{"id":2434,"date":"2026-09-27T15:49:58","date_gmt":"2026-09-27T08:49:58","guid":{"rendered":"https:\/\/cpc1.vn\/magnesi-silicat\/"},"modified":"2026-09-28T21:17:42","modified_gmt":"2026-09-28T14:17:42","slug":"magnesi-silicat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/magnesi-silicat\/","title":{"rendered":"Magnesi silicat \u2013 ch\u1ea5t ch\u1ed1ng v\u00f3n, h\u1ed7 tr\u1ee3 tr\u01a1n ch\u1ea3y"},"content":{"rendered":"

Magnesi silicat \u2013 ch\u1ea5t ch\u1ed1ng v\u00f3n, h\u1ed7 tr\u1ee3 tr\u01a1n ch\u1ea3y<\/h1>\n

Magnesi silicat<\/strong> (magnesi silicat t\u1ed5ng h\u1ee3p, E553a) l\u00e0 h\u1ee3p ch\u1ea5t c\u1ee7a magnesi oxid v\u00e0 silic dioxid ng\u1eadm n\u01b0\u1edbc (MgO\u00b7SiO2<\/sub>\u00b7xH2<\/sub>O). \u0110\u01b0\u1ee3c d\u00f9ng trong thu\u1ed1c u\u1ed1ng v\u00e0 th\u1ef1c ph\u1ea9m l\u00e0m ch\u1ea5t h\u1ed7 tr\u1ee3 tr\u01a1n ch\u1ea3y<\/strong> v\u00e0 ch\u1ea5t ch\u1ed1ng v\u00f3n<\/strong>.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nSynthetic magnesium silicate, silicic acid magnesium salt, E553a<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n1343-88-0<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c<\/td>\nMgO\u00b7SiO2<\/sub>\u00b7xH2<\/sub>O<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t ch\u1ed1ng v\u00f3n, ch\u1ea5t h\u1ed7 tr\u1ee3 tr\u01a1n ch\u1ea3y<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Th\u00e0nh ph\u1ea7n theo d\u01b0\u1ee3c \u0111i\u1ec3n:<\/strong> JP \u2013 SiO2<\/sub> \u2265 45,0%, MgO \u2265 20,0%, t\u1ef7 l\u1ec7 % SiO2<\/sub>\/MgO t\u1eeb 2,2 \u0111\u1ebfn 2,5; USP-NF \u2013 MgO \u2265 15,0% v\u00e0 SiO2<\/sub> \u2265 67,0% t\u00ednh tr\u00ean ch\u1ebf ph\u1ea9m \u0111\u00e3 nung.<\/p>\n

Applications<\/h2>\n
    \n
  • Ch\u1ea5t h\u1ed7 tr\u1ee3 tr\u01a1n ch\u1ea3y v\u00e0 ch\u1ed1ng v\u00f3n trong thu\u1ed1c u\u1ed1ng d\u1ea1ng r\u1eafn.<\/li>\n
  • Ch\u1ea5t ch\u1ed1ng v\u00f3n trong th\u1ef1c ph\u1ea9m.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • B\u1ed9t m\u1ecbn m\u00e0u tr\u1eafng, kh\u00f4ng m\u00f9i, kh\u00f4ng v\u1ecb, kh\u00f4ng s\u1ea1n.<\/li>\n
    • H\u01a1i h\u00fat \u1ea9m.<\/li>\n
    • H\u1ea7u nh\u01b0 kh\u00f4ng tan trong n\u01b0\u1edbc, ethanol 95%, ether; b\u1ecb acid v\u00f4 c\u01a1 ph\u00e2n h\u1ee7y d\u1ec5 d\u00e0ng.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n
        \n
      • C\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m sinh kh\u1ea3 d\u1ee5ng \u0111\u01b0\u1eddng u\u1ed1ng c\u1ee7a mebeverin hydroclorid, sucralfat, tetracyclin do t\u1ea1o chelat ho\u1eb7c g\u1eafn k\u1ebft.<\/li>\n
      • H\u1ea5p ph\u1ee5 l\u00e0m ch\u1eadm h\u00f2a tan acid folic, erythromycin stearat, paracetamol, cloroquin phosphat.<\/li>\n
      • C\u00f3 th\u1ec3 l\u00e0m b\u1ea5t ho\u1ea1t ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n nh\u01b0 paraben.<\/li>\n
      • B\u1ecb acid v\u00f4 c\u01a1 ph\u00e2n h\u1ee7y.<\/li>\n<\/ul>\n

        S\u1ea3n xu\u1ea5t<\/h2>\n

        \u0110i\u1ec1u ch\u1ebf t\u1eeb natri silicat v\u00e0 magnesi sulfat. Trong t\u1ef1 nhi\u00ean, magnesi silicat c\u00f3 trong c\u00e1c kho\u00e1ng meerschaum, parasepiolit, sepiolit.<\/p>\n

