{"id":2550,"date":"2026-09-27T16:29:43","date_gmt":"2026-09-27T09:29:43","guid":{"rendered":"https:\/\/cpc1.vn\/kali-benzoat\/"},"modified":"2026-09-28T21:15:36","modified_gmt":"2026-09-28T14:15:36","slug":"kali-benzoat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/kali-benzoat\/","title":{"rendered":"Kali benzoat (E212) \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n thay natri benzoat khi c\u1ea7n \u00edt natri"},"content":{"rendered":"

Kali benzoat (E212) \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n thay natri benzoat khi c\u1ea7n \u00edt natri<\/h1>\n

Kali benzoat<\/strong> (E212) l\u00e0 mu\u1ed1i kali c\u1ee7a acid benzoic, ch\u1ee7 y\u1ebfu d\u00f9ng l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n<\/strong> trong \u0111\u1ed3 u\u1ed1ng, th\u1ef1c ph\u1ea9m v\u00e0 m\u1ed9t s\u1ed1 d\u01b0\u1ee3c ph\u1ea9m; ng\u00e0y c\u00e0ng \u0111\u01b0\u1ee3c d\u00f9ng thay natri benzoat<\/strong> khi c\u1ea7n h\u00e0m l\u01b0\u1ee3ng natri th\u1ea5p. Ngo\u00e0i ra c\u00f3 th\u1ec3 l\u00e0m t\u00e1 d\u01b0\u1ee3c tr\u01a1n vi\u00ean n\u00e9n, nang.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nBenzoate of potash, benzoic acid potassium salt, E212, kalium benzoat; ProBenz PG<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n582-25-2<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC7<\/sub>H5<\/sub>KO2<\/sub> \u2013 160,21<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n, t\u00e1 d\u01b0\u1ee3c tr\u01a1n vi\u00ean n\u00e9n v\u00e0 nang<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • Ch\u1ea5t b\u1ea3o qu\u1ea3n: hi\u1ec7u qu\u1ea3 t\u0103ng khi pH gi\u1ea3m, t\u1ed1t nh\u1ea5t \u1edf pH 4,5 tr\u1edf xu\u1ed1ng (d\u1ea1ng acid benzoic kh\u00f4ng ph\u00e2n ly); \u1edf pH th\u1ea5p acid benzoic c\u00f3 th\u1ec3 g\u00e2y v\u1ecb nh\u1eb9 nh\u1eadn bi\u1ebft \u0111\u01b0\u1ee3c trong th\u1ef1c ph\u1ea9m.<\/li>\n
  • Thay natri benzoat trong s\u1ea3n ph\u1ea9m c\u1ea7n \u00edt natri.<\/li>\n
  • N\u1ed3ng \u0111\u1ed9 tham kh\u1ea3o: \u0111\u1ed3 u\u1ed1ng c\u00f3 gas 0,03\u20130,08%; th\u1ef1c ph\u1ea9m \u2264 0,1%.<\/li>\n
  • \u1ee8ng d\u1ee5ng l\u00e0m thu\u1ed1c (b\u1ed5 sung kali) n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • B\u1ed9t k\u1ebft tinh ho\u1eb7c h\u1ea1t tr\u1eafng, h\u01a1i h\u00fat \u1ea9m, kh\u00f4ng m\u00f9i ho\u1eb7c g\u1ea7n nh\u01b0 kh\u00f4ng m\u00f9i.<\/li>\n
    • Dung d\u1ecbch n\u01b0\u1edbc h\u01a1i ki\u1ec1m; n\u00f3ng ch\u1ea3y tr\u00ean 300 \u00b0C; t\u1ef7 tr\u1ecdng 1,5.<\/li>\n
    • \u0110\u1ed9 tan: n\u01b0\u1edbc 1\/2,36 (20 \u00b0C; 1\/2,15 \u1edf 50 \u00b0C); ethanol 90% 1\/50; ethanol 95% 1\/75; r\u1ea5t kh\u00f3 tan trong methanol; h\u1ea7u nh\u01b0 kh\u00f4ng tan trong ether.<\/li>\n
    • USP-NF: n\u01b0\u1edbc \u2264 1,5%; h\u00e0m l\u01b0\u1ee3ng 99,0\u2013100,5% (ch\u1ebf ph\u1ea9m khan).<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ec1n \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng, \u0111i\u1ec1u ki\u1ec7n th\u01b0\u1eddng. H\u01a1i h\u00fat \u1ea9m \u2013 b\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, tr\u00e1nh \u0111\u1ed9 \u1ea9m cao v\u00e0 nhi\u1ec7t \u0111\u1ed9 cao.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi acid m\u1ea1nh v\u00e0 ch\u1ea5t oxy h\u00f3a m\u1ea1nh.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Ph\u1ea3n \u1ee9ng acid\u2013base gi\u1eefa acid benzoic v\u00e0 kali hydroxid.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

