{"id":2481,"date":"2026-09-27T16:04:57","date_gmt":"2026-09-27T09:04:57","guid":{"rendered":"https:\/\/cpc1.vn\/nito\/"},"modified":"2026-09-27T16:04:57","modified_gmt":"2026-09-27T09:04:57","slug":"nito","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nito\/","title":{"rendered":"Nit\u01a1 (N2) \u2013 kh\u00ed \u0111\u1ea9y aerosol, kh\u00ed tr\u01a1 thay th\u1ebf kh\u00f4ng kh\u00ed"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Nit\u01a1 (N2) \u2013 kh\u00ed \u0111\u1ea9y aerosol, kh\u00ed tr\u01a1 thay th\u1ebf kh\u00f4ng kh\u00ed<\/h1>\n<p><strong>Nit\u01a1<\/strong> (N<sub>2<\/sub>, E941) chi\u1ebfm kho\u1ea3ng 78% th\u1ec3 t\u00edch kh\u00ed quy\u1ec3n \u2013 kh\u00ed kh\u00f4ng ph\u1ea3n \u1ee9ng, kh\u00f4ng ch\u00e1y, kh\u00f4ng m\u00e0u, kh\u00f4ng m\u00f9i, kh\u00f4ng v\u1ecb. Trong b\u00e0o ch\u1ebf, nit\u01a1 l\u00e0 <strong>kh\u00ed \u0111\u1ea9y d\u1ea1ng kh\u00ed n\u00e9n<\/strong> cho aerosol d\u00f9ng ngo\u00e0i v\u00e0 l\u00e0 <strong>kh\u00ed tr\u01a1 \u0111u\u1ed5i kh\u00f4ng kh\u00ed<\/strong> kh\u1ecfi dung d\u1ecbch v\u00e0 kho\u1ea3ng tr\u1ed1ng bao b\u00ec \u0111\u1ec3 ch\u1ed1ng oxy h\u00f3a.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean kh\u00e1c<\/td>\n<td>Azote, E941<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>7727-37-9<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\n<td>N<sub>2<\/sub> \u2013 28,01<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\n<td>Kh\u00ed \u0111\u1ea9y aerosol, kh\u00ed thay th\u1ebf kh\u00f4ng kh\u00ed<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Applications<\/h2>\n<ul>\n<li><strong>Kh\u00ed \u0111\u1ea9y aerosol d\u00f9ng ngo\u00e0i<\/strong> (c\u00f9ng CO<sub>2<\/sub>, N<sub>2<\/sub>O). Kh\u00f4ng tan trong n\u01b0\u1edbc v\u00e0 dung m\u00f4i n\u00ean t\u00e1ch ri\u00eang kh\u1ecfi c\u00f4ng th\u1ee9c.<\/li>\n<li><strong>Antioxidant Properties:<\/strong> s\u1ee5c kh\u00ed (sparging) \u0111u\u1ed5i kh\u00f4ng kh\u00ed kh\u1ecfi dung d\u1ecbch d\u1ec5 oxy h\u00f3a; thay kh\u00f4ng kh\u00ed \u1edf kho\u1ea3ng tr\u1ed1ng ph\u00eda tr\u00ean s\u1ea3n ph\u1ea9m trong bao b\u00ec cu\u1ed1i, v\u00ed d\u1ee5 \u1ed1ng ti\u00eam th\u1ee7y tinh. C\u0169ng d\u00f9ng t\u01b0\u01a1ng t\u1ef1 trong th\u1ef1c ph\u1ea9m.<\/li>\n<\/ul>\n<p><strong>\u01afu \u0111i\u1ec3m kh\u00ed n\u00e9n l\u00e0m kh\u00ed \u0111\u1ea9y:<\/strong> r\u1ebb, \u0111\u1ed9c t\u00ednh th\u1ea5p, g\u1ea7n nh\u01b0 kh\u00f4ng m\u00f9i, kh\u00f4ng v\u1ecb; \u00e1p su\u1ea5t \u00edt thay \u0111\u1ed5i theo nhi\u1ec7t \u0111\u1ed9 so v\u1edbi kh\u00ed h\u00f3a l\u1ecfng. <strong>Nh\u01b0\u1ee3c \u0111i\u1ec3m:<\/strong> kh\u00f4ng c\u00f3 &#8220;kho d\u1ef1 tr\u1eef&#8221; kh\u00ed \u0111\u1ea9y n\u00ean \u00e1p su\u1ea5t gi\u1ea3m d\u1ea7n khi d\u00f9ng, l\u00e0m thay \u0111\u1ed5i \u0111\u1eb7c t\u00ednh phun; d\u00f9ng ng\u01b0\u1ee3c b\u00ecnh s\u1ebd x\u1ea3 pha h\u01a1i v\u00e0 m\u1ea5t kh\u00ed \u0111\u1ea9y; tia phun r\u1ea5t \u01b0\u1edbt. Van ch\u1ec9 phun s\u1ea3n ph\u1ea9m b\u1ea5t k\u1ec3 t\u01b0 th\u1ebf b\u00ecnh v\u00e0 h\u1ec7 th\u1ed1ng m\u00e0ng ng\u0103n gi\u00fap h\u1ea1n ch\u1ebf c\u00e1c nh\u01b0\u1ee3c \u0111i\u1ec3m n\u00e0y.