{"id":2477,"date":"2026-09-27T16:04:40","date_gmt":"2026-09-27T09:04:40","guid":{"rendered":"https:\/\/cpc1.vn\/acid-myristic\/"},"modified":"2026-09-28T21:02:34","modified_gmt":"2026-09-28T14:02:34","slug":"acid-myristic","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/acid-myristic\/","title":{"rendered":"Acid myristic \u2013 acid b\u00e9o C14 t\u0103ng th\u1ea5m qua da, nh\u0169 h\u00f3a, t\u00e1 d\u01b0\u1ee3c tr\u01a1n"},"content":{"rendered":"

Acid myristic \u2013 acid b\u00e9o C14 t\u0103ng th\u1ea5m qua da, nh\u0169 h\u00f3a, t\u00e1 d\u01b0\u1ee3c tr\u01a1n<\/h1>\n

Acid myristic<\/strong> (acid tetradecanoic) l\u00e0 acid b\u00e9o no C14, c\u00f3 trong b\u01a1 nh\u1ee5c \u0111\u1eadu kh\u1ea5u v\u00e0 h\u1ea7u h\u1ebft m\u1ee1 \u0111\u1ed9ng v\u1eadt, d\u1ea7u th\u1ef1c v\u1eadt. \u0110\u01b0\u1ee3c d\u00f9ng trong thu\u1ed1c u\u1ed1ng v\u00e0 d\u00f9ng ngo\u00e0i l\u00e0m ch\u1ea5t nh\u0169 h\u00f3a<\/strong>, ch\u1ea5t t\u0103ng th\u1ea5m qua da<\/strong> v\u00e0 t\u00e1 d\u01b0\u1ee3c tr\u01a1n<\/strong> vi\u00ean n\u00e9n, vi\u00ean nang.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nTetradecanoic acid, n-tetradecoic acid<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n544-63-8<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC14<\/sub>H28<\/sub>O2<\/sub> \u2013 228,37<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t nh\u0169 h\u00f3a, ch\u1ea5t t\u0103ng th\u1ea5m qua da, t\u00e1 d\u01b0\u1ee3c tr\u01a1n vi\u00ean n\u00e9n v\u00e0 nang<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • Thu\u1ed1c u\u1ed1ng v\u00e0 d\u00f9ng ngo\u00e0i.<\/li>\n
  • \u0110\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 l\u00e0m ch\u1ea5t t\u0103ng th\u1ea5m trong mi\u1ebfng d\u00e1n melatonin qua da (chu\u1ed9t c\u1ed1ng) v\u00e0 c\u00f4ng th\u1ee9c bupropion (tr\u00ean da ng\u01b0\u1eddi t\u1eed thi); c\u0169ng \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u cho c\u00f4ng th\u1ee9c oxymorphon v\u00e0 clobetasol 17-propionat d\u00f9ng ngo\u00e0i.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Ch\u1ea5t r\u1eafn k\u1ebft tinh tr\u1eafng, tr\u01a1n nh\u1eddn, m\u00f9i nh\u1eb9.<\/li>\n
    • N\u00f3ng ch\u1ea3y 54,5 \u00b0C; s\u00f4i 326,2 \u00b0C; \u0111i\u1ec3m ch\u1edbp ch\u00e1y > 110 \u00b0C; t\u1ef7 tr\u1ecdng 0,860\u20130,870.<\/li>\n
    • Tan trong aceton, benzen, cloroform, ethanol 95%, ether, dung m\u00f4i th\u01a1m v\u00e0 dung m\u00f4i clor h\u00f3a; h\u1ea7u nh\u01b0 kh\u00f4ng tan trong n\u01b0\u1edbc.<\/li>\n
    • Kh\u00f4ng c\u00f3 chuy\u00ean lu\u1eadn d\u01b0\u1ee3c \u0111i\u1ec3n; ti\u00eau chu\u1ea9n theo Food Chemicals Codex (ch\u1ec9 s\u1ed1 acid 242\u2013249, ch\u1ec9 s\u1ed1 iod \u2264 1,0, ch\u1ec9 s\u1ed1 x\u00e0 ph\u00f2ng h\u00f3a 242\u2013251, n\u00f3ng ch\u1ea3y 48\u201355,5 \u00b0C) v\u00e0 Japanese Pharmaceutical Excipients.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t oxy h\u00f3a m\u1ea1nh v\u00e0 base.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      C\u00f3 trong t\u1ef1 nhi\u00ean (b\u01a1 nh\u1ee5c \u0111\u1eadu kh\u1ea5u, m\u1ee1 v\u00e0 d\u1ea7u). T\u1ed5ng h\u1ee3p b\u1eb1ng \u0111i\u1ec7n ph\u00e2n methyl hydrogen adipat v\u1edbi acid decanoic, ho\u1eb7c oxy h\u00f3a alcol myristylic.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

