{"id":2473,"date":"2026-09-27T16:03:12","date_gmt":"2026-09-27T09:03:12","guid":{"rendered":"https:\/\/cpc1.vn\/mononatri-glutamat\/"},"modified":"2026-09-29T12:07:36","modified_gmt":"2026-09-29T05:07:36","slug":"mononatri-glutamat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/mononatri-glutamat\/","title":{"rendered":"Mononatri glutamat (MSG) \u2013 ch\u1ea5t \u0111i\u1ec1u v\u1ecb, ch\u1ea5t \u0111\u1ec7m"},"content":{"rendered":"

Mononatri glutamat (MSG) \u2013 ch\u1ea5t \u0111i\u1ec1u v\u1ecb, ch\u1ea5t \u0111\u1ec7m<\/h1>\n

Mononatri glutamat<\/strong> (MSG, E621, b\u1ed9t ng\u1ecdt) l\u00e0 mu\u1ed1i mononatri c\u1ee7a acid L-glutamic t\u1ef1 nhi\u00ean. Trong thu\u1ed1c u\u1ed1ng, MSG d\u00f9ng l\u00e0m ch\u1ea5t \u0111i\u1ec1u v\u1ecb<\/strong> v\u00e0 ch\u1ea5t \u0111\u1ec7m<\/strong> \u2013 v\u00ed d\u1ee5 ph\u1ed1i h\u1ee3p v\u1edbi \u0111\u01b0\u1eddng c\u1ea3i thi\u1ec7n v\u1ecb d\u01b0\u1ee3c ch\u1ea5t \u0111\u1eafng, gi\u1ea3m v\u1ecb kim lo\u1ea1i c\u1ee7a ch\u1ebf ph\u1ea9m l\u1ecfng ch\u1ee9a s\u1eaft.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nMSG, E621, sodium glutamate monohydrate, glutamic acid monosodium salt, natrii glutamas, monosodium L-glutamate monohydrate<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n142-47-2 (monohydrat)<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC5<\/sub>H8<\/sub>NO4<\/sub>Na \u2013 169,13 (khan); C5<\/sub>H8<\/sub>NO4<\/sub>Na\u00b7H2<\/sub>O \u2013 187,13 (monohydrat)<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t \u0111\u1ec7m, ch\u1ea5t \u0111i\u1ec1u v\u1ecb<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • Thu\u1ed1c u\u1ed1ng: ch\u1ea5t \u0111\u1ec7m v\u00e0 ch\u1ea5t \u0111i\u1ec1u v\u1ecb; ph\u1ed1i h\u1ee3p \u0111\u01b0\u1eddng c\u1ea3i thi\u1ec7n v\u1ecb d\u01b0\u1ee3c ch\u1ea5t \u0111\u1eafng; gi\u1ea3m v\u1ecb kim lo\u1ea1i c\u1ee7a ch\u1ea5t l\u1ecfng ch\u1ee9a s\u1eaft.<\/li>\n
  • \u1ee8ng d\u1ee5ng r\u1ed9ng nh\u1ea5t l\u00e0 \u0111i\u1ec1u v\u1ecb th\u1ef1c ph\u1ea9m: th\u01b0\u1eddng 0,2\u20130,9% trong th\u1ef1c ph\u1ea9m m\u1eb7n th\u00f4ng th\u01b0\u1eddng; m\u1ed9t s\u1ed1 s\u1ea3n ph\u1ea9m nh\u01b0 protein \u0111\u1eadu n\u00e0nh c\u00f3 th\u1ec3 ch\u1ee9a 10\u201330%.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Tinh th\u1ec3 tr\u1eafng tr\u01a1n ch\u1ea3y ho\u1eb7c b\u1ed9t k\u1ebft tinh, g\u1ea7n nh\u01b0 kh\u00f4ng m\u00f9i, v\u1ecb gi\u1ed1ng th\u1ecbt (umami).<\/li>\n
    • pH dung d\u1ecbch 0,2%: 7,0 (USP-NF: pH dung d\u1ecbch 5% 6,7\u20137,2); n\u00f3ng ch\u1ea3y 232 \u00b0C; g\u00f3c quay c\u1ef1c ri\u00eang +24,2\u00b0 \u0111\u1ebfn +25,5\u00b0 (8% trong HCl 1 N).<\/li>\n
    • Tan trong n\u01b0\u1edbc; h\u01a1i tan trong ethanol 95%.<\/li>\n