<\/p>\n<h2>M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>S\u00f4i \u2212195,8 \u00b0C; n\u00f3ng ch\u1ea3y \u2212210 \u00b0C; nhi\u1ec7t \u0111\u1ed9 t\u1edbi h\u1ea1n \u2212147,2 \u00b0C; \u00e1p su\u1ea5t t\u1edbi h\u1ea1n 3,39 MPa (33,49 atm).<\/li>\n<li>T\u1ef7 tr\u1ecdng h\u01a1i t\u01b0\u01a1ng \u0111\u1ed1i 0,97 (kh\u00f4ng kh\u00ed = 1); t\u1ef7 tr\u1ecdng tuy\u1ec7t \u0111\u1ed1i 1,25 g\/L \u1edf \u0111i\u1ec1u ki\u1ec7n ti\u00eau chu\u1ea9n.<\/li>\n<li>Kh\u00f4ng ch\u00e1y. H\u1ea7u nh\u01b0 kh\u00f4ng tan trong n\u01b0\u1edbc v\u00e0 \u0111a s\u1ed1 dung m\u00f4i; tan trong n\u01b0\u1edbc d\u01b0\u1edbi \u00e1p su\u1ea5t.<\/li>\n<li>C\u00f3 c\u00e1c c\u1ea5p nit\u01a1 th\u01b0\u01a1ng m\u1ea1i kh\u00e1c nhau, v\u00ed d\u1ee5 c\u1ea5p \u0111\u1ed9 \u1ea9m \u0111\u1eb7c bi\u1ec7t th\u1ea5p.<\/li>\n<\/ul>\n<h2>\u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n<p>B\u1ec1n, tr\u01a1 h\u00f3a h\u1ecdc. B\u1ea3o qu\u1ea3n trong b\u00ecnh kim lo\u1ea1i k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n<h2>T\u01b0\u01a1ng k\u1ef5<\/h2>\n<p>N\u00f3i chung t\u01b0\u01a1ng h\u1ee3p v\u1edbi h\u1ea7u h\u1ebft v\u1eadt li\u1ec7u trong d\u01b0\u1ee3c ph\u1ea9m v\u00e0 th\u1ef1c ph\u1ea9m.<\/p>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>Ch\u01b0ng c\u1ea5t ph\u00e2n \u0111o\u1ea1n kh\u00f4ng kh\u00ed h\u00f3a l\u1ecfng.<\/p>\n<h2>An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n<p>N\u00f3i chung \u0111\u01b0\u1ee3c xem l\u00e0 kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng, nh\u01b0ng l\u00e0 <strong>ch\u1ea5t g\u00e2y ng\u1ea1t<\/strong> \u2013 h\u00edt l\u01b0\u1ee3ng l\u1edbn nguy hi\u1ec3m. Thao t\u00e1c theo quy tr\u00ecnh d\u00e0nh cho b\u00ecnh kh\u00ed n\u00e9n\/h\u00f3a l\u1ecfng; \u0111eo k\u00ednh b\u1ea3o h\u1ed9, g\u0103ng tay, qu\u1ea7n \u00e1o b\u1ea3o h\u1ed9; l\u00e0m vi\u1ec7c n\u01a1i th\u00f4ng gi\u00f3; theo d\u00f5i n\u1ed3ng \u0111\u1ed9 oxy trong kh\u00f4ng kh\u00ed n\u01a1i l\u00e0m vi\u1ec7c, kh\u00f4ng \u0111\u1ec3 xu\u1ed1ng d\u01b0\u1edbi 19% th\u1ec3 t\u00edch \u1edf \u00e1p su\u1ea5t th\u01b0\u1eddng. \u1ede \u00e1p su\u1ea5t cao (l\u1eb7n s\u00e2u), nit\u01a1 h\u00f2a tan v\u00e0o m\u00e1u v\u00e0 m\u00f4 m\u1ee1; gi\u1ea3m \u00e1p qu\u00e1 nhanh c\u00f3 th\u1ec3 g\u00e2y b\u1ec7nh gi\u1ea3m \u00e1p.<\/p>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n<ul>\n<li>GRAS; ph\u1ee5 gia th\u1ef1c ph\u1ea9m \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn t\u1ea1i ch\u00e2u \u00c2u (E941).<\/li>\n<li>C\u00f3 trong FDA Inactive Ingredients Guide (thu\u1ed1c ti\u00eam; nha khoa; x\u1ecbt m\u0169i; dung d\u1ecbch u\u1ed1ng; gel tr\u1ef1c tr\u00e0ng); c\u00f3 trong thu\u1ed1c ti\u00eam v\u00e0 kh\u00f4ng ti\u00eam \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i Anh v\u00e0 M\u1ef9; c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n<li>C\u00f3 chuy\u00ean lu\u1eadn trong BP, JP, Ph.Eur., USP-NF v\u00e0 Food Chemicals Codex.