/kg (con s\u1ed1 in trong s\u00e1ch kh\u00f4ng th\u1ed1ng nh\u1ea5t). LD50<\/sub> (chu\u1ed9t nh\u1eaft, u\u1ed1ng): 0,820 g\/kg; (chu\u1ed9t c\u1ed1ng, t\u0129nh m\u1ea1ch): 0,115 g\/kg. Thao t\u00e1c theo bi\u1ec7n ph\u00e1p th\u00f4ng th\u01b0\u1eddng.<\/p>\n Ch\u1ea5t li\u00ean quan:<\/strong> natri sulfit heptahydrat, natri metabisulfit, natri bisulfit, kali metabisulfit.<\/p>\n N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Sodium Sulfite<\/em> trong: \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Natri sulfit (E221) \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a cho ch\u1ebf ph\u1ea9m pH ki\u1ec1m, b\u1ea3o qu\u1ea3n Natri sulfit (natri sulfit khan, Na2SO3, E221) l\u00e0 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a d\u00f9ng t\u01b0\u01a1ng t\u1ef1 natri metabisulfit nh\u01b0ng cho ch\u1ebf ph\u1ea9m c\u00f3 pH cao; \u0111\u1ed3ng th\u1eddi l\u00e0 ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n hi\u1ec7u qu\u1ea3, nh\u1ea5t l\u00e0 v\u1edbi n\u1ea5m \u1edf pH […]<\/p>","protected":false},"author":1,"featured_media":2635,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2636","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-sulfit.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-sulfit-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-sulfit-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-sulfit-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-sulfit-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-sulfit.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-sulfit.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/natri-sulfit-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Natri sulfit (E221) \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a cho ch\u1ebf ph\u1ea9m pH ki\u1ec1m, b\u1ea3o qu\u1ea3n Natri sulfit (natri sulfit khan, Na2SO3, E221) l\u00e0 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a d\u00f9ng t\u01b0\u01a1ng t\u1ef1 natri metabisulfit nh\u01b0ng cho ch\u1ebf ph\u1ea9m c\u00f3 pH cao; \u0111\u1ed3ng th\u1eddi l\u00e0 ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n hi\u1ec7u qu\u1ea3, nh\u1ea5t l\u00e0 v\u1edbi n\u1ea5m \u1edf pH…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2636","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2636"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2636\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2635"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2636"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2636"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2636"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Th\u00f4ng tin nhanh<\/h2>\n
\n\n
\n T\u00ean kh\u00e1c<\/td>\n Anhydrous sodium sulfite, exsiccated sodium sulfite, disodium sulfite, sulfurous acid disodium salt, E221<\/td>\n<\/tr>\n \n S\u1ed1 CAS<\/td>\n 7757-83-7<\/td>\n<\/tr>\n \n C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\n Na2<\/sub>SO3<\/sub> \u2013 126,04<\/td>\n<\/tr>\n \n Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\n Ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n, ch\u1ea5t ch\u1ed1ng oxy h\u00f3a<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n Applications<\/h2>\n
\n
M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
\n
\u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n
T\u01b0\u01a1ng k\u1ef5<\/h2>\n
S\u1ea3n xu\u1ea5t<\/h2>\n
An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
\n
Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n
\nRowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5.
\nPharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006.
\nB\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n
\nTi\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh
\nhi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"