    • 32 g MSG monohydrat t\u01b0\u01a1ng \u0111\u01b0\u01a1ng kho\u1ea3ng 29 g MSG khan (theo t\u1ef7 l\u1ec7 KLPT).<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      Dung d\u1ecbch n\u01b0\u1edbc ti\u1ec7t khu\u1ea9n \u0111\u01b0\u1ee3c b\u1eb1ng h\u1ea5p. B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      L\u00ean men ngu\u1ed3n carbohydrat: ch\u00e2u \u00c2u v\u00e0 M\u1ef9 th\u01b0\u1eddng d\u00f9ng r\u1ec9 \u0111\u01b0\u1eddng c\u1ee7 c\u1ea3i; ch\u00e2u \u00c1 d\u00f9ng m\u00eda \u0111\u01b0\u1eddng, s\u1eafn (tapioca).<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n
        \n
      • D\u00f9ng r\u1ed9ng r\u00e3i trong th\u1ef1c ph\u1ea9m v\u00e0 thu\u1ed1c u\u1ed1ng. Theo s\u00e1ch, MSG \u0111\u01b0\u1ee3c xem l\u00e0 \u0111\u1ed9c t\u00ednh trung b\u00ecnh khi u\u1ed1ng ho\u1eb7c ti\u00eam t\u0129nh m\u1ea1ch; t\u00e1c d\u1ee5ng b\u1ea5t l\u1ee3i \u0111\u01b0\u1ee3c ghi nh\u1eadn g\u1ed3m bu\u1ed3n ng\u1ee7, \u1ea3o gi\u00e1c, \u0111au \u0111\u1ea7u, kh\u00f3 th\u1edf, bu\u1ed3n n\u00f4n, n\u00f4n, vi\u00eam da.<\/li>\n
      • “H\u1ed9i ch\u1ee9ng nh\u00e0 h\u00e0ng Trung Hoa”: kh\u1edfi \u0111\u1ea7u t\u1eeb t\u1ef1 b\u00e1o c\u00e1o c\u1ee7a m\u1ed9t b\u00e1c s\u0129 (t\u00ea, h\u1ed3i h\u1ed9p sau b\u1eefa \u0103n Trung Hoa), sau \u0111\u00f3 nhi\u1ec1u b\u00e1o c\u00e1o giai tho\u1ea1i \u1edf li\u1ec1u 1,5\u201312 g v\u1edbi c\u1ea3m gi\u00e1c d\u1ecb c\u1ea3m, n\u00f3ng r\u00e1t da, c\u0103ng t\u1ee9c m\u1eb7t, t\u1ee9c ng\u1ef1c; hi\u1ebfm \u1edf tr\u1ebb em. Tuy nhi\u00ean c\u00e1c th\u1eed nghi\u1ec7m m\u00f9 c\u00f3 \u0111\u1ed1i ch\u1ee9ng gi\u1ea3 d\u01b0\u1ee3c ph\u1ea7n l\u1edbn kh\u00f4ng t\u00e1i hi\u1ec7n \u0111\u01b0\u1ee3c \u0111\u1ea7y \u0111\u1ee7 h\u1ed9i ch\u1ee9ng; m\u1ed9t s\u1ed1 ph\u1ea3n \u1ee9ng ph\u1ee5 thu\u1ed9c li\u1ec1u c\u00f3 th\u1ec3 c\u00f3 (li\u1ec1u 5 g g\u00e2y ph\u1ea3n \u1ee9ng \u1edf kho\u1ea3ng 30% ng\u01b0\u1eddi th\u1eed).<\/li>\n
      • FDA cho r\u1eb1ng MSG v\u00e0 c\u00e1c ch\u1ea5t li\u00ean quan l\u00e0 th\u00e0nh ph\u1ea7n th\u1ef1c ph\u1ea9m an to\u00e0n v\u1edbi \u0111a s\u1ed1 ng\u01b0\u1eddi khi d\u00f9ng \u1edf m\u1ee9c th\u00f4ng th\u01b0\u1eddng.<\/li>\n
      • LD50<\/sub> (chu\u1ed9t c\u1ed1ng, u\u1ed1ng): 16,6 g\/kg; (chu\u1ed9t nh\u1eaft, u\u1ed1ng): 11,4 g\/kg.<\/li>\n
      • Thao t\u00e1c theo bi\u1ec7n ph\u00e1p th\u00f4ng th\u01b0\u1eddng; khi \u0111un \u0111\u1ebfn ph\u00e2n h\u1ee7y t\u1ecfa kh\u00f3i \u0111\u1ed9c NOx<\/sub>, Na2<\/sub>O.<\/li>\n<\/ul>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • GRAS; \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn l\u00e0m ph\u1ee5 gia th\u1ef1c ph\u1ea9m t\u1ea1i ch\u00e2u \u00c2u cho m\u1ed9t s\u1ed1 \u1ee9ng d\u1ee5ng (E621).<\/li>\n
        • C\u00f3 trong FDA Inactive Ingredients Guide (siro u\u1ed1ng); c\u00f3 trong thu\u1ed1c kh\u00f4ng d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i Anh.<\/li>\n
        • C\u00f3 chuy\u00ean lu\u1eadn trong USP-NF (h\u00e0m l\u01b0\u1ee3ng 99,0\u2013100,5%).<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan:<\/strong> acid glutamic, kali glutamat.<\/p>\n

          Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

          N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Monosodium Glutamate<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

          \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

          L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          Mononatri glutamat (MSG) \u2013 ch\u1ea5t \u0111i\u1ec1u v\u1ecb, ch\u1ea5t \u0111\u1ec7m Mononatri glutamat (MSG, E621, b\u1ed9t ng\u1ecdt) l\u00e0 mu\u1ed1i mononatri c\u1ee7a acid L-glutamic t\u1ef1 nhi\u00ean. Trong thu\u1ed1c u\u1ed1ng, MSG d\u00f9ng l\u00e0m ch\u1ea5t \u0111i\u1ec1u v\u1ecb v\u00e0 ch\u1ea5t \u0111\u1ec7m \u2013 v\u00ed d\u1ee5 ph\u1ed1i h\u1ee3p v\u1edbi \u0111\u01b0\u1eddng c\u1ea3i thi\u1ec7n v\u1ecb d\u01b0\u1ee3c ch\u1ea5t \u0111\u1eafng, gi\u1ea3m v\u1ecb kim lo\u1ea1i c\u1ee7a ch\u1ebf ph\u1ea9m […]<\/p>\n","protected":false},"author":1,"featured_media":2472,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2473","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mononatri-glutamat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mononatri-glutamat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mononatri-glutamat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mononatri-glutamat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mononatri-glutamat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mononatri-glutamat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mononatri-glutamat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/mononatri-glutamat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Mononatri glutamat (MSG) \u2013 ch\u1ea5t \u0111i\u1ec1u v\u1ecb, ch\u1ea5t \u0111\u1ec7m Mononatri glutamat (MSG, E621, b\u1ed9t ng\u1ecdt) l\u00e0 mu\u1ed1i mononatri c\u1ee7a acid L-glutamic t\u1ef1 nhi\u00ean. Trong thu\u1ed1c u\u1ed1ng, MSG d\u00f9ng l\u00e0m ch\u1ea5t \u0111i\u1ec1u v\u1ecb v\u00e0 ch\u1ea5t \u0111\u1ec7m \u2013 v\u00ed d\u1ee5 ph\u1ed1i h\u1ee3p v\u1edbi \u0111\u01b0\u1eddng c\u1ea3i thi\u1ec7n v\u1ecb d\u01b0\u1ee3c ch\u1ea5t \u0111\u1eafng, gi\u1ea3m v\u1ecb kim lo\u1ea1i c\u1ee7a ch\u1ebf ph\u1ea9m…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2473","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2473"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2473\/revisions"}],"predecessor-version":[{"id":3885,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2473\/revisions\/3885"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2472"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2473"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2473"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2473"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}