{"id":2548,"date":"2026-09-27T16:29:34","date_gmt":"2026-09-27T09:29:34","guid":{"rendered":"https:\/\/cpc1.vn\/kali-alginat\/"},"modified":"2026-09-28T21:15:31","modified_gmt":"2026-09-28T14:15:31","slug":"kali-alginat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/kali-alginat\/","title":{"rendered":"Kali alginat (E402) \u2013 ch\u1ea5t l\u00e0m \u0111\u1eb7c, \u1ed5n \u0111\u1ecbnh, t\u1ea1o gel"},"content":{"rendered":"

Kali alginat (E402) \u2013 ch\u1ea5t l\u00e0m \u0111\u1eb7c, \u1ed5n \u0111\u1ecbnh, t\u1ea1o gel<\/h1>\n

Kali alginat<\/strong> (E402) l\u00e0 mu\u1ed1i kali c\u1ee7a acid alginic \u2013 polyuronid g\u1ed3m c\u00e1c kh\u1ed1i acid D-mannuronic v\u00e0 L-guluronic t\u1eeb t\u1ea3o n\u00e2u. \u0110\u01b0\u1ee3c d\u00f9ng r\u1ed9ng r\u00e3i trong th\u1ef1c ph\u1ea9m l\u00e0m ch\u1ea5t \u1ed5n \u0111\u1ecbnh, l\u00e0m \u0111\u1eb7c, nh\u0169 h\u00f3a<\/strong>; trong d\u01b0\u1ee3c ph\u1ea9m hi\u1ec7n ch\u1ee7 y\u1ebfu \u1edf c\u00e1c h\u1ec7 hydrogel<\/strong> th\u1eed nghi\u1ec7m.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nAlginic acid potassium salt, potassium polymannuronate, E402; Improved Kelmar<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n9005-36-1<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c<\/td>\n(C6<\/sub>H7<\/sub>O6<\/sub>K)n<\/sub><\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t nh\u0169 h\u00f3a, ch\u1ea5t \u1ed5n \u0111\u1ecbnh, ch\u1ea5t t\u1ea1o h\u1ed7n d\u1ecbch, ch\u1ea5t l\u00e0m \u0111\u1eb7c<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Hai lo\u1ea1i \u0111\u01b0\u1eddng t\u1ea1o kh\u1ed1i d\u00e0i \u0111\u1ebfn 20 \u0111\u01a1n v\u1ecb; t\u1ef7 l\u1ec7 c\u00e1c kh\u1ed1i ph\u1ee5 thu\u1ed9c lo\u00e0i t\u1ea3o v\u00e0 b\u1ed9 ph\u1eadn t\u1ea3o s\u1eed d\u1ee5ng. S\u1ed1 l\u01b0\u1ee3ng, \u0111\u1ed9 d\u00e0i v\u00e0 tr\u00ecnh t\u1ef1 kh\u1ed1i mannuronat\/guluronat quy\u1ebft \u0111\u1ecbnh t\u00ednh ch\u1ea5t v\u1eadt l\u00fd c\u1ee7a alginat.<\/p>\n

