{"id":2475,"date":"2026-09-27T16:03:20","date_gmt":"2026-09-27T09:03:20","guid":{"rendered":"https:\/\/cpc1.vn\/monothioglycerol\/"},"modified":"2026-09-28T21:19:05","modified_gmt":"2026-09-28T14:19:05","slug":"monothioglycerol","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/monothioglycerol\/","title":{"rendered":"Monothioglycerol \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a cho thu\u1ed1c ti\u00eam"},"content":{"rendered":"

Monothioglycerol \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a cho thu\u1ed1c ti\u00eam<\/h1>\n

Monothioglycerol<\/strong> (thioglycerin, 1-thioglycerol) l\u00e0 d\u1eabn xu\u1ea5t thiol c\u1ee7a glycerol, d\u00f9ng l\u00e0m ch\u1ea5t ch\u1ed1ng oxy h\u00f3a<\/strong> trong d\u01b0\u1ee3c ph\u1ea9m, ch\u1ee7 y\u1ebfu trong thu\u1ed1c ti\u00eam<\/strong>; ngo\u00e0i ra c\u00f3 ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n nh\u1ea5t \u0111\u1ecbnh.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\n1-Mercaptoglycerol, 1-mercapto-2,3-propanediol, 3-mercapto-1,2-propanediol, monothioglycerin, \u03b1-monothioglycerol, thioglycerin<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n96-27-5<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC3<\/sub>H8<\/sub>O2<\/sub>S \u2013 108,16<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n, ch\u1ea5t ch\u1ed1ng oxy h\u00f3a<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • Ch\u1ea5t ch\u1ed1ng oxy h\u00f3a, ch\u1ee7 y\u1ebfu trong thu\u1ed1c ti\u00eam (v\u00ed d\u1ee5 thu\u1ed1c ti\u00eam ch\u1ee9a d\u01b0\u1ee3c ch\u1ea5t nh\u1ea1y oxy).<\/li>\n
  • C\u00f3 m\u1ed9t s\u1ed1 ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n.<\/li>\n
  • D\u00f9ng r\u1ed9ng r\u00e3i trong m\u1ef9 ph\u1ea9m nh\u01b0 ch\u1ebf ph\u1ea9m t\u1ea9y l\u00f4ng.<\/li>\n
  • C\u00e1c \u1ee9ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Ch\u1ea5t l\u1ecfng s\u00e1nh, kh\u00f4ng m\u00e0u ho\u1eb7c v\u00e0ng nh\u1ea1t, h\u00fat \u1ea9m, m\u00f9i sulfid nh\u1eb9.<\/li>\n
    • pH dung d\u1ecbch 10%: 3,5\u20137,0; s\u00f4i 118 \u00b0C (\u00e1p su\u1ea5t gi\u1ea3m); \u0111i\u1ec3m ch\u1edbp ch\u00e1y 110 \u00b0C; chi\u1ebft su\u1ea5t 1,521\u20131,526 (25 \u00b0C); t\u1ef7 tr\u1ecdng 1,241\u20131,250.<\/li>\n
    • Tr\u1ed9n l\u1eabn v\u1edbi ethanol 95%; d\u1ec5 tan trong n\u01b0\u1edbc; h\u1ea7u nh\u01b0 kh\u00f4ng tan trong ether.<\/li>\n
    • USP-NF: n\u01b0\u1edbc \u2264 5,0%; selen \u2264 0,003%; h\u00e0m l\u01b0\u1ee3ng 97,0\u2013101,0% (ch\u1ebf ph\u1ea9m khan).<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      Kh\u00f4ng b\u1ec1n trong dung d\u1ecbch ki\u1ec1m. B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      C\u00f3 th\u1ec3 ph\u1ea3n \u1ee9ng v\u1edbi ch\u1ea5t oxy h\u00f3a.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      \u0110un dung d\u1ecbch 3-cloro-1,2-propanediol trong ethanol v\u1edbi kali bisulfid.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

