{"id":2560,"date":"2026-09-27T16:32:19","date_gmt":"2026-09-27T09:32:19","guid":{"rendered":"https:\/\/cpc1.vn\/kali-metabisulfit\/"},"modified":"2026-09-27T16:51:52","modified_gmt":"2026-09-27T09:51:52","slug":"kali-metabisulfit","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/kali-metabisulfit\/","title":{"rendered":"Kali metabisulfit (E224) \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a, b\u1ea3o qu\u1ea3n"},"content":{"rendered":"

Kali metabisulfit (E224) \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a, b\u1ea3o qu\u1ea3n<\/h1>\n

Kali metabisulfit<\/strong> (K2<\/sub>S2<\/sub>O5<\/sub>, kali pyrosulfit, E224) c\u00f3 \u1ee9ng d\u1ee5ng t\u01b0\u01a1ng t\u1ef1 natri metabisulfit trong d\u01b0\u1ee3c ph\u1ea9m v\u00e0 ng\u00e0nh th\u1ef1c ph\u1ea9m, bia, r\u01b0\u1ee3u vang: ch\u1ea5t ch\u1ed1ng oxy h\u00f3a<\/strong>, ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n<\/strong> v\u00e0 ch\u1ea5t kh\u1eed tr\u00f9ng thi\u1ebft b\u1ecb.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nDipotassium pyrosulfite, potassium pyrosulfite, kali disulfis, E224<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n16731-55-8<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nK2<\/sub>S2<\/sub>O5<\/sub> \u2013 222,32<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n, ch\u1ea5t ch\u1ed1ng oxy h\u00f3a<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • Ch\u1ea5t ch\u1ed1ng oxy h\u00f3a v\u00e0 b\u1ea3o qu\u1ea3n trong thu\u1ed1c ti\u00eam (b\u1eafp, t\u0129nh m\u1ea1ch), dung d\u1ecbch\/h\u1ed7n d\u1ecbch nh\u1ecf tai v\u00e0 tr\u1ef1c tr\u00e0ng.<\/li>\n
  • Th\u1ef1c ph\u1ea9m, s\u1ea3n xu\u1ea5t bia, r\u01b0\u1ee3u vang.<\/li>\n
  • Kh\u00f4ng n\u00ean d\u00f9ng trong th\u1ef1c ph\u1ea9m l\u00e0 ngu\u1ed3n thiamin (th\u1ecbt, rau qu\u1ea3 t\u01b0\u01a1i, khoai t\u00e2y t\u01b0\u01a1i\u2026) v\u00ec sulfit l\u00e0m vitamin B1 k\u00e9m b\u1ec1n.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Tinh th\u1ec3, b\u1ed9t k\u1ebft tinh ho\u1eb7c h\u1ea1t tr\u1eafng hay kh\u00f4ng m\u00e0u, tr\u01a1n ch\u1ea3y, th\u01b0\u1eddng c\u00f3 m\u00f9i SO2<\/sub>.<\/li>\n
    • pH dung d\u1ecbch 5%: 3,5\u20134,5; t\u1ef7 tr\u1ecdng bi\u1ec3u ki\u1ebfn 1,1\u20131,3 g\/cm\u00b3, g\u00f5 1,2\u20131,5 g\/cm\u00b3.<\/li>\n
    • Trong dung d\u1ecbch n\u01b0\u1edbc t\u1ea1o kali bisulfit (KHSO3<\/sub>) c\u00f3 t\u00ednh kh\u1eed m\u1ea1nh.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ea3o qu\u1ea3n n\u01a1i m\u00e1t, t\u1ed1i. \u1ede t\u1ed1i \u0111a 25 \u00b0C v\u00e0 \u0111\u1ed9 \u1ea9m t\u01b0\u01a1ng \u0111\u1ed1i t\u1ed1i \u0111a 45%, h\u1ea1n d\u00f9ng 6 th\u00e1ng. Ph\u00e2n h\u1ee7y tr\u00ean 150 \u00b0C. Trong kh\u00f4ng kh\u00ed b\u1ecb oxy h\u00f3a th\u00e0nh sulfat, nhanh h\u01a1n khi c\u00f3 \u1ea9m.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n
        \n
      • T\u01b0\u01a1ng k\u1ef5 v\u1edbi acid m\u1ea1nh (gi\u1ea3i ph\u00f3ng SO2<\/sub>), n\u01b0\u1edbc, h\u1ea7u h\u1ebft kim lo\u1ea1i th\u00f4ng d\u1ee5ng. Ph\u1ea3n \u1ee9ng v\u1edbi nitrit v\u00e0 natri nitrat \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng, \u0111\u00f4i khi b\u1ed1c l\u1eeda; c\u00f3 th\u1ec3 n\u1ed5 khi c\u00f3 n\u01b0\u1edbc.<\/li>\n
      • Sulfit ph\u1ea3n \u1ee9ng v\u1edbi nhi\u1ec1u d\u01b0\u1ee3c ch\u1ea5t \u2013 thu\u1ed1c c\u01b0\u1eddng giao c\u1ea3m nh\u01b0 epinephrin, cloramphenicol, cisplatin, acid amin \u2013 l\u00e0m m\u1ea5t ho\u1ea1t t\u00ednh; ph\u1ea3n \u1ee9ng v\u1edbi phenylmercuric nitrat; c\u00f3 th\u1ec3 h\u1ea5p ph\u1ee5 v\u00e0o n\u00fat cao su.<\/li>\n<\/ul>\n