Applications<\/h2>\n
    \n
  • Th\u1ef1c ph\u1ea9m: ch\u1ea5t \u1ed5n \u0111\u1ecbnh, l\u00e0m \u0111\u1eb7c, nh\u0169 h\u00f3a.<\/li>\n
  • D\u01b0\u1ee3c ph\u1ea9m: h\u1ec7 hydrogel th\u1eed nghi\u1ec7m \u2013 \u0111\u00e3 kh\u1ea3o s\u00e1t \u0111\u1ed9 nh\u1edbt, \u0111\u1ed9 d\u00ednh, \u0111\u1ed9 \u0111\u00e0n h\u1ed3i, \u0111\u1ed9 c\u1ee9ng, \u0111\u1ed9 k\u1ebft d\u00ednh c\u1ee7a hydrogel kali alginat; \u1ea3nh h\u01b0\u1edfng c\u1ee7a ion calci l\u00ean l\u01b0u bi\u1ebfn hydrogel procyanidin \u0111\u01b0\u1eddng u\u1ed1ng.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • B\u1ed9t d\u1ea1ng s\u1ee3i ho\u1eb7c h\u1ea1t tr\u1eafng \u0111\u1ebfn h\u01a1i v\u00e0ng, g\u1ea7n nh\u01b0 kh\u00f4ng m\u00f9i, kh\u00f4ng v\u1ecb. C\u1ee1 h\u1ea1t trung b\u00ecnh kho\u1ea3ng 150 \u00b5m (Improved Kelmar).<\/li>\n
    • Tan trong n\u01b0\u1edbc t\u1ea1o dung d\u1ecbch keo th\u00e2n n\u01b0\u1edbc nh\u1edbt; kh\u00f4ng tan trong ethanol 95% v\u00e0 dung d\u1ecbch n\u01b0\u1edbc\u2013c\u1ed3n tr\u00ean 30% c\u1ed3n, cloroform, ether v\u00e0 acid pH d\u01b0\u1edbi kho\u1ea3ng 3.<\/li>\n
    • Hydrat h\u00f3a d\u1ec5 trong n\u01b0\u1edbc n\u00f3ng ho\u1eb7c l\u1ea1nh; c\u1ea7n ph\u00e2n t\u00e1n t\u1ed1t \u0111\u1ec3 tr\u00e1nh v\u00f3n c\u1ee5c ch\u1eadm hydrat h\u00f3a.<\/li>\n
    • \u0110\u1ed9 nh\u1edbt: kho\u1ea3ng 400 mPa\u00b7s (1%); 4 320 mPa\u00b7s (2,5%); 31 100 mPa\u00b7s (4%). \u0110\u1ed9 nh\u1edbt t\u1ef7 l\u1ec7 v\u1edbi n\u1ed3ng \u0111\u1ed9 v\u00e0 KLPT; gi\u1ea3m thu\u1eadn ngh\u1ecbch khi t\u0103ng nhi\u1ec7t \u0111\u1ed9.<\/li>\n
    • Th\u00eam ion calci t\u1ea1o li\u00ean k\u1ebft ngang v\u00e0 gel; li\u00ean k\u1ebft m\u1ea1nh, nhi\u1ec1u th\u00ec gel kh\u00f4ng thu\u1eadn ngh\u1ecbch theo nhi\u1ec7t.<\/li>\n
    • Kh\u00f4ng c\u00f3 chuy\u00ean lu\u1eadn d\u01b0\u1ee3c \u0111i\u1ec3n; ti\u00eau chu\u1ea9n theo Food Chemicals Codex (h\u00e0m l\u01b0\u1ee3ng 89,2\u2013105,5%, m\u1ea5t kh\u1ed1i l\u01b0\u1ee3ng khi l\u00e0m kh\u00f4 \u2264 15%).<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      D\u1ea1ng r\u1eafn b\u1ec1n, kh\u00f4ng d\u1ec5 h\u1ecfng do vi sinh; theo th\u1eddi gian \u0111\u1ed9 tr\u00f9ng h\u1ee3p gi\u1ea3m ch\u1eadm l\u00e0m gi\u1ea3m \u0111\u1ed9 nh\u1edbt dung d\u1ecbch. Nhi\u1ec7t v\u00e0 \u1ea9m l\u00e0m gi\u1ea3m ch\u1ea5t l\u01b0\u1ee3ng \u2013 b\u1ea3o qu\u1ea3n d\u01b0\u1edbi 25 \u00b0C, kh\u00f4 r\u00e1o, bao b\u00ec k\u00edn. Dung d\u1ecbch b\u1ec1n \u1edf pH 4\u201310; ngo\u00e0i kho\u1ea3ng n\u00e0y b\u1ea3o qu\u1ea3n l\u00e2u g\u00e2y kh\u1eed tr\u00f9ng h\u1ee3p do th\u1ee7y ph\u00e2n; d\u01b0\u1edbi pH 4 c\u00f3 th\u1ec3 t\u1ea1o gel ho\u1eb7c t\u1ee7a. Ch\u1ebf ph\u1ea9m l\u1ecfng\/b\u00e1n r\u1eafn c\u1ea7n ch\u1ea5t b\u1ea3o qu\u1ea3n (natri benzoat, kali sorbat ho\u1eb7c paraben).<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t oxy h\u00f3a m\u1ea1nh.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      T\u1ea3o n\u00e2u \u0111\u01b0\u1ee3c kh\u1eed kho\u00e1ng, chi\u1ebft v\u00e0 k\u1ebft t\u1ee7a acid alginic; trung h\u00f2a t\u1ea1o kali alginat, s\u1ea5y kh\u00f4 v\u00e0 nghi\u1ec1n.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