      \u1ede n\u1ed3ng \u0111\u1ed9 d\u00f9ng l\u00e0m t\u00e1 d\u01b0\u1ee3c, n\u00f3i chung \u0111\u01b0\u1ee3c xem l\u00e0 t\u01b0\u01a1ng \u0111\u1ed1i kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng; d\u00f9ng trong thu\u1ed1c d\u00f9ng ngo\u00e0i v\u00e0 thu\u1ed1c ti\u00eam. Tuy nhi\u00ean monothioglycerol nguy\u00ean ch\u1ea5t \u0111\u01b0\u1ee3c xem l\u00e0 ch\u1ea5t \u0111\u1ed9c qua \u0111\u01b0\u1eddng ti\u00eam ph\u00fac m\u1ea1c v\u00e0 t\u0129nh m\u1ea1ch, v\u00e0 c\u00f3 b\u00e1o c\u00e1o g\u00e2y \u0111\u1ed9t bi\u1ebfn. LD50<\/sub> (chu\u1ed9t c\u1ed1ng, ti\u00eam ph\u00fac m\u1ea1c): 0,39 g\/kg; (th\u1ecf, t\u0129nh m\u1ea1ch): 0,25 g\/kg. D\u1ec5 ch\u00e1y khi g\u1eb7p nhi\u1ec7t ho\u1eb7c l\u1eeda; khi ph\u00e2n h\u1ee7y do nhi\u1ec7t t\u1ecfa kh\u00f3i \u0111\u1ed9c SOx<\/sub>.<\/p>\n

      T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
        \n
      • C\u00f3 trong FDA Inactive Ingredients Guide (ti\u00eam b\u1eafp, t\u0129nh m\u1ea1ch v\u00e0 c\u00e1c \u0111\u01b0\u1eddng ti\u00eam kh\u00e1c); c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n
      • C\u00f3 chuy\u00ean lu\u1eadn trong USP-NF.<\/li>\n<\/ul>\n

        Ch\u1ea5t li\u00ean quan:<\/strong> natri metabisulfit, natri bisulfit, acid ascorbic, cystein.<\/p>\n

        Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

        N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Monothioglycerol<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

        \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

        L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

        Monothioglycerol \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a cho thu\u1ed1c ti\u00eam Monothioglycerol (thioglycerin, 1-thioglycerol) l\u00e0 d\u1eabn xu\u1ea5t thiol c\u1ee7a glycerol, d\u00f9ng l\u00e0m ch\u1ea5t ch\u1ed1ng oxy h\u00f3a trong d\u01b0\u1ee3c ph\u1ea9m, ch\u1ee7 y\u1ebfu trong thu\u1ed1c ti\u00eam; ngo\u00e0i ra c\u00f3 ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n nh\u1ea5t \u0111\u1ecbnh. Th\u00f4ng tin nhanh T\u00ean kh\u00e1c 1-Mercaptoglycerol, 1-mercapto-2,3-propanediol, 3-mercapto-1,2-propanediol, monothioglycerin, \u03b1-monothioglycerol, thioglycerin S\u1ed1 CAS 96-27-5 […]<\/p>\n","protected":false},"author":1,"featured_media":2474,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2475","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/monothioglycerol.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/monothioglycerol-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/monothioglycerol-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/monothioglycerol-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/monothioglycerol-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/monothioglycerol.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/monothioglycerol.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/monothioglycerol-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Monothioglycerol \u2013 ch\u1ea5t ch\u1ed1ng oxy h\u00f3a cho thu\u1ed1c ti\u00eam Monothioglycerol (thioglycerin, 1-thioglycerol) l\u00e0 d\u1eabn xu\u1ea5t thiol c\u1ee7a glycerol, d\u00f9ng l\u00e0m ch\u1ea5t ch\u1ed1ng oxy h\u00f3a trong d\u01b0\u1ee3c ph\u1ea9m, ch\u1ee7 y\u1ebfu trong thu\u1ed1c ti\u00eam; ngo\u00e0i ra c\u00f3 ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n nh\u1ea5t \u0111\u1ecbnh. Th\u00f4ng tin nhanh T\u00ean kh\u00e1c 1-Mercaptoglycerol, 1-mercapto-2,3-propanediol, 3-mercapto-1,2-propanediol, monothioglycerin, \u03b1-monothioglycerol, thioglycerin S\u1ed1 CAS 96-27-5…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2475","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2475"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2475\/revisions"}],"predecessor-version":[{"id":3305,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2475\/revisions\/3305"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2474"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2475"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2475"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2475"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}