        An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
          \n
        • D\u00f9ng trong th\u1ef1c ph\u1ea9m v\u00e0 thu\u1ed1c u\u1ed1ng, nh\u1ecf tai, tr\u1ef1c tr\u00e0ng, ti\u00eam. L\u00e0 ch\u1ea5t r\u1ea5t k\u00edch \u1ee9ng, c\u00f3 th\u1ec3 g\u00e2y vi\u00eam da \u1edf v\u00f9ng ti\u1ebfp x\u00fac.<\/li>\n
        • \u0110\u00e3 ghi nh\u1eadn qu\u00e1 m\u1eabn v\u1edbi sulfit (ch\u1ee7 y\u1ebfu t\u1eeb th\u1ef1c ph\u1ea9m) \u2013 co th\u1eaft ph\u1ebf qu\u1ea3n, ph\u1ea3n v\u1ec7, c\u00f3 ca t\u1eed vong, nh\u1ea5t l\u00e0 \u1edf ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed hen ho\u1eb7c d\u1ecb \u1ee9ng c\u01a1 \u0111\u1ecba; FDA \u0111\u00e3 h\u1ea1n ch\u1ebf sulfit trong th\u1ef1c ph\u1ea9m (kh\u00f4ng \u00e1p d\u1ee5ng cho d\u01b0\u1ee3c ph\u1ea9m).<\/li>\n
        • ADI nh\u00f3m sulfit (t\u00ednh theo SO2<\/sub>) theo JECFA: 0\u20130,7 mg\/kg th\u1ec3 tr\u1ecdng (s\u1ed1 li\u1ec7u in trong s\u00e1ch gi\u1eefa c\u00e1c chuy\u00ean lu\u1eadn kh\u00f4ng th\u1ed1ng nh\u1ea5t).<\/li>\n
        • \u0110eo g\u0103ng tay, k\u00ednh b\u1ea3o h\u1ed9; h\u1ea1n ch\u1ebf ti\u1ebfp x\u00fac ni\u00eam m\u1ea1c v\u00e0 \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p; khi \u0111un \u0111\u1ebfn ph\u00e2n h\u1ee7y t\u1ecfa kh\u00f3i \u0111\u1ed9c SO2<\/sub>.<\/li>\n<\/ul>\n

          T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
            \n
          • GRAS; \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn l\u00e0m ph\u1ee5 gia th\u1ef1c ph\u1ea9m t\u1ea1i ch\u00e2u \u00c2u cho m\u1ed9t s\u1ed1 \u1ee9ng d\u1ee5ng (E224).<\/li>\n
          • C\u00f3 trong FDA Inactive Ingredients Guide (ti\u00eam b\u1eafp, t\u0129nh m\u1ea1ch; dung d\u1ecbch, h\u1ed7n d\u1ecbch nh\u1ecf tai v\u00e0 tr\u1ef1c tr\u00e0ng); c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n
          • C\u00f3 chuy\u00ean lu\u1eadn trong USP-NF v\u00e0 Food Chemicals Codex.<\/li>\n<\/ul>\n

            Ch\u1ea5t li\u00ean quan:<\/strong> kali bisulfit (KHSO3<\/sub>, 120,2; CAS 7773-03-7; E228), natri metabisulfit, natri sulfit.<\/p>\n

            Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

            N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Potassium Metabisulfite<\/em> trong:
            \nRowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5.
            \nPharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006.
            \nB\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

            \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

            L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006.
            \nTi\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh
            \nhi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

            Kali metabisulfit (E224) \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a, b\u1ea3o qu\u1ea3n Kali metabisulfit (K2S2O5, kali pyrosulfit, E224) c\u00f3 \u1ee9ng d\u1ee5ng t\u01b0\u01a1ng t\u1ef1 natri metabisulfit trong d\u01b0\u1ee3c ph\u1ea9m v\u00e0 ng\u00e0nh th\u1ef1c ph\u1ea9m, bia, r\u01b0\u1ee3u vang: ch\u1ea5t ch\u1ed1ng oxy h\u00f3a, ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n v\u00e0 ch\u1ea5t kh\u1eed tr\u00f9ng thi\u1ebft b\u1ecb. Th\u00f4ng tin nhanh T\u00ean kh\u00e1c Dipotassium pyrosulfite, […]<\/p>","protected":false},"author":1,"featured_media":2559,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2560","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-metabisulfit.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-metabisulfit-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-metabisulfit-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-metabisulfit-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-metabisulfit-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-metabisulfit.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-metabisulfit.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-metabisulfit-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Kali metabisulfit (E224) \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a, b\u1ea3o qu\u1ea3n Kali metabisulfit (K2S2O5, kali pyrosulfit, E224) c\u00f3 \u1ee9ng d\u1ee5ng t\u01b0\u01a1ng t\u1ef1 natri metabisulfit trong d\u01b0\u1ee3c ph\u1ea9m v\u00e0 ng\u00e0nh th\u1ef1c ph\u1ea9m, bia, r\u01b0\u1ee3u vang: ch\u1ea5t ch\u1ed1ng oxy h\u00f3a, ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n v\u00e0 ch\u1ea5t kh\u1eed tr\u00f9ng thi\u1ebft b\u1ecb. Th\u00f4ng tin nhanh T\u00ean kh\u00e1c Dipotassium pyrosulfite,…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2560","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2560"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2560\/revisions"}],"predecessor-version":[{"id":2620,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2560\/revisions\/2620"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2559"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2560"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2560"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2560"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}