      D\u00f9ng r\u1ed9ng r\u00e3i trong th\u1ef1c ph\u1ea9m, n\u00f3i chung \u0111\u01b0\u1ee3c xem l\u00e0 kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng. Ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng c\u00f3 th\u1ec3 ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng; ng\u01b0\u1eddi hen kh\u00f4ng n\u00ean d\u00f9ng; n\u1ed3ng \u0111\u1ed9 cao c\u00f3 th\u1ec3 k\u00edch \u1ee9ng ni\u00eam m\u1ea1c. WHO \u0111\u1eb7t ADI t\u1ed5ng benzoat (t\u00ednh theo acid benzoic) \u0111\u1ebfn 5 mg\/kg th\u1ec3 tr\u1ecdng. C\u00f3 th\u1ec3 k\u00edch \u1ee9ng m\u1eaft, da \u2013 \u0111eo k\u00ednh b\u1ea3o h\u1ed9, g\u0103ng tay; khi \u0111un \u0111\u1ebfn ph\u00e2n h\u1ee7y t\u1ecfa kh\u00f3i cay, kh\u00ed k\u00edch \u1ee9ng.<\/p>\n

      T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
        \n
      • GRAS; ph\u1ee5 gia th\u1ef1c ph\u1ea9m \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn t\u1ea1i ch\u00e2u \u00c2u (E212); c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n
      • C\u00f3 chuy\u00ean lu\u1eadn trong USP-NF.<\/li>\n<\/ul>\n

        Ch\u1ea5t li\u00ean quan:<\/strong> acid benzoic, natri benzoat, kali sorbat.<\/p>\n

        Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

        N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Potassium Benzoate<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

        \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

        L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

        Kali benzoat (E212) \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n thay natri benzoat khi c\u1ea7n \u00edt natri Kali benzoat (E212) l\u00e0 mu\u1ed1i kali c\u1ee7a acid benzoic, ch\u1ee7 y\u1ebfu d\u00f9ng l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n trong \u0111\u1ed3 u\u1ed1ng, th\u1ef1c ph\u1ea9m v\u00e0 m\u1ed9t s\u1ed1 d\u01b0\u1ee3c ph\u1ea9m; ng\u00e0y c\u00e0ng \u0111\u01b0\u1ee3c d\u00f9ng thay natri benzoat khi c\u1ea7n h\u00e0m l\u01b0\u1ee3ng natri th\u1ea5p. […]<\/p>\n","protected":false},"author":1,"featured_media":2549,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2550","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-benzoat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-benzoat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-benzoat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-benzoat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-benzoat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-benzoat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-benzoat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-benzoat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Kali benzoat (E212) \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n thay natri benzoat khi c\u1ea7n \u00edt natri Kali benzoat (E212) l\u00e0 mu\u1ed1i kali c\u1ee7a acid benzoic, ch\u1ee7 y\u1ebfu d\u00f9ng l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n trong \u0111\u1ed3 u\u1ed1ng, th\u1ef1c ph\u1ea9m v\u00e0 m\u1ed9t s\u1ed1 d\u01b0\u1ee3c ph\u1ea9m; ng\u00e0y c\u00e0ng \u0111\u01b0\u1ee3c d\u00f9ng thay natri benzoat khi c\u1ea7n h\u00e0m l\u01b0\u1ee3ng natri th\u1ea5p.…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2550","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2550"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2550\/revisions"}],"predecessor-version":[{"id":3268,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2550\/revisions\/3268"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2549"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2550"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2550"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2550"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}