      N\u00f3i chung \u0111\u01b0\u1ee3c xem l\u00e0 kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng \u1edf m\u1ee9c d\u00f9ng l\u00e0m t\u00e1 d\u01b0\u1ee3c; tuy nhi\u00ean \u1edf n\u1ed3ng \u0111\u1ed9 cao \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o k\u00edch \u1ee9ng m\u1eaft v\u00e0 da, \u0111\u1ed9c khi ti\u00eam t\u0129nh m\u1ea1ch; c\u00f3 d\u1eef li\u1ec7u v\u1ec1 \u0111\u1ed9t bi\u1ebfn. LD50<\/sub> (chu\u1ed9t c\u1ed1ng, u\u1ed1ng): > 10 g\/kg; (chu\u1ed9t nh\u1eaft, t\u0129nh m\u1ea1ch): 43 mg\/kg. Khi \u0111un \u0111\u1ebfn ph\u00e2n h\u1ee7y t\u1ecfa kh\u00f3i cay, kh\u00ed k\u00edch \u1ee9ng.<\/p>\n

      T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
        \n
      • GRAS.<\/li>\n
      • C\u00f3 trong FDA Inactive Ingredients Guide (nang u\u1ed1ng); c\u00f3 trong thu\u1ed1c kh\u00f4ng ti\u00eam \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i Anh.<\/li>\n<\/ul>\n

        Ch\u1ea5t li\u00ean quan<\/h2>\n
          \n
        • Alcol myristylic<\/strong> (C14<\/sub>H30<\/sub>O, 214,39; CAS 112-72-1): n\u00f3ng ch\u1ea3y 37\u201339 \u00b0C; h\u1ea7u nh\u01b0 kh\u00f4ng tan trong n\u01b0\u1edbc.<\/li>\n
        • Kali myristat<\/strong> (CAS 13429-27-1): ch\u1ea5t di\u1ec7n ho\u1ea1t, ch\u1ea5t nh\u0169 h\u00f3a.<\/li>\n
        • Natri myristat<\/strong> (CAS 822-12-8): ch\u1ea5t nh\u0169 h\u00f3a.<\/li>\n
        • Acid lauric, acid palmitic, acid stearic, isopropyl myristat.<\/li>\n<\/ul>\n

          Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

          N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Myristic Acid<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

          \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

          L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          Acid myristic \u2013 acid b\u00e9o C14 t\u0103ng th\u1ea5m qua da, nh\u0169 h\u00f3a, t\u00e1 d\u01b0\u1ee3c tr\u01a1n Acid myristic (acid tetradecanoic) l\u00e0 acid b\u00e9o no C14, c\u00f3 trong b\u01a1 nh\u1ee5c \u0111\u1eadu kh\u1ea5u v\u00e0 h\u1ea7u h\u1ebft m\u1ee1 \u0111\u1ed9ng v\u1eadt, d\u1ea7u th\u1ef1c v\u1eadt. \u0110\u01b0\u1ee3c d\u00f9ng trong thu\u1ed1c u\u1ed1ng v\u00e0 d\u00f9ng ngo\u00e0i l\u00e0m ch\u1ea5t nh\u0169 h\u00f3a, ch\u1ea5t t\u0103ng th\u1ea5m qua […]<\/p>","protected":false},"author":1,"featured_media":2476,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2477","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-myristic.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-myristic-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-myristic-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-myristic-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-myristic-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-myristic.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-myristic.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-myristic-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Acid myristic \u2013 acid b\u00e9o C14 t\u0103ng th\u1ea5m qua da, nh\u0169 h\u00f3a, t\u00e1 d\u01b0\u1ee3c tr\u01a1n Acid myristic (acid tetradecanoic) l\u00e0 acid b\u00e9o no C14, c\u00f3 trong b\u01a1 nh\u1ee5c \u0111\u1eadu kh\u1ea5u v\u00e0 h\u1ea7u h\u1ebft m\u1ee1 \u0111\u1ed9ng v\u1eadt, d\u1ea7u th\u1ef1c v\u1eadt. \u0110\u01b0\u1ee3c d\u00f9ng trong thu\u1ed1c u\u1ed1ng v\u00e0 d\u00f9ng ngo\u00e0i l\u00e0m ch\u1ea5t nh\u0169 h\u00f3a, ch\u1ea5t t\u0103ng th\u1ea5m qua…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2477","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2477"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2477\/revisions"}],"predecessor-version":[{"id":3123,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2477\/revisions\/3123"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2476"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2477"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2477"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2477"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}