{"id":2507,"date":"2026-09-27T16:12:44","date_gmt":"2026-09-27T09:12:44","guid":{"rendered":"https:\/\/cpc1.vn\/phenoxyethanol\/"},"modified":"2026-09-28T21:22:17","modified_gmt":"2026-09-28T14:22:17","slug":"phenoxyethanol","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/phenoxyethanol\/","title":{"rendered":"Phenoxyethanol \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n cho m\u1ef9 ph\u1ea9m v\u00e0 thu\u1ed1c d\u00f9ng ngo\u00e0i"},"content":{"rendered":"

Phenoxyethanol \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n cho m\u1ef9 ph\u1ea9m v\u00e0 thu\u1ed1c d\u00f9ng ngo\u00e0i<\/h1>\n

Phenoxyethanol<\/strong> (2-phenoxyethanol) l\u00e0 ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n<\/strong> d\u00f9ng trong m\u1ef9 ph\u1ea9m v\u00e0 thu\u1ed1c d\u00f9ng ngo\u00e0i \u1edf n\u1ed3ng \u0111\u1ed9 0,5\u20131,0%<\/strong>, c\u0169ng d\u00f9ng l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n cho vaccin. Ph\u1ed5 t\u00e1c d\u1ee5ng h\u1eb9p n\u00ean th\u01b0\u1eddng ph\u1ed1i h\u1ee3p ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1c, nh\u1ea5t l\u00e0 paraben.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\n2-Phenoxyethanol, ethylene glycol monophenyl ether, phenoxetol<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n122-99-6<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC8<\/sub>H10<\/sub>O2<\/sub> \u2013 138,16<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n, ch\u1ea5t kh\u1eed khu\u1ea9n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • Ch\u1ea5t b\u1ea3o qu\u1ea3n trong m\u1ef9 ph\u1ea9m v\u00e0 thu\u1ed1c d\u00f9ng ngo\u00e0i 0,5\u20131,0%.<\/li>\n
  • Ch\u1ea5t b\u1ea3o qu\u1ea3n cho vaccin.<\/li>\n
  • Ph\u1ed5 h\u1eb9p \u2192 th\u01b0\u1eddng ph\u1ed1i h\u1ee3p paraben \u0111\u1ec3 m\u1edf r\u1ed9ng ph\u1ed5.<\/li>\n
  • C\u00e1c \u1ee9ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Ch\u1ea5t l\u1ecfng kh\u00f4ng m\u00e0u, h\u01a1i s\u00e1nh, m\u00f9i th\u01a1m nh\u1eb9 d\u1ec5 ch\u1ecbu, v\u1ecb n\u00f3ng.<\/li>\n
    • Ho\u1ea1t t\u00ednh:<\/strong> hi\u1ec7u qu\u1ea3 trong kho\u1ea3ng pH r\u1ed9ng, m\u1ea1nh v\u1edbi Pseudomonas aeruginosa<\/em>, k\u00e9m h\u01a1n v\u1edbi Proteus vulgaris<\/em> v\u00e0 vi khu\u1ea9n Gram \u00e2m kh\u00e1c. MIC (\u00b5g\/mL): P. aeruginosa<\/em> 3200, A. niger<\/em> 3300, E. coli<\/em> 3600, C. albicans<\/em> 5400, S. aureus<\/em> 8500.<\/li>\n
    • N\u00f3ng ch\u1ea3y 14 \u00b0C; s\u00f4i 245,2 \u00b0C; \u0111i\u1ec3m ch\u1edbp ch\u00e1y 121 \u00b0C (c\u1ed1c h\u1edf); t\u1ef7 tr\u1ecdng 1,11 (20 \u00b0C); chi\u1ebft su\u1ea5t 1,537\u20131,539; pH dung d\u1ecbch 1% l\u00e0 6,0.<\/li>\n
    • H\u1ec7 s\u1ed1 ph\u00e2n b\u1ed1 v\u1edbi n\u01b0\u1edbc: isopropyl palmitat 2,9; d\u1ea7u l\u1ea1c 2,6; d\u1ea7u kho\u00e1ng 0,3.<\/li>\n
    • \u0110\u1ed9 tan (20 \u00b0C): tr\u1ed9n l\u1eabn v\u1edbi aceton, ethanol 95%, glycerin; n\u01b0\u1edbc 1\/43; isopropyl palmitat 1\/26; d\u1ea7u \u00f4 liu, d\u1ea7u l\u1ea1c 1\/50; d\u1ea7u kho\u00e1ng 1\/143.<\/li>\n
    • Pha dung d\u1ecbch n\u01b0\u1edbc: l\u1eafc phenoxyethanol v\u1edbi n\u01b0\u1edbc n\u00f3ng \u0111\u1ebfn tan, \u0111\u1ec3 ngu\u1ed9i r\u1ed3i b\u1ed5 sung \u0111\u1ee7 th\u1ec3 t\u00edch.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      Dung d\u1ecbch n\u01b0\u1edbc b\u1ec1n, ti\u1ec7t khu\u1ea9n \u0111\u01b0\u1ee3c b\u1eb1ng h\u1ea5p. Nguy\u00ean li\u1ec7u b\u1ec1n; b\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      Ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n c\u00f3 th\u1ec3 gi\u1ea3m do t\u01b0\u01a1ng t\u00e1c v\u1edbi ch\u1ea5t di\u1ec7n ho\u1ea1t kh\u00f4ng ion v\u00e0 c\u00f3 th\u1ec3 do b\u1ecb PVC h\u1ea5p thu. Ho\u1ea1t t\u00ednh v\u1edbi P. aeruginosa<\/em> c\u00f3 th\u1ec3 gi\u1ea3m khi c\u00f3 d\u1eabn ch\u1ea5t cellulose (methylcellulose, natri carboxymethylcellulose, HPMC).<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Cho phenol ph\u1ea3n \u1ee9ng v\u1edbi ethylen oxid trong m\u00f4i tr\u01b0\u1eddng ki\u1ec1m.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