        An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

        N\u00f3i chung \u0111\u01b0\u1ee3c xem l\u00e0 v\u1ec1 c\u01a1 b\u1ea3n kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng khi d\u00f9ng trong thu\u1ed1c u\u1ed1ng. Trong d\u1ea1 d\u00e0y, magnesi silicat b\u1ecb trung h\u00f2a t\u1ea1o magnesi clorid v\u00e0 silic dioxid; m\u1ed9t ph\u1ea7n magnesi \u0111\u01b0\u1ee3c h\u1ea5p thu \u2013 th\u1eadn tr\u1ecdng khi \u0111\u01b0a v\u00e0o tr\u00ean 50 mEq magnesi\/ng\u00e0y \u1edf ng\u01b0\u1eddi suy th\u1eadn (nguy c\u01a1 t\u0103ng magnesi m\u00e1u). \u0110\u00e3 c\u00f3 b\u00e1o c\u00e1o s\u1ecfi b\u00e0ng quang v\u00e0 s\u1ecfi th\u1eadn sau nhi\u1ec1u n\u0103m d\u00f9ng th\u01b0\u1eddng xuy\u00ean magnesi silicat v\u1edbi li\u1ec1u l\u00e0m thu\u1ed1c kh\u00e1ng acid. N\u00ean \u0111eo k\u00ednh b\u1ea3o h\u1ed9 khi thao t\u00e1c.<\/p>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • GRAS; ph\u1ee5 gia th\u1ef1c ph\u1ea9m \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn t\u1ea1i ch\u00e2u \u00c2u (E553a).<\/li>\n
        • C\u00f3 trong FDA Inactive Ingredients Guide (vi\u00ean n\u00e9n u\u1ed1ng); c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n
        • C\u00f3 chuy\u00ean lu\u1eadn trong JP, USP-NF v\u00e0 Food Chemicals Codex.<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan<\/h2>\n
            \n
          • Magnesi metasilicat<\/strong> (MgSiO3<\/sub>): c\u00f3 trong t\u1ef1 nhi\u00ean d\u01b0\u1edbi d\u1ea1ng kho\u00e1ng enstatit, clinoenstatit, protoenstatit.<\/li>\n
          • Magnesi orthosilicat<\/strong> (Mg2<\/sub>SiO4<\/sub>): kho\u00e1ng forsterit.<\/li>\n
          • Magnesi nh\u00f4m silicat, magnesi trisilicat, talc.<\/li>\n<\/ul>\n

            Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

            N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Magnesium Silicate<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

            \u1ea2nh minh h\u1ecda: thi\u1ebft k\u1ebf c\u1ee7a CPC1.<\/em><\/p>\n

            L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

            Magnesi silicat \u2013 ch\u1ea5t ch\u1ed1ng v\u00f3n, h\u1ed7 tr\u1ee3 tr\u01a1n ch\u1ea3y Magnesi silicat (magnesi silicat t\u1ed5ng h\u1ee3p, E553a) l\u00e0 h\u1ee3p ch\u1ea5t c\u1ee7a magnesi oxid v\u00e0 silic dioxid ng\u1eadm n\u01b0\u1edbc (MgO\u00b7SiO2\u00b7xH2O). \u0110\u01b0\u1ee3c d\u00f9ng trong thu\u1ed1c u\u1ed1ng v\u00e0 th\u1ef1c ph\u1ea9m l\u00e0m ch\u1ea5t h\u1ed7 tr\u1ee3 tr\u01a1n ch\u1ea3y v\u00e0 ch\u1ea5t ch\u1ed1ng v\u00f3n. Th\u00f4ng tin nhanh T\u00ean kh\u00e1c Synthetic magnesium silicate, […]<\/p>","protected":false},"author":1,"featured_media":2433,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2434","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/magnesi-silicat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/magnesi-silicat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/magnesi-silicat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/magnesi-silicat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/magnesi-silicat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/magnesi-silicat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/magnesi-silicat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/magnesi-silicat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Magnesi silicat \u2013 ch\u1ea5t ch\u1ed1ng v\u00f3n, h\u1ed7 tr\u1ee3 tr\u01a1n ch\u1ea3y Magnesi silicat (magnesi silicat t\u1ed5ng h\u1ee3p, E553a) l\u00e0 h\u1ee3p ch\u1ea5t c\u1ee7a magnesi oxid v\u00e0 silic dioxid ng\u1eadm n\u01b0\u1edbc (MgO\u00b7SiO2\u00b7xH2O). \u0110\u01b0\u1ee3c d\u00f9ng trong thu\u1ed1c u\u1ed1ng v\u00e0 th\u1ef1c ph\u1ea9m l\u00e0m ch\u1ea5t h\u1ed7 tr\u1ee3 tr\u01a1n ch\u1ea3y v\u00e0 ch\u1ea5t ch\u1ed1ng v\u00f3n. Th\u00f4ng tin nhanh T\u00ean kh\u00e1c Synthetic magnesium silicate,…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2434","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2434"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2434\/revisions"}],"predecessor-version":[{"id":3290,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2434\/revisions\/3290"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2433"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2434"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2434"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2434"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}