<\/li>\n<\/ul>\n<p><strong>Ch\u1ea5t li\u00ean quan:<\/strong> carbon dioxid, nit\u01a1 oxid (N<sub>2<\/sub>O).<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<p>N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn <em>Nitrogen<\/em> trong:<br \/>\nRowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). <em>Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5.<br \/>\nPharmaceutical Press (London) &amp; American Pharmacists Association (Washington DC), 2006.<br \/>\nB\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n<p><em>\u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n<p><em>L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006.<br \/>\nTi\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh<br \/>\nhi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Nit\u01a1 (N2) \u2013 kh\u00ed \u0111\u1ea9y aerosol, kh\u00ed tr\u01a1 thay th\u1ebf kh\u00f4ng kh\u00ed Nit\u01a1 (N2, E941) chi\u1ebfm kho\u1ea3ng 78% th\u1ec3 t\u00edch kh\u00ed quy\u1ec3n \u2013 kh\u00ed kh\u00f4ng ph\u1ea3n \u1ee9ng, kh\u00f4ng ch\u00e1y, kh\u00f4ng m\u00e0u, kh\u00f4ng m\u00f9i, kh\u00f4ng v\u1ecb. Trong b\u00e0o ch\u1ebf, nit\u01a1 l\u00e0 kh\u00ed \u0111\u1ea9y d\u1ea1ng kh\u00ed n\u00e9n cho aerosol d\u00f9ng ngo\u00e0i v\u00e0 l\u00e0 kh\u00ed tr\u01a1 \u0111u\u1ed5i kh\u00f4ng [&hellip;]<\/p>","protected":false},"author":1,"featured_media":2480,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2481","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nito.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nito-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nito-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nito-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nito-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nito.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nito.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/nito-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Nit\u01a1 (N2) \u2013 kh\u00ed \u0111\u1ea9y aerosol, kh\u00ed tr\u01a1 thay th\u1ebf kh\u00f4ng kh\u00ed Nit\u01a1 (N2, E941) chi\u1ebfm kho\u1ea3ng 78% th\u1ec3 t\u00edch kh\u00ed quy\u1ec3n \u2013 kh\u00ed kh\u00f4ng ph\u1ea3n \u1ee9ng, kh\u00f4ng ch\u00e1y, kh\u00f4ng m\u00e0u, kh\u00f4ng m\u00f9i, kh\u00f4ng v\u1ecb. Trong b\u00e0o ch\u1ebf, nit\u01a1 l\u00e0 kh\u00ed \u0111\u1ea9y d\u1ea1ng kh\u00ed n\u00e9n cho aerosol d\u00f9ng ngo\u00e0i v\u00e0 l\u00e0 kh\u00ed tr\u01a1 \u0111u\u1ed5i kh\u00f4ng&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2481","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2481"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2481\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2480"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2481"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2481"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2481"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}