      G\u00e2y t\u00ea t\u1ea1i ch\u1ed7 \u1edf m\u00f4i, l\u01b0\u1ee1i v\u00e0 ni\u00eam m\u1ea1c. Nguy\u00ean ch\u1ea5t k\u00edch \u1ee9ng da v\u00e0 m\u1eaft m\u1ee9c trung b\u00ecnh; tr\u00ean th\u1ecf, dung d\u1ecbch 10% kh\u00f4ng k\u00edch \u1ee9ng da, 2% kh\u00f4ng k\u00edch \u1ee9ng m\u1eaft. Ph\u01a1i nhi\u1ec5m l\u00e2u d\u00e0i c\u00f3 th\u1ec3 g\u00e2y \u0111\u1ed9c th\u1ea7n kinh trung \u01b0\u01a1ng nh\u01b0 c\u00e1c dung m\u00f4i h\u1eefu c\u01a1 kh\u00e1c. LD50<\/sub> (chu\u1ed9t c\u1ed1ng, u\u1ed1ng): 1,26 g\/kg; (th\u1ecf, qua da): 5 g\/kg. N\u00ean \u0111eo k\u00ednh b\u1ea3o h\u1ed9 v\u00e0 g\u0103ng tay.<\/p>\n

      T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
        \n
      • C\u00f3 trong FDA Inactive Ingredients Guide (d\u00f9ng ngo\u00e0i); c\u00f3 trong thu\u1ed1c kh\u00f4ng ti\u00eam \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i Anh; c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n
      • Ngo\u00e0i s\u00e1ch:<\/em> trong m\u1ef9 ph\u1ea9m, EU gi\u1edbi h\u1ea1n phenoxyethanol t\u1ed1i \u0111a 1% \u2013 ki\u1ec3m tra quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh c\u1ee7a th\u1ecb tr\u01b0\u1eddng \u0111\u00edch.<\/li>\n
      • C\u00f3 chuy\u00ean lu\u1eadn trong BP, Ph.Eur. v\u00e0 USP-NF.<\/li>\n<\/ul>\n

        Ch\u1ea5t li\u00ean quan:<\/strong> clorobutanol; clorophenoxyethanol (C8<\/sub>H9<\/sub>ClO2<\/sub>, CAS 29533-21-9); phenoxypropanol (1-phenoxypropan-2-ol, CAS 4169-04-4); phenylethyl alcol; methylparaben.<\/p>\n

        Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

        N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Phenoxyethanol<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

        \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

        L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

        Phenoxyethanol \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n cho m\u1ef9 ph\u1ea9m v\u00e0 thu\u1ed1c d\u00f9ng ngo\u00e0i Phenoxyethanol (2-phenoxyethanol) l\u00e0 ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n d\u00f9ng trong m\u1ef9 ph\u1ea9m v\u00e0 thu\u1ed1c d\u00f9ng ngo\u00e0i \u1edf n\u1ed3ng \u0111\u1ed9 0,5\u20131,0%, c\u0169ng d\u00f9ng l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n cho vaccin. Ph\u1ed5 t\u00e1c d\u1ee5ng h\u1eb9p n\u00ean th\u01b0\u1eddng ph\u1ed1i h\u1ee3p ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1c, nh\u1ea5t l\u00e0 paraben. […]<\/p>","protected":false},"author":1,"featured_media":2506,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2507","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/phenoxyethanol.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/phenoxyethanol-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/phenoxyethanol-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/phenoxyethanol-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/phenoxyethanol-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/phenoxyethanol.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/phenoxyethanol.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/phenoxyethanol-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Phenoxyethanol \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n cho m\u1ef9 ph\u1ea9m v\u00e0 thu\u1ed1c d\u00f9ng ngo\u00e0i Phenoxyethanol (2-phenoxyethanol) l\u00e0 ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n d\u00f9ng trong m\u1ef9 ph\u1ea9m v\u00e0 thu\u1ed1c d\u00f9ng ngo\u00e0i \u1edf n\u1ed3ng \u0111\u1ed9 0,5\u20131,0%, c\u0169ng d\u00f9ng l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n cho vaccin. Ph\u1ed5 t\u00e1c d\u1ee5ng h\u1eb9p n\u00ean th\u01b0\u1eddng ph\u1ed1i h\u1ee3p ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1c, nh\u1ea5t l\u00e0 paraben.…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2507","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2507"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2507\/revisions"}],"predecessor-version":[{"id":3339,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2507\/revisions\/3339"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2506"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2507"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2507"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2507"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}