      D\u00f9ng r\u1ed9ng r\u00e3i trong th\u1ef1c ph\u1ea9m; hi\u1ec7n m\u1edbi d\u00f9ng l\u00e0m t\u00e1 d\u01b0\u1ee3c trong c\u00f4ng th\u1ee9c th\u1eed nghi\u1ec7m. Thao t\u00e1c theo bi\u1ec7n ph\u00e1p th\u00f4ng th\u01b0\u1eddng; khi \u0111un \u0111\u1ebfn ph\u00e2n h\u1ee7y t\u1ecfa kh\u00f3i cay, kh\u00ed k\u00edch \u1ee9ng.<\/p>\n

      T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n

      GRAS; \u0111\u01b0\u1ee3c ph\u00e9p d\u00f9ng trong th\u1ef1c ph\u1ea9m t\u1ea1i M\u1ef9 v\u00e0 ch\u00e2u \u00c2u (E402).<\/p>\n

      Ch\u1ea5t li\u00ean quan:<\/strong> acid alginic, amoni alginat, calci alginat, propylen glycol alginat, natri alginat.<\/p>\n

      Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

      N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Potassium Alginate<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

      \u1ea2nh minh h\u1ecda: thi\u1ebft k\u1ebf c\u1ee7a CPC1.<\/em><\/p>\n

      L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

      Kali alginat (E402) \u2013 ch\u1ea5t l\u00e0m \u0111\u1eb7c, \u1ed5n \u0111\u1ecbnh, t\u1ea1o gel Kali alginat (E402) l\u00e0 mu\u1ed1i kali c\u1ee7a acid alginic \u2013 polyuronid g\u1ed3m c\u00e1c kh\u1ed1i acid D-mannuronic v\u00e0 L-guluronic t\u1eeb t\u1ea3o n\u00e2u. \u0110\u01b0\u1ee3c d\u00f9ng r\u1ed9ng r\u00e3i trong th\u1ef1c ph\u1ea9m l\u00e0m ch\u1ea5t \u1ed5n \u0111\u1ecbnh, l\u00e0m \u0111\u1eb7c, nh\u0169 h\u00f3a; trong d\u01b0\u1ee3c ph\u1ea9m hi\u1ec7n ch\u1ee7 y\u1ebfu \u1edf c\u00e1c […]<\/p>\n","protected":false},"author":1,"featured_media":2547,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2548","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-alginat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-alginat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-alginat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-alginat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-alginat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-alginat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-alginat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/kali-alginat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Kali alginat (E402) \u2013 ch\u1ea5t l\u00e0m \u0111\u1eb7c, \u1ed5n \u0111\u1ecbnh, t\u1ea1o gel Kali alginat (E402) l\u00e0 mu\u1ed1i kali c\u1ee7a acid alginic \u2013 polyuronid g\u1ed3m c\u00e1c kh\u1ed1i acid D-mannuronic v\u00e0 L-guluronic t\u1eeb t\u1ea3o n\u00e2u. \u0110\u01b0\u1ee3c d\u00f9ng r\u1ed9ng r\u00e3i trong th\u1ef1c ph\u1ea9m l\u00e0m ch\u1ea5t \u1ed5n \u0111\u1ecbnh, l\u00e0m \u0111\u1eb7c, nh\u0169 h\u00f3a; trong d\u01b0\u1ee3c ph\u1ea9m hi\u1ec7n ch\u1ee7 y\u1ebfu \u1edf c\u00e1c…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2548","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2548"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2548\/revisions"}],"predecessor-version":[{"id":3267,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2548\/revisions\/3267"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2547"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2548"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2548"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2548"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}